Case Report: Rare cardiovascular characteristics of tuberous sclerosis complex with novel TSC2 variant by Zhiqin Du, Xiao Ma, Xiao Ma, Xiao Ma, Jianhua Li, Fang Yang, Yangfan Guo, Yangfan Guo

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Possible Implication of Local Immune Response in Darier's Disease: An Immunohistochemical Characterization of Lesional Inflammatory Infiltrate by Clelia Miracco, Francesco Pietronudo, Vasileios Mourmouras, Michele Pellegrino, Monica Onorati, Maria Grazia Mastrogiulio, Luca Cantarini, Pietro Luzi

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Atypical Femoral Fracture in Hypophosphatasia: A Systematic Review by Nipith Charoenngam, Jerapas Thongpiya, Pitchaporn Yingchoncharoen, Ben Ponvilawan, Mehmet S. Marangoz, Jirat Chenbhanich, Patompong Ungprasert

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The Utility of Synovial Fluid Interleukin-10 in Diagnosing Chronic Periprosthetic Joint Infection: A Prospective Cohort Study by Zou Y, Yang Y, Yang J, Zhang Y, Zhao C, Qin L, Hu N

“…Yinshuang Zou,1– 3,* Yaji Yang,1,3,* Jianye Yang,1,3 Yanhao Zhang,4 Chen Zhao,1,3 Leilei Qin,1,3 Ning Hu1,3 1Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Department of Orthopedics, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, 434000, People’s Republic of China; 3Laboratory of Orthopedics, Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 4National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Army Medical University, Chongqing, 400038, People’s Republic of China*These authors contributed equally to this workCorrespondence: Leilei Qin; Ning Hu, Email qinleilei@stu.cqmu.edu.cn; huning@cqmu.edu.cnBackground: Diagnosing chronic periprosthetic joint infection (PJI) is challenging. …”
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In-Situ Electrospinning Dressings Loaded with Kaempferol for Reducing MMP9 to Promote Diabetic Ulcer Healing by Li J, Meng H, Guo W, Zhou L, Wu S, Gao G, Liu Q, You D, Qu W

“…The high porosity of biomaterials induces more M2 macrophages, while the natural compound kaempferol inhibits the expression of matrix metalloproteinase 9 (MMP9) and thus inhibits the associated inflammatory and immunological responses.Methods: portable electrospinning dressings (PEDs) were prepared from the spinning solution using a portable electrospinning device. …”
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The Association Between the CALLY Index and All-Cause Mortality in Patients with COPD: Results from the Cohort Study of NHANES 2007–2010 by Ding Y, Liu Y, Yu J, Cai C, Fu L, Zhu J, Yang S, Jiang Y, Wang J

“…This index provides a thorough assessment of a patient’s inflammation level, nutritional condition, and immunological function. The objective of this study is to examine the correlation between the CALLY index and all-cause mortality in COPD patients.Methods: We calculated the CALLY index using data from the National Health and Nutrition Examination Survey (NHANES) for the 2007– 2008 and 2009– 2010 cycles, extracted from the participants’ peripheral blood samples. …”
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Anatomy, histology, and morphology of fish gills in relation to feeding habits: a comparative review of marine and freshwater species by Mohamed A. M. Alsafy, Hanan H. Abd-Elhafeez, Ahmed M. Rashwan, Atef Erasha, Safwat Ali, Samir A. A. El-Gendy

“…The lymph space contains many types of immunological cells, including lymphocytes, granular leukocytes, and rodlet cells. …”
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Transcriptomic profiles of monocyte-derived macrophages exposed to SARS-CoV-2 VOCs reveal immune-evasion escape driven by delta by Alessia Gallo, Josè Camilla Sammartino, Roberta Vazzana, Roberto Giambruno, Claudia Carcione, Nicola Cuscino, Salvatore Castelbuono, Vitale Miceli, Matteo Bulati, Daniele Lilleri, Irene Cassaniti, Pier Giulio Conaldi, Fausto Baldanti

“…In particular, our RNA-Seq analysis showed a significant up-regulation of several genes involved in different immunological processes, such as PARP9/PARP14 axes, in macrophages exposed to D614G, Alpha, and Gamma variants. …”
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Effectiveness of Contrast Agents and Molecular Indicators in Alzheimer's Diagnosis Through PET and SPECT Imaging on Animal Models by Yasaman Abaszadeh, Ramin Ardalani, Athena Dehghan Najm Abadi

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A Case Study Identified a New Mutation in the TTN Gene for Inherited Hypertrophic Cardiomyopathy by Dong J, Liu M, Chen Q, Zha L

“…Jiangtao Dong,1– 4,* Meilin Liu,1– 3,* Qianwen Chen,1– 3,5 Lingfeng Zha1– 3 1Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 2Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 3Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 4Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 5Department of Pediatric Cardiology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430070, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lingfeng Zha, Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, People’s Republic of China, Tel +86-15827177185, Email zhalf@hust.edu.cnBackground: Hypertrophic cardiomyopathy (HCM) is the most common hereditary cardiomyopathy, with variable pathogenesis, clinical presentation, and prognosis. …”
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Abnormal Expression of Peripheral Blood Leukocyte Surface Markers in Retinopathy of Prematurity Patients by Guo R, Cheng F, Meng XJ, Fan JM, Lu YL, Ma XH, Qiao X, Li JH

