Mast Cells Exert Anti-Inflammatory Effects in an IL10−/− Model of Spontaneous Colitis by E. M. Lennon, L. B. Borst, L. L. Edwards, A. J. Moeser

“…Mast cells are well established as divergent modulators of inflammation and immunosuppression, but their role in inflammatory bowel disease (IBD) remains to be fully defined. …”
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Rabies Disease and Prophylaxis Knowledge Among Turkish Medical Students: Insights from a Cross-Sectional Study by Vasfiye Demir Pervane, Pakize Gamze Erten Bucaktepe, Fatma Meral İnce, Dicle Demir, Simanur Koç

“…Pregnancy (45.2%), being >65 years of age, having a chronic disease, and being immunosuppressed were indications for rabies vaccine, with rates between 31.4 and 37.4%. …”
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The Regulation Effect of α7nAChRs and M1AChRs on Inflammation and Immunity in Sepsis by Song Hu, Yundong Wang, Hongbing Li

“…The inflammatory storm in the early stage and immunosuppression in the late stage are responsible for the high mortality rates and multiple organ dysfunction in sepsis. …”
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Protracted Hypocalcemia following 3.5 Parathyroidectomy in a Kidney Pancreas Recipient with a History of Robotic-Assisted Roux-en-Y Gastric Bypass by Hugo Bonatti, Naureen Iqbal, Catherine Kling, Willie Melvin, James Broome

“…Alternative bariatric procedures such as sleeve gastrectomy may be more suitable for patients with renal failure or organ transplants in whom adequate absorption of vitamins, minerals, and drugs such as immunosuppressants is essential.…”
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Identification of an Autophagy-Related Signature Based on Whole Bone Marrow Sequencing for the Prognosis and Immune Microenvironment Characterization of Multiple Myeloma by Licheng Li, Ting Chen, Jishi Wang, Mengxing Li, Qinshan Li

“…Immune infiltration of tumor cells resulted in the formation of a strong immunosuppressive microenvironment in high-risk patients. …”
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Cumulative incidence and risk of infection in patients with rheumatoid arthritis treated with janus kinase inhibitors: A systematic review and meta-analysis. by Konstantinos Ouranos, Diana V Avila, Evangelia K Mylona, Athanasios Vassilopoulos, Stephanos Vassilopoulos, Fadi Shehadeh, Eleftherios Mylonakis

“…Patients with rheumatoid arthritis (RA) who receive immunosuppressive medications have a heightened risk of infection. …”
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Successful Treatment of Plasma Cell-Rich Acute Rejection Using Bortezomib: A Case Report by Sara Hashemi, Reut Hod-Dvorai, Rebecca Tong, Liye Suo

“…Then, the patient was given one cycle of bortezomib with a total of four subcutaneous injections and continued immunosuppressants of tacrolimus, mycophenolate mofetil, and prednisone. …”
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Humoral and Cellular Immune Regulation in Albino Rat Exposed to Glyphosate and Aluminum Phosphide by Ujuamala Ezeani, Onyemaechi Afonne, Michael Ezeani

“…Additionally, there was a notable reduction in CD4+ levels at the second and third months post-exposure (p=0.001 and p<0.001, respectively).Conclusion: This study identified a deregulation of the immune system characterized by a progressive immunosuppression of CD4 T cell counts, indicating a down regulation of antibody-mediated (humoral) immune responses alongside an up regulation of cytotoxic T cells. …”
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Clinical features, treatment, and prognosis of secukinumab-induced inflammatory bowel disease by Ronghui Li, Haibo Lei, Chunjiang Wang, Xiang Liu

“…Patients who do not respond or experience a relapse should be considered for immunosuppressive therapy.…”
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Integrative analysis of Ewing’s sarcoma reveals that the MIF-CD74 axis is a target for immunotherapy by Fangzhou He, Jiuhui Xu, Fanwei Zeng, Boyang Wang, Yi Yang, Jie Xu, Xin Sun, Tingting Ren, Xiaodong Tang

“…Results EwS is infiltrated by immunosuppressive myeloid populations, T and B lymphocytes, and natural killer cells. …”
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Challenges in Diagnosis and Management of SLE in Africa: An Online Survey by Farhanah Paruk, Dzifa Dey, Anisa Mosam, Oluwaytoyin Amira Christina, Mohammed Tikly

“…Glucocorticoids and antimalarials were readily available across all regions, with variable availability of immunosuppressants from 93.7% for methotrexate to 65% for calcineurin inhibitors and only 58.4% for the biologic rituximab. …”
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APLASTIC SYNDROME IN A PREGNANT WOMAN ON THE BACKGROUND OF COVID-19: A CLINICAL CASE by Индира Венеровна Сахаутдинова, Ирина Борисовна Фаткуллина, Ирина Робинзоновна Рахматуллина, Игорь Сергеевич Засядкин, Анна Юрьевна Лазарева

