Live Combined Bacillus subtilis and Enterococcus faecium Ameliorate Murine Experimental Colitis by Immunosuppression by S. Chen, Y. Fu, L. L. Liu, W. Gao, Y. L. Liu, S. H. Fei, Y. Tan, K. F. Zou

“…Live combined Bacillus subtilis and Enterococcus faecium ameliorate murine experimental colitis by immunosuppression manifested by downregulation of TLRs, macrophages, Th1, and Th2 but upregulation of Tregs.…”
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Multiple Immunosuppressive Effects of CpG-c41 on Intracellular TLR-Mediated Inflammation by Wancheng Liu, Xuejiao Yang, Ning Wang, Shijun Fan, Yuanfeng Zhu, Xinchuan Zheng, Yan Li

“…We also found evidence that the immunosuppressive effects of CpG-c41 on other intracellular TLRs are mediated by a TLR9-independent mechanism. …”
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Traditional Chinese Medicine Protects against Cytokine Production as the Potential Immunosuppressive Agents in Atherosclerosis by Yan Ren, Wei Qiao, Dongliang Fu, Zhiwei Han, Wei Liu, Weijie Ye, Zunjing Liu

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Immunosuppressive therapy and nutritional diseases of patients after kidney transplantation: a systematic review by Aleksandra Anna Kajdas, Marcin Kleibert, Anne Katrine Normann, Krzysztof Krasuski, Ditte Søndergaard Linde, Dorota Szostak-Węgierek

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Immunomodulatory effects of Lactiplantibacillus plantarum CCFM8661 + stachyose on cyclophosphamide-induced immunosuppression mice by Weiwei Ma, Hang Sun, Lian Lian, Lidong Guo, Yanyan Wang, Lili Huang

“…On days 23 and 24, except for the normal control group, all other groups were intraperitoneally injected with cyclophosphamide (40 mg/kg) to establish an immunosuppressed model. On day 28, 30 minutes after the final administration, the mice were euthanized to collect the thymus, spleen, serum, ileum, and feces for subsequent analysis of immune indicators, intestinal barrier function, serum cytokines, and intestinal microbiota.ResultsThe combination significantly improved immune organ atrophy, restored intestinal morphology, and normalized cytokine levels in immunosuppressed mice, indicating enhanced immune function. …”
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Elevated Incidence of Fractures in Solid-Organ Transplant Recipients on Glucocorticoid-Sparing Immunosuppressive Regimens by B. J. Edwards, A. Desai, J. Tsai, H. Du, G. R. Edwards, A. D. Bunta, A. Hahr, M. Abecassis, S. Sprague

“…The estimated relative risk of fracture was nearly seventeen-times higher in male liver transplant recipients ages 45–64 years compared with the general male population, and comparable to fracture rates on conventional immunosuppressant regimens. Conclusion. We identify a high frequency of fractures in transplant recipients despite limited glucocorticoid use.…”
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GDF15 induces immunosuppression via CD48 on regulatory T cells in hepatocellular carcinoma by Meng Li, Yuan Gao, Wei Zhang, Zhijun Tan, Kuo Zhang, Zhaowei Wang, Lei He, Weina Li, Chuanyang Xu, Jieyu Zhang, Desheng Wang, Kefeng Dou, Ran Zhuang, Boquan Jin, Qiang Hao, Wangqian Zhang, Shuning Wang, Jintao Gu, Lei Shang, Haichuan Su, Yingqi Zhang, Cun Zhang

“…Background A better understanding of the molecular mechanisms that manifest in the immunosuppressive tumor microenvironment (TME) is crucial for developing more efficacious immunotherapies for hepatocellular carcinoma (HCC), which has a poor response to current immunotherapies. …”
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Dexamethasone Provides Effective Immunosuppression for Improved Survival of Retinal Organoids after Epiretinal Transplantation by Bikun Xian, Ziming Luo, Kaijing Li, Kang Li, Mingjun Tang, Runcai Yang, Shoutao Lu, Haijun Zhang, Jian Ge

“…We first compared the immunosuppressive abilities of DEX and RAP in activated microglia in an in vitro setting. …”
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A Case of Pulmonary Infarction Resembling Pneumonia during Immunosuppressive Treatment for Rheumatoid Arthritis by Toshiki Kido, Koichiro Shinoda, Kazuyuki Tobe

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The impact of HPV/HIV co-infection on immunosuppression, HPV genotype, and cervical cancer biomarkers by Terkimbi Dominic Swase, Ilemobayo Victor Fasogbon, Ifie Josiah Eseoghene, Ekom Monday Etukudo, Solomon Adomi Mbina, Chebet Joan, Reuben Samson Dangana, Chinyere Anyanwu, Comfort Danchal Vandu, A. B Agbaje, Tijjani Salihu Shinkafi, Ibrahim Babangida Abubarkar, Patrick Maduabuchi Aja

