Is differential cleaning needed for SARS-CoV-2 beyond standard procedures? A systematic review by Uduak Okomo, Ememobong N. Aquaisua, Osamagbe Asemota, Deborah Ndukwu, Josephine E. Egbung, Ekpereonne B. Esu, Olabisi A. Oduwole, John E. Ehiri

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Development of ptxD/Phi as a new dominant selection system for genetic manipulation in Cryptococcus neoformans by Muthita Khongthongdam, Tanaporn Phetruen, Sittinan Chanarat

“…Taken together, the ptxD/Phi system provides a robust and versatile tool for genetic manipulation in C. neoformans, facilitating further research into its biology and pathogenicity.IMPORTANCECryptococcus neoformans is a type of fungus that can cause serious illnesses in people who have weakened immune systems, like those with HIV/AIDS. To better study this fungus and find new treatments, scientists need tools to change its genes in precise ways. …”
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Circular RNA encoded by PPARG in the peripheral blood and a lipopolysaccharide-induced cardiomyocyte inflammation model is identified as a marker of fulminant myocarditis by Shasha Huang, Shumin He, Fei Xiao, Yang Zhou, Su Lyu

“…GO and KEGG analysis revealed that the genes encoding the dysregulated circRNAs were associated with various biological functions related to the risk of FM development, including infectious diseases, the immune system, and signal transduction. The high expression of hsa_circ_0064338 (circ_PPARG) was confirmed in both the myocardial cell inflammation model and peripheral blood from a large sample of FM patients. …”
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Doxycycline Usage for Prevention of Leptospirosis among Farmers and Reasons for Failure to Use Chemoprophylaxis: A Descriptive Study from Southern Sri Lanka by C. L. Fonseka, B. N. Vidanapathirana, C. M. de Silva, A. A. B. B. Athukorala, P. R. Goonawardena, A. P. Karunathilake, I. H. Rajapakse, A. S. Dissanayake

“…Themes responsible for non-usage were elicited such as lack of awareness of chemoprophylaxis usage, false sense of security from the disease by perceived “immunity” due to prolong exposure or due to low prevalence of disease, lack of motivation, lack of availability of medication, and fear of side effects. …”
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Segmental analysis of human hair reveals intra-annual variation in 25(OH)D3 concentrations in modern and archaeological individuals by Kate Britton, Orsolya Czére, Eléa Gutierrez, Linda M. Reynard, Eamon Laird, Gary Duncan, Baukje de Roos

“…Abstract Vitamin D is essential for healthy skeletal growth and is increasingly recognised for its role in chronic disease development, inflammation and immunity. 25-hydroxyvitamin D3 (25(OH)D3) concentrations are an indicator of vitamin D status and are normally analysed in plasma or serum samples in clinical settings, while archaeological studies rely on the identification of skeletal markers of vitamin D deficiency, such as rickets. …”
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Exposure to high-temperature and high-humidity environments associated with cardiovascular mortality by Yalan Wu, Xiangrong Feng, Jinmei Li, Mengjun Li, Yao Wang, Weihui Lu, Huanhuan Luo

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hCTLA4-Gene-Modified Human Bone Marrow-Derived Mesenchymal Stem Cells (hBMMSCs) Maintain POSTN Secretion to Enhance the Migration Capability of Allogeneic hBMMSCs through the Integ... by Lei Song, Fei Zhang, Rui Zhou, Jun Xiao, Lei He, Fei Dai

“…In conclusion, hCTLA4-gene-modified hBMMSCs maintain POSTN secretion to enhance the migration capability of allogeneic hBMMSCs through the integrin αvβ3/FAK/ERK signaling pathway in the T cell immune activation environment.…”
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Changes in Techno-Functional Characteristics of Cow Colostrum Powder Prepared by Freeze Drying by Anamika Das, Raman Seth, Ayon Tarafdar, Swarnima Dey, Yogesh Kumar, Ranjna Sirohi

“…In freeze-dried bovine skimmed colostrum powder (BSCP) and bovine colostrum whey powder (BCWP), IgG emerged as the highest fraction among immune factors, whereas in growth factors, insulin-like growth factor 1(IGF1) and transforming growth factor β2 (TGFβ2) were found in large proportion as compared to insulin-like growth factor 2 (IGF2) and transforming growth factor β1 (TGFβ1). …”
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Anti-GAPDH Autoantibody Is Associated with Increased Disease Activity and Intracranial Pressure in Systemic Lupus Erythematosus by Jingjing Sun, Xue Li, Haotian Zhou, Xiaoyun Liu, Jingjing Jia, Qizhi Xie, Sijia Peng, Xiaolin Sun, Qingwen Wang, Li Yi

“…Systemic lupus erythematosus (SLE) is an immune disease characterized by multiorgan involvement. …”
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Reversal and prevention of deregulated autophagy in cutaneous autoimmune disorders—a pilot study on vitiligo with nutrigenomics based approach of “Maximum Nutrition and Minimum Med... by Suruchi Garg, Murlidhar Rajagopalan, Anupa Mary George, Hemangi Parwani, Titiksha Hans

