Association Between Single-Nucleotide Polymorphisms in <i>Toll-like Receptor 3</i> (<i>tlr3</i>), <i>tlr7</i>, <i>tlr8</i> and <i>tirap</i> Genes with Severe Symptoms in Children P... by Adriana Souza Andrade, Aline Almeida Bentes, Lilian Martins Diniz, Silvia Hees Carvalho, Erna Geessien Kroon, Marco Antonio Campos

“…Studies indicate that comorbidities and genetic factors, such as polymorphisms in immune response genes, can influence the severity of COVID-19. …”
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Chronic Rhinosinusitis without Nasal Polyps in Asian Patients Shows Mixed Inflammatory Patterns and Neutrophil-Related Disease Severity by Dae Woo Kim, Kyoung Mi Eun, Eun Youn Roh, Sue Shin, Dong-Kyu Kim

“…Western studies revealed that CRS without nasal polyps (CRSsNP) showed a predominantly type 1 immune response and CRS with nasal polyps (CRSwNP) was characterized by type 2 immune response; however, the detailed immunologic profile of CRSsNP in Asian patients has not been thoroughly investigated. …”
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Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils by E. Jablonska, M. Marcinczyk

“…Background: Available data indicate that neutrophils (PMN) produce a wide range of cytokines with the potential to modulate immune response. Recent investigation have shown that interleukin (IL)-15 and IL-18 potentiated several functions of normal neutrophils. …”
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Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation by Nguyen P. Tran, Jeremy Katcher, Erin Rohman, Mary Francis Hall, Christie F. Michael, Isao Miyairi, D. Betty Lew

“…Lymphocyte blast transformation (LBT), a method of detecting cellular immune response by measuring levels of interferon-γ (IFN-γ), was used to diagnose vancomycin hypersensitivity and guide antibiotic selection.…”
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Cell fusion as a driver of metastasis: re-evaluating an old hypothesis in the age of cancer heterogeneity by Eduardo López-Collazo, Eduardo López-Collazo, Eduardo López-Collazo, Eduardo López-Collazo, Laura Hurtado-Navarro, Laura Hurtado-Navarro

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Cellular Immunogenicity of Novel Gene Immunogens in Mice Monitored by in Vivo Imaging by Elizaveta Starodubova, Olga Krotova, David Hallengärd, Yulia Kuzmenko, Gunnel Engström, Diana Legzdina, Oleg Latyshev, Olesja Eliseeva, Anna Karin Maltais, Vera Tunitskaya, Vadim Karpov, Andreas Bråve, Maria Isaguliants

“…The efficient cell-mediated immune response clears cells expressing deoxyribonucleic acid (DNA) immunogens, but there are no methods to monitor this in vivo. …”
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Molecular Targets of Shenqi Dihuang, A Traditional Chinese Herbal Medicine, and Its Potential Role in Renal Cell Carcinoma Therapy by Xinglin Chen, Tongtong Zhang, Xiangyang Zhan, Xinyue Zang, Xinyu Zhai, Zhong Wan, Minyao Ge, Mingyue Tan, Jianyi Gu, Dongliang Xu

“…Finally, the pathways enrichment analysis revealed that response to oxidative stress, cyclin binding, programmed cell death, and immune response are the most enriched pathways in CCND1. …”
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Equivariant Hopf Bifurcation in a Time-Delayed Ring of Antigenic Variants by Israel Ncube

“…We consider an intrahost malaria model allowing for antigenic variation within a single species. The host’s immune response is compartmentalised into reactions to major and minor epitopes. …”
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Liver HLA-E Expression Is Associated with Severity of Liver Disease in Chronic Hepatitis C by Roberta C. Araújo, Fabricio C. Dias, Bruna C. Bertol, Deisy M. Silva, Patrícia H. Almeida, Andreza C. Teixeira, Fernanda F. Souza, Marcia G. Villanova, Leandra N. Z. Ramalho, Eduardo A. Donadi, Ana L. C. Martinelli

“…Hepatitis C virus (HCV) can escape from innate and adaptive immunity, making the immune response ineffective. Human leukocyte antigen E (HLA-E) might regulate the antiviral function of immune response and contribute to the persistence of HCV and the severity of liver disease. …”
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A SH3b domain-containing peptidoglycan recognition protein from Magallana gigas with broad recognition spectrum by Yinan Li, Hongbo Lu, Chuanyan Yang, Zhuyun Liu, Weilin Wang, Chang Liu, Lingling Wang

“…Peptidoglycan recognition protein (PGRP) is a kind of conserved pattern recognition receptors (PRRs) and plays important roles in innate immune response in both invertebrates and vertebrates. …”
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Reduced Serum Butyrylcholinesterase Activity Indicates Severe Systemic Inflammation in Critically Ill Patients by Aleksandar R. Zivkovic, Karsten Schmidt, Annette Sigl, Sebastian O. Decker, Thorsten Brenner, Stefan Hofer

