Inborn errors of immunity (primary immunodeficiencies) by Vy H. D. Kim, Julia E. M. Upton, Beata Derfalvi, Kyla J. Hildebrand, Christine McCusker

“…The treatment of IEIs is complex and generally requires both supportive and definitive strategies, including but not limited to, immunoglobulin replacement therapy, antibiotic prophylaxis, immune response modifiers, and hematopoietic stem cell transplantation. …”
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Endogenous nitroso compounds (NOC) from dietary source: Plausible promoters of oral carcinogenesis in non-smokers and non-alcoholics by Rajashree Padmanaban, Ramya Ramadoss, Rajkumar Krishnan

“…Discussion: The intricate interplay between endogenous nitroso compounds, oral microbiota, and the host's immune response presents a complex landscape in understanding the promotion of oral carcinogenesis in non-smokers and non-alcoholics. …”
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Systematic dissection of pleiotropic loci and critical regulons in excitatory neurons and microglia relevant to neuropsychiatric and ocular diseases by Yunlong Ma, Dingping Jiang, Jingjing Li, Gongwei Zheng, Yao Deng, Xuanxuan Gou, Shuaishuai Gao, Cheng Chen, Yijun Zhou, Yaru Zhang, Chunyu Deng, Yinghao Yao, Haijun Han, Jianzhong Su

“…Functionally, excitatory neuron-specific regulons were involved in axon guidance and synaptic activity, while microglia-specific regulons were associated with immune response and cell activation. In sum, these findings underscore the genetic link between psychiatric disorders and ocular diseases.…”
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Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on Modeling of Published Data by Ga Hee Shin, Byeong-Chul Kang, Dai Ja Jang

“…The various unique microorganisms and bioactive components in kimchi show antioxidant activity and have been associated with an enhanced immune response, as well as anti-cancer and anti-diabetic effects. …”
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Macrophages in Tumor Microenvironments and the Progression of Tumors by Ning-Bo Hao, Mu-Han Lü, Ya-Han Fan, Ya-Ling Cao, Zhi-Ren Zhang, Shi-Ming Yang

“…Macrophages are widely distributed innate immune cells that play indispensable roles in the innate and adaptive immune response to pathogens and in-tissue homeostasis. …”
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A bibliometric and visualized analysis of heartland virus by Huiying Zhang, Huiying Zhang, Leiliang Zhang, Leiliang Zhang

“…Currently, researchers are focusing on pathogenesis, immune response, vector relationships, and epidemiology, providing valuable insights for future studies.…”
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Role of Lactate in Inflammatory Processes: Friend or Foe by Carolina Manosalva, John Quiroga, John Quiroga, Alejandra I. Hidalgo, Pablo Alarcón, Nicolás Ansoleaga, Nicolás Ansoleaga, María Angélica Hidalgo, Rafael Agustín Burgos

“…Additionally, various targets, including post-translational modifications, G-protein coupled receptor and transcription factor activation such as NF-κB and HIF-1, allow lactate to modulate signaling pathways that control the expression of cytokines, chemokines, adhesion molecules, and several enzymes associated with immune response and metabolism. Altogether, this would explain its varied effects on inflammatory processes beyond its well-known role as a waste product of metabolism.…”
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Evolutionary conserved regulation of TFEB stability by the E3 ubiquitin ligase WWP2 modulates response to stress in vivo by Juan A. Garcia-Sanchez, Estelle Bonnet, Céline Loubatier, Anne Doye, Guillaume Paillier, Fabien Segui, Frédéric Larbret, Paul Chaintreuil, Ludovic Batistic, Cédric Torre, Marcel Deckert, Jolanta Polanowska, Patrick Munro, Laurent Boyer, Orane Visvikis

“…We identified WWP-1 as a regulator of HLH-30-dependent immune response controlling HLH-30 stability to mediate host defense in vivo. …”
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Sarcoid-Like Mediastinal Lymphadenopathy in Gynecologic Malignancy by Bilal H. Lashari, Megumi Asai, Gissele Randleman, Martha Sack, Rajeshkumar Patel

“…Noncaseating granulomas are seen surrounding tumors with varying frequency, possibly as part of an immune response to tumor cells. However, data about the association of sarcoid with gynecologic malignancy is sparse. …”
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EFFECT OF p30 RECOMBINANT PROTEIN ON AFRICAN SWINE FEVER VIRUS IN VITRO REPRODUCTION by Ali Mazloum, I. Yu. Zhukov, A. S. Pershin, A. S. Igolkin, N. N. Vlasova

“…However, it is necessary to study the function of definite viral proteins, their role in immune response morphogenesis and induction to determine the components to be included into ASF protection drugs. …”
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Potential of Eurycoma longifolia, Curcuma zedoaria, and Allium sativum extracts as phytobiotics for shrimp health by Mohamad Iqbal Kurniawinata, Sukenda Sukenda, Dinamella Wahjuningrum, Widanarni Widanarni, Julie Ekasari

