A Simple Methodology for Conversion of Mouse Monoclonal Antibody to Human-Mouse Chimeric Form by Vinh T. Dang, Kedar D. Mandakhalikar, Oi-Wing Ng, Yee-Joo Tan

“…Passive immunotherapy has mainly been used as a therapy against cancer and inflammatory conditions. …”
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Development of animal models to study aggressive thyroid cancers by Shovan Dutta, Jeffrey A Knauf

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NGcGM3 Ganglioside: A Privileged Target for Cancer Vaccines by Luis E. Fernandez, Mariano R. Gabri, Marcelo D. Guthmann, Roberto E. Gomez, Silvia Gold, Leonardo Fainboim, Daniel E. Gomez, Daniel F. Alonso

“…Active specific immunotherapy is a promising field in cancer research. …”
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Natural products as part of triple negative breast cancer by Yozlem Kobakova, Maria Moneva-Sakelarieva, Spiro Konstantinov, Georgi Momekov, Stefka Achkova Ivanova, Ventseslava Atanasova, Maria Chaneva, Radoslav Tododrov, Nikolay Bashev, Petar Atanasov

“…Various treatment options are available, such as chemotherapy, immunotherapy, radiation therapy, and surgery. Chemotherapy is the most common of these options. …”
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Dysregulation of NK and CD8+T Cells by the Microbiota Promotes the Progression of Lung Cancer by Shouxin Hu, Yanfang Zha, Wenwen Yang, Kele Cui, Min Cheng

“…Our findings reveal the role of the microbiota in reshaping tumour-related immune responses involving NK cells and CD8+T cells and shed light on the clinical immunotherapy of lung cancer.…”
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NOS2 as a prognostic biomarker for early-onset colorectal cancer based on public data and clinical validation analysis by Chaoqun Xing, Lipeng Zhao, Weiwei Zou, Xie Peng, Xiao-Liang Xing, Jie Li

“…The results suggested that NOS2 can be used as a potential biomarker for EOCRC, which can be used for prognosis and guidance of immunotherapy and chemotherapy.…”
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Radiotherapy for Melanoma: More than DNA Damage by Susanne J. Rogers, Emsad Puric, Brigitte Eberle, Niloy R. Datta, Stephan B. Bodis

“…Melanoma is a highly immunogenic tumour and in this era of immunotherapy, there is renewed interest in the potential of irradiation, not only as an adjuvant and palliative treatment, but also as an immune stimulant. …”
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Exploring the genetic profiles linked to senescence in thyroid tumors: insights on predicting disease progression and immune responses by Baoliang Zhang, Yanping Pang

“…The proposed model not only accurately predicts patient survival but also reveals factors related to immunotherapy response, offering new perspectives for personalized medicine.…”
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Exploring practical experience with different treatments in NSCLC patients with MET-deregulated: a retrospective analysis from the real world by Mengmeng Li, Jiuyan Huang, Ruyue Xing, Xinyang Du, Chunhua Wei, Huijuan Wang

“…Results Among METex14 skipping mutations patients (n = 57), median progression free survival (PFS) was: Chemotherapy 7.64 m, Crizotinib 8.5 m, Savolitinib 9.3 m, and Immunotherapy 3.87 m. Targeted therapies and chemotherapy significantly outperformed Immunotherapy. …”
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Pan-cancer characterization of m6A-mediated regulation of T cell exhaustion dynamics and clinical relevancies in human cancers by Weiping Ji, Ye Fang, Liwei Chen, Yitong Zheng, Yifei Pei, Changqiu Mei, Meng Zhou

“…T cell exhaustion (TEX) is a major barrier to effective immunotherapy. The role of N6-methyladenosine (m6A) modification in regulating immune cell function has been recognized, but its impact on TEX dynamics across cancer types and clinical outcomes remains unclear. …”
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D-mannose promotes diabetic wound healing through inhibiting advanced glycation end products formation in keratinocytes by Jialiang Luo, Tianxing Wu, Jing Zhang, Zhicheng Liang, Weijie Shao, Di Wang, Lei Li, Daming Zuo, Jia Zhou

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Comparison of Efficacy and Safety of First-Line Treatment Options for Unresectable Stage III Non-Small Cell Lung Cancer: A Retrospective Analysis by Luqing Zhao, Zhiting Zhao, Xiaoqi Yan, Fei Wu, Ning Sun, Renhong Guo, Shaorong Yu, Xiao Hu, Jifeng Feng

