Psychosocial and pharmacologic interventions for problematic methamphetamine use: Findings from a scoping review of the literature. by Mona Hersi, Kim Corace, Candyce Hamel, Leila Esmaeilisaraji, Danielle Rice, Nicole Dryburgh, Becky Skidmore, Gary Garber, Amy Porath, Melanie Willows, Paul MacPherson, Beth Sproule, Jorge Flores-Aranda, Chandlee Dickey, Brian Hutton

“…Screening was performed following a two-stage process, leveraging artificial intelligence to increase efficiency of title and abstract screening. Studies involving individuals who use methamphetamine, including key subgroups (e.g. those with mental health comorbidities; adolescents/youths; gay, bisexual, and other men who have sex with men) were sought. …”
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Molecular characterization of a rare TP63 variant associated with split-hand/split-foot malformation 4 and incomplete penetrance: disruption of the p63-Dlx signaling pathway by Jianlong Zhuang, Yanqing Li, Yu’e Chen, Hegan Zhang, Shufen Liu, Manman Hu, Chunnuan Chen

“…Conclusion This study identifies, for the first time, the TP63 gene variant c.956G > A (p.Arg319His) as a causative factor for SHFM4 in Chinese individuals with incomplete penetrance. In addition, we hypothesize that the p.Arg319His variant functions as a gain-of-function variant, leading to the upregulation of cell adhesion target genes. …”
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Prevalence of diabetic retinopathy and its associated factors among adults in East African countries: A systematic review and meta-analysis. by Habtamu Wagnew Abuhay, Tigabu Kidie Tesfie, Meron Asmamaw Alemayehu, Muluken Chanie Agimas, Getaneh Awoke Yismaw, Gebrie Getu Alemu, Nebiyu Mekonnen Derseh, Bantie Getnet Yirsaw

“…<h4>Conclusions</h4>The prevalence of DR in East Africa was high, with more than one in four individuals with diabetes developing DR. Besides, advanced age, higher body mass index, and elevated hemoglobin A1c levels were significant factors associated with increased DR prevalence. …”
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Prevalence, risk factors, and cardiovascular disease outcomes associated with persistent blood pressure control: The Jackson Heart Study. by Gabriel S Tajeu, Calvin L Colvin, Shakia T Hardy, Adam P Bress, Bamba Gaye, Byron C Jaeger, Gbenga Ogedegbe, Swati Sakhuja, Mario Sims, Daichi Shimbo, Emily C O'Brien, Tanya M Spruill, Paul Muntner

“…<h4>Background</h4>Maintaining blood pressure (BP) control over time may contribute to lower risk for cardiovascular disease (CVD) among individuals who are taking antihypertensive medication.…”
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Comparison of SNP Genotypes Related to Proliferative Vitreoretinopathy (PVR) across Slovenian and European Subpopulations by Xhevat Lumi, Mateja M. Jelen, Daša Jevšinek Skok, Emanuela Boštjančič, Metka Ravnik-Glavač, Marko Hawlina, Damjan Glavač

“…Genotype distributions of 42 SNPs among 96 Slovenian healthy controls were investigated and compared to genotype frequencies in 503 European individuals (Ensembl database) and their subpopulations. …”
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Retrospective Observational Study on the Characteristics of Pain and Associated Factors of Breakthrough Pain in Advanced Cancer Patients by Rongrong Fan, Xuying Li, Siyu Yang, Xiaofan Bu, Yongyi Chen, Ying Wang, Cuiling Qiu

“…BTP should be managed individually, especially the invisible pain among aged patients. …”
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Association of physical and sexual assault with mortality in two British birth cohorts by Jayati Das-Munshi, Ioannis Bakolis, William Lee, Vishal Bhavsar, James H MacCabe

“…The birth cohorts were analysed separately, and together estimating interaction between exposure and cohort year.Results Results were based on 353 deaths in 19 725 individuals. Based on multiply imputed data, the fully adjusted estimate for assault on mortality was 1.72 (95% CI 1.22 to 2.42) in the combined cohorts, 1.53 (95% CI 0.97 to 2.40) in the 1958 birth cohort and 2.05 (95% CI 1.20 to 1.50) in the 1970 birth cohort. …”
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Impact of remnant cholesterol on acute ischemic stroke prognosis: a nationwide cohort analysis stratified by non-alcoholic fatty liver disease status by Sili Jiang, Aoming Jin, Aoming Jin, Wenli Xing, Jing Jing, Jing Jing

“…Interaction effect analysis was performed to investigate how NAFLD modifies the relationship between RC and prognosis.ResultsAmong the 7, 234 participants, the mean age was 62.96 ± 11.44 years and 4,572 (63.2%) were male individuals. Compared to the lowest quartile of RC (Q1), the highest quartile of the RC (Q4) was associated with a lower risk of poor functional outcomes (OR: 0.98, 95% CI: 0.96–1.00). …”
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Shoulder Isokinetic Strength Balance Ratio in Overhead Athletes: A Cross-Sectional Study by Valentine Zimermann Vargas, Caroline Motta, Rodrigo Luiz Vancini, Claudio Andre Barbosa de Lira, Marilia Santos Andrade

“…However, for females, the CR for softball athletes should be analyzed individually. As there were several differences between the overhead sports according to the FRs, the authors suggest caution in grouping overhead athletes across multiple sports. …”
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How international research consortia can strengthen organisations’ research systems and promote a conducive environment and culture by Justin Pulford, Nadia Tagoe, Yan Ding, Imelda Bates, Susie Crossman, Taghreed El Hajj, Tara Tancred, Lorelei Silvester, Martina Savio, Natasha Bevan