“… This study evaluated the efficacy of Eurycoma longifolia, Curcuma zedoaria, and Allium sativum in improving the immune response and resistance of whiteleg shrimp to prevent Vibrio parahaemolyticus infection. …”
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Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3 by Ling Ye, Shengqi Shen, Qiankun Mao, Hui Lu, Haiying Liu, Pinggen Zhang, Zetan Jiang, Wenhao Ma, Yuchen Sun, Yiyang Chu, Zilong Zhou, Rui Liu, Jian Li, Shi-ting Li, Ping Gao, Huafeng Zhang

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A randomized, placebo-controlled trial of the BTK inhibitor zanubrutinib in hospitalized patients with COVID-19 respiratory distress: immune biomarker and clinical findings by Steven P. Treon, Camille N. Kotton, David J. Park, Giorgia Moranzoni, Camilla K. Lemvigh, Joseph C. Gathe, Tilly A. Varughese, Christopher F. Barnett, Johnny M. Belenchia, Nina M. Clark, Charles M. Farber, Muhammad Bilal Abid, Gulrayz Ahmed, Christopher J. Patterson, Maria L. Guerrera, Jacob D. Soumerai, Vipheaviny A. Chea, Isabel P. Carulli, Jackson Southard, Shuqiang Li, Catherine J. Wu, Kenneth J. Livak, Eric Holmgren, Pil Kim, Carrie Shi, Holly Lin, Vanitha Ramakrishnan, Ying Ou, Scott Olszewski, Lars Rønn Olsen, Derin B. Keskin, Derin B. Keskin, Zachary R. Hunter, Christopher Tankersley, Todd Zimmerman, Binod Dhakal

“…BackgroundCytokine release triggered by a hyperactive immune response is thought to contribute to severe acute respiratory syndrome coronavirus 2019 (SARS-CoV-2)–related respiratory failure. …”
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Use of Autoantibodies to Detect the Onset of Breast Cancer by Jérôme Lacombe, Alain Mangé, Jérôme Solassol

“…Identification of tumor-specific markers capable of eliciting an immune response in the early stages of tumor development seems to provide an effective approach for early diagnosis. …”
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Combination Immunosuppressive Therapy in Primary Autoimmune Inner Ear Disease in Pregnancy by Saikrishna Ananthapadmanabhan, Joe Jabbour, David Brown, Vanaja Sivapathasingam

“…Suppression or modulation of the immune response can minimize cochleitis allowing for potential recovery of hearing. …”
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CXCR2 in Acute Lung Injury by F. M. Konrad, J. Reutershan

“…In pulmonary inflammation, recruitment of circulating polymorphonuclear leukocytes is essential for host defense and initiates the following specific immune response. One pathological hallmark of acute lung injury and acute respiratory distress syndrome is the uncontrolled transmigration of neutrophils into the lung interstitium and alveolar space. …”
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Novel anti-inflammatory properties of mannose oligosaccharides in the treatment of inflammatory bowel disease via LGALS3 modulation by Yaqi Du, Yan Fan, Xin Li, Fenqin Chen

“…Detailed molecular analyses further demonstrated that these changes in microbiota were associated with modifications in the host’s immune response, particularly through the suppression of key inflammatory pathways and cytokines involved in IBD progression. …”
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Antibody dynamics in dogs submitted to different canine visceral leishmaniasis treatment protocols by Eliesse Pereira Costa, Gisele Vaz Aguirre Samoel, Gilneia da Rosa, Vanessa Osmari, Michelli Lopes de Souza, Luís Felipe Dias Lopes, Fernanda Silveira Flôres Vogel, Sônia de Avila Botton, Luís Antônio Sangioni

“…Furthermore, the immune response of animals must be considered, given the challenges of parasitic loads in infections. …”
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Evaluation of Nutritional Supplements on Periodontal Fibroblast in Systemic Disease Conditions: An In Vitro Study by Saleh A. Alsanie

“…Specifically, vitamin C and omega-3 fatty acids demonstrated significant protective effects against inflammation-induced cell damage, while probiotics promoted a balanced immune response. Conclusion: Nutritional supplements, including vitamin C, vitamin D, omega-3 fatty acids, and probiotics, exhibit promising effects on periodontal health in systemic disease conditions. …”
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The Role of Type III Interferons in Hepatitis C Virus Infection and Therapy by Janina Bruening, Bettina Weigel, Gisa Gerold

“…Among the three classes of IFNs, type III IFNs, also called IFN lambdas (IFNLs), are an essential component of the innate immune response to hepatitis C virus (HCV). In particular, human polymorphisms in IFNL gene loci correlate with hepatitis C disease progression and with treatment response. …”
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