Management of connective tissue disease-associated interstitial lung disease by Keerthi Talari

“…Corticosteroids (except in systemic sclerosis [SSc]-ILD) in combination with immunosuppressants form the mainstay of therapy in CTD-ILD. …”
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Overview of Newer Glucocorticosteroid Preparations for Inflammatory Bowel Disease by R Brattsand

“…This means that there is a high potential for anti-inflammatory and immunosuppressive actions on rectal and bowel mucosa. The compound is metabolically stable in the bowel compartment, which allows full retention of glucocorticosteroid activity in the target organ. …”
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Pas de Deux: Active Ulcerative Colitis in an HIV-Positive Patient by David C Pearson, Lloyd R Sutherland, Stephan Urbanski

“…It also presents a difficult management problem because the patient has a limited life expectancy and is reluctant to accept colectomy, and further immunosuppressive therapy may be dangerous.…”
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Posttranslational Modifications and the Immunogenicity of Biotherapeutics by Roy Jefferis

“…Alternate strategies for inducing immunosuppression or tolerance are discussed.…”
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Protein Phosphatase 2A: Role in T Cells and Diseases by Suyasha Roy, Lalit Batra

“…Genetic deletion of PP2A in Tregs disrupts Foxp3 expression due to hyperactivation of mTORC1 signaling which impairs the development and immunosuppressive functions of Tregs. PP2A is important in the induction of Th9 cells and promotes their antitumor functions. …”
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Seronegative autoimmune hepatitis by A. O. Buyeverov

“…According to available information one can postulate following: 1) clinical vigilance for SAH, especially at liver diseases with high biochemical activity; 2) performing liver biopsies in all cases of unclear diagnosis; 3) application of standard scoring diagnostic system at autoimmune hepatitis; 4) prescription of immunosuppressive therapy at justified suspicion for SAH (at ruling out of the other causes for liver disease). …”
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Sensory-Motor Polyneuropathy and Digital Ischemia: A Rare Presentation of Granulomatosis with Polyangiitis by Wasundara Wathurapatha, B. G. A. Rathnamali, Upul Dissanayake

“…She made a good recovery following aggressive immunosuppressive treatment with methylprednisolone and cyclophosphamide and was maintained on prednisolone and azathioprine. …”
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Listeria monocytogenes Meningoencephalitis and Cerebral Abscess in a Heart Transplant Recipient by Paul C. Adjei

“…Prior to presentation, he had low-level cytomegalovirus (CMV) viremia for two straight weeks. Given his immunosuppression, diarrhea, and low-level CMV viremia, he was presumed to have cytomegalovirus and/or C. difficile colitis and treated empirically for both on hospital day one. …”
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Transient Complete Recovery of Chronic Refractory Idiopathic Thrombocytopenic Purpura after Treatment with Monoclonal Antibody Targeting SARS-CoV-2 Spike Protein by Pooja Gogia, Yiqing Xu

“…Therapy for ITP relies on competing and inhibiting the autoantibody binding and destruction (intravenous immunoglobulin and anti-D immunoglobulin and spleen tyrosine kinase (Syk) inhibitor fostamatinib), augmenting platelet production (thrombopoietin receptor agonists), immunosuppression to reduce the autoantibody production, as well as splenectomy. …”
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Rare diagnosis of an Epstein-Barr virus-positive extracavitary/solid variant of primary effusion lymphoma by duodenal endoscopic biopsy in a human immunodeficiency virus-seronegati... by Beril Guler, Guven Cetin

“…Virus-associated lymphoproliferative disorders should be considered in the differential diagnosis of patients without a history of immunosuppression or HIV infection.…”
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Vasculitic Tibial Mononeuropathy Associated with Inherited Immune Dysregulation: A Review of Tibial Mononeuropathies with Electrodiagnostic Considerations by James Liu, Yue Ding, Sandra Camelo-Piragua, James Richardson

