Liver transplantation in glycogen storage disease type III: A case‐series by Simon Gay, Adrien Bigot, Louis d'Alteroche, Fanny Dujardin, Gaëlle Fromont‐Hankard, Nathalie Tressel, Ephrem Salame, François Maillot

“…Post‐LT outcome was positive for all three GSD III patients, with significant improvement in liver function and no complications related to immunosuppression. Long‐term hepatic monitoring is essential for early detection of complications such as cirrhosis and HCC. …”
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Clinical Recommendations of the Russian Gastroenterological Association on Diagnosis and Treatment of Infectious Esophagitis by V. T. Ivashkin, N. D. Yuschuk, I. V. Maev, A. S. Trukhmanov, O. A. Storonova, A. A. Makushina, S. S. Pirogov, O. V. Zayratyants, O. P. Alekseeva, D. N. Andreyev, T. L. Lapina, A. V. Tkachev, Yu. P. Uspenskiy, A. A. Sheptulin

“…Diagnosis of infectious esophagitis capitalises on the clinical picture (odynophagia, dysphagia), presence of immunosuppression, endoscopic and histological evidence. …”
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Dissecting macrophage heterogeneity and kaempferol in lung adenocarcinoma: a single-cell transcriptomic approach and network pharmacology by Laiyi Wan, Wentao Hao, Leilei Li, Lin Wang, Yanzheng Song

“…Conclusions This study delineates the diverse macrophage landscape in LUAD and suggests a pivotal role for STAT1 in TAM-mediated immunosuppression. Kaempferol, identified from TCM, emerges as an influential agent capable of altering TAM polarization, potentially enhancing anti-tumoral immunity. …”
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Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization by Brenden N Moeun, Florent Lemaire, Alexandra M Smink, Hamid Ebrahimi Orimi, Richard L Leask, Paul de Vos, Corinne A Hoesli

“…Islet transplantation and more recently stem cell-derived islets were shown to successfully re-establish glycemic control in people with type 1 diabetes under immunosuppression. These results were achieved through intraportal infusion which leads to early graft losses and limits the capacity to contain and retrieve implanted cells in case of adverse events. …”
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CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria by Akinsegun Akinbami, Adedoyin Dosunmu, Adewumi Adediran, Sarah Ajibola, Olajumoke Oshinaike, Kikelomo Wright, Olanrewaju Arogundade

“…CD4 count measures the degree of immunosuppression in HIV-positive patients. It is also used in deciding when to commence therapy, in staging the disease, and in determining treatment failure. …”
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Etiological, Clinical, and Epidemiological Characteristics of Acute Viral Gastroenteritis in an Adult Population in a Tertiary Level Hospital in Spain by Sara Herranz-Ulldemolins, Anna Sellarès-Crous, Miriam J. Álvarez-Martínez, M. Eugenia Valls, Marta Aldea Novo, Anna Vilella Morató, Laura Rodriguez, Mireia Navarro, Roser Vendrell, Josep Barrachina, Miguel J. Martínez, M. Ángeles Marcos

“…Mortality and hospitalization rates were high in patients with higher comorbidity indices, mainly in individuals with immunosuppression. Conclusions Viruses are an important cause of acute gastroenteritis in adults presenting for medical consultation. …”
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Taurine inhibits acute ammonia-induced oxidative stress, immune response, and apoptosis of large yellow croaker (Larimichthys crocea) during keep-live transport by Xin Zhao, Zhenkun Xu, Jun Mei, Jing Xie

“…SOD and GPx activities increased from 3.47 to 13.23 (AM group) to 9.4 and 55.48 (50TAU + AM group), immunosuppression (lysozyme activity increased). In conclusion, taurine may alleviate the adverse effects of ammonia stress on fish physiology. …”
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Lactobacillus gasseri LGV03-derived indole-3-lactic acid ameliorates immune response by activating aryl hydrocarbon receptor by Zikang Zhang, Kangdi Zheng, Zhao Zhang, Longbin Cao, Lizhu Lin, Weimin Sun, Feng Qiu

“…Moreover, the transcriptome sequencing results indicated L. gasseri LGV03 might alleviate vinorelbine-induced immunosuppression in zebrafish. Non-targeted detection and analysis revealed that indole derivatives including phenylacetaldehyde, 3-phenyllactic acid, N-acetylserotonin and indole-3-lactic acid were significantly increased in the lysate and supernatant of L. gasseri LGV03. …”
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Efficacy of adalimumab in pediatric non-infectious uveitis with and without anterior segment inflammation by Chunbo Zhang, Xiaorong Xue, Jinan Xiao, Qiongge Li, Yuyao Zhai, Ying Chen

“…Secondary outcomes including best-corrected visual acuity (BCVA), inflammation parameters [anterior chamber cell (ACC), vitreous haze (VH)], retinal nerve fiber layer (RNFL) thickness, fluorescein angiography (FA) scores, as well as systemic immunosuppression therapy (IMT) and glucocorticoid load, were assessed. …”
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Consequences of the Lack of CD73 and Prostatic Acid Phosphatase in the Lymphoid Organs by Gennady G. Yegutkin, Kaisa Auvinen, Marika Karikoski, Pia Rantakari, Heidi Gerke, Kati Elima, Mikael Maksimow, Ileana B. Quintero, Pirkko Vihko, Marko Salmi, Sirpa Jalkanen

