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1961
Methylation Marks of Blood Leukocytes of Native Hucul Mares Differentiated in Age
Published 2019-01-01“…Genes colocated with age-related differentially methylated regions (age DMRs) are the members of pathways involved in cellular signal transduction, immune response, neurogenesis, differentiation, development, and cancer progression. …”
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1962
Innate Immune Recognition of Mycobacterium tuberculosis
Published 2011-01-01“…Among the TLR family, TLR2, TLR4, and TLR9 and their adaptor molecule MyD88 play the most prominent roles in the initiation of the immune response against tuberculosis. In addition to TLRs, other PRRs such as NOD2, Dectin-1, Mannose receptor, and DC-SIGN are also involved in the recognition of M. tuberculosis. …”
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1963
Potential and development of cellular vesicle vaccines in cancer immunotherapy
Published 2025-01-01“…DEVs play a role in amplifying the immune response by acting as carriers for the dissemination of antigenic substances in dendritic cells. …”
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1964
Evaluation of Oxidative Stress and Mitophagy during Adipogenic Differentiation of Adipose-Derived Stem Cells Isolated from Equine Metabolic Syndrome (EMS) Horses
Published 2018-01-01“…Mesenchymal stem cells (MSCs) are frequently used in both human and veterinary medicine because their unique properties, such as modulating the immune response and differentiating into multiple lineages, make them a valuable tool in cell-based therapies. …”
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1965
Identification of a novel immunogenic cell death-related classifier to predict prognosis and optimize precision treatment in hepatocellular carcinoma
Published 2025-01-01“…However, the influence of ICD on tumor microenvironment (TME) formation and immune response in Hepatocellular carcinoma (HCC) remains largely unexplored. …”
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1966
Immunity in the Cervix: Interphase between Immune and Cervical Epithelial Cells
Published 2019-01-01“…The cytokines subsequently recruit subsets of immune cells appropriate to a particular immune context and response, such as dendritic cells (DCs), T, B, and natural killer (NK) cells. The immune response, as most biological processes in the female reproductive tract (FRT), is mainly regulated by estrogen and progesterone and their (immune cells) responses vary during different physiological phases of reproduction, such as menstrual cycle, pregnancy, and post menopause. …”
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1967
A Proinflammatory Effect of the β-Glucan from Pleurotus cornucopiae Mushroom on Macrophage Action
Published 2017-01-01“…Our results suggested that the PCPS could induce proinflammatory action in the immune response. In addition, the proinflammatory effect of the PCPS on THP-1 was enhanced by 5′-GMP-Na, while it was reduced by vitamin D2. …”
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1968
Immune Privilege and Eye-Derived T-Regulatory Cells
Published 2018-01-01“…The eye and immune system use strategies to maintain the ocular immune privilege by regulating the innate and adaptive immune response, which includes immunological ignorance, peripheral tolerance to eye-derived antigens, and intraocular immunosuppressive microenvironment. …”
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1969
Mechanisms of Action of Mesenchymal Stem Cells in Metabolic-Associated Fatty Liver Disease
Published 2023-01-01“…They can also reduce liver tissue injury and reverse the development of MAFLD by regulating immune response, antifibrotic activities, and lipid metabolism. …”
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1970
Activation of Macrophages by Oligomeric Proteins of Different Size and Origin
Published 2018-01-01“…Activation of macrophages is one of the key processes in generating the immune response against pathogens or misfolded/aggregated otherwise unharmful host’s proteins. …”
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1971
Sigma Virus (DMelSV) Incidence in Lines of Drosophila melanogaster Selected for Survival following Infection with Bacillus cereus
Published 2017-01-01“…The immune response of Drosophila melanogaster is complex and involves both specific and general responses to parasites. …”
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1972
The Role of PPARs in Placental Immunology: A Systematic Review of the Literature
Published 2013-01-01“…They are expressed in most human organs and their function extends from regulating metabolism, homeostasis, and carcinogenesis to immune response. In the recent years, PPARs have been identified in most reproductive tissues and in all lines of immune cells. …”
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1973
Mitochondria-Targeted Biomaterials-Regulating Macrophage Polarization Opens New Perspectives for Disease Treatment
Published 2025-02-01“…Zui Tian,* Xudong Wang,* Shuai Chen,* Zijian Guo, Jingkai Di, Chuan Xiang Department of Orthopedics, Second Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chuan Xiang, Department of Orthopedics, Second Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China, Email chuanxiang@sxmu.edu.cnAbstract: Macrophage immunotherapy is an emerging therapeutic approach designed for modulating the immune response to alleviate disease symptoms. The balance between pro-inflammatory and anti-inflammatory macrophages plays a pivotal role in the progression of inflammatory diseases. …”
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1974
Histopathological, Immunohistochemical and Biochemical Studies of Murine Hepatosplenic Tissues Affected by Chronic Toxoplasmosis
Published 2022-01-01“…Many molecules like caspase-3, CD3, and CD138 are implicated in the tissue immune response in a trial to alleviate hazardous toxoplasmosis impact. …”
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1975
The Effect of Anthelmintic Treatment on Coccidia Oocyst Shedding in a Wild Mammal Host with Intermittent Cestode Infection
Published 2014-01-01“…Also, the marmot’s response towards coccidia infection appears optimal only under no helminth infection when the host immune response towards coccidia would not be compromised, thereby pointing to the importance of regular intestinal helminth elimination by marmots just before hibernation.…”
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1976
Pathogenic Roles of Macrophage Migration Inhibitory Factor during Dengue Virus Infection
Published 2015-01-01“…MIF is a critical mediator of the host immune response and inflammation, and there is a correlation between the serum levels of MIF and disease severity in dengue patients. …”
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1977
Upregulation of FOXO3 in New-Onset Type 1 Diabetes Mellitus
Published 2020-01-01“…FOXO3 plays a crucial role in physiologic and pathologic immune response. FOXO3, cooperatively with FOXO1, control the development and function of Foxp3+ regulatory T cells (Treg). …”
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1978
Data Mining Mycobacterium tuberculosis Pathogenic Gene Transcription Factors and Their Regulatory Network Nodes
Published 2018-01-01“…It was predicted that IL-6, JUN, and TP53, along with transcription factors SRC, TNF, and MAPK14, could regulate the immune response, with their function being extracellular region activity and protein binding during infection with M. tuberculosis.…”
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1979
Structure simulation-based comparison of active site variations in fungal ornithine decarboxylases
Published 2025-12-01“…Polyamines play crucial roles in various biological processes, including cell proliferation and differentiation, immune response modulation, and signal transduction. Ornithine decarboxylase (ODC) initiates polyamine biosynthesis by catalyzing the conversion of ornithine to putrescine in a pyridoxal phosphate (PLP)-dependent manner. …”
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1980
3-(5-Hydroxyphenyl)-5-Phenyl-2-Pyrazolines as Toll-Like Receptor 7 Agonists
Published 2023-01-01“…These data suggest that compound 6 induces an innate immune response by agonizing TLR7 activity in THP1 human monocytic cells. …”
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