Knockdown of PDPN in astrocytes reduces hippocampal inflammation in T2DM mice by Xiaohang Wang, Xiaohang Wang, Xiaohang Wang, Qianqian Wang, Zhensheng Cai, Chengming Ni, Huan Wang, Hui Liu, Yusong Zhao, Jinbang Wang, Subo Liu, Xueying Wang

“…AimsIndividuals with type 2 diabetes mellitus (T2DM) are at-risk for developing vascular dementia (VaD). …”
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A20 as a Potential Therapeutic Target for COVID‐19 by Yongyao Wu, Lilan He, Rong Li, Jiuxuan Li, Qing Zhao, Bin Shao

“…We also downloaded single‐cell RNA‐seq data sets from healthy individuals and patients with varying severities of COVID‐19 from the NCBI GEO database to further dissect A20's regulatory mechanisms of these intricate cytokine pathways that are closely associated with SARS‐CoV‐2 infection. …”
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Effects of the physical form of starter feed on the intake, performance, and health of female Holstein calves by Í.R.R. Castro, G.B.C. Leite, I.F. Carrari, L.N.C. Silva, J.C.C. Chagas, D.D. More, M.I. Marcondes

“…Twenty-four female Holstein calves (5-d-old; 40.4 ± 3.86 kg BW; mean ± SD) were used in a completely randomized block design. Calves were individually housed and randomly assigned to the treatments (n = 12 calves/treatment): (1) textured starter feed (TSF, a mix of pelleted ingredients and whole-kernel corn) and (2) pelleted starter feed (PSF). …”
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Investigating the feasibility of developing a collective action for biological control of fall armyworm among smallholder farmers in rural communities of Zambia by Léna Durocher-Granger, Sara Fiorito, Sibajene Kambanja Mudenda, Milimo Mildred Chiboola, Monica K. Kansiime, David Ludwig, Cees Leeuwis

“…Abstract Background Fall armyworm, Spodoptera frugiperda, an alien invasive pest from the Americas, was detected in Zambia late 2016 and since has caused significant losses on maize threatening livelihood and food security. Individually, farmers continue to rely on synthetic pesticides, a reactive measure to manage new invasive insect pests, posing risks to human health, the environment and biodiversity. …”
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Depth-Dependent Cellular Response from Dental Bulk-Fill Resins in Human Dental Pulp Stem Cells by Su-Min Lee, Soo-Youn Kim, Jae-Heon Kim, Soo-Kyung Jun, Hae-Won Kim, Jung-Hwan Lee, Hae-Hyoung Lee

“…Three bulk-fill composite resins (SDR, Venus bulk-fill (VBF), and Beautifil Bulk Flowable (BBF)) and a conventional flowable composite resin (Filtek Z350 XT flowable restorative (ZFF)) were individually filled into a cylindrical hole (h=2 mm, Ф=10 mm), and three compartments (total ~6 mm of height) were combined as a single assembly for light curing. …”
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Comparison of fracture risk calculators in elderly fallers: a hospital-based cross-sectional study by Sophia von Widekind, Georgi Todorov, Susan Brook, Nicole Quah Qin Xian, Bernard Freudenthal, Alexander N Comninos

“…However, they differ considerably in their inputs and may therefore provide contrasting risk estimations in certain individuals. In this study, we compare these risk calculators in a high-risk cohort of elderly patients admitted to hospital with falls.Design Hospital-based cross-sectional study.Setting Secondary care, London, UK.Participants Data from 120 consecutive elderly patients who had falls presenting to a single hospital over 4 months were collected. 10-year major and hip fracture risks were calculated using FRAX, QFracture and Garvan. 1-year major and hip fracture risks from QFracture were assessed against prospective incidence of fracture.Results Median 10-year major fracture risk was: FRAX 19.5%, QFracture 26.0%, Garvan 32.5%. …”
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Efficacy of rituximab as second-line therapy for autoimmune encephalitis: A systematic review and meta-analysis by Lin-ming Zhang, Xuan-lin Xing, Bing-ran Zhang, Qiu-juan Zhang, Yan-lin Zhu, Shu-ji Gao, Ming-wei Liu

