Development of Predictive Models for Progression from Diabetic Kidney Disease to End-Stage Renal Disease in Type 2 Diabetes Mellitus: A Retrospective Cohort Study by Hu H, Mu X, Zhao S, Yang M, Zhou H

“…Time-dependent receiver operating characteristic (ROC) was used to evaluate prediction performance, and the area under the curve (AUC) was calculated to assess the model’s accuracy.Results: The Cox regression model developed for the 555 patients clinically diagnosed with DKD identified 5 predictors (body mass index (BMI), estimated glomerular filtration rate (eGFR), 24-hour urinary total protein (UTP), systemic immune-inflammatory index (SII), and controlling nutritional status (CONUT), whereas the Competing risks model included 4 predictors (BMI, eGFR, UTP, CONUT). …”
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Analysis of resistance to stem rust and identification of <i>Sr</i> genes in introgressive lines of spring bread wheat by O. A. Baranova, S. N. Sibikeev, E. A. Konkova

“…They can be used in Russian breeding programs for immunity.…”
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Comparison of Perinatal, Newborn, and Audiometry Results of COVID-19 Pregnant Women by Mehmet Yilmaz, Şerif Aksin, Deniz Balsak, Fazil Avci, Osman Özdoğru, Bekir Helvacıoğlu, Mahmut Erdemoğlu, Yasemin Aboalhasan, Gülsüm Doğan

“…There are studies on the perinatal outcomes of COVID-19, but the audiometric effects of the maternal immune system against COVID-19 in the newborn are not clear. …”
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Traditional Chinese medicine trade among RCEP countries: structural characteristics and determinants by Yue Fang, Yue Fang, Meng Xue Tang, Xu Liu

“…Tonifying TCM products with antioxidant and immune-boosting properties are more widely recognized in international markets.ConclusionRCEP has established an excellent trade platform for the export of TCM. …”
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RETRACTED: Efficacy of Vanadyl Sulfate and Selenium Tetrachloride as Anti-Diabetic Agents against Hyperglycemia and Oxidative Stress Induced by Diabetes Mellitus in Male Rats by Fawziah A. Al-Salmi, Reham Z. Hamza

“…The use of metals in medicine has grown in popularity in clinical and commercial settings. In this study, the immune-protecting effects and the hypoglycemic and antioxidant activity of vanadyl sulfate (VOSO₄) and/or selenium tetrachloride (Se) on oxidative injury, DNA damage, insulin resistance, and hyperglycemia were assessed. …”
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Modern trends in breeding and genetic improvement of sunflower varieties and hybrids at VNIIMK by V. M. Lukomets, M. V. Trunovа, Ya. N. Demurin

“…Within the framework of breeding for immunity, eight hybrids and one variety have been produced. …”
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A systematic review of circulating IP-10/CXCL10 in patients with Plasmodium infections in relation to disease severity by Manas Kotepui, Aongart Mahittikorn, Frederick Ramirez Masangkay, Kwuntida Uthaisar Kotepui

“…Abstract Interferon γ-induced protein 10 kDa (IP-10) or C–X–C motif chemokine 10 (CXCL10) is produced and secreted from specific leukocytes such as neutrophils, eosinophils, and monocytes, which play key roles in the immune response to Plasmodium infections. This systematic review aimed to collate and critically appraise the current evidence on IP-10 levels in malaria patients. …”
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Infant Feeding Practices of HIV Positive Mothers and Its Association with Counseling and HIV Disclosure Status in Ethiopia: A Systematic Review and Meta-Analysis by Getaneh Mulualem Belay, Chalachew Adugna Wubneh

“…However, in the era of Human Immune Deficiency Virus (HIV) infection, feeding practice is a challenge due to mother-to-child HIV transmission. …”
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A multi-strain human skin microbiome model provides a testbed for disease modeling by Angela L. Maloney, Tyler Crawford, Jordan Hurlbut, Monica Martinez, Thomas J. Mulhern, Elizabeth L. Wiellette, Else M. Vedula, Vidhya Vijayakumar

“…The skin microbiome plays a critical role at the interface between the human epidermis and the environment, providing colonization resistance against pathogenic strains, training host immunity, and supporting epithelial turnover. Inversely, dysbiotic skin microbiome states are associated with skin disease, particularly inflammatory conditions such as atopic dermatitis and psoriasis. …”
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In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies by Aimee E. Mattei, Andres H. Gutierrez, Soorya Seshadri, Jacob Tivin, Matt Ardito, Amy S. Rosenberg, William D. Martin, Anne S. De Groot

“…Even if the source of a given biologic is ‘fully human’, T cell epitopes that are contained in the sequences of the biologic may activate the immune system, enabling the development of anti-drug antibodies that can reduce drug efficacy and may contribute to adverse events. …”
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Crotonylation-Related Prognostic Model of Esophageal Squamous Cell Carcinoma Based on Transcriptome Analysis and Single-Cell Sequencing Analysis by Lin RY, Chen RP, Lin FQ

