Showing 1,041 - 1,060 results of 1,132 for search '"immunosuppression"', query time: 0.09s Refine Results
  1. 1041

    African animal trypanocide resistance: A systematic review and meta-analysis by Keneth, Iceland Kasozi, Ewan, Thomas MacLeod, Susan, Christina Welburn

    Published 2024
    “…Major markers of resistance explored include TbAT1, P1/P2 transporters, folate transporters, such as F-I, F-II, F-III, and polyamine biosynthesis inhibitors. In addition, immunosuppressed hosts favor the development of AATr.…”
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    Article
  2. 1042

    Enhanced Suppressive Activity of Regulatory T Cells in the Microenvironment of Malignant Pleural Effusions by Joanna Budna, Mariusz Kaczmarek, Agata Kolecka-Bednarczyk, Łukasz Spychalski, Piotr Zawierucha, Joanna Goździk-Spychalska, Michał Nowicki, Halina Batura-Gabryel, Jan Sikora

    Published 2018-01-01
    “…Understanding of relations between cellular and cytokine immunosuppressive factors in tumor microenvironment may determine success of anticancer response.…”
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    Article
  3. 1043

    Exploring the Mechanism of Skeletal Muscle in a Tacrolimus-Induced Posttransplantation Diabetes Mellitus Model on Gene Expression Profiles by Chenlei Zheng, Cheng Wang, Tan Zhang, Ding Li, Xiao-feng Ni, Jian-Hu Lin, Linxiao Sun, Bicheng Chen

    Published 2020-01-01
    “…Tacrolimus (Tac or FK506) is a widely used immunosuppressant that has been reported to be a risk factor for PTDM and to further induce complications in heart and skeletal muscles, but the mechanism is still largely unknown. …”
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    Article
  4. 1044

    Lipid nanoparticles deliver DNA-encoded biologics and induce potent protective immunity by Dafei Chai, Junhao Wang, Jing Ming Lim, Xiaohui Xie, Xinfang Yu, Dan Zhao, Perry Ayn Mayson Maza, Yifei Wang, Dana Cyril-Remirez, Ken H. Young, Yong Li

    Published 2025-01-01
    “…Single-cell RNA sequencing (scRNA-seq) analysis revealed that the LNP-M/pSpike vaccine enhanced CD80 activation signaling in CD8+ T cells, NK cells, macrophages, and DCs, while reducing the immunosuppressive signals. The enrichment of TCR and BCR by LNP-M/pSpike suggested an increase in immune response specificity and diversity. …”
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    Article
  5. 1045

    Development of Fulminant Type 1 Diabetes Mellitus in a Patient with DRESS Syndrome by Pedro Perez, Wilson Sze, Daniel Lozeau, Dipa Avichal, Joshua Miller

    Published 2020-01-01
    “…She had numerous complications including significant facial edema, seizures, bacterial pneumonia, sepsis, hypovolemic shock, acute respiratory distress syndrome, diabetic ketoacidosis, nonalcoholic steatohepatitis, liver failure, and recurring DRESS rashes despite treatment with high-dose intravenous steroids and immunosuppressants. During this time, the patient developed a rare form of uncontrolled type 1 diabetes mellitus not explained by autoantibody production or continued high-dose steroid use. …”
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    Article
  6. 1046

    Development of chimeric Nanobody-Granzyme B functionalized ferritin nanoparticles for precise tumor therapy by Baijin Xia, Huolun Feng, Xinmiao Jiang, Jialing Guo, Keming Lin, Wenxing Zhang, Fan Xing, Lixue Cao, Yong Li, Hui Zhang, Xu Zhang, Wenyu Li, Fei Yu

    Published 2025-03-01
    “…The efficacy of traditional T-cell therapies, including chimeric antigen receptor (CAR) T cells, is often constrained by immunosuppressive factors and the tumor microenvironment. …”
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    Article
  7. 1047

    The Different Effects of IFN-β and IFN-γ on the Tumor-Suppressive Activity of Human Amniotic Fluid-Derived Mesenchymal Stem Cells by Jingchun Du, Anqi Liu, Rui Zhu, Chengbo Zhou, Heng Su, Guie Xie, Yingshan Deng, Xia Xu

    Published 2019-01-01
    “…AFMSCs primed with IFN-γ highly expressed immunosuppressive molecule IDO1, but IFN-β counteracted the IFN-γ-initiated IDO1 expression. 1-MT (IDO1 inhibitor) decreased TRAIL, but increased IDO1 expression in AFMSCs primed with interferon. …”
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    Article
  8. 1048

    Possibility of using a mouse SCID as a model animal to variola virus for evaluating anti-smallpox drug efficacy by K. A. Titova, Al. A. Sergeev, A. S. Kabanov, L. E. Bulychev, Ar. A. Sergeev, D. O. Galahova, A. S. Zamedyanskaya, L. N. Shishkina, O. S. Taranov, V. V. Omigov, E. L. Zavjalov, A. P. Agafonov, A. N. Sergeev

    Published 2015-12-01
    “…This opens up the prospect of using SCID mice as an animal model for smallpox to develop antiviral drugs intended for people with severe immuno­suppressive states.…”
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    Article
  9. 1049

    Evaluating the use of Uromune® autovaccine in recurrent urinary tract infections: a pilot unicenter retrospective study in Reus, Spain by Simona Iftimie, Paula Ladero-Palacio, Ana F. López-Azcona, Laia Pujol-Galarza, Antoni Pont-Salvadó, Xavier Gabaldó-Barrios, Jorge Joven, Jordi Camps, Antoni Castro, Mercè Pascual-Queralt