“…CD73, ecto-5′-nucleotidase, is the key enzyme catalyzing the conversion of extracellular AMP to adenosine that controls vascular permeability and immunosuppression. Also prostatic acid phosphatase (PAP) possesses ecto-5′-nucleotidase/AMPase activity and is present in leukocytes. …”
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Low regulatory T-cells frequency is associated with graft rejection after small bowel transplantation: Clinical and experimental evidence. by Rodrigo Papa-Gobbi, Pablo Stringa, Maria Virginia Gentilini, Ivana Ivanoff, Mariana Machuca, Nidia Monserrat Arreola, Javier Serradilla, Karla Estefanía-Fernández, Paloma Talayero, María Velayos, Elena Sánchez-Zapardiel, Gabriel Gondolesi, Ane Andrés-Moreno, Martin Rumbo, Francisco Hernández-Oliveros

“…Experimental allogenic-heterotopic small bowel transplantation was performed in rats and animals divided into 3 groups: non-immunosuppressant treatment, rapamycin (2 mg/kg), and tacrolimus (0.6 mg/kg) treatment. …”
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Methicillin-Resistant Staphylococcus aureus Infections in Human Immunodeficiency Virus-Infected Children and Adolescents by George K. Siberry, Toni Frederick, Patricia Emmanuel, Mary E. Paul, Beverly Bohannon, Travis Wheeling, Theresa Barton, Mobeen H. Rathore, Kenneth L. Dominguez

“…Geographic location, black race, and increased VL, but not immunosuppression, were independently associated with MRSA risk.…”
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Physician characteristics associated with the referral from general practitioners to dental surgeons and proposal for a referral letter template endorsed by dental surgeons in Fran... by Matthias Lamauviniere, Jan Chrusciel, Cassandre Finot, Adrien Basset, Maximillien Graftieaux, Aline Ohl-Hurtaud, Stéphane Sanchez

“…Standardized referral letters could include the list of items for which interest was confirmed by dental surgeons (including presence of diabetes, immunosuppressants and anticoagulants or antiplatelet agents).…”
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Macrophage Activities in Myocardial Infarction and Heart Failure by Sophia Esi Duncan, Shan Gao, Michael Sarhene, Joel Wake Coffie, Deng Linhua, Xingru Bao, Zhang Jing, Sheng Li, Rui Guo, Jing Su, Guanwei Fan

“…Also, though inflammation is as a result of adverse HF in patients, but despite the fact that broad immunosuppression therapeutic target has been used in various clinical trials, no positive results have showed up, but rather, the focus on proinflammatory cytokines has proved more benefits in patients with HF. …”
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An adenoviral vector encoding an inflammation-inducible antagonist, HMGB1 Box A, as a novel therapeutic approach to inflammatory diseases by Kari Ann Shirey, John Joseph, Lynda Coughlan, Haye Nijhuis, Alan W. Varley, Jorge C. G. Blanco, Stefanie N. Vogel

“…The recombinant protein would be produced and released only in the presence of the inciting stimulus, avoiding immunosuppression or other unwanted side effects that may occur when treating infectious diseases with anti-inflammatory drugs. …”
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Brincidofovir Use after Foscarnet Crystal Nephropathy in a Kidney Transplant Recipient with Multiresistant Cytomegalovirus Infection by Romain Vial, Christine Zandotti, Sophie Alain, Alexandre Decourt, Noémie Jourde-Chiche, Raj Purgus, Charleric Bornet, Laurent Daniel, Valérie Moal, Tristan Legris

“…Despite a large decrease in immunosuppression, CMV disease was not controlled and a salvage therapy with Brincidofovir (BCV), which is an oral lipid conjugate of cidofovir with limited nephrotoxicity, was attempted. …”
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Persistent Mortality Risk From Device-related Healthcare-associated Infection in Kidney Transplant Recipients Despite Multifaceted Interventions Action Calls for a Zero-tolerance P... by Maria Bethânia Peruzzo, MD, Luana Oliveira Calegari, MSc, Renato Demarchi Foresto, MD, PhD, Helio Tedesco-Silva, MD, PhD, José Medina Pestana, MD, PhD, Lúcio Requião-Moura, MD, PhD

“…Additional variables associated with increased risk of death included age (HR, 1.03; P < 0.001), baseline immunosuppression (HR based on mycophenolate versus others 0.74; P = 0.02), time since transplantation (HR, 1.003; P < 0.001), platelet count at ICU admission (HR, 0.998; P < 0.001), and sepsis as the reason for ICU admission (HR, 1.67; P < 0.001). …”
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A meta-analysis of whole blood transcriptome reveals genes associated with increased neutrophil activity and T cell suppression in sepsis by T. N. Shruthi, Anbazhagan Kolandaswamy, Prabakara Somanna

“…Dysregulation of immune response, imbalance between pro-inflammatory and anti-inflammatory response, apoptosis, and anti-apoptotic genes were found to be associated with immunosuppression and increased inflammatory reaction during sepsis. …”
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Antifungal efficacy of chitosan-mediated fenugreek nanocomposite incorporated in tissue conditioner by Mohika Damle, Ponsekar Abraham Anandapandian, B. Eswaran, Swapnaneel Pradhan, Silvin Joe C J, Shreyas Dhumke

“…Introduction: The rough surface of dentures, coupled with xerostomia and immunosuppression, fosters microbial growth and colonization, with Candida albicans being a primary culprit. …”
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Development of a prognostic model based on four genes related to exhausted CD8+ T cell in triple-negative breast cancer patients: a comprehensive analysis integrating scRNA-seq and... by Yulin Shi, Yang Yu, Jiahan Zhao, Linan Huang, Qingyang Wang, Qi Sun, Lijuan Liu, Changgang Sun

“…T-cell exhaustion (TEX) is a significant risk factor for tumor immunosuppression and invasion. Although improving TEX and enhancing effector function are promising strategies for strengthening immunotherapy, their role in the pathogenesis of TNBC remains unclear. …”
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