Global, regional, and national burden of esophageal cancer: a systematic analysis of the Global Burden of Disease Study 2021 by Weiqiu Jin, Kaichen Huang, Ziyin Ding, Mengwei Zhang, Chongwu Li, Zheng Yuan, Ke Ma, Xiaodan Ye

“…This study aimed to provide an updated stratified assessment of rates in EC incidence, mortality, and disability-adjusted life-years (DALYs) from 1990 to 2021 by sex, age, and Socio-demographic Index (SDI) at global, regional, and national levels, as well as to project the future trends of EC both globally and regionally. …”
Get full text

Effets du braconnage et des mutilations sur les budgets d’activités et les rapports sociaux des chimpanzés sauvages de Sebitoli dans le parc national de Kibale (Ouganda) by Marie Cibot, Justine Philippon, Romain Laurent, Emmanuelle Pouydebat, Sabrina Krief

“…Deux types de suivi ont été réalisés (février-mai 2013) : (1) un suivi vétérinaire pour décrire les mutilations et l’état sanitaire des chimpanzés blessés, et (2) un suivi comportemental des individus mutilés et valides pour établir des budgets d’activités (observations continues sur 10 min. des individus, n=258) et définir les interactions sociales entre individus via un index d’association entre dyades (observations des compositions et tailles des groupes toutes les 20 min., n=431). …”
Get full text

Episiotomies and obstetric anal sphincter injuries following a restrictive episiotomy policy in France: An analysis of the 2010, 2016, and 2021 National Perinatal Surveys. by Raphaele Houlbracq, Camille Le Ray, Béatrice Blondel, Nathalie Lelong, Anne Alice Chantry, Thomas Desplanches, ENP2021 Study Group

“…For instance, in 2021, 22.3% of women were over 35 years old, 17.7% were born outside of France, 11.3% had a body mass index (BMI) of 30 kg/m2 or higher, and 39.9% were primiparous. …”
Get full text

Comparative analysis of morphologival parameters in isolated and fused L5 spondylolysis patients on the basis of CT features by Rui Ma, Xiaoxia Huang, Luyao Li, Ye Kai, Jun Liu, Gao Leilei, Xiangning Sun, Yong Teng

“…Results There were no significant differences in age, height, weight, body mass index (BMI), or Pfirrmann grade among the three groups. …”
Get full text

治疗前炎症指标构建模型预测卵巢癌患者术后生存 by 李希, 林敏, 马犇, 顾正田, 康佳丽

“…卵巢癌患者四个指标均高于卵巢良性肿瘤患者，差异具有统计学差异（<italic>P </italic>＜0.05）；卵巢癌生存亚组在年龄、FIGO分期、治疗前血清白蛋白水平（37.22±4.86）、NLR （3.12±2.00）、PLR （143.61±54.18）、MLR （0.30±0.17）、NAR ［0.14 （0.11， 0.18）］与死亡亚组的年龄、FIGO分期、治疗前血清白蛋白水平 （34.33±3.73）、NLR （5.38±2.29）、PLR （185.76±64.04）、MLR （0.41±0.19）、NAR ［0.56 （0.19， 0.61）］存在统计学差异（<italic>P</italic> ＜0.05）；多因素分析显示病理分型、腹水、淋巴结转移、NLR、PLR、NAR是卵巢癌患者5年生存的独立预测因素。列线图预测术后生存模型的C-index为 0.865（0.792，0.921），校准预测曲线和理想曲线拟合良好。结论病理分型、腹水、淋巴结转移、治疗前外周血的NLR、PLR、NAR值是卵巢癌患者预后的独立预测因素，以此为基础构建的列线图模型对卵巢癌患者术后生存情况有良好的预测价值。…”
Get full text

Effects of auricular acupoint pressing combined with modified Wendan decoction in the treatment of essential hypertension and accompanying insomnia (耳穴压豆联合加味温胆汤口服治疗原发性高血压伴失眠的效果观察)... by ZHAO Liyun (赵丽云), LIU Qing (刘青), LI Yigen (李乙根), XU Wenwei (徐文伟)

“…The main objective of the study was to evaluate the changes in sleep quality (assessed using the Pittsburgh Sleep Quality Index), anxiety (assessed using the Hamilton Anxiety Scale), depression (assessed using the Hamilton Depression Scale), and blood pressure levels in the two groups before and after treatment. …”
Get full text

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in People Living With HIV Attending Centre of Excellence in HIV Care at a Tertiary Level Teaching Hospital in North... by Ragini Ram, Anuradha Subramanian MD, MSc, FRCP, Rajeshwari K. MD, PhD, FRCPCH

