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661
Susceptibility of Porphyromonas gingivalis and Streptococcus mutans to Antibacterial Effect from Mammea americana
Published 2014-01-01“…These microorganisms trigger inflammatory and immune responses in the host. Currently, medicinal plants are treatment options for these oral diseases. …”
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662
Advances in Illuminating Prostate Cancer with Emerging Phototherapies
Published 2025-01-01“…PDT employs photosensitizers to produce reactive oxygen species, thereby stimulating anti-tumor immune responses, disrupting the tumor microvasculature and/or inducing aopotitic or necrotic cell death. …”
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663
The role of BATF in immune cell differentiation and autoimmune diseases
Published 2025-01-01“…Recent studies have demonstrated that BATF not only plays pivotal roles in innate and adaptive immune responses but also acts as a crucial factor in the differentiation and function of various immune cells. …”
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664
Immunotherapeutic Potential of Lactobacillus Species as Immune Checkpoint Inhibitors in Cancer Immunotherapy
Published 2025-01-01“…These probiotics influence immune responses through interactions with immune cells such as dendritic cells, macrophages, and T cells. …”
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665
A pair of promising immune checkpoints PSGL-1 and VISTA from immunotolerance to immunotherapy
Published 2024-12-01“…Abstract Immune checkpoints are crucial for regulating immune responses and maintaining self-tolerance, as they play a pivotal role in preventing autoimmunity and facilitating tumor immune evasion. …”
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666
The TIR Domain Containing Locus of Enterococcus faecalis Is Predominant among Urinary Tract Infection Isolates and Downregulates Host Inflammatory Response
Published 2014-01-01“…When transiently expressed in cultured eukaryotic cells, TcpF caused suppression of TLR2-dependent NF-κB activation suggesting for TcpF a role as a factor in E. faecalis that benefits colonization by modulating the host’s immune responses.…”
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667
A population model capturing dynamics of tuberculosis granulomas predicts host infection outcomes
Published 2015-01-01“…The model also predicts a dual role for granuloma development in LNs during Mtb infection: in early phases of infection granulomas suppress infection by providing additional antigens to the site of immune priming; however, this induces a more rapid reactivation at later stages by disrupting immune responses. We identify mechanisms that strongly correlate with better host-level outcomes, including elimination of uncontained lung granulomas by inducing low levels of lung tissue damage and inhibition of bacteria dissemination within the lung.…”
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668
Gut Microbiota–Tumor Microenvironment Interactions: Mechanisms and Clinical Implications for Immune Checkpoint Inhibitor Efficacy in Cancer
Published 2025-01-01“…Emerging evidence suggests that the gut microbiota plays a pivotal role in modulating immune responses at the tumor site and may even influence treatment outcomes in cancer patients receiving ICIs. …”
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669
Depletion of Regulatory T Cells in a Mouse Experimental Glioma Model through Anti-CD25 Treatment Results in the Infiltration of Non-Immunosuppressive Myeloid Cells in the Brain
Published 2013-01-01“…The recruitment and activation of regulatory T cells (Tregs) in the micro-environment of malignant brain tumors has detrimental effects on antitumoral immune responses. Hence, local elimination of Tregs within the tumor micro-environment represents a highly valuable tool from both a fundamental and clinical perspective. …”
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670
Immunomodulation by Gut Microbiota: Role of Toll-Like Receptor Expressed by T Cells
Published 2014-01-01“…A close relationship exists between gut microbiota and immune responses. An imbalance of this relationship can determine local and systemic immune diseases. …”
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671
Vitreous Mediators in Retinal Hypoxic Diseases
Published 2013-01-01“…Cytokines and chemokines are multifunctional mediators that can direct the recruitment of leukocytes to sites of inflammation, promote the process, enhance immune responses, and promote stem cell survival, development, and homeostasis. …”
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672
Cytokines and HCV-Related Disorders
Published 2012-01-01“…The complex cytokine network operating during initial infection allows a coordinated, effective development of both innate and adaptive immune responses. However, HCV interferes with cytokines at various levels and escapes immune response by inducing a T-helper (Th)2/T cytotoxic 2 cytokine profile. …”
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673
Carcinogenic and anticancer activities of microbiota-derived secondary bile acids
Published 2025-01-01“…Conversely, some SBAs exhibit anticancer properties by inducing apoptosis, inhibiting cell proliferation, and modulating immune responses. The article also discusses the complex interplay between SBAs and the host’s genetic and environmental factors, highlighting potential therapeutic implications and the need for targeted strategies to mitigate risks while harnessing beneficial effects. …”
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674
Platelet microparticles level in juvenile idiopathic arthritis: A pediatric population-based cross-sectional study in a tertiary care center
Published 2019-01-01“…Background: Platelet-derived microparticles (PMPs) are small vesicles that are released from the plasma membrane upon platelet activation, which are then involved in haemostasis, vascular health, and have recently been shown to be intimately involved in immune responses. Aims and Objectives: We aimed to evaluate the level of plasma Platelet-derived micro particles in children with JIA and to assess the relationship between PMP levels and disease activity in JIA. …”
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675
Claudin-11 regulates immunological barrier formation and spermatogonial proliferation through stem cell factor
Published 2025-01-01“…This suggests that adaptive immune responses to spermatogenic cells are not a cause of defective spermatogenesis in Cldn11-deficient mice. …”
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676
Effect of amniotic fluid on hair follicle growth
Published 2025-12-01“…Both irradiated (FAFI) and non-irradiated (FAF) hAF were assessed for their efficacy and safety in promoting hair growth and modulating immune responses in a rat model of hair loss. The study examined HF regeneration, transition to the anagen phase, and macrophage polarization from the pro-inflammatory M1 phenotype to the anti-inflammatory M2 phenotype.Results: Both FAF and FAFI treatments significantly increased HF density, with FAFI exhibiting enhanced effects. …”
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677
Centrality of Hygienic Honey Bee Workers in Colony Social Networks
Published 2025-01-01“…This work highlights the importance of considering the benefits of remaining socially integrated in important information networks and the temporal limitations for how quickly organized immune responses can occur in response to potential infections.…”
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678
Holding the Inflammatory System in Check: TLRs and Their Targeted Therapy in Asthma
Published 2016-01-01“…TLRs are the primary proteins associated with the innate and adaptive immune responses to these fatal factors and play an important role in recognizing pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), which initiates the downstream immune response. …”
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679
Secretory Products of Trichinella spiralis Muscle Larvae and Immunomodulation: Implication for Autoimmune Diseases, Allergies, and Malignancies
Published 2015-01-01“…Those products can successfully modulate parasite-specific immune responses as well as responses to unrelated antigens (either self or nonself in origin), providing an anti-inflammatory milieu and maintaining homeostasis. …”
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680
Application of Natural Antioxidants as Feed Additives in Aquaculture: A Review
Published 2025-01-01“…In aquaculture, natural antioxidants have gained increasing attention as sustainable feed additives to mitigate oxidative damage, enhance immune responses, and improve overall growth performance. …”
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