Bardet-Biedl Syndrome with a Kidney Transplant, Esophageal Adenocarcinoma, and Postoperative Complications by Georgi Yankov, Teodora Mihalova, Rosen Petkov, Evgeni Mekov, Stefka Yankova, Danail Petrov

“…Seven months later, a rare complication of the immunosuppressive therapy with Cyclosporin A occurred, which consisted of spontaneous bilateral pleural hemorrhage. …”
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Tuberculous Osteomyelitis of the Scapular Spine Revealing HIV-1 Infection by Khaoula Idsaid, Malika Idalene, Khadija Danaoui, Wiam Ait Driss, Rania Elfargani, Nabila Soraa, Noura Tassi

“…This rare form of tuberculosis with an exceptional site revealed a HIV infection with profound immunosuppression. The patient was initiated on anti-tubercular treatment according to Moroccan recommendations.…”
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Management of Recurrent Rectourethral Fistula by York Mason Posterior Transrectal Transsphincteric Approach by Fahri Yetişir, A. Ebru Şarer, H. Zafer Acar, Omer Parlak, Gokhan Osmanoglu, Gulen Karalova

“…We would like to report the management of recurrent RUF following transurethral resection of prostate and RT for prostate carcinoma in an immunosuppressed, 75-year-old patient by York Mason posterior transrectal transsphincteric approach.…”
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Parkinsonism and Sjögren’s Syndrome: A Fortuitous Association or a Shared Immunopathogenesis? by Mariem Kchaou, Nadia Ben Ali, Intissar Hmida, Saloua Fray, Hela Jamoussi, Mohamed Jalleli, Slim Echebbi, Afef Achouri, Samir Belal

“…The diagnosis of primary SS was established and the adjunction of corticotherapy has remarkably improved Parkinson’s signs without use of other immunosuppressive agents. Conclusion. Based on these findings, we discuss the hypothesis of either a causal link between SS and Parkinsonism or a fortuitous association of two distinct pathologies with or without a shared immunopathogenesis.…”
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Micro Immune Response On-chip (MIRO) models the tumour-stroma interface for immunotherapy testing by Alice Perucca, Andrea Gómez Llonín, Oriol Mañé Benach, Clement Hallopeau, Elisa I. Rivas, Jenniffer Linares, Marta Garrido, Anna Sallent-Aragay, Tom Golde, Julien Colombelli, Eleni Dalaka, Judith Linacero, Marina Cazorla, Teresa Galan, Jordi Pastor Viel, Xavier Badenas, Alba Recort-Bascuas, Laura Comerma, Patricia Fernandez-Nogueira, Ana Rovira, Pere Roca-Cusachs, Joan Albanell, Xavier Trepat, Alexandre Calon, Anna Labernadie

“…We demonstrate that IL2-driven immunomodulation increases immune cell velocity and spreading to overcome stromal immunosuppression and restores anti-cancer response in refractory tumours. …”
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Anti-inflammatory actions of acupuncture by Freek J. Zijlstra, Ineke van den Berg-de Lange, Frank J. P. M. Huygen, Jan Klein

“…Mechanisms underlying the ascribed immunosuppressive actions of acupuncture are reviewed in this communication. …”
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High Grade Glioma Mimicking Voltage Gated Potassium Channel Complex Associated Antibody Limbic Encephalitis by Dilan Athauda, R. S. Delamont, E. De Pablo-Fernandez

“…Clinicoradiological progression despite effective immunosuppressive treatment should prompt clinicians to look for alternative diagnoses. …”
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A Rare Cause of Hemophagocytic Lymphohistiocytosis: Fusobacterium Infection—A Case Report and Review of the Literature by Ghulam Rehman Mohyuddin, Heather J. Male

“…Our case highlights Fusobacterium as a rare precipitant of HLH and proves that a high index of clinical suspicion is crucial for early diagnosis of HLH, allowing for prompt initiation of HLH-specific immunosuppressive therapy that can be life-saving.…”
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Adult Dermatomyositis with Bleeding Ulcer in the Pharynx by Junko Kusano, Yuka Takahashi, Yoshikata Misaki, Norihiko Murai

“…Despite medical treatment with corticosteroids and immunosuppressive agents, her DM progressed rapidly, leading to exacerbation of the dysphagia. …”
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Giant Condyloma Acuminatum of Vulva in an HIV-Infected Woman by Athanase Lilungulu, Bonaventura C. T. Mpondo, Abdallah Mlwati, Dismas Matovelo, Albert Kihunrwa, Balthazar Gumodoka

