Oncolytic alphavirus-induced extracellular vesicles counteract the immunosuppressive effect of melanoma-derived extracellular vesicles by Darshak K. Bhatt, Annemarie Boerma, Silvina Odete Bustos, Andréia Hanada Otake, Alexis Germán Murillo Carrasco, Patrícia Pintor Reis, Roger Chammas, Toos Daemen, Luciana Nogueira de Sousa Andrade

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Biomimic Nanodrugs Overcome Tumor Immunosuppressive Microenvironment to Enhance Cuproptosis/Chemodynamic‐Induced Cancer Immunotherapy by Hangyi Wu, Xiaoyu Lu, Yuhan Hu, J. Baatarbolat, Zhihao Zhang, Yiping Liang, Youwen Zhang, Ye Liu, Huixia Lv, Xin Jin

“…However, the tumor immunosuppressive microenvironment (TIM) attenuates the efficiency of the immune response. …”
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Modulatory action of Bryonia alba on the immune system in cyclophosphamide induced immunosuppression in BALB/c mice. by Vara Prasad Saka, Godlaveti Vijay Narasimha Kumar, Abanti Goswami, Bharat Kumar Reddy Sanapalli, Pankaj Gupta, Digvijay Verma, Subhash Kaushik

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Strongyloides stercoralis combined with concurrent multiple pathogens infections in an immunosuppressed patient: a case report by Jingchun Fang, Jingchun Fang, Huimin Fang, Huimin Fang, Penghao Guo, Yaqin Peng, Peisong Chen

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Prognostic value of immunosuppression scores in patients with esophageal squamous cell carcinoma: a multicenter study by Shao-jun Xu, Shao-jun Xu, Shao-jun Xu, Yun-fan Luo, Yun-fan Luo, Yun-fan Luo, Jin Huang, Jin Huang, Jin Huang, Jia-hua Tu, Chao Chen, Chao Chen, Chao Chen, Yan-ming Shen, Yan-ming Shen, Yan-ming Shen, Zhao-min Sun, Zhao-min Sun, Zhao-min Sun, Shu-chen Chen, Shu-chen Chen, Shu-chen Chen

“…The cumulative incidence of recurrence (CIR) and the incidence of tumor-related death (CID) were analyzed in various groups. An immunosuppression score (ISS) was developed based on HLA-E expression and NK cell proportion. …”
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A Prospective, Multinational Pharmacoepidemiological Study of Clinical Conversion to Sirolimus Immunosuppression after Renal Transplantation by Bertram L. Kasiske, Bjorn Nashan, Maria Del Carmen Rial, Pablo Raffaele, Graeme Russ, Josep Campistol, Mark D. Pescovitz, Paul A. Keown

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Vascularized Composite Allograft Rejection Is Delayed by Intrajejunal Treatment with Donor Splenocytes without Concomitant Immunosuppressants by Christopher Glenn Wallace, Chia-Hung Yen, Hsiang-Chen Yang, Chun-Yen Lin, Ren-Chin Wu, Wei-Chao Huang, Jeng-Yee Lin, Fu-Chan Wei

“…Treatment significantly increased immunosuppressive IL-10/IL-4/TGF-β production and significantly decreased proinflammatory IFN-γ/TNF-α. …”
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Immunomodulatory Effects of Robinia pseudoacacia Polysaccharides on Live Vaccine against Infectious Bronchitis in Immunosuppressive Chickens by Qiuyan Sun, Fang Li, Caixia Wang, Meiyan Shen

“…In order to investigate the immunomodulatory effect of Robinia pseudoacacia Polysaccharides (RPPS) on vaccine against Infectious Bronchitis (IB) in immunosuppressive chickens, the artificial leukemia chicken model was established and then the IB live vaccine (H120 strain) was immunized. …”
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Disseminated Chickenpox Following Live Varicella Vaccination in a Crohn’s Disease Patient on Combination Immunosuppression by Quintin Solano, Sarah Uttal, Peter D. R. Higgins, Jeffrey A. Berinstein

“…We present a case of a patient with refractory Crohn’s disease (CD) who developed primary varicella (chickenpox) of a vaccine-viral strain after receiving combination immunosuppression with high-dose corticosteroids, tumor necrosis factor inhibitor (TNFi), and a Janus kinase inhibitor (JAKi) in the hospital. …”
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Post Varicella Necrotising Fasciitis Afflicting Upper Limb in Young Child: A Rare Case Report by Swarup Prabhu, Ayjaz Hussain, Tarun Gupta

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Infectious encephalitis diagnosis and treatment in immunosupressed patients: a case report and review of literature by M. Jokubaitis, J. Valaikienė

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Two Patients with Therapy-Resistant Pemphigus Vulgaris and Severe Underlying Disease Showing Good Response to a New IVIg Preparation by Katharina Hogrefe, Julia K. Winkler, Alexander H. Enk

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Predictors of interferon-gamma release assay results and their association with COVID-19 infection outcomes by S.J.W. Kang, G.W. Eather, F. Qureshi, J.R. Scott

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Editorial: Women in renal pharmacology 2023 by Nuria Lloberas, Laure Elens, Brenda de winter

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The Role of Bronchoalveolar Lavage in Therapeutic Antimicrobial Choices for Hematologic Patients with Pulmonary Infiltrates by Filippo Patrucco, Mattia Bellan, Davide Martinotti, Giuseppe Ielo, Paola Rebecca Iovine, Martina Mascheroni, Francesco Todisco, Martina Ubaldi, Nadia Castaldo, Francesco Gavelli, Alberto Fantin

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Multiple Brain Abscesses in a Patient with Myasthenia Gravis – a Case Report by S. Radzevičiūtė, G. Liaudanskytė, I. Baužaitė, N. Balčiūnienė, A. Vaitkus

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The Mechanisms of Systemic Inflammatory and Immunosuppressive Acute-on-Chronic Liver Failure and Application Prospect of Single-Cell Sequencing by Kai Kou, Xiaodong Sun, Guangyao Tian, Yao Zhi, Zhongqi Fan, Guoyue Lv

“…The late stage of ACLF is mainly characterized by immunosuppression. In this process, the dysfunction of monocyte and macrophage is reflected in the downregulation of HLA-DR and upregulation of MER tyrosine kinase (MERTK), which weakens the antigen presentation function and reduces the secretion of inflammatory cytokines. …”
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TUBA1B as a novel prognostic biomarker correlated with immunosuppressive tumor microenvironment and immunotherapy response by Juntao Qi, Juntao Qi, Mingming Zhou, Na Yang, Huiyun Ma, Min He, Gujie Wu, Chang Ge, Liuyin Jin, Lin Cheng, Wei Liao, Hefei Ren, Caiyun Lei

“…Elevated TUBA1B levels are associated with an immunosuppressive tumor microenvironment, impacting cancer progression and treatment outcomes. …”
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KYNU as a Biomarker of Tumor-Associated Macrophages and Correlates with Immunosuppressive Microenvironment and Poor Prognosis in Gastric Cancer by Kaiyu Shen, Binyu Chen, Liu Yang, Wencang Gao

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Pneumocystis Jirovecii Pneumonia in Two Immunosuppressed Non-HIV Infected Patients: A Clinical and Therapeutic Analysis by Li W, Hua M, Guo J, Jia W

Subjects: “…organ transplantation，immunosuppression…”
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