Bacterial carrier-mediated drug delivery systems: a promising strategy in cancer therapy by Sizuo Yan, Yu Gan, Huizhe Xu, Huizhe Xu, Haozhe Piao, Haozhe Piao

“…Bacteria have chemotaxis that can target and colonize tumor tissue, as well as activate anti-tumor immune responses, which makes them ideal for biomedical applications. …”
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Platelet microparticles level in juvenile idiopathic arthritis: A pediatric population-based cross-sectional study in a tertiary care center by Naresh Kumar, K Anu Punnen, Sukesh Chandran Nair, Visalakshi Jayaseelan, T Sathish Kumar

“…Background: Platelet-derived microparticles (PMPs) are small vesicles that are released from the plasma membrane upon platelet activation, which are then involved in haemostasis, vascular health, and have recently been shown to be intimately involved in immune responses. Aims and Objectives: We aimed to evaluate the level of plasma Platelet-derived micro particles in children with JIA and to assess the relationship between PMP levels and disease activity in JIA. …”
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Claudin-11 regulates immunological barrier formation and spermatogonial proliferation through stem cell factor by Taichi Sugawara, Kayoko Sonoda, Nattapran Chompusri, Kazuhiro Noguchi, Seiji Okada, Mikio Furuse, Tomohiko Wakayama

“…This suggests that adaptive immune responses to spermatogenic cells are not a cause of defective spermatogenesis in Cldn11-deficient mice. …”
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Effect of amniotic fluid on hair follicle growth by Gamze Tumentemur, Elif Ganime Aygun, Bulut Yurtsever, Didem Cakirsoy, Ercument Ovali

“…Both irradiated (FAFI) and non-irradiated (FAF) hAF were assessed for their efficacy and safety in promoting hair growth and modulating immune responses in a rat model of hair loss. The study examined HF regeneration, transition to the anagen phase, and macrophage polarization from the pro-inflammatory M1 phenotype to the anti-inflammatory M2 phenotype.Results: Both FAF and FAFI treatments significantly increased HF density, with FAFI exhibiting enhanced effects. …”
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Centrality of Hygienic Honey Bee Workers in Colony Social Networks by Adrian Perez, Brian R. Johnson

“…This work highlights the importance of considering the benefits of remaining socially integrated in important information networks and the temporal limitations for how quickly organized immune responses can occur in response to potential infections.…”
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Holding the Inflammatory System in Check: TLRs and Their Targeted Therapy in Asthma by Zhiyong Dong, Lingxin Xiong, Weijie Zhang, Peter G. Gibson, Ting Wang, Yanjiao Lu, Guoqiang Wang, Hui Li, Fang Wang

“…TLRs are the primary proteins associated with the innate and adaptive immune responses to these fatal factors and play an important role in recognizing pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), which initiates the downstream immune response. …”
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Parasite-derived plasma microparticles contribute significantly to malaria infection-induced inflammation through potent macrophage stimulation. by Kevin N Couper, Tom Barnes, Julius C R Hafalla, Valery Combes, Bernhard Ryffel, Thomas Secher, Georges E Grau, Eleanor M Riley, J Brian de Souza

“…This study therefore establishes parasitized red blood cell-derived MPs as a major inducer of systemic inflammation during malaria infection, raising important questions about their role in severe disease and in the generation of adaptive immune responses.…”
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The role of genetic diversity, epigenetic regulation, and sex-based differences in HIV cure research: a comprehensive review by Punitha Letchumanan, Kumitaa Theva Das

“…Sex-specific factors were also shown to play an important role with females, showing stronger early immune responses and higher representation among elite controllers. …”
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Antigen-Induced Immunomodulation in the Pathogenesis of Atherosclerosis by Natalia Milioti, Alexandra Bermudez-Fajardo, Manuel L. Penichet, Ernesto Oviedo-Orta

“…The present review summarises the most important scientific findings published within the last two decades on the importance of antigens, antigen stimulation, and adaptive immune responses in the development of atherosclerotic plaques.…”
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Secretory Products of Trichinella spiralis Muscle Larvae and Immunomodulation: Implication for Autoimmune Diseases, Allergies, and Malignancies by Ljiljana Sofronic-Milosavljevic, Natasa Ilic, Elena Pinelli, Alisa Gruden-Movsesijan

