Resveratrol and its derivates improve inflammatory bowel disease by targeting gut microbiota and inflammatory signaling pathways by Ming Li, Ping Li, Rongxue Tang, Hui Lu

“…Conventional treatments for IBD include antibiotics, immunosuppressive agents, 5-aminosalicylic acid, steroids and surgery, which have high toxic side effects. …”
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A Challenging Case of Multifocal Mycobacterium marinum Osteoarticular Infection in a Patient with Anorexia Nervosa by Katie Sharff, Zaw Min, Nitin Bhanot

“…Disseminated infection due to Mycobacterium marinum is rare but has been described in immunosuppressed and transplant recipients. We describe a case of multifocal osteoarticular involvement by this pathogen in a patient with anorexia nervosa. …”
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Bartonella Infection in Immunocompromised Hosts: Immunology of Vascular Infection and Vasoproliferation by Mosepele Mosepele, Dana Mazo, Jennifer Cohn

“…This paper will discuss Bartonella's manifestations in immunosuppressed patients and will examine Bartonella's interaction with the immune system including its mechanisms of establishing infection and immune escape. …”
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Paroxysmal Amnesia Attacks due to Hashimoto’s Encephalopathy by Pelin Nar Senol, Aylin Bican Demir, Ibrahim Bora, Mustafa Bakar

“…Although symptoms suggest a nonlesional encephalopathy in most of the cases, sometimes the clinical appearance can be subtle and may not respond to immunosuppressants or immunomodulatory agents. Here we report a case who presented with drowsiness and amnestic complaints associated with paroxysmal electroencephalography (EEG) abnormalities which could be treated only with an antiepileptic drug.…”
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Serum glutathione peroxidase-3 concentration at diagnosis as a biomarker for assessing disease activity and damage of antineutrophil cytoplasmic antibody-associated vasculitis at d... by Jihye Chung, Jang Woo Ha, Yong-Beom Park, Yong-Beom Park, Sang-Won Lee, Sang-Won Lee

“…BackgroundIn this study, we investigated whether serum glutathione peroxidase-1 (GPX-3) concentration at diagnosis could be used to assess vasculitis activity and damage at diagnosis in immunosuppressive drug-naïve patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).MethodsWe included 71 immunosuppressive drug-naïve patients newly diagnosed with AAV. …”
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Long-term Results in Children with Henoch-Schönlein Nephritis by Caner ASLAN, Nilufer GOKNAR, Emre KELESOGLU, Diana UCKARDES, Cengiz CANDAN

“…The severe group had higher histopathologic stages compared to the mild group (p=0.022). Immunosuppressive treatments were used in 44.4% of mild cases and 100% of severe cases (p<0.01). …”
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Masquerade Syndrome of Multicentre Primary Central Nervous System Lymphoma by Silvana Guerriero, Ermete Giancipoli, Lorenza Ciracì, Giuseppe Ingravallo, Marcella Prete, Elisabetta Di Leo, Antonietta Cimmino, Nicola Cardascia

“…After one year of steroidal and immunosuppressive therapy, a vitrectomy, and a trabeculectomy for unresponsive bilateral vitreitis and glaucoma, MRI showed a multicentre primary central nervous system lymphoma, which was the underlying cause of the masquerade syndrome. …”
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Herpes Simplex Virus-2 Hepatitis: A Case Report and Review of the Literature by Amna Ahmed, Alejandro Granillo, Ethan Burns, Kerri Glassner, Nishath Naseem, Christopher Force, Suzanne M. Crumley, Ashley Drews

“…Herpes simplex virus (HSV) is a rare cause of hepatitis in pregnancy and the chronically immunosuppressed, with a high propensity to progress to acute liver failure (ALF) and death. …”
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Chronic Infection with Hidden Malignancy Mimicking the Clinical Presentation of an Autoimmune Disease by Ammar Bakhsh, Khalil Miyajan, Abdulghani Sadaqa, Amer Eisa, Ghali Faidah, Hani Almoallim

“…Clinicians should look carefully for hidden infections and/or malignancies in patients lacking response while on immunosuppressive therapy for autoimmune disease.…”
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A case of mitral valve plastics in the early postoperative period after orthotopic heart transplantation by B.M. Todurov, G.I. Kovtun, O.O. Samchuk, S.O. Sheludko, I.M. Kuzmich, O.M. Druzhyna, H.Yu. Melnyk

“…Despite the constant improvement of the technique of this operation and the emergence of new protocols of immunosuppressive therapy, one of the main problems in the development of heart transplantation in Ukraine is a limited donor pool. …”
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Features of pregnancy after simultaneous pancreas-kidney transplantation in patient with type 1 diabetes mellitus. Case report by Madina I. Yevloyeva, Darya U. Savitskaya, Anastasia S. Severina, Minara S. Shamkhalova, Natalia P. Trubitsyna, Marina V. Shestakova

