Management of Idiopathic Granulomatous Mastitis: Effectiveness of a Steroid-Free Regimen Using Tinospora cordifolia—A Single-Institution Experience by Ankita Das Sheth, Shalaka Joshi, Arul Kumar, Nita Nair, Tanuja Shet, Ayushi Sahay, Palak Thakkar, Purvi Haria, Aparna Katdare, Vani Parmar, Sangeeta Desai, Rajendra Badwe

“…We report the efficacy of steroid-free management of IGM with immunomodulatory herbal origin phytopharmaceutical drug Tinosporin. …”
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Sporadic inclusion body myositis in the rheumatology clinic by Fernando Henrique Carlos de Souza, Gustavo Luiz Behrens Pinto, Jean Marcos de Souza, Pablo Arturo Olivo Pallo, Leonardo Santos Hoff, Samuel Katsuyuki Shinjo

“…., glucocorticoid, and immunosuppressive/immunomodulatory/immunobiological drugs). Although there have been no robust clinical trials, training exercise/physiotherapy should be prescribed regularly in sIBM patients.…”
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Macrolide Use in the Treatment of Critically Ill Patients with Pneumonia: Incidence, Correlates, Timing and Outcomes by Wendy I Sligl, Holly Hoang, Dean T Eurich, Atul Malhotra, Thomas J Marrie, Sumit R Majumdar

“…Evidence suggests that macrolides may also decrease mortality in severe sepsis via immunomodulatory properties.…”
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Effects of Anti-Cytokine Antibodies on Gut Barrier Function by Fang Liu, Seul A. Lee, Stephen M. Riordan, Li Zhang, Lixin Zhu

“…Patients with these diseases often have a compromised gut barrier function, suggesting that anti-cytokine antibodies may contribute to the re-establishment of gut barrier integrity, in addition to their immunomodulatory effects. This paper reviews the effects of anti-cytokine antibodies on gut barrier function and their mechanisms.…”
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Immunomodulation in the Treatment of Refractory Catastrophic Antiphospholipid Syndrome by Karthik Nath, Andrew McCann

“…Despite this, the patient continued to demonstrate clinical features concerning for ongoing small vessel occlusion necessitating aggressive immunomodulatory therapy in the form of intravenous immunoglobulin, plasma exchange, and rituximab.…”
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Treatment of HIV-1 Infection with Combination Therapy: Antiretroviral Agents and Biological Response Modifiers by Steven M Schnittman

“…Preliminary evaluations of the combination of zidovudine wilh interferon alpha (IFN-α) have demonstrated enhanced antiviral. antitumour and immunomodulatory activity. Other promising approaches include antiretroviral therapy with interleukin (IL) -2, and IFN-α wilh IL-2. …”
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Application of natural β-glucans as biocompatible functional nanomaterials by Xiaojie Li, Peter Chi Keung Cheung

“…Naturally-occurring β-glucans are mostly investigated for their antitumor activity and immunomodulatory property. They have been widely regarded as a natural source for functional foods and pharmaceuticals. …”
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Emerging Implications for Extracellular Matrix-Based Technologies in Vascularized Composite Allotransplantation by Ricardo Londono, Vijay S. Gorantla, Stephen F. Badylak

“…When properly configured, customized, and implemented, biomaterials derived from the extracellular matrix (ECM) retain bioactive molecules and immunomodulatory properties that can promote stem cell migration, proliferation and differentiation, and constructive functional tissue remodeling. …”
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Paroxysmal Amnesia Attacks due to Hashimoto’s Encephalopathy by Pelin Nar Senol, Aylin Bican Demir, Ibrahim Bora, Mustafa Bakar

“…Although symptoms suggest a nonlesional encephalopathy in most of the cases, sometimes the clinical appearance can be subtle and may not respond to immunosuppressants or immunomodulatory agents. Here we report a case who presented with drowsiness and amnestic complaints associated with paroxysmal electroencephalography (EEG) abnormalities which could be treated only with an antiepileptic drug.…”
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Human Primary Monocytes as a Model for in vitro Immunotoxicity Testing: Evaluation of the Regulatory Properties of TiO2 Nanoparticles by Svadlakova T, Kolackova M, Kulich P, Kotoucek J, Rosecka M, Krejsek J, Fiala Z, Andrýs C

