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1921
Effectiveness and Safety of Dupilumab and Tralokinumab for Treating Atopic Dermatitis and Pruritic Skin Disorders in Oncological Patients: A Narrative Review
Published 2025-01-01“…In recent years, biologic agents such as dupilumab and tralokinumab have emerged as promising treatments for AD, offering targeted modulation of the immune response with potentially fewer systemic side effects. …”
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1922
Effect of preoperative immunonutrition on complications after salvage surgery in head and neck cancer
Published 2019-05-01“…By improving both tissue regeneration and immune response, immunonutrition may help to improve surgical outcomes in this high-risk population.…”
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1923
Results of experimental infection of vaccinated and non-vaccinated ducklings with duck hepatitis virus
Published 2022-12-01“…It has been shown that in case of immunization of 3-day-old ducklings, the experimental vaccine induces antibody-mediated immune response, no harmful effect is produced on poultry if a tenfold dose is administered which indicates its safety, and the vaccine ensures protection against infection with a control virulent strain of hepatitis virus.…”
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1924
Plant cell wall and the mechanisms of resistance to pathogens
Published 2016-01-01“…In total, the plan cell wall is a complex dynamic structure able to prevent infection by most potential (non-specific) pathogens and switch on the mechanisms of plant immune response. The reconstruction of gene networks controlling the cell wall structural and functional organization during the growth, and under normal and stressful conditions is vitally important for understanding the basic molecular mechanisms of development and stress resistance. …”
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1925
Intersection between individual, household, environmental and system level factors in defining risk and resilience for children in Kenya's ASAL: A qualitative study.
Published 2025-01-01“…Nonetheless, sources of resilience include breastfeeding, immunization, responsive caregiving, family and community support, higher socio-economic status (SES), cultural practices, self-motivation, hard work, community role models, religious activities and quality service provision.…”
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1926
Synergic Renoprotective Effects of Combined ASC Therapy with RAAS Blockade in Experimental Advanced CKD
Published 2022-01-01“…The beneficial effects of ACS are possibly due to the immunomodulatory and anti-inflammatory role of factors secreted by these cells, modulating the local immune response. Although studies are still required, our results demonstrated that a subcapsular inoculation of ASC, associated with the administration of Losartan, exerted additional renoprotective effect in rats submitted to a severe model of established CKD, when compared to Losartan monotherapy, thus suggesting ASC may be a potential adjuvant to RAAS-blockade therapy currently employed in the conservative management of CKD.…”
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1927
MOSQUITO-BORNE PARASITES IN PATIENTS NEWLY INFECTED WITH HIV IN RELATIONSHIP WITH CD4 COUNT AND TNF ΑLPHA
Published 2021-07-01“…Background: Mosquito-borne parasites include the pathogenic protozoa and helminths that are transmitted by the insect vector which may co-infect with other organisms to elicit an immune response. Purpose: To determine the frequency of mosquito-borne parasites in patients newly infected with HIV in relationship with CD4 count and TNFα. …”
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1928
Crucial Genes in Aortic Dissection Identified by Weighted Gene Coexpression Network Analysis
Published 2022-01-01“…DEGs were rich in certain categories such as MHC class II receptor activity, MHC class II protein complex, and immune response genes. Gene coexpression networks via WGCNA identified 3 gene hub modules, with one positively and 2 negatively correlated with AD, respectively. …”
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1929
LAMB1 promotes proliferation and metastasis in nasopharyngeal carcinoma and shapes the immune-suppressive tumor microenvironment
Published 2025-03-01“…But at low level of fibroblasts, LAMB1 directly suppressed immune response. Tumors with high LAMB1 level had weak responses to immunotherapy. …”
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1930
Co-dynamics of hepatitis B and C viruses under the influence of CTL immunity
Published 2025-04-01“…Understanding the cytotoxic T lymphocyte (CTL) immune response against hepatitis B virus (HBV) and hepatitis C virus (HCV) infections is crucial, as these infections can lead to liver cirrhosis and cancer. …”
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1931
Timosin alpha-1 immunomodulating properties
Published 2009-02-01“…Immunomodulating effect of Timosin alpha-1 consists in increase of natural killer cells number, CD4 and CD8 by stimulation of stem cells differentiation and decrease of T-cells apoptosis, and also in driving of immune response to Th1 subtype by increase of Th1 cytokines (IL-2, IFN) amount and decreases of amount of Th2 cytokines (IL-4, IL-10). …”
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1932
Weighted Gene Coexpression Network Analysis Identifies TBC1D10C as a New Prognostic Biomarker for Breast Cancer
Published 2022-01-01“…The tumor microenvironment (TME) can downregulate the immune response to cancer therapy. Our study is aimed at finding a TME-related biomarker to identify patients who might respond to immunotherapy. …”
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1933
RETRACTED ARTICLE: Impact TB co-infections on immune tolerance among people living with HIV: a systematic review
Published 2023-12-01“…J. (2012). HIV-1 and the Immune Response to TB. Future Virology, 8(1), 57–80. https://doi.org/10.2217/fvl.12.123 Upon query, the author has not been able to provide a satisfactory explanation for this significant level of overlap. …”
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1934
The Value of Immune-Related Genes Signature in Osteosarcoma Based on Weighted Gene Co-expression Network Analysis
Published 2021-01-01“…The differential genes in the high- and low-risk groups were analyzed by enrichment analysis of GO and KEGG, indicating that the EVI2B model is associated with immune response. Conclusion. In this study, IRG EVI2B is closely related to OS’s prognosis and can be used as a potential biomarker for prognosis and treatment of OS.…”
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1935
Activation of FGD5-AS1 Promotes Progression of Cervical Cancer through Regulating BST2 to Inhibit Macrophage M1 Polarization
Published 2021-01-01“…Bone marrow stromal cell antigen 2 (BST2) can play critical roles in immune response, and the roles of BST2 in cervical cancer was explored currently. …”
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1936
Role of Cholinergic Anti-Inflammatory Pathway in Protecting Sepsis-Induced Acute Lung Injury through Regulation of the Conventional Dendritic Cells
Published 2022-01-01“…The cholinergic anti-inflammatory pathway connects the immune response system and the nervous system via the vagus nerve. …”
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1937
Design of a humanized CD40 agonist antibody with specific properties using AlphaFold2 and development of an anti-PD-L1/CD40 bispecific antibody for cancer immunotherapy
Published 2025-02-01“…Challenges in immunotherapy include inefficient early events in the immune response cycle, such as antigen presentation and T cell priming. …”
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1938
Recombinant short TNF-BD protein from smallpox virus is pharmacologically active in an experimental septic shock model
Published 2020-05-01“…These proteins compete with cellular receptors for cytokine binding, thus blocking the antiviral immune response. In particular, the G2R gene of VARV encodes the TNF decoy receptor, VARV-CrmB protein. …”
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1939
Review: Feed efficiency and metabolic flexibility in livestock
Published 2025-01-01“…Metabolic flexibility for adaptation to disease, and response to regular stress implies that a more reactive immune response and reduced fear response results in higher feed efficiency. …”
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1940
Prediction of Immune Infiltration Diagnostic Gene Biomarkers in Kawasaki Disease
Published 2022-01-01“…Kawasaki disease (KD) is characterized by disorder of immune response with unknown etiology. Immune cells may be closely related to the onset of KD. …”
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