Modulating the coordination environment of cobalt porphyrins for enhanced electrochemical nitrite reduction to ammonia by Jingwei Han, Hai Sun, Fengkun Tian, Wenwen Zhang, Zonghang Zhang, Ping She, Jun‐Sheng Qin, Heng Rao

“…Under neutral, non‐buffered conditions over a wide potential range (−1.0 to −1.5 V versus AgCl/Ag), the Faradaic efficiency of nearly 90% for ammonia was achieved and reached 94.5% at −1.4 V versus AgCl/Ag, with an ammonia yield of 6,498 μg h−1 and a turnover number of 22,869 at −1.5 V versus AgCl/Ag. In situ characterization and density functional theory calculations reveal that modulating the coordination environment alters the electron transfer mode of the cobalt active center and the charge redistribution caused by the break of the ligand field. …”
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Wnt/ β-catenin and CTNNB1 gene mutation in hepatocellular carcinoma, a case study in Egyptian patients by Ramy A. Abdelsalam, Ibrahim M. El-Shawaf, Azza Abdel-Aziz, Tarek A. Bismar, Shaimaa M. Yussif

“…Detection and scoring of CTNNB1 gene mutation were done by Chromogenic In Situ Hybridization (CISH). The relation between aberrant β-Catenin, Wnt2 IHC staining and CTNNB1 mRNA expression and different clinicopathological characteristics was studied. …”
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Imaging Flow Cytometric Identification of Chromosomal Defects in Paediatric Acute Lymphoblastic Leukaemia by Ana P. A. Simpson, Carly E. George, Henry Y. L. Hui, Ravi Doddi, Rishi S. Kotecha, Kathy A. Fuller, Wendy N. Erber

“…We aimed to assess the applicability of a new imaging flow cytometry methodology that incorporates cell morphology, immunophenotype, and fluorescence in situ hybridisation (FISH) to identify aneuploidy of chromosomes 4 and 21 and the translocation <i>ETV6::RUNX1</i>. …”
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The Small Mobile Ozone Lidar (SMOL): instrument description and first results by F. Chouza, T. Leblanc, P. Wang, S. S. Brown, K. Zuraski, K. Zuraski, W. Chace, W. Chace, W. Chace, C. C. Womack, C. C. Womack, J. Peischl, J. Peischl, J. Hair, T. Shingler, J. Sullivan

“…The comparison with airborne in situ and lidar measurements shows very good agreement, with systematic differences below 10 % throughout most of the measurement range. …”
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Geological characteristics and main enrichment controlling factors of coalbed methane in Nanchuan area, southeastern Sichuan Basin by Xipeng HE, Kaiming WANG, Wei LUO, Yuqiao GAO, Nana LIU, Tao GUO, Yatong ZHOU, Didi WU

“…It is characterized by "high gas content, abundant free gas, and oversaturation", and its gas content increases with burial depth. (4) The in-situ stress in the study area is moderate (35 to 60 MPa), with a small two-way horizontal stress difference coefficient (< 0.1) and good roof and floor plates, forming effective stress shielding favorable for fracturing transformation. (5) The main controlling factors for CBM methane enrichment in the Nanchuan area include the sedimentary environment, which determines coal-bearing formations; the degree of coal evolution, which determines the intensity of hydrocarbon generation; and the preservation conditions, which govern CBM enrichment.…”
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Angiotensin IV Receptors in the Rat Prefrontal Cortex: Neuronal Expression and NMDA Inhibition by Zsolt Tamás Papp, Polett Ribiczey, Erzsébet Kató, Zsuzsanna E. Tóth, Zoltán V. Varga, Zoltán Giricz, Adrienn Hanuska, Mahmoud Al-Khrasani, Ákos Zsembery, Tibor Zelles, Laszlo G. Harsing, László Köles

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Review and syntheses: Ocean alkalinity enhancement and carbon dioxide removal through marine enhanced rock weathering using olivine by L. J. J. Geerts, A. Hylén, F. J. R. Meysman, F. J. R. Meysman

“…From our analysis, we conclude that the current knowledge base is not sufficient to predict the outcome of in situ mERW applications. Particularly, the impact of pore-water saturation on the olivine dissolution rate and the question of the additionality of alkalinity generation remain critical unknowns. …”
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Barcoded screening identifies nanocarriers for protein delivery to kidney by Luyao Wang, Wen Zhou, Hang Chen, Xiangqian Jia, Peiyuan Zheng, Haolin Jiang, Mengling Wu, Yaning Zhang, Yanchao Ding, Yexi Peng, Rui Zhu, Tiantian Li, Boxue Tian, Bujie Du, Juanjuan Du

