Reliability of Schirmer and Phenol Red Thread test value on dry eye patients by Urvashni Nirghin, Tharuna Govender, Yeshalya Hirachund, Rorisang Mosololi, Hlengiwe Nxumalo, Sumaya Patel, Philani Zwane, Khathutshelo P. Mashige

“…Contribution: The ST and the PRT provide consistent and reproducible results on dry eye patients when conducted on the same individuals at different time points.…”
Get full text

Diploid aposporous sunflower forms triploid BIII progeny displaying increased apospory levels and non-random genetic mutations by Silvina Pessino, Graciela Nestares, Marta B. Bianchi, Iara Katzaroff, Lucía Amato, Marika Bocchini, Gianpiero Marconi, Emidio Albertini, Ana C. Ochogavía

“…A segregant F2 progeny, comprising diploid and triploid individuals, was generated by crossing Rf975 with HA89, a genetically divergent sexual diploid. …”
Get full text

Studying dynamic changes in body mass and mass of internal organs in laboratory rats experimentally infected with bovine leukosis virus by E. S. Krasnikova, R. V. Radionov, A. V. Krasnikov, A. Yu. Svetozarova

“…In this regard, it is of interest to analyze disorders caused by these dysfunctions; the disorders are demonstrated by changed morphometric characteristics of both the body and individual organs. The aim of the research was to study dynamic changes in body mass and mass of internal organs in laboratory rats experimentally infected with BLV. …”
Get full text

MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing by Robinson Vidva, Mir Abbas Raza, Jaswant Prabhakaran, Ayesha Sheikh, Alaina Sharp, Hayden Ott, Amelia Moore, Christopher Fleisher, Hailey Netherton, Evan Goldstein, Pothitos M. Pitychoutis, Tam V. Nguyen, Aaron Sathyanesan

“…Using MyVivarium, lab members can collaboratively track individual animals within a database. Physical identities of cages map onto the database using QR codes, enabling quick and easy record-keeping on mobile devices. …”
Get full text

A Nonsynonymous Single-nucleotide Polymorphism in SLC24A5 Regulates Feather Pigment Deposition in Chinese Yellow Quail by Xiaohui Zhang, Fanghu Wu, Yanxia Qi, Yuanyuan Shang, Lingyun Fan, Yifei Wang

“…The mutant residue was predicted to be located inside the eighth transmembrane helix of the SLC24A5 protein, which is primarily responsible for recognizing Na+/Ca2+ ions. Mutant individuals had significantly lower total melanin content in the feathers and tyrosinase activity in dorsal skin, in spite of no significant difference in SLC24A5 mRNA expression in the same tissues. …”
Get full text

Anatomical alterations: biparietal thinning in antiquity. Review of published cases and a new case by Nicol Rossetti, Roberta Fusco, Arianna Vanni, Francesca Garanzini, Alessandra Mazzucchi, Marta Licata

“…Our analysis of the skeletal remains of an old adult female individual revealed clear indicators of biparietal thinning. …”
Get full text

Production of all-triploid derived from gynogenetic homologous diploid crucian carp (♀) × diploid red crucian carp (♂) by Chongqing Wang, Yan Tang, Xiang Luo, Yuxin Zhang, Yue Zhou, Qingwen Xiao, Zhengkun Liu, Xinyi Deng, Xu Huang, Xidan Xu, Xiaowei Xu, Kun Zhang, Qinbo Qin, Shaojun Liu

“…The genetic characteristics of 5S rDNA in 3nRR individuals and their parental counterparts, as well as the measurable and countable traits, were explored. …”
Get full text

Bicyclic peptide-enhanced covalent inhibitor of SARS-CoV-2 3CL protease by Qian Wang, Yanhui Wang, Jian Li, Hong Liu, Shiyu Chen

“…Optimization through medicinal chemistry strategies not only improved the potency of the peptides but also revealed residue preferences at individual positions of the bicyclic peptide inhibitors. …”
Get full text

Constraints on the Variation of the Fine-structure Constant at 3 < z < 10 with JWST Emission-line Galaxies by Linhua Jiang, Shuqi Fu, Feige Wang, Sarah E. I. Bosman, Zheng Cai, Hyunsung D. Jun, Zhiwei Pan, Fengwu Sun, Jinyi Yang, Huanian Zhang

“…We divide our sample into six subsamples based on redshift and calculate the relative variation Δ α / α for the individual subsamples. The calculated Δ α / α values are consistent with zero within 1 σ at all redshifts, suggesting no time variation in α above a level of (1–2) × 10 ^−4 (1 σ ) in the past 13.2 billion yr. …”
Get full text

PI3Kδ inhibitor linperlisib combined with gemcitabine and oxaliplatin for relapsed or refractory diffuse large B-cell lymphoma: a multicenter, single-arm phase Ib/II trial by Peng Sun, Hong Cen, Haiyan Yang, Rui Huang, Zhen Cai, Xuekui Gu, Hanying Bao, Zusheng Xu, Zuhong Xu, Zhi-Ming Li

“…Methods This was a multicenter, phase Ib/II clinical study conducted across six sites in China, enrolling 39 individuals with histologically confirmed R/R DLBCL. …”
Get full text

