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541
A pressure model of immune response to mycobacteriumtuberculosis infection in several space dimensions
Published 2010-03-01“…However, in general, the human immune system is able to contain it. In this work, we propose a mathematical model which describes the early immune response to the Mtb infection in the lungs, also including the possible evolution of the infection in the formation of a granuloma. …”
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542
A fractal–fractional order modeling approach to understanding stem cell-chemotherapy combinations for cancer
Published 2025-01-01“…Also, the result of the numerical simulation and graphic for the concentration of cells over time indicate the effects of the therapies on the decay rate of tumor cells and the growth rate of effector cells to modify the cancer patient’s immune system. It is worth noting that we simulated all the model components with different fractional orders, confirming the effect of stem cell therapy and chemotherapy on the cells and the decay of cancer cells.…”
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543
The Immune Response and Its Therapeutic Modulation in Bronchiectasis
Published 2012-01-01“…Interestingly, a defect in the immune system or suppression of immune response during conditions such as immunodeficiency may well predispose one to the devastating effects of BC. …”
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544
Single-Cell Transcriptome Analysis Profile of Meniscal Tissue Macrophages in Human Osteoarthritis
Published 2020-01-01“…Unlike rheumatoid arthritis and other autoimmune diseases, inflammation in OA is chronic and, in relatively low grade, mainly mediated by the innate immune system, especially macrophages. However, due to its low abundance, there is a lack of systematic studies on macrophages in the OA condition. …”
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545
Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals
Published 2014-01-01“…Being critical in cancer control and progression, the immune system’s appropriate modulation may provide effective therapeutic options. …”
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546
Treatment of Acute Graft-versus-Host Disease in Liver Transplant Recipients
Published 2021-01-01“…Many different therapeutic measures have been utilized that target various immune system pathways, but steroids remain the first line of therapy. …”
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547
Neonatal Sepsis due to Coagulase-Negative Staphylococci
Published 2013-01-01“…Multiple factors, including prematurity, invasive life-saving medical interventions, and immaturity of the innate immune system, put these infants at greater risk of developing infection. …”
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548
A mathematical model for cellular immunology of tuberculosis
Published 2011-07-01“…The causative agent is Mycobacterium tuberculosis (Mtb), whose main target are the macrophages, important immune system cells. Macrophages and T cell populations are the main responsible for fighting the pathogen. …”
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549
Identification of the Immune Cell Infiltration Landscape in Head and Neck Squamous Cell Carcinoma (HNSC) for the Exploration of Immunotherapy and Prognosis
Published 2022-01-01“…However, infiltration of HNSCs by the immune system has not been determined to date. In this work, we proposed computational algorithms to identify different immune subtypes. …”
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550
Predictors associated with time to default for HIV/AIDS patients under HAART at Debre Tabor Referral Hospital: a Cox regression model
Published 2025-01-01“…Abstract The human immunodeficiency virus systematically undermines the immune system, which serves as our body’s inherent safeguard against diseases. …”
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551
Increased Vitamin B12 Levels in Patients with Oral Cancer
Published 2023-04-01“…Serum vitamin B12 is important in maintaining the immune system and also repairing the damaged deoxyribonucleic acid (DNA) of cells. …”
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552
Periorbital Necrotising Fasciitis after Minor Skin Trauma
Published 2014-01-01“…In this study, we represent periorbital necrotizing fasciitis case in a patient with normal immune system. The patient applied the emergency clinic with the complaints of swelling and redness on the left eye. …”
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553
Zygomycosis in Two Hematologic Cases
Published 2011-01-01“…Here we present two patients with hematologic diseases (one with leukemia, the second with aplastic anemia) with an impaired immune system and the diagnosis of zygomycosis. The survival of one of them was mainly due to early diagnosis and surgical debridement; unfortunately the second was misdiagnosed as an extensive ecchymosis due to thrombocytopenia and died with CNS involvement.…”
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554
Advances in Immunotherapy for Melanoma: A Comprehensive Review
Published 2017-01-01“…Cancer-specific active immunotherapy is an experimental form of treatment that stimulates the immune system to recognize antigens on the surface of cancer cells. …”
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555
Sigma Virus (DMelSV) Incidence in Lines of Drosophila melanogaster Selected for Survival following Infection with Bacillus cereus
Published 2017-01-01“…Given a finite energy budget, flies that have experienced immune system challenge may show alterations in other life history traits. …”
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556
Novel IL2RG gene mutation causing primary combined immunodeficiency disease: A case report and literature review
Published 2024-09-01“…Review of the case revealed that the child has had recurrent bronchitis, otitis media, skin allergies, and viral warts since early childhood, indicating persistent immune system abnormalities. Imaging studies, including pulmonary and sinus CT scans, show significant bronchiectasis accompanied by infections and sinusitis. …”
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557
Advanced Glycation End Products Play Adverse Proinflammatory Activities in Osteoporosis
Published 2014-01-01“…On the other hand, the gradual deterioration of the immune system during aging (defined as immunosenescence) is also characterized by the generation of a high level of oxidants and AGEs. …”
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558
Small fiber neuropathy: clinical presentation, diagnostic methods, possibly causes and treatment
Published 2020-03-01“…There is a plethora of possible SFN causes, such as metabolic, immune system mediated or neurotoxic factors, although in about 50% of cases, the precise etiology remains unknown. …”
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559
Macrophages, Inflammation, and Tumor Suppressors: ARF, a New Player in the Game
Published 2012-01-01“…The interaction between tumor progression and innate immune system has been well established in the last years. …”
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560
A case of acute brucellosis associated with HIV infection in Turkey
Published 2024-11-01“…Human immunodeficiency virus (HIV)-positive patients are vulnerable to co-infections and super-infections due to targeting the immune system. Because opportunistic infections are considered primarily, it is very difficult to detect co-infections, especially Brucella spp., in this patient group. …”
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