Integrative deep immune profiling of the elderly reveals systems-level signatures of aging, sex, smoking, and clinical traitsResearch in context by Lennart Riemann, Rodrigo Gutierrez, Ivan Odak, Joana Barros-Martins, Lennart M. Roesner, Ximena Leon Lara, Christine Falk, Thomas F. Schulz, Gesine Hansen, Thomas Werfel, Reinhold Förster, Berislav Bošnjak, Felix Jenniches, Norman Klopp, Till Robin Lesker, Martin Stangel

“…Studying the human immune system, however, remains challenging due to its complexity and significant inter-individual variability. Methods: We conducted an immune profiling study of 550 elderly participants (≥60 years) and 100 young controls (20–40 years) from the RESIST Senior Individuals (SI) cohort. …”
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Brain compensatory activation during Stroop task in patients with mild cognitive impairment: a functional near-infrared spectroscopy study by Chenyu Fan, Hanfei Li, Hanfei Li, Ke Chen, Ke Chen, Guohui Yang, Hongyu Xie, Haozheng Li, Yi Wu, Meng Li, Meng Li, Meng Li

“…PurposeThis study investigated the disparities in brain activation patterns during the Stroop task among individuals with mild cognitive impairment (MCI) and those without any cognitive impairments (healthy controls, HCs) using functional near-infrared spectroscopy (fNIRS).MethodsWe analyzed the cortical activation patterns of 73 patients with MCI and 63 HC individuals as they completed the Stroop task, employing fNIRS. …”
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Obesity and polysomnographic variables on patients with obstructive sleep apnea by Chaiane Facco Piccin, Marco Colomé Beck, Luiz Carlos Alves de Oliveira, Reinaldo Fernando Cóser Neto, Pedro Luis Cóser, Fabrício Scapini, Antônio Marcos Vargas da Silva

“…The combination of these changes demonstrates low quality of sleep on obese individuals, in relation to eutrophic or overweight individuals.…”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…This potential subject population includes individuals with broadly reactive antibodies who are unlikely to match to a donor organ and individuals with anatomical contraindications who face prohibitive risks with standard allografts or bridging therapies.…”
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An Unusual Case of Cystic Fibrosis Associated Pneumocystis jiroveci Pneumonia in an Infant by Ravinder Kaur, Priyanka Katariya, Megh Singh Dhakad, Bhanu Mehra, Urmila Jhamb, A. P. Dubey

“…The entity is common in HIV-seropositive individuals but quite very rare in HIV-seronegative individuals especially children. …”
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Patent Foramen Ovale in Patients with Sickle Cell Disease and Stroke: Case Presentations and Review of the Literature by Sheila Razdan, John J. Strouse, Rakhi Naik, Sophie Lanzkron, Victor Urrutia, Jon R. Resar, Linda M. S. Resar

“…Although individuals with sickle cell disease (SCD) are at increased risk for stroke, the underlying pathophysiology is incompletely understood. …”
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Humoral Autoimmune Responses to Insulin-Like Growth Factor II mRNA-Binding Proteins IMP1 and p62/IMP2 in Ovarian Cancer by Xinxin Liu, Hua Ye, Liuxia Li, Wenjie Li, Yi Zhang, Jian-Ying Zhang

“…In this study, autoantibody responses to two members (IMP1 and p62/IMP2) of IMPs were evaluated by enzyme-linked immunosorbent assay (ELISA), western blotting, and indirect immunofluorescence assay in sera from patients with ovarian cancer and normal human individuals. The results have demonstrated that both IMP1 and p62/IMP2 can induce relatively higher frequency of autoantibody responses in patients with ovarian cancer (26.5% and 29.4%) compared to normal individuals (P<0.01). …”
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HuBot: A biomimicking mobile robot for non-disruptive bird behavior study by Lyes Saad Saoud, Loïc Lesobre, Enrico Sorato, Saud Al Qaydi, Yves Hingrat, Lakmal Seneviratne, Irfan Hussain

“…By employing advanced real-time deep-learning algorithms, including YOLOv9 for detection, MobileSAM for segmentation, and vision transformer (ViT) for depth estimation, HuBot semi-autonomously tracks individual birds, providing unprecedented insights into their individual behavior, social interactions, and habitat use. …”
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Explanation of Behavioral Intentions to Mitigate Climate Change with Protection Motivation Theory by Nuran Bayram Arlı, Fırat Demir, Sedat Karakaya, Onur Barca, Furkan Onur Usluer

“…The behavioral intentions of individuals to prevent climate change were analyzed with the Structural Equation Model (SEM). …”
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Daily brisk walking increases intestinal acetic acid in short-chain fatty adults in healthy young adults: A randomized controlled trial by Emiko Morita, Suguru Ando, Yumi Fukuyama, Yui Kikuchi, Sho Kumabe, Yoshihiro Yamashina

“…Conclusion: Daily brisk walking for 20 minutes enhances acetic acid production by fostering the proliferation of Bifidobacterium in young individuals.…”
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The mRNA-1647 vaccine: A promising step toward the prevention of cytomegalovirus infection (CMV) by Adewunmi Akingbola, Abiodun Adegbesan, Olajumoke Adewole, Kolade Adegoke, Akpevwe Emmanuella Benson, Paul Ayomide Jombo, Sandra Uchechukwu Eboson, Victor Oluwasola, Ademola Aiyenuro