“…A majority (40%) of the subjects were underweight (body mass index [BMI] < 18.5). 22.7% of the male subjects included in the study had MASLD whereas none of the females had fatty changes in the liver on USG. …”
Get full text

Effect of Floating Needle Perfusion Therapy combined with Joint Mobilization on Shoulder Pain of Hemiplegia after Stroke by Xin WANG, Hu LI, Xiuyan LU

“…Before treatment and after treatment for four weeks, the visual analogue scale (VAS) was used to assess shoulder pain, the Fugl-Meyer assessment (FMA) was used to assess upper extremity motor function, the modified Barthel index (MBI) was used to assess activities of daily living, and the goniometer was used to measure the passive range of motion of the shoulder joint.Results:Before treatment, there were no significant differences in VAS scores, FMA scores, MBI scores and PROM of the shoulder joint in three groups, with no statistically significant differences (<italic>P</italic>&gt; 0.05). …”
Get full text

Fitness Profiling in Women Soccer: Performance Characteristics of Elite Turkish Women Soccer Players by Aras Beka Yaşar, Serdar Bayrakdaroğlu, Beyza Yıldız, İbrahim Can

“…Relative and absolute anaerobic power values for elite women football players were obtained as 439,7 (± 61,18 W) and 8,04 (± 1,09 W/kg) for maximal anaerobic power, 316,1 (± 34,46 W) and 5,78 (± 0,56 W/kg) for maximal anaerobic capacity, 193,6 (±22,30 W) and 3,55 (± 0,61 W/kg) for minimal anaerobic power, respectively. In addition, fatigue index values measured as 55,7 (± 3,75 %). Participant’s right and left hand grip strength values were obtained as 30,6 (± 4,62 kg) and 29,6 (± 4,5 kg), back and leg strength values measured as 90,2 (± 18,7 kg) and 101,8 (± 29,5 kg), respectively. …”
Get full text

Decreased vitamin D increase the risk for subclinical hypothyroidism in individuals with T2DM: a cross-sectional study by Yaling Fang, Yaling Fang, Xin Wen, Hui You, Yueye Huang, Shen Qu, Xingchun Wang, Le Bu

“…Thyroid function was compared between groups and their association was analyzed.ResultsBody mass index (BMI), total cholesterol (TCH), triglyceride (TG), and free fatty acid (FFA) were significantly lower in the higher VD group compared to the lower VD group (all p &lt; 0.05). …”
Get full text

Sedentary Behavior and Its Association With Psychological Well-Being and Sleep Quality in Adolescents: Evidence from a Propensity Score Analysis by Zhang L, Zhao S, Zhao S, Zheng H, Ke Y, Yang W, Lei M

“…Psychological health was assessed using the Generalized Anxiety Disorder-7 (GAD-7) scale for anxiety and the Patient Health Questionnaire-9 (PHQ-9) for depression, while sleep quality was measured using the Pittsburgh Sleep Quality Index (PSQI). Self-esteem was evaluated with the Self-Esteem Scale (SES), and social support was measured using the Social Support Rating Scale (SSRS). …”
Get full text

Metabolic Risk Factors and Their Impact on Quality of Life in Patients with Pancreatic Cancer, Acute or Exacerbated Chronic Pancreatitis by I. N. Grigor’eva, O. V. Efimova, N. L. Tov, T. S. Suvorova, D. L. Nepomnyashchikh

“…The presence of arterial hypertension increases the chance of having PC by 2.7 times (p &lt; 0.05). Body mass index parameters, including obesity, as well as parameters of triglycerides, and fasting plasma glucose, did not differ between the groups. …”
Get full text

Efficiency of lung cancer screening in early diagnosis and treatment program among community residents in Nanshan district, Shenzhen city: a cross-sectional and 2-year follow-up su... by Yarui YANG, Xujun GUO, Yuzheng FAN, Han WANG, Shengbin LI, Juan HE, Chang MA, Junbo BAI, Shengyuan LIU

“…For the screening program, the total cost was 1.304 million Chinese yuan (CNY); the per capita cost was 157.8 CNY; the cost-effectiveness ratio (CER) for each confirmed lung cancer case was 82 000 CNY; the average cost for each early-diagnosed lung cancer case was 93 000 CNY; and the early detection cost index (EDCI) was 0.22. The above indicators suggest a high cost-effectiveness of the program. …”
Get full text

Mechanism of Acupuncture Therapy on RANKL/OPG Signaling Pathway to Regulate Bone Metabolism Balance in Osteoporosis Model Rats by Qin YIN, Hong PAN, Xiaojuan DING, Xiaoguang QIN, Xiaorong GUO