“…She was then started on appropriate immunosuppressive treatment which resulted in significant pain relief and was discharged home. …”
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A Review on the Application of PD-1 Blockade in EBV-Associated Nasopharyngeal Carcinoma Immunotherapy by Jin Bian, Yan Niu, Yanli Ma, Fuhua Chen, Ning Ma

“…Although radiotherapy and chemotherapy are effective treatments for NPC, they have immunosuppressive effects. Immunotherapy has got considerable attention of clinicians for cancer treatment in recent years due to proven success of PD-1/PD-L 1 inhibition in solid tumors trials. …”
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Challenges of Diagnosing Severe Ehrlichiosis in Orthotopic Liver Transplant Recipients by Melissa Parkinson, Spandana Vuyyuru, Jay Patel, Chinelo Animalu

“…We report a case of a 40-year-old male who received an orthotopic liver transplant six months earlier secondary to primary sclerosing cholangitis, on chronic immunosuppressive medication, who presented with complaints of sudden onset fever associated with nausea, vomiting, and diarrhea. …”
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The impact of climate change on the epidemiology of fungal infections: implications for diagnosis, treatment, and public health strategies by Mary E. George, Tonisha T. Gaitor, David B. Cluck, Andrés F. Henao-Martínez, Nicholas R. Sells, Daniel B. Chastain

“…Simultaneously, human factors such as declining immunity, aging populations, and increased use of immunosuppressive therapies are enhancing host susceptibility. …”
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Autologous Cord Blood Therapy for Infantile Cerebral Palsy: From Bench to Bedside by A. Jensen

“…Particularly, since the first published double-blind randomized placebo-controlled trial in a paradigm using allogeneic cord blood and erythropoietin to treat cerebral palsy under immunosuppression showed beneficial therapeutic effects in infantile cerebral palsy, long-held doubts about the efficacy of this new cell therapy are dispelled and a revision of therapeutic views upon an ailment, for which there is no cure at present, is warranted. …”
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Extrapulmonary sarcoidosis presenting as myositis: A rare case by Niraj Bohania, Sumeet Singla, Jagriti Nahata, Pijush Kanti Nandi, Seema Daksh, S Anuradha

“…Patient showed marked improvement in her symptoms with immunosuppressive therapy. This case is a rare manifestation of extrapulmonary sarcoidosis and emphasizes the role of FDG-PET in diagnosing these cases.…”
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Lutein Suppresses the Maturation and Function of Bone Marrow-Derived Dendritic Cells by Seulah Choi, Tae Sung Kim, Hui Xuan Lim

“…These results demonstrated that lutein may exhibit immunosuppressive activity by inhibiting the phenotypic and functional maturation of DCs, and provide new evidence for the value of lutein in the search for novel therapeutic agents in the treatment of inflammatory diseases. …”
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Early Posttransplant Isolated v1 Lesion Does Not Need to Be Treated and Does Not Lead to Increased Fibrosis by Irfan Moinuddin, Bijin Thajudeen, Amy Sussman, Machaiah Madhrira, Erika Bracamonte, Mordecai Popovtzer, Pradeep V. Kadambi

“…However, we chose not to augment immunosuppression. The patient’s kidney allograft function improved over time with close monitoring. …”
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Macrophages, Inflammation, and Tumor Suppressors: ARF, a New Player in the Game by Paqui G. Través, Alfonso Luque, Sonsoles Hortelano

“…In most tumors, TAMs show properties of an alternative polarization phenotype (M2) characterized by the expression of a series of chemokines, cytokines, and proteases that promote immunosuppression, tumor proliferation, and spreading of the cancer cells. …”
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Intra-Abdominal Localisation of a Buschke-Lowenstein Tumour: Case Presentation and Review of the Literature by N. E. Wester, E. M. Hutten, C. Krikke, Robert A. Pol

“…Treatment was impeded by cachexia, an immunosuppressive state after kidney transplantation and difficulties in establishing a reliable diagnose. …”
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