Genetic Diversity of Toll-Like Receptors and Immunity to M. leprae Infection by Bryan E. Hart, Richard I. Tapping

“…Toll-like receptors (TLRs) have emerged as an essential family of innate immune pattern recognition receptors which play a pivotal role in host defense against microbes, including pathogenic strains of mycobacteria. …”
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Response to letter regarding “Plasma concentration of thrombopoietin in dogs with immune thrombocytopenia” by Marjory B. Brooks, James C. Brooks, Jim Catalfamo, Yao Zhu, Robert Goggs, Susanna Babasyan, Bettina Wagner, Dana H. LeVine

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The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines by Stefan Landgraeber, Marcus Jäger, Joshua J. Jacobs, Nadim James Hallab

“…In some people implant debris (particles and ions from metals) can influence the adaptive immune system as well, giving rise to the concept of metal sensitivity. …”
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The epidermal lipid-microbiome loop and immunity: Important players in atopic dermatitis by Junchao Wu, Lisha Li, Tingrui Zhang, Jiaye Lu, Zongguang Tai, Quangang Zhu, Zhongjian Chen

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Immunotherapeutic Potential of Lactobacillus Species as Immune Checkpoint Inhibitors in Cancer Immunotherapy by Renukadevi J, Sam Helinto J, Prena D

“…These probiotics influence immune responses through interactions with immune cells such as dendritic cells, macrophages, and T cells. …”
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Paucity of viral infection symptoms in patients with immune-mediated inflammatory diseases by Carola Berking, Georg Schett, Andreas Ramming, Raja Atreya, Markus F Neurath, Bernhard Manger, Filippo Fagni, Arnd Kleyer, Milena L Pachowsky, Axel J Hueber, Stefan Kleinert, Karin Manger, Florian Schuch, Monika Ronneberger, David Simon, Michael Sticherling, Koray Tascilar, Christine Meder, Moritz Leppkes, Peter Dietrich, Verena Schoenau, Daniela Bohr, Fabian Hartmann, Selahattin Alp Temiz, Ioanna Minopoulou, Louis Schuster, Melek Yalcin Mutlu, Gerhard Kroenke, Till Orlemann, Johanna Mößner

“…Objectives Although patients with immune-mediated inflammatory diseases (IMID) are thought to be more susceptible to viral infections, it is unclear whether their presentation differs between patients with IMID and healthy controls. …”
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Comprehensive analysis of disulfidptosis-related genes and the immune microenvironment in heart failure by Linna Zhao, Juanjuan Zhang, Juanjuan Zhang, Qiuhang Song, Cheng Dai, Yiping Qin, Aiying Li, Aiying Li

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Tissue-resident immune cells: from defining characteristics to roles in diseases by Jia Li, Chu Xiao, Chunxiang Li, Jie He

“…Abstract Tissue-resident immune cells (TRICs) are a highly heterogeneous and plastic subpopulation of immune cells that reside in lymphoid or peripheral tissues without recirculation. …”
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Expression and Significance of Immune Checkpoints in Clear Cell Carcinoma of the Uterine Cervix by Liju Zong, Qianqian Zhang, Yuncan Zhou, Yujia Kong, Shuangni Yu, Jie Chen, Youzhong Zhang, Yang Xiang

“…Our study confirmed the expression of immune checkpoint proteins in cervical CCCs and indicated their nonredundant and complementary roles. …”
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Role of nasal microbiota in regulating host anti-influenza immunity in dogs by Jinzhu Geng, Yuhao Dong, Hao Huang, Xia Wen, Ting Xu, Yanbing Zhao, Yongjie Liu

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Based on the immune system: the role of the IL-2 family in pancreatic disease by Yuqing Zhu, Zheng Lu, Zhuo Wang, Jiao Liu, Ke Ning

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Editorial: Key players of the immune system in skin inflammation—allergy and autoimmunity by Laila Karra Khalil, Abhishek Asthana, Roopesh Singh Gangwar

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A Role for PPARγ in the Regulation of Cytokines in Immune Cells and Cancer by Xiao Yi Yang, Li Hua Wang, William L. Farrar

“…In addition to the well-studied effects of PPARγ on metabolism and cellular differentiation, abundant evidence suggests that PPARγ is an important regulator of the immune system and cancers. Since cytokines are not only key modulators of inflammation with pro- and anti-inflammatory functions but they also can either stimulate or inhibit tumor growth and progression, this review summarizes the role for PPARγ in the regulation of cytokine production and cytokine-mediated signal transduction pathways in immune cells and cancer.…”
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Inflammatory Response and Immune Regulation in Brain-Heart Interaction after Stroke by Lihua Zou, Ruquan Han

“…This review article summarizes the current understanding of inflammatory response and immune regulation in brain-heart interaction after stroke.…”
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A Case Report of Membranoproliferative Glomerulonephritis: Infection‐Related or Immune‐Related? by Ayman Azhary, Mohammed Taha, Nooh Mohamed Hajhamed, Salahaldeen Ismail Mohammed, Nouh Saad Mohamed, Waleed Azhary Sir Alkhatim

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The Impact of Immune System in Regulating Bone Metastasis Formation by Osteotropic Tumors by Lucia D’Amico, Ilaria Roato

“…Many studies report the importance of the immune system in the pathogenesis of bone metastasis. …”
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Distribution of bacterial DNA repair proteins and their co-occurrence with immune systems by Sumanth K. Mutte, Patrick Barendse, Pilar Bobadilla Ugarte, Daan C. Swarts

“…Our results imply that while certain DNA repair proteins and immune systems might function in conjunction, no immune system strictly relies on a specific DNA repair protein. …”
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T cell immune senescence is associated with frailty and sarcopenia in lung transplant candidates by Joanna M. Schaenman, MD, PhD, Harry Pickering, PhD, Elaine F. Reed, PhD, Maura Rossetti, PhD, Benjamin Seligman, MD, S. Samuel Weigt, MD, Michael Shino, MD, David Sayah, MD, PhD, John Belperio, MD, Ashley Hu, MD, Ashley Prosper, MD, Kathleen Ruchalski, MD, Abbas Ardehali, MD, Reshma Biniwale, MD

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Nanosystems for modulation of immune responses in periodontal therapy: a mini-review by Anirudh B. Acharya, Usha Hegde, Swetha Acharya

“…The current understanding of the pathogenesis of periodontitis has unraveled the importance of the inflammatory and immune reactions to combat periodontitis whose etiology is an overlap of microbial, genetic, and environmental factors in a susceptible host. …”
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Identification of hub biomarkers and immune cell infiltrations participating in the pathogenesis of endometriosis by Kang Li, Jiaxu Wang, Xuyue Liu, Yifei Dang, Kaiting Wang, Manyu Li, Xiaoli Zhang, Yuan Liu

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