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    Jiedu Xiaozheng Decoction Augments 5-fluorouracil Induced Anti-hepatic Carcinoma Effect <italic>in Vitro</italic> and <italic>in Vivo</italic> by Zhiyun CAO, Liangpu ZHENG, Wei LIN, Xuzheng CHEN, Xiaoqin ZHU, Jiumao LIN, Wei LIN, Jian DU

    Published 2019-02-01
    “…Significant slowdown in tumor progression compared with control mice was observed in the group of mice receiving 5-FU and EE-JXD, reaching only(0.05±0.01)g tumor volume with in 30 days(<italic>P</italic>&lt;0.01).During 30 days' treatment, the body weight between the control group and the treatment groups were similar(<italic>P</italic>&gt;0.05). Apoptosis index was significantly higher in the 5-FU group compared to the control group(<italic>P</italic>&lt;0.05), and was further increased when EE-JXD combined with 5-FU(<italic>P</italic>&lt;0.01).Conclusion:The present study shows that low-dose 5-FU combined with EE-JXD has a strong anti-cancer effect than 5-FU alone. …”
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