Pulmonary Arterial Hypertension in Adult-Onset Still’s Disease: Rapid Response to Anakinra by Marc Campos, Elena Schiopu

“…After unsuccessful exposure to various immunosuppressive regimens, shortly following the initiation of anakinra, an interleukin-1 (IL-1) receptor antagonist, her disease became quiescent and the PAH resolved. …”
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Mortality Associated with Recurrent Extreme Hyperferritinemia in Critically Ill Adolescents by John Scott Baird

“…Recurrent extreme hyperferritinemia may be a novel biomarker of increased mortality in patients with the syndrome of persistent inflammation, immunosuppression, and catabolism.…”
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Funding for research on cryptococcal disease: an analysis based on the G-finder report by Iraine Duarte, Marcio L. Rodrigues

“…Abstract Members of the genus Cryptococcus are the causative agents of cryptococcal meningitis, a disease mainly associated with HIV-induced immunosuppression. Patients with cryptococcal meningitis are at a serious risk of death. …”
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Significance of Urinary Proteome Pattern in Renal Allograft Recipients by Sufi M. Suhail

“…Substantial numbers of studies have shown that different renal allograft disease states, both acute and chronic, could portray unique urinary proteome pattern enabling early diagnosis of graft dysfunction and proper manipulation of immunosuppressive strategy that could impact graft prognosis. …”
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Insulin Autoimmune Syndrome: A Systematic Review by MingXu Lin, YuHua Chen, Jie Ning

“…For patients with severe symptoms, available treatments may include drugs that reduce pancreatic insulin secretion (such as somatostatin and diazoxide), immunosuppressants (glucocorticoids, zaprin, and rituximab), and even plasma exchange to remove autoantibodies from the body. …”
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Toll-Like Receptor 4 Activation in Cancer Progression and Therapy by Alja Oblak, Roman Jerala

“…While TLR4 activation can promote antitumor immunity, it can also result in increased tumor growth and immunosuppression. Nevertheless, TLR4 engagement by endotoxin as well as by endogenous ligands represents notable contribution to the outcome of different cancer treatments, such as radiation or chemotherapy. …”
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Extensive Longitudinal Transverse Myelitis after Influenza A Virus Infection in a Patient with Systemic Lupus Erythematosus by Suheiry Márquez, Luis M. Vilá

“…This case highlights the importance of early recognition and prompt treatment with immunosuppressive drugs in such cases.…”
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Desquamative interstitial pneumonia: If there is smoke there is fire by Amit Panjwani, Husain Kadhem, Saadeya Naji Abdulkarim, Umesh Nabar

“…We present a rare case of DIP in a nonsmoker, who was initially labeled as idiopathic ILD but eventually evolved into IPAF and exhibited a good response to immunosuppressive treatment.…”
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A Case of Superficial Mycoses in a Patient with Systemic Lupus Erythematosus by Li Z, Lu J, Yang Z

“…The fungal infection was further aggravated by the patient’s 10-year history of SLE and long-term immunosuppressive drug therapy. Ultimately, Fungal microscopy and culture results were consistent with superficial mycosis. …”
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Characteristics, pathogenic and therapeutic role of gut microbiota in immunoglobulin A nephropathy by Kaijin Yao, Lingqian Zheng, Wenmin Chen, Yina Xie, Chunling Liao, Tianbiao Zhou

“…Current treatments for IgAN include supportive care and immunosuppressive therapy. A growing number of studies found that the gut microbiota in IgAN was dysregulated. …”
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Varicella-Zoster Meningitis in an Immunocompetent Male without Fever or Rash by Raju Raghunathan, Qasim Khalil, Mohamad Mooty

“…Following the primary infection, VZV can remain latent and can reactivate decades later to produce Zoster, being more common in the elderly as well as immunosuppressed individuals. The diagnosis of both the primary and reactivation is mostly clinical from the typical rash. …”
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The Occurrence of Aflatoxins in Date Palm (Phoenix dactylifera L.) Worldwide by Merfat Abdulrahman Almaghrabi

“…Aflatoxins pose serious health hazards to humans’ and animals’ health because of their carcinogenic, mutagenic, and teratogenic properties and their immunosuppressive effects. Aflatoxin contamination in various agricultural commodities has attracted much attention worldwide. …”
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A new paradigm for cancer immunotherapy: targeting immunogenic cell death-related noncoding RNA by Guojuan Sun, Ling He

“…Immunogenic cell death (ICD) can amplify the antitumor immune responses and reverse the immunosuppressive tumor microenvironment, thus increasing the sensitivity of cancer immunotherapy. …”
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Treatment of neuro-invasive listeriosis: an overview by P. Gudeikaitė, J. Valaikienė, R. Mameniškienė

“…The most at-risk populations are pregnant women, neonates, people over 65 years of age, and patients with chronic diseases or using immunosuppressive drugs. In case of suspected acute meningitis, encephalitis or meningoencephalitis in these individuals, it must be considered that the pathogen can be Listeria monocytogenes, which is resistant to the therapy of cephalosporins. …”
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Resolved Hepatitis B: Achieved or Imaginary Wellbeing? by S. N. Batskikh

“…Occult HBV infection in PHB individuals can reactivate at background immunosuppressive or chemotherapies. PHB with chronic liver diseases of various aetiology significantly rises the risk of cirrhosis and hepatic cancer. …”
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Multiple cranial neuropathies in Churg-Strauss syndrome: case report by G. Rutkauskaitė, R. Masaitienė, J. Dadonienė, D. Jatužis

“…Patients are treated with glucocorticoids and immunosuppressants. We describe a case report of a 68-year-old woman with a clinical diagnosis of Churg-Strauss syndrome and multiple cranial neuropathies. …”
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Surgical Site Infections Complicating the Use of Negative Pressure Wound Therapy in Renal Transplant Recipients by Susanna Lam, Ngee-Soon Lau, Jerome Martin Laurence, Deborah Jean Verran

“…Our case series demonstrates that in immunosuppressed transplant recipients, there may be ineffective microbial or bacterial bioburden clearance associated with the NPWT, which can lead to further infections. …”
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Vascular Endothelial Cell Function in Catastrophic Antiphospholipid Syndrome: A Case Report and Review of the Literature by B. Routy, T. Huynh, R. Fraser, C. Séguin

“…Despite survival improvement with new generation immunosuppressive agents, their mechanisms of action are poorly defined, and CAPS is still considered a high-risk complication in patients known with antiphospholipid antibody syndrome. …”
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Cutaneous Squamous Cell Carcinoma of the Head and Neck by Vivek V. Gurudutt, Eric M. Genden

“…Large tumors, deep tissue invasion, perineural involvement, recurrence, location in high-risk areas, and immunosuppression are implicated in worsening prognosis. …”
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Respiratory Syncytial Virus Pneumonia Treated with Lower-Dose Palivizumab in a Heart Transplant Recipient by J. L. Grodin, K. S. Wu, E. E. Kitchell, J. Le, J. D. Mishkin, M. H. Drazner, D. W. Markham

“…Respiratory syncytial virus (RSV) is an important community-acquired pathogen that can cause significant morbidity and mortality in patients who have compromised pulmonary function, are elderly, or are immunosuppressed. This paper describes a 70-year-old man with a remote history of heart transplantation who presented with signs and symptoms of pneumonia. …”
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