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8601
Phytosanitary monitoring of the narrow-leaved lupine collection of VIR in the northwest of Russia
Published 2021-10-01“…Studying the species composition of pathogens and searching for source material are the necessary stages of plant breeding for immunity.Materials and methods. A set of 101 accessions of L. angustifolius from the VIR collection were studied in the northwest of the Russian Federation (Pushkin, St. …”
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8602
Gene Expression Profiling in Dermatitis Herpetiformis Skin Lesions
Published 2012-01-01“…Consistently with the autoimmune origin of DH, functional classification of the differentially expressed genes (DEGs) indicates a B- and T-cell immune response (LAG3, TRAF5, DPP4, and NT5E). In addition, gene modulation provides evidence for a local inflammatory response (IL8, PTGFR, FSTL1, IFI16, BDKRD2, and NAMPT) with concomitant leukocyte recruitment (CCL5, ENPP2), endothelial cell activation, and neutrophil extravasation (SELL, SELE). …”
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8603
Interference in Macrophage Balance (M1/M2): The Mechanism of Action Responsible for the Anti-Inflammatory Effect of a Fluorophenyl-Substituted Imidazole
Published 2024-01-01“…Hence, macrophages, a critical key in both innate and acquired immunity, have been presented as an alternative target for the development of new medicines. …”
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8604
Cytokines and Metabolic Patterns in Pediatric Patients with Critical Illness
Published 2010-01-01“…It is not known if cytokines, which are cell-derived mediators released during the host immune response to stress, affect metabolic response to stress during critical illness. …”
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8605
Public safety in the conditions of martial law and mental warfare
Published 2022-09-01“…The mental war for people’s minds means that we must make people immune to the enemy’s “new weapons”, make the enemy’s rules ineffective and carefully leave their field, and in the long run, drag it into ours. …”
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8606
Mechanisms of (Fisch.) Bge. var. mongholicus (Bge.) Hsiao (huang qi) and (Oliv.) Diels (dang gui) in Ameliorating Hypoxia and Angiogenesis to Delay Pulmonary Nodule Malignant Tra...
Published 2025-01-01“…Modern pharmacological studies have demonstrated that AR and ARS possess immune-enhancing, anti-tumor, anti-inflammatory, and anti-angiogenic properties. …”
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8607
Exploring the mechanism of berberine treatment for atherosclerosis combined with non-alcoholic fatty liver disease based on bioinformatic and experimental study.
Published 2024-01-01“…Function analysis revealed that the implicated genes were significantly involved in pathways like cytokine-cytokine receptor interaction, chemokine signaling, and IL-17 signaling pathway, suggesting their role in inflammation and immune responses. Single cell validation identified six key genes: dual specificity phosphatase 6 (DUSP6), chemokine ligand 3 (CCL3), complement component 5a receptor 1 (C5AR1), formyl peptide receptor 1 (FPR1), myeloid nuclear differentiation antigen (MNDA), and proviral integration site of murine 2(PIM2). …”
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8608
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8609
The level of IL-12, IL-10, IL-4, and MMP-13 in cutaneous leishmaniasis patients
Published 2024-10-01“…The disease disproportionately impacts those residing in economically disadvantaged regions and is closely linked to factors such as inadequate nutrition, population displacement, substandard living conditions, and compromised immune systems. Objectives: Investigating the most important immunological changes associated with infection in patients with CL by measuring the levels of some cellular kinetics interleukins-12 (IL-12), IL-10, IL-4, and human matrix metalloproteinase-13 (MMP-13). …”
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8610
Structural characterization of two γδ TCR/CD3 complexes
Published 2025-01-01“…Abstract The T-cell receptor (TCR)/CD3 complex plays an essential role in the immune response and is a key player in cancer immunotherapies. …”
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8611
Recurrent Herpes Zoster Ophthalmicus Preceded by Anabolic Steroids and High-Dose L-Arginine
Published 2020-01-01“…Anabolic steroids have also been demonstrated by various studies to negatively affect cell-mediated immunity necessary to prevent viral infection. Thus, it is possible that anabolic steroids in conjunction with increased L-arginine intake may have precipitated a recurrent HZO in a previously healthy, immunocompetent individual.…”
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8612
Addition of garlic (Allium sativum) extract in fry as immunostimulant on survival and blood profile of pomfret fish (Colossoma macropomum)
Published 2025-01-01“…Using immunostimulants to control bacterial diseases can enhance the function of the immune system. Garlic is a natural ingredient that can serve as an effective immunostimulant. …”
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8613
Trypsin inhibitor activity in representatives of the genus Hedysarum (Fabaceae): the polyvariance of seasonal dynamics in Southern Siberia
Published 2020-10-01“…Trypsin-inhibiting activity (TIA) is one of the factors of plant immunity. This factor provides the presence of general non-specific systemic resistance. …”
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8614
The results of a comprehensive study of spring wheat accessions from the VIR collection according to their breeding characteristics
Published 2025-01-01“…Source material for breeding new high-intensity immune cultivars in Kirov Province was selected for a set of valuable agronomic and biological characteristics.…”
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8615
A new perspective on cardiovascular function and dysfunction during endurance exercise: identifying the primary cause of cardiovascular risk
Published 2024-04-01“…The review highlighted that high oxidative stress (due to high levels of catecholamines, shear stress, immune system activation, and renal dysfunction) leads to a rise in platelet aggregation during endurance exercise. …”
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8616
Probiotics in the Complex Treatment of Various Diseases of the Gastrointestinal Tract
Published 2020-04-01“…It has been confirmed that the microbiome participates in the development of inflammatory and functional diseases of the gastrointestinal tract, affects the immune system, central nervous system and mental status. …”
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8617
A Rare Case of Large-Vessel Vasculitis following Checkpoint Inhibitor Therapy and Pegfilgrastim
Published 2022-01-01“…Checkpoint inhibitors (CPIs) and pegfilgrastim, a long-acting growth factor agent, are vital components of current cancer treatments. Immune-related adverse events (irAEs) such as colitis and pneumonitis are well-established toxicities associated with CPI therapy. …”
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8618
Investigating the functional and structural effect of non-synonymous single nucleotide polymorphisms in the cytotoxic T-lymphocyte antigen-4 gene: An in-silico study.
Published 2025-01-01“…The cytotoxic T-lymphocyte antigen-4 (CTLA4) is essential in controlling T cell activity within the immune system. Thus, uncovering the molecular dynamics of single nucleotide polymorphisms (SNPs) within the CTLA4 gene is critical. …”
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8619
Long-Term GAD-alum Treatment Effect on Different T-Cell Subpopulations in Healthy Children Positive for Multiple Beta Cell Autoantibodies
Published 2022-01-01“…The Diabetes Prevention–Immune Tolerance 2 (DiAPREV-IT 2) clinical trial enrolled 26 children between 4 and 13 years of age, positive for glutamic acid decarboxylase autoantibody (GADA) and at least one other autoantibody (insulin, insulinoma antigen-2, or zinc transporter 8 autoantibody (IAA, IA-2A, or ZnT8A)) at baseline. …”
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8620
Spirituality of HIV-infected female patients treated in a secondary care hospital in Thailand: a preliminary investigation
Published 2024-02-01“…Introduction Globally, acquired immune deficiency syndrome (AIDS) and human immunodeficiency virus (HIV) infection are major public health concerns. …”
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