“…We construct a nanocapsule library via in-situ polymerization, incorporating various monomers to create nanocapsules with unique surface properties. …”
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Efficient continuous SF6/N2 separation using low-cost and robust metal-organic frameworks composites by Jinjian Li, Yuting Chen, Tian Ke, Yuanyuan Jin, Rongrong Fan, Guihong Xu, Liu Yang, Zhiguo Zhang, Zongbi Bao, Qilong Ren, Qiwei Yang

“…Record-high selectivities (> 2×104) and SF6 dynamic capacities (~ 2.7 mmol/g) were achieved, while exceptional SF6 productivities (~ 58.7 L/kg), yields (~ 96.8%), and recyclability (~ 1000 cycles) were demonstrated in fixed-bed adsorption-desorption experiments under mild regeneration conditions. 2D solid-state NMR/in-situ FTIR, DFT-D binding/diffusion simulation analyses revealed the multi-site binding mode and the ultra-fast diffusion of SF6 within the channels. …”
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Safeguarding and using global banana diversity: a holistic approach by Ines Van den houwe, Rachel Chase, Julie Sardos, Max Ruas, Els Kempenaers, Valentin Guignon, Sebastien Massart, Sebastien Carpentier, Bart Panis, Mathieu Rouard, Nicolas Roux

“…In more than 35 years of activity, the ITC has distributed over 18,000 banana accession samples to researchers and farmers in 113 countries. Ex situ conservation of vegetatively-propagated crops such as banana poses very particular challenges. …”
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Isolated FeN3 sites anchored hierarchical porous carbon nanoboxes for hydrazine‐assisted rechargeable Zn‐CO2 batteries with ultralow charge voltage by Sanshuang Gao, Hongyi Li, Zhansheng Lu, Songjie Meng, Xue Zhao, Xinzhong Wang, Xijun Liu, Guangzhi Hu

“…Benefitting from the bifunctional ECO2R and HzOR catalytic activities, the homemade hydrazine‐assisted rechargeable ZCBs assembled with the Fe‐HPCN air cathode exhibited an ultralow charge voltage (decreasing by ~1.84 V), excellent CO selectivity (FECO close to 100%), and high 89% energy efficiency. In situ infrared spectroscopy confirmed that Fe‐HPCN can generate rate‐determining *N2 and *CO intermediates during HzOR and ECO2R. …”
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Science highlights from the Kjell Henriksen Observatory on Svalbard by Katie Herlingshaw, Noora Partamies, Charlotte M. van Hazendonk, Mikko Syrjäsuo, Lisa J. Baddeley, Magnar G. Johnsen, Nina K. Eriksen, Ian McWhirter, Anasuya Aruliah, Mark J. Engebretson, Kjellmar Oksavik, Fred Sigernes, Dag A. Lorentzen, Takanori Nishiyama, Matthew B. Cooper, John Meriwether, Stein Haaland, Daniel Whiter

“…KHO’s diverse instrumentation, combined with other co-located optical and radar infrastructure, and in situ measurements from satellites and sounding rockets, has paved the way for impactful multi-instrument studies. …”
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Breast Cancer Survivors’ Diet and Physical Activity Preferences and Barriers: How COVID-19 Changed the Intervention Landscape by Xin Chen, Chungyi Chiu, Helen Hoi Ting Cheung, Sylvia L Crowder, Xi Chen, Linda Trinh, Anna E Arthur

“…Methods: A cross-sectional survey was administered to adults diagnosed with ductal carcinoma in situ or stage I–IV breast cancer (BC) from 2019 to 2021 regarding interest, preferences, and barriers to participating in diet and exercise interventions. …”
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Evaluation of X-Inactivation Status and Cytogenetic Stability of Human Dermal Fibroblasts after Long-Term Culture by Zhi-Gang Xue, Zhan-Ping Shi, Juan Dong, Ting-Ting Liao, Yan-Peng Wang, Xue-Ping Sun, Zheng-Jie Yan, Xiao-Qiao Qian, Yu-Gui Cui, Juan Chen, Jia-Yin Liu, Guoping Fan

“…Consistently, DNA fluorescent in situ hybridization (FISH) identified 3-4 copies of X chromosomes in one nucleus in this subset of cells with two inactive Xs. …”
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An Enhanced Three-Band Algorithm for Retrieving Phycocyanin Concentration from Satellite Data in Plateau Inland Lake by Dajun Yuan, Bo-Hui Tang, Dong Wang, Junyi Chen, Zhen Zhang, Zhitao Fu