“…Background: Approximately 20%–50 % of individuals with autoimmune encephalitis (AE) demonstrate suboptimal responses to first-line therapies, leading to persistent neurological deficits and the need for second-line interventions. …”
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Varying circumstances surrounding opioid toxicity deaths across ethno-racial groups in Ontario, Canada: a population-based descriptive cross-sectional study by Tara Gomes, Mina Tadrous, Sophie A Kitchen, Frank Crichlow, Tonya J Campbell, Cynthia Damba, Colin H Johnson, Ashley Smoke

“…Accordingly, we sought to describe and compare characteristics and circumstances of opioid toxicity deaths across ethno-racial groups.Methods We conducted a population-based, descriptive cross-sectional study of all individuals who died of accidental opioid toxicity in Ontario, Canada between 1 July 2017 and 30 June 2021. …”
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Menopause and obstructive sleep apnea: revealing an independent mediating role of visceral fat beyond body mass index by Yuhan Wang, Hailing Liu, Beini Zhou, Wuriliga Yue, Mengcan Wang, Ke Hu

“…Results The analysis comprised 1459 individuals from NHANES, consisting of 1188 premenopausal and 271 postmenopausal women. …”
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Citizen engagement in public food procurement, a novel choose-your-own-adventure canteen campaign case study by Luke John Schafer, Anna Gundorph, Carla Mingolla, Christian Bugge Henriksen, Marin Lysak, Reni Todorova Boncheva, Maarten Crivits

“…A further 24% expressed interest and 10% reached the third level by being involved in workshops. Nine individuals showed signs of reaching the forth and highest-level, empowerment, by expressing their interest in directly improving or collaborating future iterations of the canteen campaign. …”
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Implementing a Care Model for Bedridden Stroke Survivors: A Qualitative Study in Northeastern Thailand by Panpanit L, Jongudomkarn D, Doungmungkorn A, Boontoch K, Neelasmith S, Manorat M, Maneerat T

“…Its adoption by local administrative organizations could provide ongoing support, offering a scalable solution for improving the care of bedridden individuals both in Thailand and globally.Keywords: the KKU Bedridden Care Model, community caregivers, family caregivers, stroke survivors, long-term care, Northeastern Thailand…”
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Estimation of cause-specific mortality in Rakai, Uganda, using verbal autopsy 1999-2019 by Dorean Nabukalu, Júlia Almeida Calazans, Milly Marston, Clara Calvert, Hadijja Nakawooya, Brendah Nansereko, Robert Sekubugu, Gertrude Nakigozi, David Serwadda, Nelson Sewankambo, Godfrey Kigozi, Ronald H Gray, Fred Nalugoda, Fredrick Makumbi, Tom Lutalo, Jim Todd

“…The average number of years lived in adulthood increased in people living with HIV and decreased in HIV-negative individuals between 2000 and 2019. Communicable diseases, primarily HIV and Malaria, had the biggest decreases, which improved the average number of years lived by approximately extra 12 years of life in females and 6 years in males. …”
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TESTING POTATO COLLECTION SAMPLES FOR THE PRESENCE OF GENES FOR RESISTANCE TO PHYTOPATHOGENS BY MEANS OF DNA MARKERS by A. B. Saynakova, M. S. Romanova, S. N. Krasnikov, O. V. Litvinchuk, Ya. I. Alekseev, A. V. Nikulin, E. V. Terentjeva

