Distinct clinical outcomes based on multiple serum cytokine and chemokine profiles rather than autoantibody profiles and ultrasound findings in rheumatoid arthritis: a prospective... by Yukitaka Ueki, Tom W J Huizinga, René E M Toes, Shoichi Fukui, Tomoki Origuchi, Takahiro Maeda, Atsushi Kawakami, Tomohiro Koga, Naoki Matsuoka, Toshihiko Hidaka, Naoki Iwamoto, Mami Tamai, Shin-ya Kawashiri, Akitomo Okada, Ayako Nishino, Tamami Yoshitama, Takahisa Suzuki, Toshimasa Shimizu, Shimpei Morimoto, Tomomi Tsuru, Karin A J van Schie, Masahiro Ayano, Remi Sumiyoshi, Yushiro Endo, Tohru Michitsuji, Kaori Furukawa, Masataka Umeda, Nobutaka Eiraku, Hiroaki Hamada

“…The least absolute shrinkage and selection operator regression of 38 cytokines and chemokines for Clinical Disease Activity Index (CDAI) remission at 12 months resulted in the selection of MIP-1β. …”
Get full text

Risk factors for re-hospitalization within 90 days of discharge for severe influenza in children by Shuo Yang, Sukun Lu, Can Qi, Yinghui Guo, Le Wang

“…Conclusions Our findings suggest that, to reduce the potential readmission of children with severe influenza, a sustained focus on the risk factors including rhinosinusitis and over-activated host immune response during the index hospitalization is needed.…”
Get full text

Theileria annulata infects B-cells in sheep, which display lower dissemination potential compared to T. lestoquardi-infected ovine B-cells by Shahin Tajeri, Perle Latré de Laté, Johanneke D. Hemmink, Christina Vrettou, Gordon Langsley, W. Ivan Morrison

“…The Matrigel traversal index of T. lestoquardi-transformed ovine B-cells was significantly higher than that of T. annulata-transformed ovine B-cells isolated from the same host, consistent with the reported diminished pathogenicity of T. annulata infections in sheep. …”
Get full text

Rockfish abundance, recruitment, and community structure trends in the western Strait of Juan de Fuca, Washington, 2005-2023 by Shawn E. Larson, Katie Shelledy, Daniela Escontrela Dieguez, Jeff Christiansen, Amy Y. Olsen, Zachary Randell, Megan H. Williams, Chris VanDamme, Dayv Lowry, William Jasper

“…Strip transects were conducted annually in August from 2005 through 2023 at five permanently marked index sites. Species-specific relative abundance data for bottomfish were later extracted by biologists from archived video. …”
Get full text

Performance evaluation of HMA using recycled brick powder as filler with Superpave aggregate gradation by Tamiru Habte, Getachew Kebede, Agon Elmer, Anteneh Geremew

“…The RBP specific gravity and plastic index, were 2,66 and non-plastic, respectively. HMA specimens were prepared with conventional filler CSD in three proportions (4, 5, and 6 %) and eight bitumen contents from (3,0-6,5 %) with 5,0 % of CSD selected as the control mix. …”
Get full text

Congenital Heart Disease Fetuses Have Decreased Mid-Gestational Placental Flow, Placental Malperfusion Defects, and Impaired Growth by Rebecca Josowitz, MD, PhD, Deborah Y. Ho, MD, MPH, Somya Shankar, BS, Antara Mondal, MS, Alexis Zavez, PhD, Rebecca L. Linn, MD, Zhiyun Tian, MD, J. William Gaynor, MD, Jack Rychik, MD

“…Results: CHD fetuses had a 15% decrease in mid-gestational UVVF indexed to fetal weight (P < 0.01), and a 27% reduction in UVVF as a proportion of fetal cardiac output (P < 0.01) compared to controls. …”
Get full text

Types, design, implementation, and evaluation of nutrition interventions in older people in Africa: A scoping review protocol. by Anthony Manyara, Tadios Manyanga, Rudo Chingono, Shane Naidoo, Kate Mattick, Grace Pearson, Opeyemi Babatunde, Niri Naidoo, Kate A Ward, Celia L Gregson

“…Searches for Phases 1 and 2 will include bibliographic databases (MEDLINE, EMBASE, Web of Science, African Journals Online, African Index Medicus) and grey literature sources (i.e. relevant websites). …”
Get full text