“…Sp), structural model index(SMI)were analyzed by Micro-CT;TUNEL method was used to detect apoptosis of distal femur cells in four groups;Western blot and RT-PCR method were used to detect the protein expression levels of RANKL, OPG mRNA in femur and hypothalamus in four groups.Results:①BMD and bone metabolism markers: compared with the blank group, BMD, BALP, CBF-α1, CTX-I, PINP and OC in the model group were significantly decreased(<italic>P</italic>&lt;0.05). …”
Get full text

Association of Estimated Glomerular Filtration Rate (eGFR) and High-Sensitivity C-Reactive Protein (Hs-CRP) with the Risk of New-Onset Atrial Fibrillation in Patients with Diabetes by Liu Y, Liu H, Sun D, Zheng Y, Tse G, Chen K, Qiu J, Wu S, Liu T

“…We employed multivariable Cox regression analysis to evaluate the relationships between eGFR, hs-CRP, and new-onset AF, adjusting for confounders including smoking status, alcohol consumption, blood pressure, fasting blood glucose (FBG), heart rate, lipid levels, body mass index (BMI), and medication usage. Competing risk analysis was also performed.Results: Among 16,516 patients, 222 developed new-onset AF over a mean follow-up of 12.6 years. …”
Get full text

Application of home-based exercise therapy in community-dwelling elderly patients with mild cognitive impairment and depression (以家庭为基础的运动疗法在社区老年轻度认知障碍伴抑郁患者中的应用研究)... by ZHU Haiying (诸海英), PEI Hua (裴华), YUAN Hongyan (袁红艳), ZHANG Lianhua (张莲花)

“…The Geriatric Depression Scale(GDS), The Montreal Cognitive Assessment (MoCA), Brathel Index (BI) for Activity of Daily Living were adopted for effectiveness assessment of exercise therapy on cognitive function, depression level and daily living ability of patients. …”
Get full text

An exploratory study of INPP4B, a biomarker of gemcitabine chemoresistance in pancreatic cancer by REN Jiaqiang, WU Shuai, SU Tong, LI Jie, HAN Liang, WU Zheng

“…Results: The half maximal inhibitory concentration (IC50) for gemcitabine was significantly higher in the gemcitabine-resistant cell strain (Mia GR) than in the wild-type cell line (Mia WT) (258.10 μmol/L vs 0.18 μmol/L), with a resistance index (RI) of 1 443.9. Transcriptome sequencing identified 3 985 differentially expressed genes, of which 25 were shared with the GEO datasets. …”
Get full text

Effect of Aerobic Treadmill Exercise Regulating Glucose Transporter 9 on Renal Function in Hyperuricemia Rats by LIANG Jiarong, YANG Huan, CUN Yongdan, WANG Lihuan, LI Yijie, YE Bin

“…Hematoxylin-eosin (HE) was used to stain the renal histopathological section, and the microscope (×400) was used to observe the structural changes of renal tubules and glomerulus; the peroxidase method was used to detect the renal function indexes such as uric acid (UA), creatinine (Cre) and urea nitrogen (BUN); enzyme-linked immunosorbent assay (ELISA) method was used to determine the contents of interleukin-1β (IL-1β) in serum and kidney tissues; Western blot was used to detect the expressions of Caspase-1, IL-1β and glucose transporter 9 (GLUT-9) in the kidney tissues.Results① Pathological examination results: there was not obvious pathological changes were observed in the kidney tissues of the Control group; in the Model group, the renal tissue capsule was incomplete, the glomerulus was deformed and atrophic, and the renal tubules were disordered; in the Exercise group, the number of inflammatory cell infiltration was significantly decreased, the renal tubular structure was relatively intact, and the pathological changes such as cytoplasmic vacuolation of renal tubular epithelial cells were significantly decreased. ② UA, Cre and BUN content of serum: compared with the Control group, UA, BUN and Cre content in serum of the Model group and Exercise group was significantly increased (<italic>P</italic>&lt;0.05); compared with the Model group, UA, BUN and Cre content in serum of the Exercise group were significantly decreased (<italic>P</italic>&lt;0.05). ③ Serum and kidney IL-1β content: compared with the Control group, the expression of IL-1β in serum and kidney of the Model group and the Exercise group were significantly increased (<italic>P</italic>&lt;0.05); compared with the Model group, the expression of IL-1β in serum and kidney of the Exercise group was significantly decreased (<italic>P</italic>&lt;0.05). ④ Expressions of Caspase-1, IL-1β and GLUT-9 protein: compared with the Control group, the expressions of Caspase-1, IL-1β and GLUT-9 protein in kidney tissues of the Model group and the Exercise group were significantly increased (<italic>P</italic>&lt;0.05); compared with the Model group, the expressions of Caspase-1, IL-1β, and GLUT-9 protein in kidney tissues of the Exercise group were significantly decreased (<italic>P</italic>&lt;0.05).ConclusionAerobic treadmill exercise can effectively reduce the level of uric acid and inflammatory response of hyperuricemia rats, and improve renal function, which may be related to the regulation of GLUT-9 protein expression.…”
Get full text