Leveraging LLMs and wearables to provide personalized recommendations for enhancing student well-being and academic performance through a proof of concept by Arfan Ahmed, Sarah Aziz, Alaa Abd-alrazaq, Rawan AlSaad, Javaid Sheikh

“…Personalized recommendations based on individual data hold promise. This study explores the potential of Large Language Models (LLMs) to generate personalized recommendations for 12 high school students to enhance their well-being and academic performance. …”
Get full text

Impact of trapping on tritium self-sufficiency and tritium inventories in fusion power plant fuel cycles by Samuele Meschini, Rémi Delaporte-Mathurin, George R. Tynan, Sara E. Ferry

“…However, detailed analysis of individual components reveals that substantial amounts of tritium can be trapped within the first wall, divertors, and breeding blanket systems, suggesting that tritium trapping may significantly influence the FPP ability to achieve self-sufficiency. …”
Get full text

Filtration Performance of Layering Masks and Face Coverings and the Reusability of Cotton Masks after Repeated Washing and Drying by Sumit Sankhyan, Karen N. Heinselman, Peter N. Ciesielski, Teresa Barnes, Michael E. Himmel, Hannah Teed, Sameer Patel, Marina E. Vance

“…In most of these combinations, the filtration efficiency improved by ~25% for particles 0.3–1 µm in diameter without any substantial change in the filter quality factor when compared to the highest of the individual mask results. To investigate the reusability of cotton cloth masks, 2-layer cotton fabric sample coupons were machine washed and dried for 52 cycles leading to an increase in inhalation resistance (~20 Pa) without affecting size-resolved filtration efficiency. …”
Get full text

SNP-array profiling data from breast cancer patients and healthy women's blood DNA samplesGEO by Rafika Indah Paramita, Sonar Soni Panigoro, Fadilah Fadilah, Septelia Inawati Wanandi, Noorwati Sutandyo

“…After the conclusion of the quality control procedure, 72 individuals and a dataset consisting of 424,285 genetic variants were selected for further analysis. …”
Get full text

Molecular imprinted polymer-based potentiometric approach for the determination of carvedilol and ivabradine hydrochloride in dosage form, spiked human plasma and in presence of th... by Nermine V. Fares, Haitham A. El Fiky, Dina A. Ahmed, Maha F. Abd El Ghany, Amr M. Badawey, Mahmoud A. Tantawy

“…MIPs’ graved cavities serve as artificial host-tailored receptors that are able to recognize and bind to individual drugs. Carvedilol MIP-based sensor showed Nernstian slope of 55.30 mV/decade while the corresponding value for ivabradine one was 55.50 mV/decade. …”
Get full text

Modeling and Planning a Transmission Network Expansion System in a Regulated Electricity Market by Considering Demand-Side Management via a Developed Fuzzy-Salp Optimization Algori... by Yuying Zhang, Lei Xu, Ji Li, Long Zhang, Zhi Yuan

“…This is widely accepted: increasing the presence and participation of consumers in DR programs in the electricity market will benefit not only individual consumers but also the whole consumer community. …”
Get full text

Analysis of Method Performance for Quantitative Assessment of Listeria monocytogenes in Queso Fresco Cheese by Neha Singh, Ravinder Reddy, Karina Hettwer, Kirstin Frost, Matthew Kmet, Steffen Uhlig

“…Statistical analysis was conducted to analyze test sample preparation and evaluate the performance of the quantitative method by utilizing participant’s data. Although individually inoculated, the samples were considered replicates based on the standard deviation values obtained from the Q/Hampel method. …”
Get full text

Relationship between personality traits and spontaneous coronary artery dissection risk: evidence from Mendelian randomization by Kun Zheng, Kun Zheng, Mengdi Wu, Junhua Wang, Junhua Wang, Jinjin Sun, Yuqian Li, Peng Wang, Zhiyue Zhang, Xiuming Pan, Yifeng Yang, Tianqi Li, Yujie Guo

“…BackgroundSpontaneous coronary artery dissection (SCAD) significantly contributes to myocardial infarction among young individuals. Despite the elusive nature of its etiology, empirical evidence indicates a substantial correlation between sociopsychological factors and the disorder. …”
Get full text

Sample size calculations based on day-to-day variability of stress biomarkers in persons with dementia and their family caregivers by Azita Emami, Jeehye Jun, Gabriella Engström, Lars Berglund, Töres Theorell

“…Introduction: Accurate estimates of intra-individual variability are necessary for proper design of clinical trials and epidemiological studies where the stress biomarkers cortisol and dehydroepiandrosterone sulfate (DHEA-S) are measured for dyads of persons with dementia (PWDs) and their family caregivers (FCGs). …”
Get full text

A soft tick vector of Babesia sp. YLG in Yellow-legged gull (Larus michahellis) nests by Bonsergent, Claire, Vittecoq, Marion, Leray, Carole, Jouglin, Maggy, Buysse, Marie, McCoy, Karen D., Malandrin, Laurence

“…We collected ticks over four years, maintained certain individuals through moulting or oviposition, and dissected fresh ticks to isolate different organs and test for the presence of the parasite using molecular assays. …”
Get full text