“…The most common risk factor is immunosuppression with HIV; however, any other cause of immunodeficiency can be a predisposing factor. …”
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The Role of Beta HPV Types and HPV-Associated Inflammatory Processes in Cutaneous Squamous Cell Carcinoma by Mircea Tampa, Cristina Iulia Mitran, Madalina Irina Mitran, Ilinca Nicolae, Adrian Dumitru, Clara Matei, Loredana Manolescu, Gabriela Loredana Popa, Constantin Caruntu, Simona Roxana Georgescu

“…Dysregulation of the immune system (chronic inflammation and immunosuppression), environmental factors (ultraviolet radiation), and genetic factors are the most important cofactors involved in beta HPV-related carcinogenesis. …”
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Eales’ Disease: When the Rare Sounds Frequent by Beatriz Oliveira Lopes, Margarida Sena Brízido, Ana Isabel Reis, Margarida Maria Miranda, Susana Morais Pina

“…Therapeutic approach included antituberculosis therapy and systemic steroids, associated or not to immunosuppressive therapy, and retinal scatter photocoagulation in all cases. …”
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Mechanism and Treatment Strategy of Osteoporosis after Transplantation by Lei Song, Xu-Biao Xie, Long-Kai Peng, Shao-Jie Yu, Ya-Ting Peng

“…Bone loss after organ transplant is related to adverse effects of immunosuppressants on bone remodeling and bone quality. …”
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Use of Hyaluronic Acid as Adjuvant in Periodontal Therapy and Healing: a Bibliographic Review by Marcelo Fernando Armijos Briones, Cinthya Lisbeth Sinchiguano Moreano, Coralia de los Ángeles Ortega Medina

“…Hyaluronic acid is a natural non-sulfated polysaccharide of the glycosaminoglycan family, it can cause different responses in the body, the high molecular weight has anti-inflammatory, immunosuppressive and healing effects, while the low molecular weight has proinflammatory properties. …”
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Leprosy with Atypical Skin Lesions Masquerading as Relapsing Polychondritis by Punit Pruthi, Hariharan Munganda, Amit Bangia, Uma Rani, Rajesh Budhiraja, Swapnil Brajpuriya

“…Tissue diagnosis should always be attempted whenever possible in patients presenting with autoimmune features, so that inappropriate therapy with immunosuppressants is avoided.…”
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XMRV Discovery and Prostate Cancer-Related Research by David E. Kang, Michael C. Lee, Jaydip Das Gupta, Eric A. Klein, Robert H. Silverman

“…Subsequent investigations in North America, Europe, Asia, and Africa have either observed or failed to detect XMRV in patients (prostate cancer, chronic fatigue syndrome-myalgic encephalomyelitis (CFS-ME), and immunosuppressed with respiratory tract infections) or normal, healthy, control individuals. …”
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A Case of an Acquired Factor VIII Inhibitor Complicated by Multiple Treatment-Related Opportunistic Infections and Review of the Literature by Anna L. Hutchinson, Yi Ling Tan, Giselle Kidson-Gerber

“…It also raises the issue of routine prophylaxis for immunosuppression in nonmalignant conditions, which will become a common dilemma with the expanding indications for rituximab use.…”
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Predictive role of SLC1A5 in neuroblastoma prognosis and immunotherapy by Jian Cheng, Miaomiao Sun, Xiao Dong, Yang Yang, Xiaohan Qin, Xing Zhou, Yongcheng Fu, Yuanyuan Wang, Jingyue Wang, Da Zhang

“…Immune infiltration analysis revealed a more immunosuppressive tumor microenvironment associated with high SLC1A5 expression. …”
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Corticosteroid use beyond 1-year post heart transplantation is associated with worse outcomes: A contemporary analysis of the ISHLT registry by Abhishek Jaiswal, MD, William L. Baker, Pharm.D, Ashwin Pillai, MD, Michelle Kittleson, MD, PhD, Balaphanidhar Mogga, MD, Zeina Jedeon, MD, Caroline Chen, David A. Baran, MD

“…Introduction: Immunosuppressive drugs ensure graft survival in heart transplantation (HT). …”
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Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum for the rheumatologist by Jyoti Ranjan Parida, Saumya Ranjan Tripathy

“…Supportive care is the mainstay of treatment and if not started promptly may result in high mortality and morbidity. Although many immunosuppressive drugs have been tried in treatment, no treatment has proven beneficial except cyclosporine which has been shown to retard the progression of SJS/TEN. …”
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