Advancing immunosuppression in liver transplantation: the role of regulatory T cells in immune modulation and graft tolerance by Ji Won Han, Su-Hyung Park

“…Regulatory T cells (Tregs) represent a promising target for inducing immune tolerance in LT, with the potential to reduce or eliminate the need for life-long immunosuppression. …”
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Revolutionizing ESCC prognosis: the efficiency of tumor-infiltrating immune cells (TIIC) signature score by Haixia Wang, Shaowei Ma, Zixin Yang, Ren Niu, Haiyong Zhu, Shujun Li, Shaolin Gao, Zhirong Li, Yanhua Tian

Subjects: “…Tumor-infiltrating immune cells (TIIC)…”
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Characteristics and clinical significance of immune cells in omental milky spots of patients with gastric cancer by Yasunobu Mano, Yasunobu Mano, Yuka Igarashi, Yuka Igarashi, Keisuke Komori, Keisuke Komori, Itaru Hashimoto, Itaru Hashimoto, Hayato Watanabe, Kosuke Takahashi, Kazuki Kano, Hirohito Fujikawa, Takanobu Yamada, Hidetomo Himuro, Hidetomo Himuro, Taku Kouro, Taku Kouro, Feifei Wei, Feifei Wei, Kayoko Tsuji, Kayoko Tsuji, Shun Horaguchi, Shun Horaguchi, Shun Horaguchi, Mitsuru Komahashi, Mitsuru Komahashi, Mitsuru Komahashi, Takashi Oshima, Tetsuro Sasada, Tetsuro Sasada

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Assessing hemorrhagic risks in combination therapy: implications of angiogenesis inhibitors and immune checkpoint inhibitors by Yuhui Yang, Yuhui Yang, Yuhui Yang, Pingping Long, Pingping Long, Ying Tuo, Ying Tuo, Xiaoxiao Wang

Subjects: “…immune checkpoint inhibitors…”
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The genomic architecture of circulating cytokine levels points to drug targets for immune-related diseases by Marek J. Konieczny, Murad Omarov, Lanyue Zhang, Rainer Malik, Tom G. Richardson, Sebastian-Edgar Baumeister, Jürgen Bernhagen, Martin Dichgans, Marios K. Georgakis

“…Abstract Circulating cytokines orchestrate immune reactions and are promising drug targets for immune-mediated and inflammatory diseases. …”
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The Emerging Role of GC-MSCs in the Gastric Cancer Microenvironment: From Tumor to Tumor Immunity by Zhaoji Pan, Yiqing Tian, Guoping Niu, Chengsong Cao

“…In this review, we mainly describe and discuss recent advances in our understanding of the emerging role of gastric cancer-derived MSC-like cells (GC-MSCs) in regulating gastric cancer progression and development, as well as the bidirectional influence between GC-MSCs and immune cells of the tumor microenvironment. Moreover, we also discuss the potential biomarker and therapeutic role of GC-MSCs. …”
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Mutation of isocitrate dehydrogenase indicates favorable outcomes in pan-cancer immune checkpoint blockade by Zhiyang Huang, Yingying Li, Hong Zhao, Bin Zhao

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Phenotypic insights into genetic risk factors for immune-related adverse events in cancer immunotherapy by Haochuan Ma, Dili Song, Haibo Zhang, Taidong Li, Xing Jin

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Differences in the Antigens of Helicobacter pylori Strains Influence on the Innate Immune Response in the In Vitro Experiments by Miha Skvarc, Andreja Natasa Kopitar, Janko Kos, Natasa Obermajer, Bojan Tepes

“…The immune response to Helicobacter pylori importantly determines the pathogenesis of infection as well as the success of antibiotic eradication of the bacteria. …”
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Inflammatory disease progression shapes nanoparticle biomolecular corona-mediated immune activation profiles by Jacob R. Shaw, Nicholas Caprio, Nhu Truong, Mehari Weldemariam, Anh Tran, Nageswara Pilli, Swarnima Pandey, Jace W. Jones, Maureen A. Kane, Ryan M. Pearson

“…This study investigates how the progression of acute systemic inflammatory disease influences NP corona compositions and the corresponding effects on innate immune cell interactions, phenotypes, and cytokine responses. …”
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Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the application by Maja Kozarski, Anita Klaus, Leo van Griensven, Dragica Jakovljevic, Nina Todorovic, Wan Abd Al Qadr Imad Wan-Mohtar, Jovana Vunduk

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A pair of promising immune checkpoints PSGL-1 and VISTA from immunotolerance to immunotherapy by Manqing Peng, Xiaofang Lu, Junshuang Guo, Xiangli Yin, Jing Zhang, Xin Li, Yizhou Zou

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Effects of Red Clover Isoflavones on Growth Performance, Immune Function, and Cecal Microflora of Mice by Rongrong Guo, Xuqin Song, Xiaodie Li, Cheng Zeng, Ying Chen, Chunjie Li, Jian Yang, Deyuan Ou

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Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator by Joao Luiz Mendes Wanderley, Jaqueline França Costa, Valéria Matos Borges, Marcello Barcinski

“…Here we discuss the possible role of phosphatidylserine exposure by these parasites as a main regulator of the mechanism underlying subversion of the immune system at different steps during the infection.…”
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Immune imbalance in the pre-ovulatory follicular microenvironment of overweight and obese women during IVF by Yang Liu, Yiran Zhao, Chengliang Zhou, Hong Zhu, Jiexue Pan, Jing Fu, Hefeng Huang, Hui Lin, Li Jin

“…Conclusion Overweight and obesity can disrupt immune hemostasis in the pre-ovulatory follicular microenvironment, potentially leading to adverse effects on assisted reproductive outcomes.…”
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Immune Activation, Immunosenescence, and Osteoprotegerin as Markers of Endothelial Dysfunction in Subclinical HIV-Associated Atherosclerosis by Alessandra D’Abramo, Maria Antonella Zingaropoli, Alessandra Oliva, Claudia D’Agostino, Samir Al Moghazi, Giulia De Luca, Marco Iannetta, Claudio Maria Mastroianni, Vincenzo Vullo

“…Subjects with pathological c-IMT exhibited higher CD8+ immune activation and immunosenescence and OPG levels than subjects with normal c-IMT. …”
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A delay-differential equation model of HIV related cancer--immune system dynamics by Urszula Foryś, Jan Poleszczuk

“…In the human body, the appearance of tumor cells usually turns on the defensive immune mechanisms. It is therefore of great importance to understand links between HIV related immunosuppression and cancer prognosis. …”
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DNA methylation and immune evasion in triple-negative breast cancer: challenges and therapeutic opportunities by Wen-yu Cai, Xin-xian Cai, Yi-ran Fei, Rui Ye, Ding-ming Song, Dan Hu, Wan-wan Zhang, Ming-fei Xia, Xiao-xiao Yang

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Rheumatoid arthritis associated cytokines and therapeutics modulate immune checkpoint receptor expression on T cells by Dana Emerson, Eve Merriman, Pia P. Yachi

“…IntroductionWe investigated the impact of rheumatoid arthritis (RA) associated cytokines and standard of care (SOC) RA therapeutics on immune checkpoint receptor (IR) expression on T cells to gain insights to disease pathology and therapeutic avenues.MethodsWe assessed IR expression by flow cytometry on T cell receptor activated T cells cultured in the presence of exogenously added single cytokines or RA patient synovial fluid. …”
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Predictions of Acute Relapse of Crohn’s Disease: A Study of Host Nonspecific Immune Reactivity by E René

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