“…Nanoparticles alone did not induce substantial production of inflammatory cytokines IL-1β, IL-6, or TNF-α. The immunomodulatory effect on NLRP3 depended on the type of costimulant used. …”
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Advance of Mesenchymal Stem Cells in Chronic End-Stage Liver Disease Control by Yun Gao, Xiushan Yin, Xiaomeng Ren

“…MSCs can secrete a large number of cytokines, chemokines, immunomodulatory molecules, and hepatotrophic factors, as well as produce extracellular vesicles. …”
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The Fruit Malus prunifolia (Malus micromalus Mak.): A Minireview of Current Knowledge of Fruit Composition and Health Benefits by Xiaolong Ji, Chunyan Hou, Xudan Guo

“…Recent phytochemical studies on the fruit have shed some light on its biological activities, such as anticancer, immunomodulatory, antioxidant, immunostimulating, hepatoprotective, and gastrointestinal protective activities. …”
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Modulation of Immunoregulatory Properties of Mesenchymal Stromal Cells by Toll-Like Receptors: Potential Applications on GVHD by Bruno Sangiorgi, Rodrigo Alexandre Panepucci

“…In the last decade, the immunomodulatory properties of mesenchymal stromal cells (MSCs) have attracted a lot of attention, due to their potential applicability in the treatment of graft-versus-host disease (GVHD), a condition frequently associated with opportunistic infections. …”
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Interface Molecules of Angiostrongylus cantonensis: Their Role in Parasite Survival and Modulation of Host Defenses by Alessandra L. Morassutti, Carlos Graeff-Teixeira

“…As a mechanism of neutralizing these host defenses, A. cantonensis expresses different molecules with immunomodulatory properties that are excreted or secreted (ES). …”
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Studies on the Interleukin-10 Gene in Animal Models of Colitis by Hugh J Freeman

“…Interleukin-10 (IL-10) has both immunomodulatory and anti-inflammatory properties. IL-10-deficient mice develop intestinal inflammation with increased tissue levels of other cytokines, including tumour necrosis factor-alpha. …”
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Umbilical Cord as Prospective Source for Mesenchymal Stem Cell-Based Therapy by Irina Arutyunyan, Andrey Elchaninov, Andrey Makarov, Timur Fatkhudinov

“…The paper presents current evidence on the properties of human umbilical cord-derived mesenchymal stem cells, including origin, proliferative potential, plasticity, stability of karyotype and phenotype, transcriptome, secretome, and immunomodulatory activity. A review of preclinical studies and clinical trials using this cell type is performed. …”
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The Effect of Edible Mushroom on Health and Their Biochemistry by Anmut Assemie, Galana Abaya

“…These compounds have a wide range of therapeutic effects and can act as immunomodulatory, anticarcinogenic, antiviral, antioxidant, and anti-inflammatory agents. …”
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Umbilical Cord Mesenchymal Stromal Cells for Cartilage Regeneration Applications by E. Russo, M. Caprnda, P. Kruzliak, P. G. Conaldi, C. V. Borlongan, G. La Rocca

“…Umbilical cord- (UC-) MSCs gained increasing interest due to their multilineage differentiation potential, immunomodulatory, and anti-inflammatory properties as well as higher proliferation rates, abundant supply along with no risks for the donor compared to adult MSCs. …”
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Drugs as a cause of perforating dermatoses – a literature review by Lidia Mądrzak, Izabela Staniszewska, Arkadiusz Moskwa, Agnieszka Kalińska-Bienias

“…Perforating dermatoses can be induced by the molecularly targeted therapy drugs (sorafenib, nilotinib, dasatinib, erlotinib, gefitinib, vemurafenib, lenvatinib, sirolimus, bevacizumab, necitumumab, panitumumab, cetuximab, bendamustine-rituximab, terepril), monoclonal antibodies (infliximab, etanercept, ranibizumab, natalizumab), as well as immunomodulatory imide drugs (lenalidomide, leflunomide), antiretroviral drugs (indinavir, telaprevir) and penicillamine. …”
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Role of Carbamazepine in the Symptomatic Treatment of Subacute Sclerosing Panencephalitis: A Case Report and Review of the Literature by Sandhya Ravikumar, John Ross Crawford

“…After extensive workup, a diagnosis of subacute sclerosing panencephalitis was suspected by the presence of period epileptiform discharges on electroencephalogram and confirmed by elevated measles titers in the cerebrospinal fluid. Combination immunomodulatory therapy with isoprinosine, ribavirin, and intra-Ommaya interferon alpha did not result in clinical improvement. …”
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