Immune Cell Profiling Reveals a Common Pattern in Premetastatic Niche Formation Across Various Cancer Types by Shigeaki Sugiyama, Kanae Yumimoto, Keiichi I. Nakayama

“…Machine learning using immune cell profiles could predict the metastatic phase with approximately 75% accuracy. …”
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Hypoxia and lipid metabolism related genes drive proliferation migration and immune infiltration mechanisms in colorectal cancer subtyping by Shansong Huang, Huiying Wang, Jiaqing Cao, Qiang Pang

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Remodelling of the immune landscape by IFNγ counteracts IFNγ-dependent tumour escape in mouse tumour models by Vivian W. C. Lau, Gracie J. Mead, Zofia Varyova, Julie M. Mazet, Anagha Krishnan, Edward W. Roberts, Gennaro Prota, Uzi Gileadi, Kim S. Midwood, Vincenzo Cerundolo, Audrey Gérard

“…This altered myeloid compartment synergises with an increase in antigen-specific CD8+ T cells to promote anti-tumour immunity against IFNγ receptor-deficient tumours, with such an immune crosstalk observed around blood vessels. …”
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Identification of a Novel Prognostic Lymphangiogenesis-Related Signature Associated with Tumor Immunity for Guiding Therapy in Lung Adenocarcinoma by Juan Peng, Dan Liu, Hong-feng Zhang, Qi-hao Hu, Wen Chen, Juan Zou, Juan Zhang, Hui Li, An-bo Gao, Yu-kun Li

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PNMA1 is a novel immune modulator and therapeutic target in hepatocellular carcinoma linked to bile acid metabolism by Hongyu Chu, Yuezhan Shan, Chengwei Jiang, Yumin Zhong, Zijing Liu, Xuedong Fang, Zhaoying Yang

“…The relevance of PNMA1 extends to immune factors such as M1 macrophages, CD8+ T cells, and immune checkpoints. …”
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Platelet mass index, systemic immune-inflammation index, and neutrophil-lymphocyte ratio as practical markers in childhood brucellosis by Hilal Koyuncu, Ayşe Tolunay Oflu, Ayşe Güngör, Ayşegül Bükülmez

“…This study aimed to examine the platelet mass index (PMI), the neutrophil-lymphocyte ratio (NLR), and systemic immune-inflammation index (SII) in children with brucellosis and to determine their roles in focal involvement. …”
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Immune status improvement in piglets through the use of interferon-containing products during specific prevention of porcine pleuropneumonia by A. G. Shakhov, L. Yu. Sashnina, V. A. Prokulevich, Yu. Yu. Vladimirova, M. I. Adodina

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Glucocorticoid-Induced TNFR-Related (GITR) Protein and Its Ligand in Antitumor Immunity: Functional Role and Therapeutic Modulation by Theresa Placke, Hans-Georg Kopp, Helmut Rainer Salih

“…The ability of the tumor necrosis factor receptor (TNFR) family member GITR to modulate immune responses has been the subject of multiple studies. …”
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Treatment of Severe Odynophagia with Long-Acting Topical Nitroglycerin Ointment in a Patient with Acquired Immune Deficiency Syndrome by Young-In Kim, Fred Saibil, Anita Rachlis

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Nivolumab (Opdivo) in PD-1 pathway inhibition: Enhancing immune response in recurrent oral squamous cell carcinoma by J. Nandhini, E. Karthikeyan

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Short-term effects of follicle-stimulating hormone on immune function, lipid, and vitamin metabolism in transiently castrated men by Jéssica Guedes, Indira Pla, Aniel Sanchez, Gyorgy Marko-Varga, Gilberto Barbosa Domont, K Barbara Sahlin, Berk Hazir, Aleksander Giwercman, Fábio César Sousa Nogueira, Johan Malm, Yvonne Lundberg Giwercman