“…Since the PC absorption feature at 620 nm is prone to interference from non-PC pigments, the algorithm incorporates the quantification of the absorption coefficient of non-PC pigments at 620 nm (<inline-formula><tex-math notation="LaTeX">${{{\bm{a}}}_{{\bm{ph}} - {\bm{pc}}}}( {620} )$</tex-math></inline-formula>) to improve the accurate of estimating <inline-formula><tex-math notation="LaTeX">${{{\bm{a}}}_{{\bm{pc}}}}( {620} )$</tex-math></inline-formula>. Using in situ observation data from Erhai Lake as an example, the results show that ETBA significantly outperforms the original three-band algorithm in mitigating interference from non-PC pigments. …”
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New insights into interspecies relationships, chromosomal evolution, and hybrid identification in the Lycoris Herb. by Yue Zhang, Shujun Zhou, Yu Chen, Pengchong Zhang, Yongchun Zhang, Junhuo Cai, Zixuan Nie, Lu Zhang

“…This study utilizes karyotype structure, genome size, and fluorescent in situ hybridization (FISH) technology to explore the chromosomal evolution and hybrid identification of Lycoris employing three approaches at the cytogenetic level. …”
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Study on the protective effect of naringin-regulated lncRNA GAS5 against mitochondrial apoptosis in osteoarthritic chondrocytes by LIN Qin, ZHU Yingkai, LIN Yanming, LAN Shujie, CHEN Changxing, FU Changlong

“…In vitro experiments, Lenti-lncRNA GAS5 was used to infect sodium nitroprusside (SNP)-induced chondrocytes, and the expression of lncRNA GAS5 was detected by fluorescence in situ hybridization in rat chondrocytes; after silencing of lncRNA GAS5, the expression level of lncRNA GAS5 in rat chondrocytes was detected by Real-time PCR; Western blot detected the protein levels of Caspase-3, Bax, MMP-13 and Cyt-C.Results① Pathological changes of cartilage tissue: The articular cartilage matrix in naringenin group was relatively complete, the surface was relatively smooth, the structure was clear, the tide line was more complete, the number of chondrocytes was more full, the arrangement was more orderly, the cartilage staining was more uniform, and the structure was significantly restored than that in the model group. ② lncRNA GAS5 expression in cartilage tissue: Compared with model group, lncRNA GAS5 expression in naringin group was decreased (<italic>P</italic>&lt;0.01). ③ Expression of proteins related to mitochondrial apoptosis in cartilage tissues: Compared with model group, the expressions of Caspase-3, Bax, MMP-13 and Cyt-C in cartilage tissues of naringin group were decreased (<italic>P</italic>&lt;0.01). ④ Fluorescence expression of lncRNA GAS5 in chondrocytes: FISH results showed that the fluorescence expression of lncRNA GAS5 was decreased after naringin treatment of SNP-induced chondrocytes (<italic>P</italic>&lt;0.01). ⑤ The protein expressions of Caspase-3, Bax, MMP-13 and Cyt-C in chondrocytes: Compared with the model group, the protein expressions of Caspase-3, Bax, MMP-13 and Cyt-C in naringin group were significantly decreased (<italic>P</italic>&lt; 0.01). …”
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The Clinicopathological Features and Prognostic Significance of HER2-Low in Early Breast Tumors Patients Prognostic Comparison of HER-Low and HER2-Negative Breast Cancer Stratified... by Sanaa Gamrani, Laila Akhouayri, Sara Boukansa, Mehdi Karkouri, Hinde El Fatemi

“…A new nomenclature has been proposed for HER2 1+ and HER2 2+ tumors that are confirmed negative according to fluorescence in situ hybridization (FISH). These tumors are now referred to as HER2-low, and it is thought that they may represent a distinct subtype of breast cancer that warrants further investigation. …”
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Detecting glacial lake water quality indicators from RGB surveillance images via deep learning by Zijian Lu, Xueyan Zhu, Jinfeng Li, Mingyue Li, Jie Wang, Wenqiang Wang, Yili Zheng, Qianggong Zhang

“…In this study, we synchronized surveillance monitoring with in-situ water quality measurements at a typical high-altitude glacial lake on the Qinghai-Tibet Plateau. …”
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Formation and fate of freshwater on an ice floe in the Central Arctic by M. M. Smith, N. Fuchs, E. Salganik, D. K. Perovich, I. Raphael, M. A. Granskog, K. Schulz, M. D. Shupe, M. D. Shupe, M. Webster

“…Additionally, the contribution from stored precipitation (snowmelt) outweighs by 5 times the input from in situ summer precipitation (rain). The magnitude and rate of local meltwater production are remarkably similar to those observed on the prior Surface Heat Budget of the Arctic Ocean (SHEBA) campaign, where the cumulative summer freshwater production totaled around 1 m during both. …”
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