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561
Association of Major Histocompatibility Complex Polymorphism With Acute Phase Response in Broiler Chicken
Published 2024-11-01“…Lastly, the correlation between immune responses and MHC alleles was investigated to identify the most effective alleles in a stress‐related situation. …”
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562
Regulation of Tumor Immunity by Tumor/Dendritic Cell Fusions
Published 2010-01-01“…Although DCs-based vaccine such as fusions of whole tumor cells and DCs has been proven to be clinically safe and is efficient to enhance antitumor immune responses for inducing effective immune response and for breaking T-cell tolerance to tumor-associated antigens (TAAs), only a limited success has occurred in clinical trials. …”
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563
A KIF20A-based thermosensitive hydrogel vaccine effectively potentiates immune checkpoint blockade therapy for hepatocellular carcinoma
Published 2025-01-01“…The inherently weak immune responses in HCC necessitate novel strategies to improve anti-tumor immunity and synergize with ICB therapy. …”
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564
Toll-like receptors in atopic dermatitis: pathogenesis and therapeutic implications
Published 2025-02-01“…Patient heterogeneity, including the presence or absence of polymorphisms, variations in TLR expression levels, and differences in immune responses, underscores the need for personalized therapeutic approaches.…”
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565
A novel therapeutic multiepitope vaccine based on oncoprotein E6 and E7 of HPV 16 and 18: An in silico approach
Published 2024-09-01“…Computational analysis indicated the vaccine could induce immune responses through the elevation of cytokine levels after the third injection, antibody production, activation of memory B and T cells, and promotion of increased dendritic cell counts. …”
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566
Autoimmune hepatitis under the COVID-19 veil: an analysis of the nature of potential associations
Published 2025-01-01“…For instance, SARS-CoV-2 may impact autoimmunity through mechanisms such as excessive stimulation of immune responses and molecular mimicry, particularly in genetically predisposed individuals. …”
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567
Developing and Activated T Cell Survival Depends on Differential Signaling Pathways to Regulate Anti-Apoptotic Bcl-xL
Published 2012-01-01“…Survival of T cells in both the central and peripheral immune system determines its ultimate function in the regulation of immune responses. In the thymus, developing T cells undergo positive and negative selection to generate a T cell repertoire that responds to foreign, but not self, antigens. …”
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568
A subunit vaccine Ag85A-LpqH focusing on humoral immunity provides substantial protection against tuberculosis in mice
Published 2025-01-01“…This vaccine can induce robust antibody responses, as well as T cell immune responses especially strong CD8+ T cell responses. …”
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569
Leveraging mRNA technology for antigen based immuno-oncology therapies
Published 2025-01-01“…Selecting suitable tumor antigens is the key step to devising effective vaccinations and amplifying the immune response. Tumor neoantigens are de novo epitopes derived from somatic mutations, avoiding T-cell central tolerance of self-epitopes and inducing immune responses to tumors. …”
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570
Roitt's essential immunology /
Published 2017Table of Contents: “…Innate immunity -- Specific acquired immunity -- Antibodies -- Membrane receptors for antigen -- Antigen-specific recognition -- Immunological methods and applications [JS2] -- The anatomy of the immune response -- Lymphocyte activation -- The production of effectors -- The regulation of the immune response -- Development and evolution of the immune response -- Adversarial strategies during infection -- Vaccines -- Immunodeficiency -- Allergy and other hypersensitivities -- Transplantation -- Tumor immunology -- Autoimmune diseases.…”
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571
A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease
Published 2019-01-01“…In this review, we have systemically reviewed the pathogenesis of IBD and highlighted recent advances in host genetic factors, gut microbiota, and environmental factors and, especially, in abnormal innate and adaptive immune responses and their interactions, which may hold the keys to identify novel predictive or prognostic biomarkers and develop new therapies.…”
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572
The therapeutic potential of bacterial lysates: applications and future perspectives
Published 2024-12-01“…The use of bacterial lysates in therapy has gained momentum due to their ability to modulate host immune responses. These preparations, derived from bacterial cell lysis, contain antigenic components that stimulate both innate and adaptive immunity. …”
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573
Effect of microencapsulated Fiber2-displaying probiotics loaded with inulin nanoparticles on immunity against fowl adenovirus serotype 4 in chickens
Published 2025-02-01“…Animal experiments demonstrated that oral immunization with Micro-E/Fiber2-PINs significantly enhanced humoral and cellular immune responses, relieved inflammatory injury in FAdV-targeted organs, and improved survival rate of challenged chickens. …”
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574
Substrate curvature influences cytoskeletal rearrangement and modulates macrophage phenotype
Published 2025-01-01“…IntroductionInflammation is a vital immune response, tightly orchestrated through both biochemical and biophysical cues. …”
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575
Enhanced targeted treatment of cervical cancer using nanoparticle-based doxycycline delivery system
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576
Liquid biopsy approaches to capture tumor evolution and clinical outcomes during cancer immunotherapy
Published 2023-01-01“…While liquid biopsies may provide a rapid and accurate evaluation of tumor burden dynamics during immunotherapy, the complexity of antitumor immune responses is not fully captured through single-feature ctDNA analyses. …”
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577
Genetic diversity leads to differential inflammatory responses to cigarette smoke in mice
Published 2025-01-01“…This approach is particularly valuable in understanding diverse immune responses to disease by environmental exposures. …”
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578
Next-generation sequencing and immuno-informatics for designing a multi-epitope vaccine against HSV-1-induced uveitis
Published 2025-01-01“…The in-silico results indicate the vaccine’s potential efficacy in activating immune responses. Future experimental validation and clinical studies are necessary to confirm the safety and efficacy of this proposed vaccine in managing uveitis and preserving vision.…”
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579
Innovative epitopes in Staphylococcal Protein-A an immuno-informatics approach to combat MDR-MRSA infections
Published 2025-01-01“…Staphylococcal Protein A (SpA), a crucial virulence factor of MRSA, undermines host immune responses, making it an attractive target for vaccine development. …”
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580
Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials
Published 2025-02-01“…In summary, this review presents compelling evidence positioning Clec9a as a promising target for DC-based tumor immunotherapy, capable of enhancing the efficacy of vaccines and immune responses while minimizing adverse effects.…”
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