“…Results: FSH significantly upregulates key proteins involved in the modulation of inflammatory response and innate immune system (P ≤ 0.03) and dysregulates lipid metabolism, evidenced by downregulation of multiple apolipoproteins (P ≤ 0.04) and increased levels of cholesterol and glycerophospholipids (P ≤ 0.03). …”
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Exploring potential biomarkers for acute myocardial infarction by combining circadian rhythm gene expression and immune cell infiltration by Xiao Yu, Xiaopeng Zhang, Hazrat Bilal, Chang Shi, Lei Sun

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The Role of β-Catenin in Th1 Immune Response against Tuberculosis and Profiles of Expression in Patients with Pulmonary Tuberculosis by Kunlong Xiong, Jinxia Niu, Ruijuan Zheng, Zhonghua Liu, Yanzheng Song, Lin Wang, Changtai Zhu, Lin Fan

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The effect of general versus spinal anesthesia on perioperative innate immune function in patients undergoing total hip arthroplasty by Lotte M. C. Jacobs, Veerle Bijkerk, Lucas T. van Eijk, Leo A. B. Joosten, Christiaan Keijzer, Jetze Visser, Michiel C. Warlé

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NMO-IgG and AQP4 Peptide Can Induce Aggravation of EAMG and Immune-Mediated Muscle Weakness by Tehila Mizrachi, Livnat Brill, Malcolm Rabie, Yoram Nevo, Yakov Fellig, Mayan Zur, Dimitrios Karussis, Oded Abramsky, Talma Brenner, Adi Vaknin-Dembinsky

“…To verify whether coexisting autoimmune disease may exacerbate experimental autoimmune MG, we tested whether active immunization with AQP4 peptides or passive transfer of NMO-Ig can affect the severity of EAMG. …”
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In vitro triazophos suppresses innate and cell-mediated immune responses of lymphoid organs in snakehead fish, Channa punctatus by Rakesh Kumar Chandra, Ajay Kumar Bhardwaj, Neha Gupta, Devendra Kumar Patel, Manish Kumar Tripathi

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Cytosolic DNA composition is determined by genomic instability mechanism and regulates dendritic cell-mediated anti-tumor immunity by Shayla R. Mosley, Angie Chen, David N.W. Doell, Siwon Choi, Courtney Mowat, Felix Meier-Stephenson, Vanessa Meier-Stephenson, Kristi Baker

“…Sequencing indicates that MSI cyDNA is enriched in microsatellites, which, upon DC uptake, induce anti-tumor immunity in a manner consistent with clinical MSI CRCs. …”
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Gut Microbiota–Tumor Microenvironment Interactions: Mechanisms and Clinical Implications for Immune Checkpoint Inhibitor Efficacy in Cancer by Said SS, Ibrahim WN

“…Emerging evidence suggests that the gut microbiota plays a pivotal role in modulating immune responses at the tumor site and may even influence treatment outcomes in cancer patients receiving ICIs. …”
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Probiotics Can Boost the Antitumor Immunity of CD8+T Cells in BALB/c Mice and Patients with Colorectal Carcinoma by Jie Mao, Shu-Ze Zhang, Peng Du, Zhi-Bin Cheng, Huan Hu, Shi-Yao Wang

“…The drug resistance and the immune suppression in the tumor microenvironment are important factors affecting tumor progression. …”
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Effect of RAS mutations and related immune characteristics on the prognosis of patients with MSI-H/dMMR colorectal cancer by Yupeng Jiang, Yuyao Liu, Hong Huang, Tiantian Zhao, Zengyi Zhao, Yawen Gao

“…Abstract Purpose Microsatellite high instability/deficient mismatch repair (MSI-H/dMMR) colorectal cancer (CRC) has an active tumor microenvironment, rendering it more sensitive to immune checkpoint inhibitors. Given that studies involving patients with MSI-H colorectal cancer with RAS mutations are scarce, we explored the effect of RAS mutations on the TME in patients with MSI-H/dMMR cancer and identified potential prognostic factors. …”
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