A Study of Serum Adiponectin Levels in Patients with Polycystic Ovarian Syndrome and its Correlation with Various Cardiometabolic Risk Markers by G. Surendra Prasad, Uma Kaimal Saikia, Ashok Krishna Bhuyan, Abhamoni Baro

“…Settings and Design: In this cross-sectional observational study recently diagnosed, PCOS subjects were compared with age- and body mass index (BMI)-matched controls. Materials and Methods: All the included subjects underwent detailed clinical, biochemical and hormonal evaluation, including lipid profile, 75 g oral glucose tolerance test, fasting serum insulin, fasting serum adiponectin, oxLDL, total testosterone and anti-Mullerian hormone. …”
Get full text

Prevalence and management of hypertension in Turner syndrome: data from the International Turner Syndrome (I-TS) registry by Shani A D Mathara Diddhenipothage, Katharina J Beck, Gayana Amiyangoda, Jillian Bryce, Luminita Cima, Katya De Groote, Yana Deyanova, Evgenia Globa, Gloria Herrmann, Anders Juul, Anna Sophie L Kjaer, Anette Tønnes Pedersen, Sukran Poyrazoglu, Ursina Probst-Scheidegger, Theo C J Sas, Simona Fica, Sumudu Nimali Seneviratne, Justyna Karolina Witczak, Elizabeth Orchard, Jeremy W Tomlinson, S Faisal Ahmed, Helen E Turner

“…In binomial regression analysis, higher body mass index was the only parameter significantly associated with the occurrence of hypertension (B = 1.487, P = 0.004). …”
Get full text

Intervertebral Disc Degeneration in Long-Term Postoperative Patients with Adolescent Idiopathic Scoliosis: MRI Evaluation 34-51 Years after Surgery and its Changes during Middle an... by Tsutomu Akazawa, Toshiaki Kotani, Tsuyoshi Sakuma, Yasushi Iijima, Yoshiaki Torii, Jun Ueno, Atsuhiro Yoshida, Ken Tomochika, Sumihisa Orita, Yawara Eguchi, Kazuhide Inage, Yasuhiro Shiga, Junichi Nakamura, Yusuke Matsuura, Takane Suzuki, Hisateru Niki, Seiji Ohtori, Shohei Minami

“…Scores in the Scoliosis Research Society-22 Questionnaire pain, Roland-Morris Disability Questionnaire, and Oswestry Disability Index were significantly worse in the latest survey than in the previous one. …”
Get full text

Evaluation of 30-day mortality in patients undergoing gastrointestinal endoscopy in a tertiary hospital: a 3-year retrospective survey by Philippe Bichard, Jean-Louis Frossard, Laurent Spahr, Nicolas Goossens, Olivier Chatelanat, Laurent Bochatay, Caroline Bastid

“…Median Charlson Comorbidity Index was 5 (IQR 3–7), and 305/345 procedures (88.4%) were undertaken on patients with an ASA score ≥3. …”
Get full text

Developing clinical prognostic models to predict graft survival after renal transplantation: comparison of statistical and machine learning models by Getahun Mulugeta, Temesgen Zewotir, Awoke Seyoum Tegegne, Mahteme Bekele Muleta, Leja Hamza Juhar

“…The Stochastic Gradient Boosting (SGB) model demonstrated the best discrimination and calibration performance, with a C-index of 0.943 and a Brier score of 0.000351. The Ridge-based Cox model closely followed the SGB model’s prediction performance with better interpretability. …”
Get full text

Composite Primary Outcomes Reported in Studies of Critical Care: A Scoping Review by Prashanti Marella, MD, Sansuka De Silva, Antony G. Attokaran, Kevin B. Laupland, PhD, Lars Eriksson, BA, Mahesh Ramanan, MMed

“…PubMed, Embase, Cumulative Index to Nursing and Allied Health Literature, Scopus, and Cochrane Library from January 2000 to January 2024. …”
Get full text

Loneliness is associated with adverse health behaviour and obesity: a Danish population-based study of 122,258 individuals by Martin Mejlby Jensen, Karina Friis, Helle Terkildsen Maindal, Anne-Sofie Hargaard, Maria Gjaldbaek Knudsen, Marie Stjerne Grønkjaer, Mathias Lasgaard