Effect of Lingnan Painless Apitherapy combined with McKenzie Therapy on Patients with Lumbar Disc Herniation by Hongbo WU, Xinghua CHEN, Ruike ZHANG, Qinglu LUO, Yongming CHENG

“…Objective:To observe the clinical efficacy of Lingnan painless apitherapy combined with McKenzie therapy on patients with lumbar disc herniation(LDH).Methods:A total of 80 patients with LDH who were treated in the department of rehabilitation medicine of the fifth affiliated hospital of Guangzhou medical university from February 2019 to June 2020 were randomly divided into the control group and the observation group according to the random number table method, with 40 cases in each group.The control group received magnetic thermal-vibration therapy and McKenzie therapy.The Japanese magnetic thermal-vibration therapy instrument(TM-3200)was used in the magnetic thermotherapy, the appropriate intensity(high, hot, warm and low temperature)was selected according to the patient's feeling and symptoms, 20 minutes each time, once a day, seven times a week, continuous treatment for two weeks.In addition, the patients with LDH received McKenzie therapy, which was assisted by the therapist or the patient actively completed the flowing training, such as prone position stretching, prone position stretching combined with compression, standing position lateral movement and so on.Each step rested for one minute, once every two days, continuous treatment for two weeks.The observation group received Lingnan painless apitherapy on the basis of treatment in the control group after half an hour's rest.Before treatment, the patients were given apitherapy tolerance test, performing apitherapy with one bee on each Zusanli acupoints on both sides.After apitherapy for 15 minutes, if there was no adverse reaction, the patients were given painless apitherapy with a quiet and comfortable environment, every other day.In this treatment, both sides of Huatuo Jiaji acupoints on the lumbar spinous processes were selected, and Huatuo Jiaji acupoints on both sides of the 5th lumbar spinous process were selected in the first treatment, one acupoint on the left and one on the right.After that, two acupoints were added each time, and each acupoint was treated by one bee.According to the order of Jiaji points on the 4th, 3rd, 2nd and 1st lumbar vertebrae, the number of bee needles increased to 10 bees.Before treatment and two weeks after treatment, visual analogue scales(VAS)was used to evaluate the pain degree, Oswestry disability index(ODI)was used to assess the lumbar spine dysfunction, and TCM syndrome score was used to evaluate the therapeutic effect, and the clinical efficacy was evaluated by <italic>the diagnosis and curative effect standards of TCM diseases</italic>.Results:Before treatment, there was no significant difference in the VAS score, ODI score and TCM syndrome score between the observation group and the control group(<italic>P</italic>&gt;0.05).Compared with treatment before, the VAS score, ODI score and TCM syndrome score after treatment for two weeks of the two groups were significantly reduced, with a statistically significant difference(<italic>P</italic>&lt;0.05).Compared with the control group, the VAS score and TCM syndrome score of the observation group were lower than those of the control group, with a statistically significant difference(<italic>P</italic>&lt;0.05), but there was no considerable difference in ODI score between the two groups(<italic>P</italic>&gt;0.05), and the clinical efficacy of the observation group(95%)was significantly higher than that of the control group(80%)(<italic>P</italic>&lt;0.05).Conclusion:Lingnan painless apitherapy combined with McKenzie therapy can significantly improve the pain degree and lumbar spine dysfunction of patients with LDH, which have a good effect and it is worthy of clinical promotion.However, it's necessary to develop large-sample randomized controlled trials and follow-up, to provide more reliable basis for clinical treatment of LDH.…”
Get full text

Global, regional, and national burdens of heart failure in adolescents and young adults aged 10–24 years from 1990 to 2021: an analysis of data from the Global Burden of Disease St... by Chengzhi Yang, Yuhe Jia, Changlin Zhang, Zening Jin, Yue Ma, Xuanye Bi, Aiju Tian

“…In addition, the HF trends by age, sex, and socio-demographic index (SDI) were analyzed. Furthermore, we calculated the average annual percentage changes (AAPC) and identified the year with the most pronounced changes in the trends with the joinpoint regression analysis. …”
Get full text