Listeria monocytogenes Meningoencephalitis and Cerebral Abscess in a Heart Transplant Recipient by Paul C. Adjei

“…Prior to presentation, he had low-level cytomegalovirus (CMV) viremia for two straight weeks. Given his immunosuppression, diarrhea, and low-level CMV viremia, he was presumed to have cytomegalovirus and/or C. difficile colitis and treated empirically for both on hospital day one. …”
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Transient Complete Recovery of Chronic Refractory Idiopathic Thrombocytopenic Purpura after Treatment with Monoclonal Antibody Targeting SARS-CoV-2 Spike Protein by Pooja Gogia, Yiqing Xu

“…Therapy for ITP relies on competing and inhibiting the autoantibody binding and destruction (intravenous immunoglobulin and anti-D immunoglobulin and spleen tyrosine kinase (Syk) inhibitor fostamatinib), augmenting platelet production (thrombopoietin receptor agonists), immunosuppression to reduce the autoantibody production, as well as splenectomy. …”
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Rare diagnosis of an Epstein-Barr virus-positive extracavitary/solid variant of primary effusion lymphoma by duodenal endoscopic biopsy in a human immunodeficiency virus-seronegati... by Beril Guler, Guven Cetin

“…Virus-associated lymphoproliferative disorders should be considered in the differential diagnosis of patients without a history of immunosuppression or HIV infection.…”
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Belatacept and regulatory T cells in transplantation: synergistic strategies for immune tolerance and graft survival by Gil-Ran Kim, Kyung-Ho Nam, Je-Min Choi

“…Additionally, it discusses the potential benefits of combining therapies that boost Treg cells with belatacept to increase the effectiveness of immunosuppression and improve graft outcomes.…”
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Klebsiella ozaenae Bacteremia in a Kidney Transplant Recipient by Shree Kumar, Talal Alfaadhel, Meteb M. AlBugami

“…We report a 73-year-old patient, with a history of kidney transplant for 38 years on minimum immunosuppression, who presented with high-grade fever and gastrointestinal symptoms. …”
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Tumor-Related Exosomes Contribute to Tumor-Promoting Microenvironment: An Immunological Perspective by Wuzhen Chen, Jingxin Jiang, Wenjie Xia, Jian Huang

“…In this review, we focus on the TEX-induced immunosuppression and microenvironment change. Based on the truth that TEXs play crucial roles in suppressing the immune system, studies on modification of exosomes as immunotherapy strategies will also be discussed.…”
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Effects of macrophages in OSCC progression by Xiaodan Dong, Xiaodan Dong, Chunling Dong, Bo Li

“…Macrophages are crucial immune cells within the tumor microenvironment (TME), involved in regulating tumor proliferation, invasion, metastasis, ECM remodeling, angiogenesis, and immunosuppression. Although more and more experimental evidence and clinical data indicate that macrophages are involved in the onset and progression of oral squamous cell carcinoma (OSCC), the exact pathogenesis of OSCC associated with macrophages has not been fully elucidated. …”
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Autologous Cord Blood Therapy for Infantile Cerebral Palsy: From Bench to Bedside by A. Jensen

“…Particularly, since the first published double-blind randomized placebo-controlled trial in a paradigm using allogeneic cord blood and erythropoietin to treat cerebral palsy under immunosuppression showed beneficial therapeutic effects in infantile cerebral palsy, long-held doubts about the efficacy of this new cell therapy are dispelled and a revision of therapeutic views upon an ailment, for which there is no cure at present, is warranted. …”
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Fulminant Mucormycosis Involving Paranasal Sinuses: A Rare Case Report by Komali Garlapati, Sunanda Chavva, Rahul Marshal Vaddeswarupu, Jyotsna Surampudi

“…Common predisposing factors include diabetes mellitus and immunosuppression. The infection begins in the nose and paranasal sinuses due to inhalation of fungal spores. …”
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A Case of an Acquired Factor VIII Inhibitor Complicated by Multiple Treatment-Related Opportunistic Infections and Review of the Literature by Anna L. Hutchinson, Yi Ling Tan, Giselle Kidson-Gerber

