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Can malaria parasite pathogenesis be prevented by treatment with tumor necrosis factor-alpha?
Published 2013-03-01Subjects: Get full text
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Spinal cord injury enhances lung inflammation and exacerbates immune response following exposure to LPS
Published 2025-01-01“…DiscussionsThis study demonstrated an increase in lung inflammation and immune responses subsequent to low-level T9 SCI, underscoring the widespread influence of systemic inflammation post-SCI, especially pronounced in specific organs like the lungs. …”
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Possible Implication of Local Immune Response in Darier's Disease: An Immunohistochemical Characterization of Lesional Inflammatory Infiltrate
Published 2010-01-01“…We hypothesize that the genetic damage of keratinocytes might result in a loss of some subsets of dendritic cells and, consequently, in an impaired local immune response, which might worsen the infections that inevitably occur in this disease.…”
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PMA1-containing extracellular vesicles of Candida albicans triggers immune responses and colitis progression
Published 2025-12-01“…Candida albicans (C. albicans) exhibits aberrant changes in patients with colitis, and it has been reported to dominate the colonic mucosal immune response. Here, we found that PMA1 expression was significantly increased in C. albicans from patients with IBD compared to that in healthy controls. …”
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Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications
Published 2022-01-01Get full text
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Efficacy of Rg1-Oil Adjuvant on Inducing Immune Responses against Bordetella bronchiseptica in Rabbits
Published 2021-01-01Get full text
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Bifurcation analysis of HIV-1 infection model with cell-to-cell transmission and immune response delay
Published 2015-11-01“…A within-host viral infection model with both virus-to-cell and cell-to-cell transmissions and time delay in immune response is investigated. Mathematical analysis shows that delay may destabilize the infected steady state and lead to Hopf bifurcation. …”
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Persistence of the Immune Response to an Intramuscular Bivalent (GI.1/GII.4) Norovirus Vaccine in Adults
Published 2025-01-01“…Methods: In this study, 428 adult recipients of various compositions of the norovirus vaccine candidate, HIL-214, were followed for 5 years, to assess immune responses to its virus-like particle antigens, GI.1 and GII.4c. …”
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In situ immune response in human chromoblastomycosis--a possible role for regulatory and Th17 T cells.
Published 2014-09-01“…The humoral immune response also seems to play a role. We intended to explore the populations of regulatory T cells and the Th17 pattern.…”
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Hopf bifurcation in a delayed model for tumor-immune system competition with negative immune response
Published 2006-01-01“…The dynamics of the model for tumor-immune system competition with negative immune response and with one delay investigated. We show that the asymptotic behavior depends crucially on the time delay parameter. …”
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Mesenchymal Stromal Cells Mediate Clinically Unpromising but Favourable Immune Responses in Kidney Transplant Patients
Published 2022-01-01“…No such favourable immune responses were observed in all MSC-infused patients. …”
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High-Grade Cervical Intraepithelial Neoplasia: Impact of Colposcopic Lesion Area on Systemic Immune Responses
Published 2025-02-01“…Getúlio Guaritá, s/n, Bairro Abadia, Uberaba, MG, 38025-440, Brazil, Tel +55 34 3318 5326, Fax +55 34 3318 5342, Email rosekeila@terra.com.brBackground: The progression of high-grade cervical intraepithelial neoplasia (CIN) and cervical cancer is accompanied by a reduction in the immune response. The objectives of the study were to determine whether colposcopic lesion area is associated with serum levels of cytokines IL (interleukin) − 1, IL-6, IL-8, IL-10, IL-12 and TNF-α in precursor lesions of cervical cancer.Methods: The study population comprised patients with high-grade squamous intraepithelial lesion who had undergone colposcopy, cervical biopsy, and measurements of serum cytokines by ELISA (Enzyme-Linked Immunosorbent Assay). …”
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A Controversial Role for IL-12 in Immune Response and Bone Resorption at Apical Periodontal Sites
Published 2010-01-01Get full text
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Exploring Immune Responses through Dynamic Modeling of Cell-Immune Interactions in Viral Infection and Vaccination
Published 2024-01-01“…This study examines the dynamics of viral infections and immune responses, with a particular focus on the roles of antibodies and CD8+ T cells induced by vaccination. …”
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mTORC1-Activated Monocytes Increase Tregs and Inhibit the Immune Response to Bacterial Infections
Published 2016-01-01“…The TSC1/2 heterodimer, a key upstream regulator of the mTOR, can inhibit the activation of mTOR, which plays a critical role in immune responses after bacterial infections. Monocytes are an innate immune cell type that have been shown to be involved in bacteremia. …”
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Immune responses in rodent whole eye transplantation: elucidation and preliminary investigations into rejection diagnosis and monitoring
Published 2025-01-01“…This study delves into the timeline and nature of immune responses in a rodent model of WET without immunosuppression, aiming to elucidate a detailed picture of the immune landscape post-transplantation and establish innovative diagnostic and monitoring methods.MethodsWe employed a multi-faceted approach to analyze immune responses post-WET, including assessments of gross changes in corneal transparency, thickness, and skin condition. …”
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RIF1 integrates DNA repair and transcriptional requirements during the establishment of humoral immune responses
Published 2025-01-01“…Abstract The establishment of protective immune responses relies on the ability of terminally differentiated B cells to secrete a broad variety of antigen-specific antibodies with different effector functions. …”
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