A new paradigm for cancer immunotherapy: targeting immunogenic cell death-related noncoding RNA by Guojuan Sun, Ling He

“…Immunogenic cell death (ICD) can amplify the antitumor immune responses and reverse the immunosuppressive tumor microenvironment, thus increasing the sensitivity of cancer immunotherapy. …”
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Tumor metabolic regulators: key drivers of metabolic reprogramming and the promising targets in cancer therapy by Kun Huang, Ying Han, Yihong Chen, Hong Shen, Shan Zeng, Changjing Cai

“…Metabolic dysregulation creates an immunosuppressive TME, impairing the antitumor immune response. …”
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Mechanism and Treatment Strategy of Osteoporosis after Transplantation by Lei Song, Xu-Biao Xie, Long-Kai Peng, Shao-Jie Yu, Ya-Ting Peng

“…Bone loss after organ transplant is related to adverse effects of immunosuppressants on bone remodeling and bone quality. …”
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High on Cannabis and Calcineurin Inhibitors: A Word of Warning in an Era of Legalized Marijuana by Naomi Hauser, Tanmay Sahai, Rocco Richards, Todd Roberts

“…Tacrolimus, a potent immunosuppressant medication, acts by inhibiting calcineurin, which eventually leads to inhibition of T-cell activation. …”
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Use of Hyaluronic Acid as Adjuvant in Periodontal Therapy and Healing: a Bibliographic Review by Marcelo Fernando Armijos Briones, Cinthya Lisbeth Sinchiguano Moreano, Coralia de los Ángeles Ortega Medina

“…Hyaluronic acid is a natural non-sulfated polysaccharide of the glycosaminoglycan family, it can cause different responses in the body, the high molecular weight has anti-inflammatory, immunosuppressive and healing effects, while the low molecular weight has proinflammatory properties. …”
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Leprosy with Atypical Skin Lesions Masquerading as Relapsing Polychondritis by Punit Pruthi, Hariharan Munganda, Amit Bangia, Uma Rani, Rajesh Budhiraja, Swapnil Brajpuriya

“…Tissue diagnosis should always be attempted whenever possible in patients presenting with autoimmune features, so that inappropriate therapy with immunosuppressants is avoided.…”
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XMRV Discovery and Prostate Cancer-Related Research by David E. Kang, Michael C. Lee, Jaydip Das Gupta, Eric A. Klein, Robert H. Silverman

“…Subsequent investigations in North America, Europe, Asia, and Africa have either observed or failed to detect XMRV in patients (prostate cancer, chronic fatigue syndrome-myalgic encephalomyelitis (CFS-ME), and immunosuppressed with respiratory tract infections) or normal, healthy, control individuals. …”
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Significance of Urinary Proteome Pattern in Renal Allograft Recipients by Sufi M. Suhail

“…Substantial numbers of studies have shown that different renal allograft disease states, both acute and chronic, could portray unique urinary proteome pattern enabling early diagnosis of graft dysfunction and proper manipulation of immunosuppressive strategy that could impact graft prognosis. …”
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Insulin Autoimmune Syndrome: A Systematic Review by MingXu Lin, YuHua Chen, Jie Ning

“…For patients with severe symptoms, available treatments may include drugs that reduce pancreatic insulin secretion (such as somatostatin and diazoxide), immunosuppressants (glucocorticoids, zaprin, and rituximab), and even plasma exchange to remove autoantibodies from the body. …”
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Extensive Longitudinal Transverse Myelitis after Influenza A Virus Infection in a Patient with Systemic Lupus Erythematosus by Suheiry Márquez, Luis M. Vilá

“…This case highlights the importance of early recognition and prompt treatment with immunosuppressive drugs in such cases.…”
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A Case of Superficial Mycoses in a Patient with Systemic Lupus Erythematosus by Li Z, Lu J, Yang Z

“…The fungal infection was further aggravated by the patient’s 10-year history of SLE and long-term immunosuppressive drug therapy. Ultimately, Fungal microscopy and culture results were consistent with superficial mycosis. …”
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Dermatomyositis following resection of thyroid and breast cancer: a case report and literature review by Miaomiao Yang, Jiannan Liu

“…This patient subsequently received systemic immunosuppressant therapy and thus dermatomyositis gradually resolved.ConclusionsA combination of thyroid cancer and breast cancer is thought to be very rare, especially in patients who develop dermatomyositis after thyroidectomy and mastectomy. …”
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Characteristics, pathogenic and therapeutic role of gut microbiota in immunoglobulin A nephropathy by Kaijin Yao, Lingqian Zheng, Wenmin Chen, Yina Xie, Chunling Liao, Tianbiao Zhou

“…Current treatments for IgAN include supportive care and immunosuppressive therapy. A growing number of studies found that the gut microbiota in IgAN was dysregulated. …”
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The Occurrence of Aflatoxins in Date Palm (Phoenix dactylifera L.) Worldwide by Merfat Abdulrahman Almaghrabi

“…Aflatoxins pose serious health hazards to humans’ and animals’ health because of their carcinogenic, mutagenic, and teratogenic properties and their immunosuppressive effects. Aflatoxin contamination in various agricultural commodities has attracted much attention worldwide. …”
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Long-Term Clinical Behavior of Jejunoileal Involvement in Crohn’s Disease by Hugh J Freeman

“…Moreover, pharmacological therapies with corticosteroids and immunosuppressant drugs were rarely successful, with virtually all patients requiring at least one, and usually multiple, intestinal resections. …”
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Treatment of neuro-invasive listeriosis: an overview by P. Gudeikaitė, J. Valaikienė, R. Mameniškienė

“…The most at-risk populations are pregnant women, neonates, people over 65 years of age, and patients with chronic diseases or using immunosuppressive drugs. In case of suspected acute meningitis, encephalitis or meningoencephalitis in these individuals, it must be considered that the pathogen can be Listeria monocytogenes, which is resistant to the therapy of cephalosporins. …”
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Resolved Hepatitis B: Achieved or Imaginary Wellbeing? by S. N. Batskikh

“…Occult HBV infection in PHB individuals can reactivate at background immunosuppressive or chemotherapies. PHB with chronic liver diseases of various aetiology significantly rises the risk of cirrhosis and hepatic cancer. …”
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Predictive role of SLC1A5 in neuroblastoma prognosis and immunotherapy by Jian Cheng, Miaomiao Sun, Xiao Dong, Yang Yang, Xiaohan Qin, Xing Zhou, Yongcheng Fu, Yuanyuan Wang, Jingyue Wang, Da Zhang

“…Immune infiltration analysis revealed a more immunosuppressive tumor microenvironment associated with high SLC1A5 expression. …”
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Corticosteroid use beyond 1-year post heart transplantation is associated with worse outcomes: A contemporary analysis of the ISHLT registry by Abhishek Jaiswal, MD, William L. Baker, Pharm.D, Ashwin Pillai, MD, Michelle Kittleson, MD, PhD, Balaphanidhar Mogga, MD, Zeina Jedeon, MD, Caroline Chen, David A. Baran, MD

“…Introduction: Immunosuppressive drugs ensure graft survival in heart transplantation (HT). …”
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Сhronic relapsing inflammatory optic neuropathy: diagnostic strategies and treatment (literature review) by T.I. Nehrych, M.B. Kopchak, S.Ya. Kyryliuk

“…It is important to identify such patients because the appointment of appropriate immunosuppressive therapy causes remission of the disease.…”
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