“…These risks are significantly reduced with pregnancy planning, regular monitoring of the woman and fetus with timely correction of immunosuppressive therapy, maintenance of target blood pressure and glycemia, selection of optimal timing and method of delivery. …”
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Steroid Avoidance in Liver Transplantation by José Oberholzer, Mohammed Al-Saghier, Norman M Kneteman

“…Steroids may also exacerbate problems that existed before surgery, including malignancy, hepatitis B and hepatitis C. New, powerful immunosuppressants have allowed steroid use to be reduced or avoided altogether, but use of these regimens is not simple and may be associated with late acute rejection and recurrence of autoimmune disease. …”
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Sclerosing Mesenteritis as a Cause of Abdominal Mass and Discomfort in an Elderly Patient: A Case Report and Literature Review by Farzana Nawaz Ali, Sidra Ishaque, Bushra Jamil, Nasir-Ud-Din, Muhammad Idris

“…The patient's symptoms responded to a combination of immunosuppressive drugs, with no interval change in the size of the mass on radiological examination after fifteen months.…”
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Treatment of Immunocompromised, Critically Ill Patients with Influenza A H1N1 Infection with a Combination of Oseltamivir, Amantadine, and Zanamivir by Wouter J. Meijer, Wiete Kromdijk, Marcel P. H. van den Broek, Pieter-Jan A. Haas, Monique C. Minnema, Charles A. Boucher, Dylan W. de Lange, Annemarie M. J. Wensing

“…We report on two critically ill patients on immunosuppressive medication with influenza pneumonia. …”
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Polyarteritis Nodosa Presenting as Digital Gangrene and Breast Lesion following Exposure to Silicone Breast Implants by Yamen Homsi, John Andrew Carlson, Samer Homsi

“…While the pathogenesis of idiopathic PAN is not known yet, responsiveness to immunosuppressive therapy may suggest an immunologic mechanism. …”
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Review of Current First-Line Pharmacotherapy Strategies for Thyroid Eye Disease by Julia Ryniecka, Maciej Wojszczyk, Damian Zys, Piotr Pasek, Julia Kulbacka, Michalina Wójcikiewicz, Marta Chuncia-Ileczko, Julia Kacperczyk, Filip Arczewski, Karol Dziedzic

“…Glucocorticoids (GCs), particularly in intravenous (IV) regimens, remain the first-line treatment due to their strong anti-inflammatory and immunosuppressive effects. This paper focuses on the efficacy, protocols, and safety profiles of selenium supplementation and glucocorticoid therapy, emphasizing its central role in TED management. …”
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New Coronavirus Infection (COVID-19) and Digestive System by V. T. Ivashkin, A. A. Sheptulin, O. Yu. Zolnikova, A. V. Okhlobystin, E. A. Poluektova, A. S. Trukhmanov, E. N. Shirokova, M. I. Gonik, N. I. Trofimivskaya

“…Patients with chronic inflammatory bowel diseases receiving immunosuppressive therapy are at elevated risk of severe COVID-19 progression. …”
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Combination of rapamycin and adipose-derived mesenchymal stromal cells enhances therapeutic potential for osteoarthritis by Damien Veret, Gautier Tejedor, Esther Perez, Alison Chomette, Maylis Farno, Rosanna Ferreira-Lopez, Louis Dagneaux, Yves-Marie Pers, Christian Jorgsensen, Claire Gondeau, Jean-Marc Brondello

“…In addition, rapamycin improved AD-MSC immunoregulatory functions by promoting the expression of immunosuppressive factors, such as IDO1, PTGS2 and also CD274 (encoding PD-L1). …”
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Evaluation of efficacy and safety of generic tacrolimus (Suprotac®) compared to reference tacrolimus (Prograf^®) in kidney transplantation: a phase IV study by Behzad Einollahi, Mohsen Nafar, Mohammad Javanbakht, Amirhesam Alirezaei, Jalal Azmandian, Abbas Etminan, Mohammad Reza Ardalan, Jalal Etemadi, Roghayeh Akbari, Vahid Pourfarziani, Seyed Sadraddin Rasi Hashemi, Seyed Maryam Rahbar, Shahrzad Shahidi, Javid Safa, Hamid Tayyebi Khosroshahi, Sima Abedi Azar, Shahrzad Ossareh, Abdolamir Atapour, Bahareh Marghoob, Fatemeh Nazemian, Hamidreza Kafi, Araz Sabzvari

“… Background Transplant recipients are given an immunosuppressive regimen such as tacrolimus to prevent organ rejection. …”
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Transfusion-transmitted hepatitis E by LI Baixun, LIU Tianxu, HUANG Liqin, DANG Yingnan, WANG Lin

“…It has a higher mortality rate among immunosuppressed patients and pregnant women infected with HEV. …”
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