“…Functional enrichment and immune infiltration analyses were performed using the prognostic genes. …”
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Differential Regulation of NK Cell Receptors in Acute Lymphoblastic Leukemia by Le Jie Lee, Norfarazieda Hassan, Siti Zuleha Idris, Suresh Kumar Subbiah, Heng Fong Seow, Norhafizah Mohtaruddin, Kian Meng Chang, Raudhawati Osman, Hishamshah Mohd Ibrahim, Sheila Nathan, Maha Abdullah

“…Concepts in cancer control and influence of sex require further investigation to improve successful mobilization of immune cells in cancer patients. Acute lymphoblastic leukemia (ALL) is a hematological malignancy mainly of B cell (B-ALL) and T cell (T-ALL) subtypes. …”
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Multidrug Resistant Enteric Bacteria from Cancer Patients Admitted in Douala Laquintinie Hospital, Littoral Region of Cameroon by Michael F. Kengne, Ornella D. Tsobeng, Ballue S. T. Dadjo, Victor Kuete, Armelle T. Mbaveng

“…Patients with cancer have weakened immune systems, making them more vulnerable to infections. …”
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Antiviral Drugs and Vaccines for Omicron Variant: A Focused Review by Nidhi Garg, Ananya Sree Kunamneni, Pankaj Garg, Sandeep Sharma, Divakar Sharma, Adinarayana Kunamneni

“…This probably explains the reason for worldwide breakthrough infections with the Omicron variant with waning immunity. The neutralizing antibody response against Omicron elicited by the bivalent vaccine is superior to that of the ancestral Wuhan strain, without any safety concerns. …”
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Clinical Holistic Medicine: A Pilot Study on HIV and Quality of Life and a Suggested Cure for HIV and AIDS by Søren Ventegodt, Trine Flensborg-Madsen, Niels Jørgen Andersen, Mohammed Morad, Joav Merrick

“…This study was undertaken to examine the association between the immunological impact of HIV (measured by CD4 count) and global self-assessed quality of life (QOL) (measured with QOL1) for people suffering from HIV, to see if the connection was large and statistically strong enough to support our hypothesis of a strong QOL-immunological connection through the nonspecific, nonreceptor-mediated immune system, and thus to give a rationale for a holistic cure for HIV. …”
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NK-92 cells activated by IL-2 inhibit the progression of endometriosis in vitro by Jun Yao, Li-jiao Zhang, Zhe Zhou, Mao-fang Hua

“…Background Interleukin (IL)-2 is a key cytokine capable of modulating the immune response by activating natural killer (NK) cells. …”
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Design and expression of a chimeric recombinant antigen (SsIR-Ss1a) for the serodiagnosis of human strongyloidiasis: Evaluation of performance, sensitivity, and specificity. by Mostafa Omidian, Zohreh Mostafavi-Pour, Marzieh Asadi, Meysam Sharifdini, Navid Nezafat, Ali Pouryousef, Amir Savardashtaki, Mortaza Taheri-Anganeh, Fattaneh Mikaeili, Bahador Sarkari

“…The present study aimed to design and produce a chimeric recombinant antigen from Strongyloides stercoralis immunoreactive antigen (SsIR) and Ss1a antigens, using immune-informatics approaches, and evaluated its diagnostic performance in an ELISA system for the diagnosis of human strongyloidiasis.…”
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The clinical journey of belantamab mafodotin in relapsed or refractory multiple myeloma: lessons in drug development by Pralay Mukhopadhyay, Hesham A. Abdullah, Joanna B. Opalinska, Prani Paka, Eric Richards, Katja Weisel, Suzanne Trudel, Maria-Victoria Mateos, Meletios Athanasios Dimopoulos, Sagar Lonial

“…It considers how incorporating longer follow-up in DREAMM-3 may have better captured the clinical benefits of belantamab mafodotin, particularly given its multimodal, immune-related mechanism of action with responses deepening over time. …”
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Aspartate aminotransferase to platelet ratio correlates with poor prognosis and metabolic alterations in Dabie bandavirus infection by Chunxia Guo, Ruixue Li, Xia Wang, Xiulan Peng

“…Receiver operating characteristic analysis showed the predictive performance of APRI for SFTS prognosis is 0.77, with a 95% CI of 0.73–0.80, which was superior to NLR (area under the curve (AUC): 0.65), platelet-to-lymphocyte ratio (AUC: 0.54), and systemic immune-inflammation index (AUC: 0.58). The prognostic value and predictive performance of APRI were more substantial after PSM than before PSM. …”
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Effect of Zbtb33 gene knockout and bacterial lipopolysaccharide on home cage behavior in mice by N. V. Khotskin, I. E. Sorokin, E. A. Kulikova, A. V.  Kulikov

“…The aim of this study is to elucidate the role that Kaiso plays in regulating daily activity, as well as the behavioral response to stimulation of nonspecific immunity. Experiments were performed on adult male mice with Zbtb33 gene knockout (KO) and animals of the C57BL/6 line (wild type, WT). …”
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