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Enhanced effect of the immunosuppressive soluble HLA-G2 homodimer by site-specific PEGylation by Chisato Yamada, Kimiko Kuroki, Naoyoshi Maeda, Hiroshi Watanabe, Ami Takahashi, Katsumi Maenaka

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Polarization of ILC2s in Peripheral Blood Might Contribute to Immunosuppressive Microenvironment in Patients with Gastric Cancer by Qingli Bie, Pan Zhang, Zhaoliang Su, Dong Zheng, Xinyu Ying, Yumin Wu, Huijian Yang, Deyu Chen, Shengjun Wang, Huaxi Xu

“…These results suggested that there are polarized ILC2s in gastric cancer patients which might contribute to immunosuppressive microenvironment and closely related to the upregulation of MDSCs and M2 macrophages.…”
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Listeria monocytogenes Meningitis in an Immunosuppressed Patient with Autoimmune Hepatitis and IgG4 Subclass Deficiency by Shahin Gaini

“…Her medical history included immunosuppressive treatment with prednisolone and azathioprine for autoimmune hepatitis. …”
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Efficacy of low-dose rituximab versus immunosuppressants in refractory orbital inflammatory pseudotumors with intracranial extension by Yuyu Li, Mingming Sun, Xintong Xu, Biyue Chen, Xiyun Chen, Yuhang Wang, Quangang Xu, Huanfen Zhou, Shihui Wei

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Systemic Candida parapsilosis Infection Model in Immunosuppressed ICR Mice and Assessing the Antifungal Efficiency of Fluconazole by Yu’e Wu, Fangui Min, Jinchun Pan, Jing Wang, Wen Yuan, Yu Zhang, Ren Huang, Lixin Zhang

“…This study was to establish a systemic C. parapsilosis infection model in immunosuppressed ICR mice induced by cyclophosphamide and evaluate the antifungal efficiency of fluconazole. …”
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Should My Patient with Inflammatory Bowel Disease on Immunosuppressive Therapy be Vaccinated against Influenza Virus? by Neeraj Narula, Deborah LR Yamamura, John K Marshall

“…Crohn’s disease and ulcerative colitis are variants of inflammatory bowel disease (IBD) for which immunosuppressive therapy is often required. Immunosuppressed patients are at increased risk for infections, including vaccine-preventable diseases such as influenza. …”
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Tumor Microenvironment‐Responsive Nanoparticles Enhance IDO1 Blockade Immunotherapy by Remodeling Metabolic Immunosuppression by Mengna Wang, Yuhong Liu, Yanshi Li, Tao Lu, Min Wang, Zhaobo Cheng, Lin Chen, Tongling Wen, Min Pan, Guohua Hu

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Outcomes following immunosuppressive therapy withdrawal after complete renal response in proliferative lupus nephritis by Javier Narváez, Francesca Mitjavila, Joan M Nolla, Paola Vidal-Montal, Montserrat Gomà, Xavier Fulladosa, Olga Capdevila, Joan Torras

“…Objective To investigate the rate and factors influencing renal relapse (RR) in proliferative lupus nephritis (LN) patients who discontinued immunosuppressive therapy (IST), as well as the long-term renal outcomes following RR.Methods Retrospective, single-centre study of biopsy-confirmed LN patients who had received IST for at least 36 months and maintained complete renal response (CRR) for a minimum of 12 months before therapy discontinuation.Results Of a total of 106 patients meeting the inclusion criteria, 76 with proliferative classes were selected for analysis. …”
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A Rapid and Satisfactory Outcome with Combined Immunosuppressive Therapy in Acquired Haemophilia A with Underlying Tuberculosis by G. A. C. Gamakaranage, C. Kulathilake, P. G. N. Nadeeshani, K. H. B. P. Fernandopulle, C. S. Moonesinghe, D. Gunawardena, R. S. Gamage, N. Perera, J. Indrakumar

“…He was treated with both antituberculous and combined-aggressive immunosuppressive therapy which resulted in satisfactory disease remission.…”
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Brd7 loss reawakens dormant metastasis initiating cells in lung by forging an immunosuppressive niche by Jayanta Mondal, Junfeng Zhang, Feng Qing, Shunping Li, Dhiraj Kumar, Jason T. Huse, Filippo G. Giancotti

“…Finally, attenuating this immunosuppressive milieu by neutrophil depletion, neutrophil extracellular trap (NET) inhibition, or immune checkpoint therapy abrogates metastatic outgrowth. …”
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