“…It was aimed to reverse the self-destruction/deregulated autophagy by providing early morning, low carb-high protein nutrition, and correcting underlying micronutrient deficiency and studying its effect on reducing auto-immunity and eventually reducing disease burden and recurrence. …”
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Mono-allelic epigenetic regulation of polycistronic transcription initiation by RNA polymerase II in Trypanosoma brucei by Rudo Kieft, Laura Cliffe, Haidong Yan, Robert J. Schmitz, Stephen L. Hajduk, Robert Sabatini

“…Trypanosoma brucei brucei is unable to infect humans because of its susceptibility to an innate immune complex, trypanosome lytic factor (TLF) in the circulation of humans. …”
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Determination of antioxidant and phytochemical properties of premix extract of brown macroalgae Padinaaustralis, Sargassum licifolium and Stoechospermum marginatum from Chabahar co... by Paria Akbary

“…Like other organisms, polyphenols have beneficial properties such as antimicrobial and antioxidant properties that improve growth performance, nutrient utilization, immunity, and disease resistance. The aim of this study was to investigate the phytochemical compounds (sterol, phenol and flavonoids) and grinding each of the macroalgae by an electric mill (Moulinex model), antioxidant activity (diphenylpicryl hydrazyl (DPPH)) of premix extracts of brown macroalgae Padina australis, Sargassum ilicifolium and Stoechospermum marginatum.Materials and methods: Brown macroalgae Sargassum ilicifolium, Nizimuddinia zanardini, Cystoseria indica, Padina australis and Stoechospermum marginatum were collected from Chabahar shores during low tide in December 2022 and after being transported to the laboratory, they were rinsed with freshwater to remove debris. …”
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The effect of SARS-CoV-2 Omicron BA. 5.2 infection on perioperative physiological indicators in orthopedic patients by Hao Wu, JunZhe Yang, YuQin Yan, Xiao Hu, BiXi Li, PengFei Cheng, XiaoYang Song

“…Changes in the following factors were compared within and between the two groups: heart rate, mean arterial pressure, oxygenation index at the time of entry into the operating room, incision of the skin and exit from the operating room and the neutrophil‒lymphocyte ratio (NLR), platelet‒lymphocyte ratio (PLR), systemic immune inflammation index (SII), D-dimer level, and fibrinogen degradation product (FDP) level. …”
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Microbial keratitis in Southern Malawi: a microbiological pilot study by Timothy Neal, Dean Everett, Stephen B Kaye, Alistair Darby, Moira Gandiwa, Shaffi Mdala, Caroline E Corless, Rose Herbert, Nicholas A V Beare, Tobi F Somerville, Thokozani Zungu, Malcolm J Horsburgh, Petros C Kayange

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SUMO modified ETV1 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by facilitating CCL2 transcription in esophageal squamous cell carcinoma ce... by Tianci Han, Xiaoqi Guo, Junwei Xie, Wei Tong, Liang Zhang

“…Methods Gene expression and immune infiltration in ESCC samples from the Cancer Genome Atlas (TCGA) were analyzed. …”
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Diagnostic value of interleukins 23 and 17 in the assessment of ulcerative colitis severity by M.V. Stoikevych, O.M. Tatarchuk, T.S. Tarasova

“…Ulcerative colitis (UC) is a chronic bowel disease with a complex aetiology that includes immune, genetic and environmental factors. Its progression and severity vary greatly, suggesting that different cytokine pathways may be responsible for the heterogeneity of clinical outcomes. …”
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Genome stability of the vaccine strain VAC∆6 by R. A. Maksyutov, S. N. Yakubitskiy, I. V. Kolosova, T. V. Tregubchak, A. N. Shvalov, E. V. Gavrilova, S. N. Shchelkunov

“…Due to cessation of mass smallpox vaccination in 1980, the collective immunity of humans against orthopoxvirus infections has virtually been lost. …”
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Combining systemic inflammation biomarkers with traditional prognostic factors to predict surgical site infections in elderly hip fracture patients: a risk factor analysis and dyna... by Yuhui Guo, Chengsi Li, Haichuan Guo, Peiyuan Wang, Xuebin Zhang

“…Multivariable analysis identified traditional prognostic factors older age (OR = 1.08, 95% CI 1.04–1.12), ASA class III-IV (OR = 2.46, 95% CI 1.32–4.56), surgical delay ≥ 6 days (OR = 3.59, 95% CI 1.36–9.47), surgical duration > 180 min (OR = 2.72, 95% CI 1.17–6.35), and systemic inflammation biomarkers Platelet-to-lymphocyte ratio (PAR) ≥ 6.6 (OR = 2.25, 95% CI 1.17–4.33) and Systemic Immune-Inflammation Index (SII) ≥ 541.1 (OR = 2.24, 95% CI 1.14–4.40) as independent predictors of SSI. …”
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Prevalence of neutropenia in the U.S. among reproductive-aged women: a population-based analysis of NHANES 2013–2020 by Junfeng Chen, Shuangna Song, Yiran Li

“…Neutrophils, despite their established significance as vital players in both inflammatory and immune processes, have been studied scarcely in terms of their effect on female infertility. …”
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Altered CD73-Adenosine Signaling Linked to Infection in Patients undergoing hemodialysis by Xiang F, Zhang Z, Nie Y, Cao X, Li Y, Chen X, Gong S, Zou J, Teng J, Ding X, Shen B

“…Altered CD73-adenosine signaling likely plays a substantial role in immune dysfunction in CKD. Keywords: adenosine, CD73, hemodialysis, infection, T cell dysfunction…”
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