    Published 2025-01-01
    “…Regression analysis identified having had a urostomy, chronic kidney disease, and being immunosuppressed as predictors of recurrence. Conclusion Uromune® autovaccine was associated with a significant reduction in the frequency of recurrent UTIs and related hospitalizations, offering substantial relief to patients. …”
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    Article
  10. 1050
  11. 1051

    Fetal Cartilage Progenitor Cells in the Repair of Osteochondral Defects by Bruno C. Menarim, DVM, PhD, Chan Hee Mok, PhD, Kirsten E. Scoggin, PhD, Alexis Gornik, DVM, Emma N. Adam, DVM, PhD, Shavahn C. Loux, PhD, James N. MacLeod, VMD, PhD

    Published 2025-03-01
    “…Osteochondral defects were created in the knee of immunosuppressed rats and were grafted with cell pellets from either equine fetal IZN, equine fetal ANL, adult fibroblasts, or adult chondrocytes, or they were left untreated. …”
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    Article
  12. 1052

    Intestinal obstruction caused by disseminated mycobacterium avium complex disease following solid organ transplantation: a case report by Akane Mita, Sho Nakakubo, Yusuke Nishimura, Hideki Shima, Masaaki Watanabe, Tsuyoshi Shimamura, Satoshi Konno

    Published 2025-01-01
    “…The patient’s outcome emphasizes the need for vigilance in managing long-term immunosuppressed patients, particularly when they present with atypical infections.…”
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    Article
  13. 1053

    Sinomenine attenuates uremia vascular calcification by miR-143-5p by Fengyi Yu, Zhong Peng, Ning Gao, Zixu Tang, Zihao Liao, Song Zhao, Shuzhu Zhong, Gloria Umwiza, Hong Huang, Wei Long, Zhangxiu He

    Published 2025-01-01
    “…Sinomenine exhibited anti-inflammatory and immunosuppressive effects. Objective of this study was to investigate the effect of sinomenine in vascular calcification and its potential molecular mechanism. …”
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    Article
  14. 1054

    Classification of Nanomaterial Drug Delivery Systems for Inflammatory Bowel Disease by Wang H, Zhou F, Shen M, Ma R, Yu Q

    Published 2025-02-01
    “…Lifelong maintenance therapy may thus be needed to manage these symptoms; however, traditional IBD drugs, such as 5-aminosalicylic acid, glucocorticoids, immunosuppressants, and biological agents, are often associated with problems including poor solubility, instability, and ineffective targeting, as well as causing serious side effects in non-target tissues. …”
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    Article
  15. 1055
  16. 1056

    Early, Noninvasive Clinical Indicators of Kidney Prognosis in Primary Nephrotic Syndrome: A Retrospective Exploratory Study by Keiji Fujimoto, Takatoshi Haraguchi, Sho Kumano, Keita Yamazaki, Nobuhiko Miyatake, Kanae Nomura, Kiyotaka Mukai, Kazuaki Okino, Norifumi Hayashi, Hiroki Adachi, Hitoshi Yokoyama, Yasuo Iida, Kengo Furuichi

    Published 2022-01-01
    “…Univariate Cox proportional hazards regression analysis identified clinical parameters in the 2-month period after initiating immunosuppressive therapy (IST); it predicted 40% reduction in the estimated glomerular filtration rate (eGFR) in 36 patients with primary NS. …”
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    Article
  17. 1057

    Identification of tacrolimus-related genes in familial combined hyperlipidemia and development of a diagnostic model using bioinformatics analysis by Yuan Xu, Hongfei He, Haiyang Li

    Published 2025-02-01
    “…Given tacrolimus's immunosuppressive impact, the gene expression matrix data obtained from dataset GSE1010 was submitted to CIBERSORT to assess immune cell infiltration outcomes. …”
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    Article
  18. 1058

    Impact of Cyclosporine A on Cognitive Functions and Neuronal Oxidative Stress, Apoptosis and Inflammatory Markers in Rats by Awyed Batah Almutairi, Abdulaziz Arif A. Alshammari, Arshad Husain Rahmani, Ali Yousif Babiker, Long Chiau Ming, Maha A. Aldubayan, Ahmad H. Alhowail, Vasudevan Mani

    Published 2024-07-01
    “… Cyclosporine A (CYP-A), a potent immunosuppressive agent, significantly impacts organ transplantation and the treatment of autoimmune disorders, and its ability to control autoimmune reactions and prevent organ rejection has made it indispensable in contemporary medicine. …”
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    Article
  19. 1059

    Composite submental flaps in facial reconstructive surgery involving the zygoma and orbit by Usman Khan, Sebastian Haupt, Matthew Rigby, S. Mark Taylor, Martin Corsten, Jonathan Trites

    Published 2020-10-01
    “…A third case was a 75-year-old immunosuppressed male with a 6.5 cm SCC of the right cheek with invasion of the orbit and zygoma following prior resection as well as high dose radiotherapy. …”
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    Article
  20. 1060

    COVID-19 in the years 2020 to 2022 in Germany: effects of comorbidities and co-medications based on a large-scale database analysis by Roland Linder, Jonas Peltner, Anatoli Astvatsatourov, Willy Gomm, Britta Haenisch

    Published 2025-02-01
    “…Immunodeficiencies and use of immunosuppressives were strongest risk modifying factors for hospitalization in both study populations. …”
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    Article