Intravenous γ Globulin for Intractable Abdominal Pain due to IgA Vasculitis by George Naifa, George Totikidis, Sonia Alexiadou, Christina Kolona, Elpis Mantadakis

“…Given the toxicity and/or need for long-term administration of other second-line immunosuppressive therapies in corticosteroid-resistant IgA vasculitis, such as rituximab, cyclosporine, cyclophosphamide, azathioprine, or colchicine, we propose that IVIg may be a useful and safe treatment option, although randomized controlled clinical trials are needed in order to clarify its role in the treatment of abdominal pain in IgA vasculitis.…”
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The Origins, Specificity, and Potential Biological Relevance of Human Anti-IgG Hinge Autoantibodies by Randall J. Brezski, David M. Knight, Robert E. Jordan

“…Several biological functions have been attributed to HAH autoantibodies, ranging from house-cleaning functions to an immunosuppressive role to restoring function to cleaved IgGs. …”
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Rapid Growth of Lung Nodules due to Combined Pulmonary Vasculitis, Silicoanthracosis, and Chondrocalcinosis by Wolfgang Jungraithmayr, Stefanos Tzafos, Oliver Distler, Antonios G. A. Kolios, Walter Weder, Daniel Franzen

“…Apart from this, consideration of metastatic disease should be obligatory in patients with a history of cancer at the same time being immunosuppressed.…”
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Severely Disseminated Kaposi Sarcoma after ABO-Incompatible Kidney Transplantation Treated Successfully with Paclitaxel and Gemcitabine Combined with Hemodialysis by Tobias Bomholt, Anders Krarup-Hansen, Martin Egfjord, Søren Schwartz Sørensen, Niels Junker

“…Kaposi Sarcoma (KS) is driven by human herpes virus 8 causing vascular proliferation which is induced by loss of immune function most often due to HIV or immunosuppressants. KS occurs with increased incidence in kidney transplant recipients, but rarely is disseminated. …”
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Muscle-Specific Tyrosine Kinase-Associated Myasthenia Gravis: A Neuromuscular Surprise by Hassam Ali, Rahul Pamarthy, Nayab Ahsan, null WashmaAwan, Shiza Sarfraz

“…It responds inconsistently to steroids, but plasma exchange and immunosuppressive therapies have shown promising results. …”
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Histopathological Study of Cyclosporine Pulmonary Toxicity in Rats by Said Said Elshama, Ayman El-Meghawry EL-Kenawy, Hosam-Eldin Hussein Osman

“…Cyclosporine is considered one of the common worldwide immunosuppressive drugs that are used for allograft rejection prevention. …”
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When thyroid met brain: the enigma of steroid responsive encephalopathy associated with autoimmune thyroiditis a case report by Palash Kotak, Kashish Khurana, Sarang Raut, Saket Satyasham Toshniwal, Sourya Acharya

“…At the same time, other immunosuppressive agents are reserved for non-responders. …”
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Hyper IgG4-Related Disease Presenting with Orbital Tumor and Immune Deficiency by Caroline G. Olson, Nancy Y. Olson

“…The patient was started on prednisone and tried several immunosuppressive medications including mycophenolate mofetil, methotrexate, hydroxychloroquine, and azathioprine with decrease in size of the orbital pseudotumor. …”
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Emerging therapeutics in idiopathic inflammatory myopathy by Shinji Sato

“…Currently, glucocorticoids remain the first line of treatment of IIMs, but in addition to these, several other immunosuppressive agents or intravenous immunoglobulin have been used in a variety of different combinations. …”
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Mycobacterium intracellulare Infection Mimicking Progression of Scleroderma by Simon Krabbe, Merete Engelhart, Sören Thybo, Søren Jacobsen

“…She developed massive inflammatory changes of the cutis, the subcutis, and the muscle fasciae of the right leg, that after several failed attempts of immunosuppressive treatments were found to be caused by Mycobacterium intracellulare. …”
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Hepatic Disorders and COVID-19: From Pathophysiology to Treatment Strategy by Parisa Shiri Aghbash, Hamed Ebrahimzadeh Leylabadlo, Hamidreza Fathi, Mohaddeseh Bahmani, Rojin Chegini, Hossein Bannazadeh Baghi

