The interplay between persistent pathogen infections with tumor microenvironment and immunotherapy in cancer by Si Chen, Caihong Yao, Na Tian, Chunying Zhang, Yuemei Chen, Xuting Wang, Yue Jiang, Tonghao Zhang, Tingting Zeng, Yali Song

“…Abstract Background Chronic infections by pathogenic microorganisms play a significant role in cancer development, disrupting the body's immune system and microenvironment. This interference impairs the body's ability to eliminate these microorganisms promptly, allowing them to persist by evading immune defenses. …”
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Modern concept of bacterial complications at liver cirrhosis by M. S. Zharkova, M. V. Mayevskaya, V. T. Ivashkin

“…These patients are more predisposed to infections than others hospital patients due to disorders of immune system along with bacterial translocation from intestine, that, in turn, depends on immune changes of the latter and bacterial overgrowth. …”
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Immune Tolerance Regulation Is Critical to Immune Homeostasis by Lei Han, Tianxiang Wu, Qin Zhang, Anning Qi, Xiaohui Zhou

“…In this review article, we summarized the main mechanisms that have been known to mediate immune tolerance so far, including endogenous immune tolerance, adaptive immune tolerance, other immune tolerance mechanisms, and the homeostasis of immune tolerance, identified the key factors that regulate immune tolerance, and provided new clues for immune system recovery in many autoimmune diseases, organ transplantation, and tumor therapy.…”
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HIV and the gut microbiome: future research hotspots and trends by Zhen Wu, Zhan-Peng Xie, Xin-Xin Cui, Xiang-Bin Sun, Fang-Yi Zhao, Nuo Wang, Yu Li, Yu Li, Yu Li, Haixia Wang, Haixia Wang, Haixia Wang, Li Zhang, Li Zhang, Li Zhang, Jing Shen, Fulei Chen, Haogang Sun, Jia He, Jia He, Jia He

“…BackgroundThe use of highly active antiretroviral therapy has transformed AIDS into a chronic infectious disease, but issues of chronic inflammation and immune system activation persist. Modulating the gut microbiome of patients may improve this situation, yet the specific association mechanisms between HIV and the gut microbiome remain unclear. …”
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Exosomes, their sources, and possible uses in cancer therapy in the era of personalized medicine by Tomas Zemanek, Lubos Danisovic, Andreas Nicodemou

“…Research has shown that exosomes have the dual ability to both activate and suppress the immune system. Their potential as anticancer vaccines arise from the capacity to carry antigens and major histocompatibility complex (MHC) molecules. …”
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Irritable Bowel and Bacterial Overgrowth Syndromes: a Bacterial Link Hypothesis of Functional Disease by K. V. Ivashkin, V. R. Grechishnikova, M. S. Reshetova, V. T. Ivashkin

“…SIBO may represent a "peripheral" mechanism of IBS, aside to nonspecific inflammation, increased epithelial permeability and local immune system activation. In various assays, the SIBO rate in IBS patients was 4-46% vs. 0-13% in an intact cohort. …”
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Implications of intratumoral microbiota in tumor metastasis: a special perspective of microorganisms in tumorigenesis and clinical therapeutics by Lei Zhang, Xichu Duan, Yanhua Zhao, Dejiu Zhang, Yuan Zhang

“…Indirectly, they may affect tumor metastasis by modulating the host immune system and the tumor microenvironment. These recent findings have reshaped our understanding of the relationship between microorganims and the metastatic process. …”
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Compliant immune response of silk-based biomaterials broadens application in wound treatment by Zhiqiang Tian, Hong Chen, Ping Zhao

“…However, different silk-processing methods may trigger intense immune system resistance after implantation into the body. …”
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Protocol for Immune Cell Isolation, Organoid Generation, and Co-culture Establishment from Cryopreserved Whole Human Intestine by Enrique Gamero-Estevez, Inga Hensel, Michelle Steinhauer, Olivia Müllertz, Elizaveta Savochkina, Ibrahim Sektioglu, Bilgenaz Stoll, Shaghayegh Derakhshani, Sarah Devriese, Kyungbo Kim, Martin Resnik-Docampo

“…The human intestine plays a pivotal role in nutrient absorption and immune system regulation. Along the longitudinal axis, cell-type composition changes to meet the varying functional requirements. …”
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Seaweed-derived bioactives: Gut microbiota targeted interventions for immune function by Holly Sedgwick, Glenn Gibson, Jessica Adams, Anisha Wijeyesekera