“…Adverse health behaviours and a higher body mass index (BMI) have been proposed as key mechanisms influencing this association. …”
Get full text

Test-retest reliability of postural control measures in healthy secondary school pupils: insights from the MOVE12 pilot study by Sigbjørn Litleskare, Sigbjørn Litleskare, Svein Barene

“…However, the test-retest reliability of these measurements in field-based conditions is unclear.MethodsThis study aimed to investigate the test-retest reliability of center of pressure measures under field-based conditions, and assess the impact of height, weight, and body mass index (BMI) on test-retest reliability. The study sample comprised 215 upper secondary school pupils (114 girls) aged 16–17 years, all drawn from the control group of a larger intervention study. …”
Get full text

Prolonged nightly fasting in older adults with memory decline: A single-group pilot study exploring changes in cognitive function and cardiometabolic risk factors by Dara L. James, Linda K. Larkey, Molly Maxfield, SeungYong Han, Edward Ofori, Alex E. Mohr, Nanako A. Hawley, Kate Alperin, Erica Ahlich, David E. Vance, Dorothy D. Sears

“…Paired t-tests indicated an increase in cognitive function (Memory and Attention Phone Screener) (p = 0.02) with a medium effect size (Cohen’s d = 0.58) and a decrease in insomnia (Insomnia Severity Index) (p = 0.04) with a medium effect size (Cohen’s d = 0.52). …”
Get full text

Nation-wide cohort of device-measured sedentary time and physical activity in the USA—the Cancer Prevention Study-3 (CPS-3) Accelerometry Substudy: cohort profile by Erika Rees-Punia, Alpa Patel, Jillian Nelson, Peter J Briggs, Nance Joiner, James M Hodge, Jeuneviette E Bontemps-Jones, Den E Bloodworth, Ashley Yeager, Jeshondria McCrary

“…Participants were sedentary for 9.4 hours (564 min, IQR=171 min) and accumulated a median of 6474 steps per day (IQR=5348).Future plans The full CPS-3 cohort will be linked with the National Death Index and state cancer registries biennially. Participants will be sent triennial surveys for the next two decades. …”
Get full text

Sleep deprivation and corneal chronobiology: reevaluating overnight corneal changes by Zsuzsa Zakarné Aszalós, Bence Lajos Kolozsvári, Vivien Lénárt, Dorottya Pásztor, Ziad Hassan, Éva Surányi, Reda Chaker, Mariann Fodor

“…The analysis encompassed keratometric parameters of the cornea’s front (F) and back (B) surfaces, refractive power in flattest and steepest axes (K1, K2), astigmatism (Astig) and its axis (Axis), aspheric coefficient (Asph), corneal pachymetry values of thinnest corneal thickness (Pachy Min) and corneal thickness in the center of the pupil (Pachy Pupil), volume relative to the 3 and 10 mm corneal diagonal (Vol D3, Vol D10) and surface variance index (ISV). Circadian changes were assessed using a hierarchical, mixed-effects linear regression adjusted for age and night shift. …”
Get full text

Left ventromedial prefrontal cortex inhibitory rTMS as an anti-stress intervention in opioid use disorder: Trial design by Tabitha E. Moses, Danielle Lenz, Leslie H. Lundahl, Nicholas A. Mischel, Christine Rabinak, Mark K. Greenwald

“…Stress-induced dysfunction will be indexed with cognitive (e.g., executive function), affective (e.g., emotional arousal), and behavioral (e.g., opioid-seeking) measures pre- and post-rTMS. …”
Get full text

Prevalence of perinatal post-traumatic stress disorder (PTSD) in low-income and middle-income countries: a systematic review and meta-analysis by Charles Opondo, Holly Jenkins, Fiona Alderdice, Gracia Fellmeth, Zoe Daskalopoulou

“…Objectives To systematically synthesise the evidence on prevalence of perinatal post-traumatic stress disorder (PTSD) in low-income and middle-income countries (LMICs).Design Systematic review and meta-analysis.Data sources MEDLINE, Embase, PsycINFO, Scopus, Web of Science, Global Health, Global Index Medicus and the grey literature were searched with no language or date restrictions. …”
Get full text