“…Rui Guo,1 Fang Cheng,1 Xiang-Jie Meng,2,3 Jun-Mei Fan,4 Ya-Ling Lu,5 Xiao-Hui Ma,6 Xin Qiao,6 Jun-Hong Li7 1Department of Ophthalmology, Children’s Hospital of Shanxi and Women Health Center of Shanxi, Affiliated to Shanxi Medical University, Taiyuan, 030000, People’s Republic of China; 2Department of Pediatric Stomatology, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, People’s Republic of China; 3Department of Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, People’s Republic of China; 4Department of Reproductive Medicine Center, Children’s Hospital of Shanxi and Women Health Center of Shanxi, Affiliated to Shanxi Medical University, Taiyuan, 030000, People’s Republic of China; 5School of Basic Medicine, Shanxi Medical University, Taiyuan, 030001, People’s Republic of China; 6Department of Shanxi Province Key Laboratory of Ophthalmology, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, 030002, People’s Republic of China; 7Department of Strabismus and Pediatric Ophthalmology, Shanxi Eye Hospital, Affiliated to Shanxi Medical University, Taiyuan, 030002, People’s Republic of ChinaCorrespondence: Jun-Hong Li, Department of Strabismus and Pediatric Ophthalmology, Shanxi Eye Hospital Affiliated to Shanxi Medical University, No. 100 Fudong Street, Taiyuan, 030002, People’s Republic of China, Tel +8613834131099, Email junhongliljh@126.comObjective: Our study compares immune cell profiles in preterm infants with and without severe ROP, identifying risk factors for its development to explore both immunological aspects and determinants of ROP in preterm infants.Methods: Infants born between January 2023 to December 2023 at the Children’s Hospital of Shanxi were enrolled in this study according to the inclusion criteria. …”
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Potential of Eurycoma longifolia, Curcuma zedoaria, and Allium sativum extracts as phytobiotics for shrimp health by Mohamad Iqbal Kurniawinata, Sukenda Sukenda, Dinamella Wahjuningrum, Widanarni Widanarni, Julie Ekasari

“…The results from the second stage demonstrated that dietary phytobiotic extract addition enhances the immunological responses and improves the shrimp survival against V. parahaemolyticus challenge compared to the control group. …”
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Comprehensive Analysis of Programmed Cell Death-Related Genes in Diagnosis and Synovitis During Osteoarthritis Development: Based on Bulk and Single-Cell RNA Sequencing Data by Zhou J, Jiao S, Huang J, Dai T, Xu Y, Xia D, Feng Z, Chen J, Li Z, Hu L, Meng Q

“…We identified two distinct PCD clusters, each exhibiting unique molecular and immunological characteristics. Single-cell RNA sequencing further revealed dynamic and complex cellular changes in OA synovial tissue, with differential expression of Hub PCD-DEGs across various immune cell types.Conclusion: Our study suggests that PCD-related genes may be involved in development of OA synovitis. …”
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Development and optimization of a new competitive ELISA using recombinant (rPSA D15 and rCag11) antigens for the detection of Helicobacter pylori infection. by Biniam Moges Eskeziyaw, Naomi Maina, Rebecca Waihenya, Matthew Mutinda Munyao, Tonny Teya Nyandwaro, Shingo Inoue, Samson Muuo Nzou

“…To address the challenge of H. pylori infection, numerous immunological assays have been developed for its diagnosis and management. …”
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Extensive Inactive Neurocysticercosis: A Case Report in Mbeya, Southern Highlands of Tanzania by Makasi CE, Ngowi BJ, Stelzle D, Kilale AM, Mahande MJ, Welte TM, Winkler AS, Mmbaga BT

“…It is influenced by the number, size, location, and stage of the cysts, as well as the parasite’s potential to cause inflammation and the immunological response of the host. So far, little is known about how Human Immunodeficiency Virus (HIV) co-infection modifies clinical NCC presentation. …”
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Enhancing doctor-patient communication using large language models for pathology report interpretation by Xiongwen Yang, Yi Xiao, Di Liu, Yun Zhang, Huiyin Deng, Jian Huang, Huiyou Shi, Dan Liu, Maoli Liang, Xing Jin, Yongpan Sun, Jing Yao, XiaoJiang Zhou, Wankai Guo, Yang He, WeiJuan Tang, Chuan Xu

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Clinical Characteristics, Laboratory Parameters, and Molecular Epidemiology of Neuroinvasive Flavivirus Infections in a Hotspot Region of Eastern Croatia by Dario Sabadi, Kristian Bodulić, Vladimir Savić, Nika Vlahović Vlašić, Maja Bogdanić, Ljiljana Perić, Irena Tabain, Dubravka Lišnjić, Mario Duvnjak, Snježana Židovec-Lepej, Barbara Grubišić, Ilija Rubil, Ljubo Barbić, Luka Švitek, Vladimir Stevanović, Petra Smajić, Bernarda Berišić, Mihaela Zlosa, Ivana Rončević, Tatjana Vilibić-Čavlek

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Connecting The Dots: The Impact Of Subclinical Hypothyroidism On Female Subfertility And Obesity by Naila Ashfaq, Warda Hussain, Mugheera Hussain, Neelam Saba, Asma Muddasir, Jawairiah Liaqat

“… • Bendary AA, El Hodiby ME. Study of thyroid immunological and functional disorders in women with unexplained infertility 2022; 2(63): 1-6 • Wali AA-E-D, Abdelfattah W, Abd-El-Fatah SM. …”
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