At-Home Immersive Virtual Reality Exergames to Reduce Cardiometabolic Risk Among Office Workers: Protocol for a Randomized Controlled Trial by Jing Zhao, Akitomo Yasunaga, Andrew T Kaczynski, Hyuntae Park, Yufeng Luo, Jiuling Li, Ai Shibata, Kaori Ishii, Shohei Yano, Koichiro Oka, Mohammad Javad Koohsari

“…The use of virtual reality (VR) exergames may offer a potential solution to the problem of increasing noncommunicable disease prevalence, as it can help individuals increase their physical activity levels while providing a more immersive experience. …”
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The Effectiveness of pen‒culture construction for cultivation of sea cucumber by Pitjont Tomatala, Petrus Paulus Letsoin, Evangelin Martha Yulia Kadmaer

“…The two of cultivated containers tested were a conventional pen‒culture (treatment A) and engineered pen‒culture (treatment B). A total of 30 individuals sea cucumber seeds sized 4‒6 cm were released at each pen‒culture. …”
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The Effect of using the Smartphone in the Workplace on Job Engagement and Job Burnout: Investigation of Mediational Role of Stress by Somayeh Naghdi Zarrin, Neda Mohammad Esmaeili

“…Objective In today's rapidly evolving digital era, the prevalence of smartphone usage among individuals in various contexts, including both social and professional environments, is witnessing a remarkable increase. …”
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Impact of interpregnancy weight change on the risk of gestational diabetes mellitus during a second pregnancy in Chinese population: a retrospective cohort study by Ying Wang, Juan Yang, Chang Xu, Yuzhen Liu, Ao Yang, Shilin Zhong

“…IPWC < −1 kg/m² was not significantly associated with s-GDM either in the overall analysis or in the stratified analysis (p>0.05).Conclusion An IPWC of 3 kg/m² or higher may increase the risk of s-GDM, particularly among women with an IPI of less than 36 months, those under 35 years old, individuals without diabetes, or those with normal weight during their first pregnancy. …”
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Ultrasound-based radiomics and clinical factors-based nomogram for early intracranial hypertension detection in patients with decompressive craniotomy by Zunfeng Fu, Lin Peng, Laicai Guo, Chao Qin, Yanhong Yu, Jiajun Zhang, Yan Liu

“…It shows promise for enhancing non-invasive ICP monitoring and supporting individualized therapeutic strategies.…”
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Examining the Effect of Prototypical Leadership Style on Leader Effectiveness: Mediating role of Perceived Integrity and Moderating Role of Leader-leader Exchange by Elham Ebrahimi, SHabnam Zarjou

“…A statistical sample of 293 individuals was selected based on the tests used and G-Power software. …”
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Dihydrotanshinone I enhanced BRAF mutant melanoma treatment efficacy by inhibiting the STAT3/SOX2 signaling pathway by Xing Luo, Yi Duan, Jinwei He, CongGai Huang, Jun Liu, Yifan Liu, Mengdei Xu, Qiong Dai, Zhihui Yang

“…BackgroundThe Food and Drug Administration has approved the Serine/threonine-protein kinase B-raf (BRAF) inhibitor and Mitogen-activated extracellular signal-regulated kinase (MEK) inhibitor combo as the first-line treatment for individuals with metastatic melanoma, although the majority of these patients exhibit primary or secondary drug resistance in the clinic. …”
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Medication patterns and potentially inappropriate medication in patients with metastatic breast cancer: results of the BRE-BY-MED study by Lilly Sophia Brandstetter, Anna Grau, Peter U. Heuschmann, Max Müller-Reiter, Jessica Salmen, Stefan Störk, Achim Wöckel, Jens-Peter Reese

“…Methods Between July 2022 and February 2024 individuals with advanced or mBC, aged ≥ 18 years, living in Bavaria, and who gave written informed consent, were included in the BRE-BY-MED “Breast Cancer Care in Bavaria for Patients with Metastatic Disease” cohort study (DRKS00026601). …”
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Correlation Between the Ratio of Uric Acid to High-Density Lipoprotein Cholesterol (UHR) and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus:A Cross-Sectional Study by Wang L, Liu L, Luo H, Wu Y, Zhu L

“…We gathered demographic and clinical data, calculated UHR, and explored its correlation with DR development.Outcomes: Individuals diagnosed with diabetic retinopathy (DR) exhibited a markedly elevated uric acid to high-density lipoprotein cholesterol (UHR) ratio when contrasted with those without DR (NDR), achieving statistical significance with a P-value below 0.001. …”
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Providing a General Model for the Successful Implementation of Digital Transformation in Organizations by Haidar Ahmadi, Najme Parsaei, Seyyed Hamed Hashemi, Hamidreza Nematollahi

“…Data collection was primarily conducted through semi-structured interviews with 15 individuals until theoretical saturation was achieved. …”
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Screening of West Siberian patients with primary congenital glaucoma for CYP1B1 gene mutations by D. E. Ivanoshchuk, S. V. Mikhailova, O. G. Fenkova, E. V. Shakhtshneider, A. Z. Fursova, I. V. Bychkov, M. I. Voevoda