“…It also raises the issue of routine prophylaxis for immunosuppression in nonmalignant conditions, which will become a common dilemma with the expanding indications for rituximab use.…”
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Hemorrhagic Cystitis due to BK Reactivation in a Young Female Treated for Hodgkin-Disease by R. Le Calloch, J. C. Ianotto, C. Berthou, A. Tempescul

“…Reactivation of BKV occurs in individuals with severe immunosuppression during HIV infections, transplantation or, exceptionally, after classical chemotherapy. …”
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Microscopic Polyangiitis with Pulmonary Fibrosis: An Often-Recognized Manifestation of the Disease by Liam M. Clifford, Jamma Li, Christopher J. Renaud, Suran L. Fernando

“…Both patients responded well to immunosuppressive treatment; however, pulmonary fibrosis and COPD were refractory to immunosuppression. …”
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Control of Cross Talk between Angiogenesis and Inflammation by Mesenchymal Stem Cells for the Treatment of Ocular Surface Diseases by Fei Li, Shao-zhen Zhao

“…Although great progress has been achieved, healing of severe ocular surface injury and immunosuppression of corneal transplantation are the most difficult and challenging step in the treatment of ocular surface disorders. …”
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Aggressive Cardiac Involvement in Systemic Lupus Erythematosus: A Case Report and a Comprehensive Literature Review by Reza Ashrafi, Pankaj Garg, Ewan McKay, John Gosney, Som Chuah, Gershan Davis

“…Treatment comprised of high-level immunosuppression.…”
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A Rare Sequela of Acute Disseminated Encephalomyelitis by Vijay Kodadhala, Saravana Devulapalli, Mohankumar Kurukumbi, Annapurni Jayam-Trouth

“…Our case is unique, as acute disseminated encephalomyelitis occurred in a 34-year-old which was poorly responsive to immunosuppression resulting in severe disability.…”
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The Conundrum of Septic Shock Imitators in Patients with Hematologic Cancers: Case Presentation and Possible Differential Diagnoses by Giorgio Berlot, Giulia Moratelli, Martina Tarchini, Katiuscia Battaglia, Paolo Grassi, Nadia Zarrillo, Vincenzo Colella, Rossana Bussani

“…In this article, the mimickers of septic shock are reviewed and discussed, as some of them require an aggressive immunosuppression instead of the recommended treatment for septic shock.…”
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Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids, with Cranial and Caudal Extension by Mahmood Mubasher, Aseel Sukik, Ahmed Hassan El Beltagi, Ali Rahil

“…Our report addresses the radiological and clinical pattern of a case of CLIPPERS rhombencephalitis, with added superior and inferior extension to involve the brain and spinal cord, which is to emphasize the importance of raising the awareness of this disease and the combined role of radiologist and physicians for the diagnosis of this potentially treatable entity, responsive to glucocorticosteroid immunosuppression.…”
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Improving the Safety of Tolerance Induction: Chimerism and Cellular Co-Treatment Strategies Applied to Vascularized Composite Allografts by Wei-Chao Huang, Jeng-Yee Lin, Christopher Glenn Wallace, Fu-Chan Wei, Shuen-Kuei Liao

“…Although vascularized composite allografts (VCAs) have been performed clinically for a variety of indications, potential complications from long-term immunosuppression and graft-versus-host disease remain important barriers to widespread applications. …”
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Autoimmune Hepatitis—Immunologically Triggered Liver Pathogenesis—Diagnostic and Therapeutic Strategies by Elisabeth Sucher, Robert Sucher, Tanja Gradistanac, Gerald Brandacher, Stefan Schneeberger, Thomas Berg

“…AIH responds favorably to steroids and pharmacologic immunosuppression, and liver transplantation is only necessary in cases with acute liver failure or end-stage liver cirrhosis. …”
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The Dendritic Cell-Regulatory T Lymphocyte Crosstalk Contributes to Tumor-Induced Tolerance by Nona Janikashvili, Bernard Bonnotte, Emmanuel Katsanis, Nicolas Larmonier

“…Regulatory T lymphocytes (Treg) and tolerogenic dendritic cells play essential roles in the establishment and persistence of cancer-induced immunosuppression. Differentiating dendritic cells (DCs) exposed to tumor-derived factors may be arrested at an immature stage becoming inept at initiating immune responses and may induce effector T-cell anergy or deletion. …”
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