“…The sample included two varieties, three populations produced by self-pollination of the Ideal variety, and 35 individually selected potato hybrids. As a result, we identified marker NL25 (Sen1) in 19 samples; marker PVX (Rx) in 13 samples; marker RYSC3312 (Ryadg) in 10 samples; marker YES3-3A341 (Rysto) in 5 samples; markers TG 689141, 57R450, N195337 (H1) in 12 samples; marker Gro1-4-1602 (Gro1-4) in 6 samples; marker Gpa2-2452 (Gpa2) in 13 samples. …”
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Anxiety and depression in primary knee osteoarthritis patients: are they related to clinical features and radiographic changes? by Yasmin A. Abd Elhamid, Ghada S. Elazkalany, Marwa H. Niazy, Angie Y. Afifi

“…Material and methods Fifty patients fulfilling primary knee OA classification criteria were recruited for the study, and 50 age- and sex-matched healthy individuals served as a control group. Medical history was taken, clinical examination was done, and pain intensity was assessed using the Visual Analogue Scale. …”
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Evaluating Tech Neck: A Pilot Study Using a Self-Developed Questionnaire on Symptoms, Posture, and Preventive Measures by Brigitte Osser, Csongor Toth, Carmen Delia Nistor-Cseppento, Gyongyi Osser, Caius Calin Miuța, Iosif Ilia, Diana Carina Iovanovici, Cristina Aur, Laura Ioana Bondar

“…Background/Objectives: Musculoskeletal symptoms, such as neck pain, back pain, and eye strain, are prevalent in modern work environments, particularly among individuals engaged in prolonged sitting and repetitive tasks. …”
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Nutritional Profiles and Factors Associated with the Intake of Certain Food Types in Patients Undergoing Maxillofacial Prosthetic Rehabilitation: A Cross-Sectional Study by Nehasha Pradhan, Mai Murase, Masako Akiyama, Hiroko Tani, Yuka I. Sumita, Noriyuki Wakabayashi

“…Additionally, the importance of a multidisciplinary approach to nutritional care for these individuals is underscored.…”
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Effect of a Hemodialysis Session on Markers of Inflammation and Endotoxin by Shyam Dheda, David A Vesey, Carmel Hawley, David W Johnson, Magid Fahim

“…In this study, serum concentrations of endotoxin and inflammatory biomarkers, including high-sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6), interleukin-1β (IL1β), ferritin and tumor necrosis factor (TNF), were measured in 30 adults receiving HD and 10 healthy individuals without kidney disease. In people receiving HD, samples were collected immediately before dialysis (preHD), after dialysis (postHD), and 48 hours after (postHD48hrs). …”
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Prevalence and Determinants of Hypertension Awareness, Treatment, and Control in Botswana: A Nationally Representative Population-Based Survey by Neo M. Tapela, Lei Clifton, Gontse Tshisimogo, Moagi Gaborone, Tebogo Madidimalo, Virginia Letsatsi, Tiny Masupe, Mosepele Mosepele, Joseph Makhema, Shahin Lockman, David J. Hunter

“…Males were less likely to be aware (aOR 0.62, 0.41–0.94) or controlled (aOR 0.36, 0.16–0.83). Obese individuals were more likely to be treated (aOR 2.17, 1.12–4.22), yet less likely to be controlled (aOR 0.32, 0.15–0.66). …”
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Ratio-dependent competitions between a Wolbachia-uninfected bisexual strain and Wolbachia-infected thelytokous strain of the egg parasitoid, Trichogramma dendrolimi Matsumura (Hyme... by Qian-Jin Dong, Yue He, Yu-Zhe Dong, Wu-Nan Che, Jin-Cheng Zhou, Hui Dong

“…Mutual interference between individuals was not affected by competition types. Females of the Inter-Td group exhibited a higher probability of superparasitism than those of the Intra-TdB group or Inter-Td group. …”
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The growth and physiological responses of tambaqui Colossoma macropomum fed on the high dose of clove oil-supplemented diet by Andi Tiara Eka Diana Puteri, Dedi Jusadi, Sri Nuryati

“…Sebanyak 25 ekor ikan bawal dengan bobot individu awal 7,62 ± 0,44 g dipelihara pada 15 akuarium selama 45 hari. …”
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