“…None of the detected mutations were found in the control sample of ophthalmologically examined individuals without PCG (100 people). Variants R444* (rs377049098) and R444Q (rs72549376) were not found in the general population sample either (576 randomly selected West Siberia residents). …”
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5,10-methylenetetrahydrofolate reductase C677T gene polymorphism as a risk factor for premature coronary artery disease in patients with type 2 diabetes mellitus by Nisreen O. Mohammed, Ibtisam A. Ali, Bahaelddin K. Elamin, Bakri Osman Saeed

“…Plasma homocysteine levels were higher in individuals with TT genotype than those with CT or CC genotypes in patients with PCAD (16.2 + 5.3, 14.3 + 5.7 and 12.9 + 5.02 µmol/L, p=0.017). …”
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Risk Factors and Pharmacological Interventions Impacting Cerebrovascular Ischemic Events in Giant Cell Arteritis: A Narrative Review by Muhammad Osama Siddiqui, Mohammad Ali Syed, Ayaan Ahmed Qureshi, Mustafa Hussain Imam, Jatin Motwani, Verkha Kumari, Arooba Siddiqui, Noor Ul Ain, Mohammed Hammad Jaber

“…ABSTRACT Introduction Giant cell arteritis (GCA) is a common vasculitis predominantly affecting larger vessels, especially in individuals aged 70–79. Cerebrovascular ischemic events (CIE), such as stroke and transient ischemic attacks, are serious but rare complications of GCA, with a pooled prevalence of 4%. …”
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Effects of Electrical Stimulation on Activation of Mirror Neuron Network in Healthy Adults during Motor Execution and Imitation: An fNIRS Study by Yao Cui, Fang Cong, Fu-Biao Huang, Ming Zeng, Jun Wang

“…Methods: We recruited healthy individuals and assigned them randomly to the control group (CG) or experiment group (EG). …”
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Prevalence, cessation, and geographical variation of smoking among middle-aged and elderly adults in China: A population-based study by Qingjia Zeng, Chongyang Zhang, Feiyu Su, Yanli Wan, Wen-jun Tu, Hongpu Hu

“…Conclusions This comprehensive study emphasizes the profound impact of smoking on health in Chinese adults, indicating the critical need for tailored cessation programs, particularly for middle-aged individuals, men, rural residents, and those with lower educational backgrounds.…”
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Joint association of systemic immune-inflammation index and phenotypic age acceleration with chronic respiratory disease: a cross-sectional study by Yuan Zhan, Ruonan Yang, Jie Feng, Genlong Bai, Xiangyun Shi, Jiaheng Zhang, Jingbo Zhang

“…Furthermore, the joint-indexes analysis revealed that compared to individuals with lower SII and PhenoAgeAccel, those with higher SII and PhenoAgeAccel exhibited remarkably stronger associations with CRD (adjusted OR [aOR], 1.56; 95% CI, 1.31–1.85; P < 0.001), chronic obstructive pulmonary disease (aOR, 1.56; 95% CI, 1.22-2.00; P = 0.001) and asthma (aOR, 1.40; 95% CI, 1.16–1.70; P = 0.001), which were predominant among those aged above 40 years, females and smokers. …”
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Does digital, multimedia information increase recruitment and retention in a children’s wrist fracture treatment trial, and what do people think of it? A randomised controlled Stud... by Jacqueline M Martin-Kerry, Peter Knapp, Steven Higgins, Rebecca Sheridan, Juul Achten, Duncan Appelbe, Louise Spoors, Thirimon Moe-Byrne, Daniel Perry, Jenny Roche

“…Secondary outcomes were Decision-Making Questionnaire (nine Likert items, analysed summatively and individually), three ‘free text’ questions (deriving subjective evaluations) and trial retention.Results MMI produced a small, not statistically significant increase in recruitment: 475 (69.8%) participants were recruited from the MMI group; 484 (66.5%) from the PIS group (OR=1.35; 95% CI 0.76 to 2.40, p=0.31). …”
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Preterm preeclampsia screening and prevention: a comprehensive approach to implementation in a real-world setting by Stefania Ronzoni, Shamim Rashid, Aimee Santoro, Elad Mei-Dan, Jon Barrett, Nanette Okun, Tianhua Huang

“…Methods A prospective cohort study involved pregnant individuals undergoing nuchal translucency scans between 11 and 14 weeks. …”
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Dataset of SARS-CoV-2 spike protein receptor binding domain variants in complex with antigen-binding fragments targeting COVID-19 vaccine-referenced variantsModel Archive by Ferdinando Spagnolo, Florigio Lista, Claudia Curcio

“…For each variant, the homology-modeled RBDs were complexed with the Fab fragments from 8GPY, 8H7Z, and 8XE9 by grafting them onto the RBDs, followed by energy minimization, both individually and in combination. This process resulted in a comprehensive dataset of RBD-Fab complexes, suitable for comparative analysis and further investigations.Binding affinities between the RBD-Fab pairs were calculated using the Prime MM-GBSA tool (VSGB solvation model and OPLS4 force field), enabling the ranking of antigen-antibody interactions. …”
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Informal Caregivers Connecting on the Web: Content Analysis of Posts on Discussion Forums by Michelle L Foster, Chinenye Egwuonwu, Erin Vernon, Mohammad Alarifi, M Courtney Hughes

“…Researchers extracted the first 6 responses to the first 20 questions and comments to appear posted by the informal caregivers in each of the 5 forums, removing any individually identifying information. We used a codebook thematic analysis approach to examine the data with Dedoose (SocioCultural Research Consultants). …”
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