“…Systemic inflammation is an immune response to a nonspecific insult of either infectious or noninfectious origin and remains a challenge in the intensive care units with high mortality rate. …”
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Ethanol-Induced Alterations of T Cells and Cytokines after Surgery in a Murine Infection Model by Nadine Lanzke, Mario Menk, Clarissa von Haefen, Lilit Sargsyan, Bianca Scharf, Klaus-Dieter Wernecke, Claudia D. Spies

“…These effects may contribute to an impaired immune response after surgery.…”
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Effect of Dietary Combination of Methionine and Fish Oil on Cellular Immunity and Plasma Fatty Acids in Infectious Bursal Disease Challenged Chickens by Elham Maroufyan, Azhar Kasim, Goh Yong Meng, Mahdi Ebrahimi, Loh Teck Chwen, Parvaneh Mehrbod, Behnam Kamalidehghan, Abdoreza Soleimani Farjam

“…This study was carried out to investigate the modulatory effects of dietary methionine and fish oil on immune response, plasma fatty acid profile, and blood parameters of infectious bursal disease (IBD) challenged broiler chickens. …”
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An antibody cocktail targeting two different CD73 epitopes enhances enzyme inhibition and tumor control by Jin-Gen Xu, Shi Chen, Yang He, Xi Zhu, Yanting Wang, Zhifeng Ye, Jin Chuan Zhou, Xuanhui Wu, Lei Zhang, Xiaochen Ren, Huifeng Jia, Haijia Yu, Xiaoyue Wei, Yujie Feng, Xiaofang Chen, Xiaopei Cui, Xianfei Pan, Shaojie Wang, Simin Xia, Hongjie Shang, Yueqing Pu, Wei Xu, Haidong Li, Qian Chen, Zeyu Chen, Manfu Wang, Xiaodong Yan, Hui Shi, Mingwei Li, Yisui Xia, Roberto Bellelli, Shunli Dong, Jun He, Jun Huang, Chen-Leng Cai, Xiangyang Zhu, Yifan Zhan, Li Wan

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Regulatory T Cells: Molecular Actions on Effector Cells in Immune Regulation by Asiel Arce-Sillas, Diana Denisse Álvarez-Luquín, Beatriz Tamaya-Domínguez, Sandra Gomez-Fuentes, Abel Trejo-García, Marlene Melo-Salas, Graciela Cárdenas, Juan Rodríguez-Ramírez, Laura Adalid-Peralta

“…T regulatory cells play a key role in the control of the immune response, both in health and during illness. While the mechanisms through which T regulatory cells exert their function have been extensively described, their molecular effects on effector cells have received little attention. …”
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Cellular and cytokine immunoregulation in patients with chronic obstructive pulmonary disease and bronchial asthma by Wanda Stankiewicz, Marek P. Dabrowski, Andrzej Chcialowski, Tadeusz Plusa

“…In addition to diverse effector mechanisms, the cellular and humoral elements participating in the development of immune response may appear to be different in COPD and bronchial asthma (BA) patients.…”
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Identification and Characterization of a Novel Rat MAVS Variant Modulating NFκB Signaling by Ihsan Nalkiran, Hatice Sevim Nalkiran

“…The innate immune response serves as the primary defense against viral infections, with the recognition of viral nucleic acids by pattern recognition receptors (PRRs) initiating antiviral responses. …”
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The Role of Immune Defense in Serratia marcescens Nosocomial Infections by Ihsan A. Raheem, Fatima R. Abdul, Hanan T. Subhi

“…Serratia marcescens are well known to be opportunistic and are equipped with an armory of virulence factors against host immune response. The study aims to detect the immune defense in patients infected with multidrug-resistant S. marcescens. …”
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Proteomic Profiling and Functional Analysis of B Cell-Derived Exosomes upon Pneumocystis Infection by Dan Ma, Qian-Yu Zhang, Heng-Mo Rong, Kan Zhai, Zhao-Hui Tong

“…They were mainly associated with immune response and transcription regulation. PRM analysis confirmed the significantly changed levels of histone H1.3, vimentin, and tyrosine-protein phosphatase nonreceptor type 6 (PTPN6). …”
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PET Study of Sphingosine-1-phosphate Receptor 1 Expression in Response to S. aureus Infection by Hao Jiang, Jiwei Gu, Haiyang Zhao, Sumit Joshi, Joel S. Perlmutter, Robert J. Gropler, Robyn S. Klein, Tammie L. S. Benzinger, Zhude Tu

“…PET with S1PR1-specific radiotracer [18F]TZ4877 could provide a noninvasive tool for detecting the early S1PR1 immune response to infectious diseases.…”
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