“…Further, aplastic syndrome was diagnosed, which developed against the background of pregnancy and infectious complications. Antibacterial, immunosuppressive, and hemotransfusion therapy were performed. …”
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Marek's disease virus-1 unique gene LORF1 is involved in viral replication and MDV-1/Md5-induced atrophy of the bursa of Fabricius. by Chenyi Bao, Jun Chu, Qi Gao, Shasha Yang, Xiaoyu Gao, Wenwen Chen, Fuchun Yang, Fei Jiang, Chenxi Tong, Mingyi Lei, Linlin Jiao, Jitong Li, Kexin Wei, Xue Lian, Kai Li, Suresh Kumar Tikoo, Nikolaus Osterrieder, Lorne A Babiuk, Yufeng Li, Yong-Sam Jung, Yingjuan Qian

“…Marek's disease virus (MDV), an alphaherpesvirus, causes severe immunosuppression and T cell lymphomas in chickens, known as Marek's disease (MD), an economically important poultry disease primarily controlled by vaccination. …”
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Treatment of Multiple Sclerosis with Cladribine Tablets: Literature Review and the Guidance of the Lithuanian Association of Neurologists by R. Kizlaitienė, D. Mickevičienė, L. Malcienė, N. Giedraitienė, R. Balnytė, D. Jatužis

“…This makes cladribine convenient for patients with multiple comorbidities, difficulties in adhering to their prescribed treatment regimen, those planning a pregnancy, or those for whom long-term immunosuppression is undesirable. Cladribine tablets are denoted by good safety characteristics, with the most prominent adverse effect being lymphopenia, which does not lead to an increased risk of infections other than Herpes zoster. …”
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Breaking the shield of solid tumors: a combined approach for enhanced efficacy of CAR-T cells by Marat Khaliulin, Aygul Valiullina, Alexey Petukhov, Youyong Yuan, Sheila Spada, Emil Bulatov

“…Solid tumors exhibit antigenic diversity and an immunosuppressive microenvironment, which presents a challenge for immune cells attempting to penetrate the tumor. …”
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Endometrial Regenerative Cell-Derived Conditioned Medium Alleviates Experimental Colitis by Chenglu Sun, Jingpeng Hao, Hong Qin, Yanglin Zhu, Xiang Li, Baoren Zhang, Yafei Qin, Guangming Li, Hongda Wang, Hao Wang

“…Endometrial regenerative cells (ERCs) have been shown to exert immunosuppressive effects in different models of inflammation, and stem cell-derived conditioned media (CM) have advantages over cell therapy in terms of easy access and direct action. …”
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The effect of the use of omeprazole versus famotidine on the kidney transplant function: a randomized controlled study by Miłosz Miedziaszczyk, Marek Karczewski, Ilona Idasiak-Piechocka

“…A randomized study was conducted in 24 adult patients with stable kidney transplant function who received a standard triple immunosuppression regimen. Patients were assigned to the group I (n = 12) additionally receiving omeprazole (20 mg) or the group II (n = 12) receiving famotidine (20 mg). …”
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CD3+CD8+CD28− T Lymphocytes in Patients with Lupus Nephritis by Marcelina Żabińska, Magdalena Krajewska, Katarzyna Kościelska-Kasprzak, Marian Klinger

“…The results of studies on the CD3+CD8+CD28- cells in SLE are inconsistent since several analyses describe CD3+CD8+CD28- as either immunosuppressive or cytotoxic. The aim of this study is to inquire whether the quantitative changes of CD3+CD8+CD28- T lymphocytes subpopulation are related to the clinical status of patients with lupus nephritis. …”
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Hepatotoxic Effects of Gaseous Sulfur Dioxide (SO₂), Nitrogen Dioxide (NO₂), and Their Mixture on Sea Bass (Centropristis striata): Hematological, Biochemical and Genotoxic Studies... by N. Gandhi, Y. Rama Govinda Reddy and Ch. Vijaya

“…Significant declines in albumin levels, indicating potential liver dysfunction or inflammation due to SO2 and NO2 exposures, were observed at all experimental conditions, while decreased globulin levels suggest immunosuppressive effects from combined pollutants. A substantial increase in the albumin/globulin ratio further signals an imbalance indicative of potential liver dysfunction or inflammation. …”
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A Novel Pyroptosis-Based Prognostic Model Correlated with the Parainflammatory Immune Microenvironment of Pancreatic Cancer by Kong-kong Wei, Zhi-xing Du, Jun-ge Deng, Jin-wei Yang, Hao Chen

“…High-risk patients possessed different molecular pathways, higher KRAS and TP53 mutations, increased expression of PD-L1, C1 immune subtype, and immunosuppressive microenvironment characterized by parainflammation compared to low-risk patients. …”
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