“…Consortia’s actions covered: (a) individuals’ knowledge and skills; (b) capacity strengthening ethos; (c) organisations’ visibility and prestige; and (d) inclusive and responsive management practices. …”
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Transcriptional activity of repair, apoptosis and cell cycle genes (TP53, MDM2, ATM, BAX, BCL-2, CDKN1A, OGG1, XPC, PADI4, MAPK8, NF-KB1, STAT3, GATA3) in chronically exposed perso... by V. S. Nikiforov, E. A. Blinova, A. I. Kotikova, A. V. Akleyev

“…Modulation of the relative content of mRNA of the TP53 (p = 0.013) and BCL-2 (p = 0.021) genes was detected in the group of chronically exposed individuals with the increased intensity of the late stage of apoptosis. …”
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The Use of Patient-Reported Outcomes in Clinical Practice: A National Survey of Hand Surgeons by Stephanie Choo, MD, Rown Parola, MD, Benjamin Kirby, MD, Daniel A. London, MD

“…Results: A total of 419 surveys were completed from the 4,523 individuals contacted, representing a 9.3% response rate. …”
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Correlation between selenium levels and selenoproteins expression in idiopathic generalized epilepsy: a study from Karachi by Hareem Nisar, Rafat Amin, Sadaf Khan, Tehseen Fatima, Qamar-Un-Nisa, Jawwad-Us-Salam

“…Objective This study aimed to determine the serum selenium levels in idiopathic epileptic and healthy individuals. Expression profiling of selenoproteins (GPx1, TRxR1 and SEPW1) both at mRNA and protein levels was also evaluated. …”
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Hepatitis C Virus Screening of High-Risk Patients in a Canadian Emergency Department by Kelsey Ragan, Anjali Pandya, Tristan Holotnak, Katrina Koger, Neil Collins, Mark G. Swain

“…Approximately 0.7% of the Canadian population is infected with hepatitis C virus (HCV), and many individuals are unaware of their infection. Our objectives were to utilize an emergency department (ED) based point-of-care (POC) HCV screening test to describe our local population and estimate the proportion of high-risk patients in our population with undiagnosed HCV. …”
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Environmental risk factors for self-harm during imprisonment: A pilot prospective cohort study. by Thomas Stephenson, Imogen Harris, Charlotte Armstrong, Seena Fazel, Roxanna Short, Nigel Blackwood

“…Multivariable logistic regression models were calculated individually for each predictor.<h4>Results</h4>55.7% of participants completed follow-up (83/149). …”
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Cost-utility of behavioural activation for mitigating psychological impacts of COVID-19 on socially isolated older adults with depression and multiple long-term conditions compared... by Simon Gilbody, Caroline Fairhurst, Catherine Hewitt, Dean McMillan, Carolyn Chew-Graham, Della Bailey, David Ekers, Steve Parrott, Elizabeth Littlewood, Peter Coventry, Han-I Wang, Kalpita Baird

“…Behavioural activation (BA) shows promise as a remote intervention for depression during isolation, but its cost-effectiveness for depressed, socially isolated older adults remains uncertain.Objective This study aimed to assess the cost-utility of BA versus usual care for older adults with depression and MLTCs during COVID-19 restrictions.Methods A randomised controlled trial recruited and randomised individuals aged 65 and over with depressive symptoms and MLTC (n=435) to either the BA intervention or usual care. …”
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Sleep quality among sample of Egyptian patients with Alzheimer’s disease: risk factors and role of genetic profiling for ACE, ACE 2 and APO E genotypes by Khaled Ahmed Elbeh, Mohamed Abdala Abbas, Mohammed H. Hassan, Mohamed Moslem Hefny, Shimaa Fathy Sakr, Reham Bakry Mohamed, Mahmoud Ahmed Bekiet, Tarek Desoky

“…Abstract Background Most individuals having Alzheimer’s disease generally experience increased frequency of awakenings as well as prolonged wakefulness periods at night. …”
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Association between triglyceride/high density lipoprotein ratio and incidence risk of Parkinson’s disease: a population-based cohort study by Yoonkyung Chang, Ju-young Park, Tae-Jin Song

“…During a median of 9.64 years (interquartile range 8.72–10.53), 4,587 individuals (1.47%) had an incidence of PD. Considering the multivariable time-dependent Cox proportional hazard model with repeated measures of average TG/HDL cholesterol ratio, a per unit increase in TG/HDL cholesterol ratio significantly increased the risk of PD in the entire cohort (hazard ratio (HR), 1.010; 95% confidence interval (CI), 1.001–1.020). …”
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Comparative effects of Health Qigong and closed motor exercise on the physical and mental health of female drug rehabilitation participants: a randomized controlled trial by Guang Yang, Deyu Meng, Shichun He, Meiqi Wei, Man Li, Lu Zhang, Zhendong Pan, Ziheng Wang

“…Abstract Background Drug rehabilitation is a challenging process that impacts both the physical and mental health of individuals. Traditional martial arts, such as Health Qigong, and closed motor exercises, such as power cycling, have shown potential benefits in improving health outcomes. …”
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Research through service: Meeting Chinese international college students’ mental health needs by Changming Duan, Jingru Chen, Fenglan Li, Mi Zhou, Xiubin Lin, Shengnan Li

“…These strategies included confiding in trusted individuals, practicing forbearance and self-regulation, and seeking practical solutions to underlying problems. …”
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