“…Those products can successfully modulate parasite-specific immune responses as well as responses to unrelated antigens (either self or nonself in origin), providing an anti-inflammatory milieu and maintaining homeostasis. …”
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Application of Natural Antioxidants as Feed Additives in Aquaculture: A Review by Xiaodan Hu, Wenjing Ma, Disen Zhang, Zikun Tian, Yuanqiang Yang, Yi Huang, Yuhang Hong

“…In aquaculture, natural antioxidants have gained increasing attention as sustainable feed additives to mitigate oxidative damage, enhance immune responses, and improve overall growth performance. …”
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Investigation into changes in inflammatory and immune cell markers in pre-diabetic patients from Durban, South Africa by Nomusa Christina Mzimela, Aubrey Mbulelo Sosibo, Phikelelani Siphosethu Ngubane, Andile Khathi

“…Studies also indicate that this condition is associated with aberrant immune responses that are also influenced by environmental factors. …”
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Increased thyroxine levels of patients with allergic rhinitis by Violeta Lokaj-Berisha, Besa Gacaferri Lumezi

“…The study highlights the complex interplay between metabolic, endocrine, and immune responses in respiratory allergies. Elevated serum IgE levels and alterations in thyroid function, particularly among males, suggest potential pathways for targeted therapeutic interventions. …”
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BA inhibits LPS-stimulated inflammatory response and apoptosis in human middle ear epithelial cells by regulating the Nf-Kb/Iκbα axis by He Qian, Cai Yanzhi, Kong Meihua

“…The pathogenesis of OM is multifaceted, encompassing a variety of factors including bacterial or viral infections, host immune responses, and the function of middle ear epithelial cells. …”
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Immunological Approaches and Different Strategies for Vaccine Development Against SARS-COV-2 by Muhammed Babakir-Mina

“…On the base on immune response detected in recovered patients, scientists have started to develop the vaccines. …”
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Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment by Katherine M. Ranard, Bruce Appel

“…Low DHA status is linked to altered immune responses, white matter defects, impaired vision, and an increased risk of psychiatric disorders during development. …”
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Unconventional secretion of unglycosylated ORF8 is critical for the cytokine storm during SARS-CoV-2 infection. by Xiaoyuan Lin, Beibei Fu, Yan Xiong, Na Xing, Weiwei Xue, Dong Guo, Mohamed Zaky, Krishna Pavani, Dusan Kunec, Jakob Trimpert, Haibo Wu

“…In addition to structural proteins such as Spike and Envelope, the functional roles of non-structural and accessory proteins in regulating viral life cycle and host immune responses remain to be understood. Here, we show that open reading frame 8 (ORF8) acts as messenger for inter-cellular communication between alveolar epithelial cells and macrophages during SARS-CoV-2 infection. …”
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The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung by Matthew S. Twigg, Simon Brockbank, Philip Lowry, S. Peter FitzGerald, Clifford Taggart, Sinéad Weldon

“…The general effects of this protease/antiprotease imbalance are impaired mucus clearance, increased and self-perpetuating inflammation, and impaired immune responses and tissue. To restore this balance antiproteases have been suggested as potential therapeutics or therapeutic targets. …”
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Pharmacological inhibition of key metabolic pathways attenuates Leishmania spp infection in macrophages. by Elaine Carvalho de Oliveira, Rafael Tibúrcio, Gabriela Duarte, Amanda Lago, Léon de Melo, Sara Nunes, Gustavo Gastão Davanzo, Ana Júlia Martins, Bruno Vinagre Ribeiro, Deborah Mothé, Juliana B P Menezes, Patrícia Veras, Natalia Tavares, Pedro M Moraes-Vieira, Cláudia Ida Brodskyn

“…Here, we demonstrate that despite differences in their mechanisms for evading host immune responses, L. amazonensis and L. braziliensis induce comparable disruptions in key metabolic pathways. …”
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Therapeutic Approaches in COVID-19 Patients: The Role of the Renin-Angiotensin System by Farzaneh Ketabchi, Sina Jamzad

“…However, the administration of COX inhibitors can reduce innate immune responses and have the opposite effect. A few studies suggest benefits of low-dose radiation therapy (LDR) in treating acute respiratory distress syndrome in COVID-19 patients. …”
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