“…Alginate, laminarin, and in some cases fucoidan, have shown to modify the microbiota, its metabolites, and immune system function in in vitro research. Selected species of Bacteroides ferment these polysaccharides and have been shown to exert immunomodulatory effects in animal models. …”
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NF-κB Inhibitory Activity of the Di-Hydroxy Derivative of Piperlongumine (PL-18) by Yael Schlichter Kadosh, Subramani Muthuraman, Ariel Kushmaro, Rajendran Saravana Kumar, Jacob Gopas

“…Inflammation is a critical response of the immune system to infection or injury, serving to repair and restore tissue homeostasis. …”
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Profile of STING agonist and inhibitor research: a bibliometric analysis by Xuemei Wang, Qian Wang, Yidan Gao, Lijuan Jiang, Lingli Tang

“…BackgroundSTING is a core signaling hub molecule in the innate immune system, involved in various diseases, including infectious diseases, autoimmune diseases, tumors, aging, organ fibrosis, and neurodegenerative diseases. …”
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Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial by Ana Belén Fernández-Serrano, Francisco José Moya-Faz, Cesar Augusto Giner Alegría, Juan Carlos Fernández Rodríguez, Jose Francisco Soriano Guilabert, Martín del Toro Mellado

“…In addition, women are more likely to develop an anxiety and depression disorder, in comorbidity with a wide spectrum of diseases related to the immune system. In recent years, hydrogen-rich water has emerged as a promising therapeutic strategy to prevent and intervene in stress-related disorders, due to its antioxidant and anti-inflammatory properties. …”
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An Analysis of Macro Nutrition in Red Dragon Fruit (Hylocereus Polurhizus) Peel Dodol by Widyawaty, Ayu Lestari

“…It is suggested that the government should take some food diversification to increase people’s interest to consume nutritious food to increase immune system so that the community’s nutritional status can increase.…”
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PRRSV-2 nsp2 Ignites NLRP3 inflammasome through IKKβ-dependent dispersed trans-Golgi network translocation. by Lujie Zhang, Yanni Gao, Haoran Zhou, Xiao Liang, Xiaolin Jiang, Wenqin Gong, Yangyang Sun, Desheng Zhang, Xianwei Wang, Hans Nauwynck, Juan Bai, Ping Jiang

“…The NLRP3 inflammasome is a fundamental component of the innate immune system, yet its excessive activation is intricately associated with viral pathogenesis. …”
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Forward programming of hPSCs to neutrophils using chemically defined media by Hayley E. Hall, Xiaoping Bao, Cheng Dong, Xiaojun Lance Lian

“…Abstract Polymorphonuclear neutrophils (PMNs), the most abundant leukocytes circulating in human blood, are pivotal players in the innate immune system. In recent years, PMNs have gained increasing recognition for their significant involvement in the pathogenesis of a wide array of human diseases, including sepsis, pulmonary conditions, autoimmune disorders, and various cancers. …”
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DNA metabarcoding technology for the identification of the fecal microbiome in patients with chronic stress by Abraham Eudes Pérez Urruchi, Lucy Eliana Ramírez Elizalde, Flor de María Zapata Cornejo, María Luisa Matalinares Calvet, Miluska Vanessa Baylon Cuba, Fredy Fabian Dominguez

“…In the latest research, the concept of stress is associated with the deregulation of several biological systems sensitive to stress, such as the immune system, the microbiome, the endocrine system and neuroanatomical substrates. …”
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Increased Vitamin B12 Levels in Patients with Oral Cancer by Prashant Gupta, Subhash Chandra, Awanindra Kumar Jha, Tanya Khaitan, Anjani Kumar Shukla, Shantala R Naik

“…Serum vitamin B12 is important in maintaining the immune system and also repairing the damaged deoxyribonucleic acid (DNA) of cells. …”
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Fifty years after the discovery of the association of HLA B27 with ankylosing spondylitis by Joachim Sieper, Juergen Braun

“…The function of HLA class I molecules is to present peptides to the immune system to defend the organism against microbes targeted by CD8+T cells. …”
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South African Rheumatism and Arthritis Association 2024 guidelines for the use of biologic and targeted synthetic disease-modifying antirheumatic drugs by E van Duuren, J Potts, U Brijlal, S Botha, S Didi, K Makan, M van Dam, K Chinniah, B Hodkinson

“… Biologic and targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) target a specific pathway of the immune system, and are usually prescribed after failure of conventional synthetic disease-modifying antirheumatic drug therapy. …”
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