“…For unresectable stage III NSCLC patients with wild-type driver genes, the combination of radiotherapy and immunotherapy in the initial treatment was essential to significantly improve the efficacy. …”
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CoviWall, a whole-virion-inactivated B.1.617.2 vaccine candidate, induces potent humoral and Th1 cell response in mice and protects against B.1.617.2 strain challenge in Syrian ham... by Jyotsna Dandotiya, Neeta Adhikari, Manas Ranjan Tripathy, Manas Ranjan Tripathy, Kamini Jakhar, Sudipta Sonar, Dibya Ranjan Pati, Vibhu Kanchan, Varsha S. Prasad, Jitendra Kumar, Nitesh K. Senapati, Arti Bharmoria, Neeraj Rani, Monika Lakhanpal, CS. Patil, Nishan Singh, Lovely Khan, Lavit Jambu, Naveen K. Jain, Syed Khalid Ali, Priyanka Priyadarsiny, Amulya K. Panda, Rajesh Jain, Shailendra Mani, Sweety Samal, Amit Awasthi, Amit Awasthi, Zaigham Abbas Rizvi, Zaigham Abbas Rizvi

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REVIEW by Claudia-Ştefania Bala

“…Iron, ferroptosis and association with tumoral evolution and potential therapeutic impact Decision making in Merkel cell carcinoma – surgical oncologist point of view Cardiac toxicity of checkpoint inhibitors (CPI) used in cancer immunotherapy Immune-mediated complications of monoclonal antibodies used in onco-hematology …”
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Immunotherapeutic Approaches in Triple-Negative Breast Cancer: State of the Art and Future Perspectives by Karima Oualla, Loay Kassem, Lamiae Nouiakh, Lamiae Amaadour, Zineb Benbrahim, Samia Arifi, Nawfel Mellas

“…In this article, we tried to explain the rationale and mechanisms of targeting the immune system in TNBC, to report the results from recent clinical trials that put immunotherapy as a new standard of care in TNBC in addition to ongoing trials and future directions in the next decade.…”
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Potentiating intratumoral therapy with immune checkpoint inhibitors: shifting the paradigm of multimodality therapeutics by B.E. Nelson, A. Naing, S. Fu, R.A. Sheth, R. Murthy, S. Piha-Paul

“…The tumor microenvironment plays a critical role in immunotherapy resistance, characterized by immune cell composition, regulatory factors, and tumor mutational burden. …”
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Influence of different formulations and process parameters during the preparation of drug-loaded PLGA microspheres evaluated by multivariate data analysis by Vysloužil Jakub, Doležel Petr, Kejdušová Martina, Mašková Eliška, Mašek Josef, Lukáč Robert, Košťál Vratislav, Vetchý David, Dvořáčková Kateřina

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A Cell Differentiation Trajectory-Related Signature for Predicting the Prognosis of Lung Adenocarcinoma by Fan Yang, Yan Zhao, Xiaohan Huang, Jin Zhang, Ting Zhang

“…Then, the consensus clustering analysis was carried out on TCGA-LUAD samples, and the GSEA analysis was performed, then the differences on the expression levels of immune checkpoint genes and immunotherapy response were compared among clusters. …”
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MHC Class 1 and PDL-1 Status of Primary Tumor and Lymph Node Metastatic Tumor Tissue in Gastric Cancers by Ibrahim Halil Erdogdu

“…Despite the use of VEGF-, EGFR-, and HER2-targeting agents, prognosis is still poor in advanced gastric cancer. Although cancer immunotherapy responds well in some patients, clinical use is limited due to unanswered patients. …”
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CpG Oligodeoxynucleotides Enhance the Efficacy of Adoptive Cell Transfer Using Tumor Infiltrating Lymphocytes by Modifying the Th1 Polarization and Local Infiltration of Th17 Cells by Lin Xu, Chunhong Wang, Zhenke Wen, Ya Zhou, Zhongmin Liu, Yongjie Liang, Zengguang Xu, Tao Ren

“…Adoptive cell transfer immunotherapy using tumor infiltrating lymphocytes (TILs) was an important therapeutic strategy against tumors. …”
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