“…Furthermore, antiviral medications, immunosuppressive drugs after liver transplantation, pre-existing hepatic diseases, and chronic liver diseases such as cirrhosis have also been implicated in SARS-CoV-2-induced liver injury. …”
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The utilization of microbial cell-free DNA next-generation sequencing for the detection of human herpesvirus-8 in a quaternary care center by Rebecca Berger, Jennifer Jacobe, Fernando H. Centeno, Todd Lasco, Mayar Al Mohajer

“…Methods: Between 2017 and 2024, we reviewed the medical charts of 10 immunosuppressed patients at a quaternary care center who had positive HHV8 mcfDNA NGS results. …”
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Structural insights into antibody-based immunotherapy for hepatocellular carcinoma by Masaud Shah, Muhammad Hussain, Hyun Goo Woo

“…Several therapeutic antibodies that counter the immunosuppressive tumor microenvironment have demonstrated efficacy in clinical trials, leading to FDA approvals for advanced HCC treatment. …”
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Cancer in myositis by Albert Selva-O'Callaghan, Maria Terrones-Peinador, Joana Rita Marques-Soares, Albert Gil-Vila

“…There is an intriguing relationship between cancer and myositis. The immunosuppressive agents commonly used to treat myositis patients are known to favor the development of cancer, but this factor does not seem to be the main cause of the association. …”
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Chiral polypeptide hydrogels regulating local immune microenvironment and anti-tumor immune response by Junfeng Ding, Tianran Wang, Zhiqiang Lin, Zhenyu Li, Jiaxuan Yang, Fujiang Li, Yan Rong, Xuesi Chen, Chaoliang He

“…Finally, D-Gel establishes a local chronic inflammatory and immunosuppressive microenvironment and shows insufficient anti-tumor effects. …”
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Self‐Healing COCu‐Tac Hydrogel Enhances iNSCs Transplantation for Spinal Cord Injury by Promoting Mitophagy via the FKBP52/AKT Pathway by Zhenming Tian, Han‐Jian Hu, Chun Cheung Chan, Tian Hu, Chaoyang Cai, Hong Li, Limin Rong, Gang‐Biao Jiang, Bin Liu

“…Tacrolimus, known for its dual role as an immunosuppressant and promoter of neural regeneration, holds the potential for enhancing iNSC transplantation. …”
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Development of biomaterials for bone tissue engineering based on bile acids by Yongjun Liu, Xiaojie Liu, Chang Liu, Wenan Zhang, Ting Shi, Guanying Liu

“…Certain bile acids (BAs) demonstrate significant antioxidant, anti-inflammatory, and immunosuppressive properties, and effectively promote bone and tissue regeneration. …”
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Sustained Remission in Patients with Primary Immune Thrombocytopenia after Romiplostim Tapering and Discontinuation: A Case Series in Real Life Management in Spain by María-Eva Mingot-Castellano, Carlos Grande-García, David Valcárcel-Ferreiras, Clara Conill-Cortés, Loreto de Olivar-Oliver

“…The evidence showing remissions, that is, sustained platelet counts after romiplostim discontinuation, in patients with ITP refractory to immunosuppressive therapy is steadily increasing. However, there is a lack of guidelines or recommendations addressing how and when to taper romiplostim in clinical practice in patients maintaining elevated and stable platelet counts. …”
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Neuromyelitis Optica Spectrum Disease with Positive Autoimmune Indices: A Case Report and Review of the Literature by M. E. Evangelopoulos, G. Koutsis, E. Andreadou, C. Potagas, A. Dimirakopoulos, C. Sfagos

“…Administration of immunosuppressive therapy resulted in gradual improvement of the patient's clinical status and stabilization for five years. …”
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Successful Treatment of Plasma Cell-Rich Acute Rejection Using Pulse Steroid Therapy Alone: A Case Report by Yo Komatsuzaki, Yasuyuki Nakada, Izumi Yamamoto, Mayuko Kawabe, Takafumi Yamakawa, Ai Katsuma, Haruki Katsumata, Aki Mafune, Akimitsu Kobayashi, Yusuke Koike, Hiroki Yamada, Jun Miki, Yudo Tanno, Ichiro Ohkido, Nobuo Tsuboi, Keitaro Yokoyama, Hiroyasu Yamamoto, Takashi Yokoo

“…Despite the recent development of immunosuppressive agents, plasma cell-rich acute rejection (PCAR) has remained refractory to treatment. …”
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