“…Cytomegalovirus (CMV) is a leading cause of congenital infections and significant health complications in immunocompromised individuals. With no licensed CMV vaccine available, the development of the mRNA-1647 offers promising advancements in CMV prevention. …”
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Transgender people and travestis experiencing homelessness in Salvador: a descriptive study on sociodemographic profile and access to social assistance and health services, Brazil,... by Wiler de Paula Dias, Thayane Silva Nunes, Igor Myron Ribeiro Nascimento, Erik Asley Ferreira Abade, Lua Sá Dultra, Milena Lemos Marinho, Guilherme de Sousa Ribeiro, Joilda Silva Nery

“…Results The sample was predominantly comprised of trans women and travestis (n=18), young individuals (n=13), of Black race/skin color (n=22), single individuals (n=18) and those engaged in informal occupations (n=23), many of whom reported experiencing violence (n=17). …”
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Spatial Spread of Tuberculosis through Neighborhoods Segregated by Socioeconomic Position: A Stochastic Automata Model by David Rehkopf, Alice Furumoto-Dawson, Anthony Kiszewski, Tamara Awerbuch-Friedlander

“…A cellular automata model is used to (a) construct neighborhoods of different densities, (b) model stochastically local interactions among individuals, and (c) model the spread of tuberculosis within and across neighborhoods over time. …”
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BIM Adoption in Construction Companies of Tehran Province, Using Technology Acceptance Model (TAM) by Sahar Taheripour, Mojtaba Azizi, Ehsanallah Eshtehardian

“…Both of these variables lead to a greater intention to adopt BIM technology.Originality/Value: The study indicates that improving the BIM adoption status in the Iranian construction industry may be possible by strengthening individual and behavioural dimensions to further BIM adoption.…”
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Gene by Sex Interaction for Measures of Obesity in the Framingham Heart Study by Ashlee M. Benjamin, Sunil Suchindran, Kaela Pearce, Jennifer Rowell, Lillian F. Lien, John R. Guyton, Jeanette J. McCarthy

“…Genotype data from individuals in the Framingham Heart Study Offspring cohort were analyzed across five exams. …”
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Future anxiety, depression and stress among undergraduate students: psychological flexibility and emotion regulation as mediators by Gülçin Güler Öztekin, Juan Gómez-Salgado, Juan Gómez-Salgado, Murat Yıldırım, Murat Yıldırım

“…The associations between future anxiety, depression and stress were mediated by psychological flexibility, cognitive reappraisal and expressive suppression.DiscussionThis study deepened our understanding of the possible mechanisms of depression and stress. For individuals suffering from future anxiety, psychological flexibility and emotion regulation may be a coping strategy that leads individuals to less depression and stress. …”
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T Cell Reactivity against Mycolyl Transferase Antigen 85 of M. tuberculosis in HIV-TB Coinfected Subjects and in AIDS Patients Suffering from Tuberculosis and Nontuberculous Mycoba... by Pascal Launois, Annie Drowart, Eliane Bourreau, Pierre Couppie, Claire-Michèle Farber, Jean-Paul Van Vooren, Kris Huygen

“…Here, we have analyzed T cell reactivity against PPD and Ag85 in HIV-infected individuals, without or with clinical symptoms of tuberculosis, and in AIDS patients with disease caused by nontuberculous mycobacteria. …”
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The Effects of the Social Hierarchy Destabilization on the Foraging Activity of Eusocial Wasp Mischocyttarus cerberus styx Richards, 1940 (Hymenoptera: Vespidae: Polistinae) by Vanderlei Conceição Costa Filho, Sulene Noriko Shima, Ivan Cesar Desuó, André Sunao Nishiuchi Murakami

“…They form small colonies (rarely more than few tens of individuals); castes are morphologically undifferentiated and determined behaviorally by agonistic interactions. …”
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Multi-level encoding of reward, effort, and choice across the frontal cortex and basal ganglia during cost-benefit decision-making by Oliver Härmson, Isaac Grennan, Brook Perry, Robert Toth, Colin G. McNamara, Timothy Denison, Hayriye Cagnan, Sanjay G. Manohar, Mark E. Walton, Andrew Sharott

“…Coactive cell assemblies, ensembles of neurons that repeatedly coactivated within short time windows (<25 ms), represented the same decision variables despite the members often having diverse individual coding properties. Together, these findings demonstrate a multi-level encoding structure for cost-benefit computations where individual neurons are coordinated into larger assemblies that can represent task variables independently of their constituent components.…”
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Exploring the melodies of opportunity: do nepo babies pursue music out of genuine passion or is it a matter of engaging in musicpreneurship? by Eugine Tafadzwa Maziriri, Brain Mabuyana, Brighton Nyagadza, Mufaro Dzingirai, Tafadzwa C. Maramura

“…Purpose – In recent years, a number of privileged individuals have entered the music industry in Zimbabwe, either as performers or entrepreneurs. …”
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