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521
Cytomegalovirus in the Neonate: Immune Correlates of Infection and Protection
Published 2013-01-01“…A better understanding of immune responses that prevent and/or predispose to infection will help in the development of novel vaccine strategies.…”
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522
The Immunomodulatory Potential of Wharton’s Jelly Mesenchymal Stem/Stromal Cells
Published 2019-01-01“…This text highlights information on how WJ-MSC affect immune responses in comparison with other sources of MSC.…”
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523
Dynamic Roles of RNA and RNA Epigenetics in HTLV-1 Biology
Published 2025-01-01“…Viruses, particularly retroviruses like human T-cell leukemia virus type 1 (HTLV-1), rely heavily on RNA and RNA post-transcriptional modifications to regulate the viral lifecycle, pathogenesis, and evasion of host immune responses. With the emergence of new sequencing technologies in the last decade, our ability to dissect the intricacies of RNA has flourished. …”
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524
Evolution of the C-Type Lectin-Like Receptor Genes of the DECTIN-1 Cluster in the NK Gene Complex
Published 2012-01-01“…Pattern recognition receptors are crucial in initiating and shaping innate and adaptive immune responses and often belong to families of structurally and evolutionarily related proteins. …”
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525
Saving Death: Apoptosis for Intervention in Transplantation and Autoimmunity
Published 2006-01-01“…Long considered immunologically “bland,” apoptotic cells are now recognized as important modulators of immune responses. The role of apoptosis in immunological homeostasis has been inferred from several findings, for example, induction of tolerance after injection of apoptotic cells and the capacity of APCs like macrophages and DCs to induce and maintain tolerance after phagocytosis of dead cells. …”
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526
Scorpion Venom and the Inflammatory Response
Published 2010-01-01“…Although the pathophysiology of envenomation is complex and not yet fully understood, venom and immune responses are known to trigger the release of inflammatory mediators that are largely mediated by cytokines. …”
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527
The unexpected role of the STING protein in lipid metabolism
Published 2023-04-01“…Detection of cytosolic pathological nucleic acids is a key step for the initiation of innate immune responses. In the past decade, the stimulator of interferon genes (STING) adaptor protein has emerged as a central platform enabling the activation of inflammatory responses in the presence of cytosolic DNAs. …”
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528
Therapeutic potential of mesenchymal stem cells for fungal infections: mechanisms, applications, and challenges
Published 2025-01-01“…In this study, the therapeutic potential of MSCs for FIs was reviewed, including their roles played by secreting antimicrobial peptides, regulating immune responses, and promoting tissue repair. Meanwhile, the status of research on MSCs in FIs and the controversies were also discussed. …”
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529
Spatial-Temporal Patterns and Inflammatory Factors of Bone Matrix Remodeling
Published 2021-01-01“…Studies show that the circadian oscillations of these factors in bone ECM potentially influence the interactions between immune responses and bone formation. More importantly, mesenchymal stem cells (MSCs) within the specific microenvironments provide the regenerative potential for tissue remodeling. …”
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530
Clinical Outcomes of Specific Immunotherapy in Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis
Published 2017-01-01“…The effects of specific immunotherapy were compared with those of nonspecific immunotherapy and the meta-analysis was executed with results regarding the overall survival (OS), immune responses data, and serum cancer markers data. The pooled analysis was performed by using the random-effects model. …”
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531
Nanomaterials in cancer immunotherapy: targeting cancer-associated fibroblasts
Published 2025-01-01“…Their aptitude for modulating immune responses, amplifying drug efficacy through precise delivery, and discerningly focusing on cells within the TME situates nanomaterials as formidable tools to transcend the boundaries set by conventional treatments. …”
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532
The Opportunistic Pathogen Listeria monocytogenes: Pathogenicity and Interaction with the Mucosal Immune System
Published 2010-01-01“…Here, we discuss recent advances in our understanding of the interaction of L. monocytogenes with the host immune system that triggers the antibacterial immune responses on the mucosal surfaces of the human gastrointestinal tract.…”
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533
Diverse Roles of Inhibitor of Differentiation 2 in Adaptive Immunity
Published 2011-01-01“…While its role in early lymphopoiesis has been well characterized, new roles in adaptive immune responses have recently been uncovered opening exciting new directions for investigation. …”
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534
HMBG1 as a Driver of Inflammatory and Immune Processes in the Pathogenesis of Ocular Diseases
Published 2018-01-01“…In this review, we summarize current knowledge on HMGB1 as a ligand that can evoke inflammation and immune responses in ocular diseases.…”
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535
Immunoregulation of NKT Cells in Systemic Lupus Erythematosus
Published 2015-01-01“…Natural killer T (NKT) cells are innate lymphocytes that play a regulatory role during broad range of immune responses. A number of studies demonstrated that the quantity and quality of invariant NKT (iNKT) cells showed marked defects in SLE patients in comparison to healthy controls. …”
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536
Role of Zinc Signaling in the Regulation of Mast Cell-, Basophil-, and T Cell-Mediated Allergic Responses
Published 2018-01-01“…Although many molecules involved in these processes have zinc-binding motifs, the molecular mechanisms and the role of zinc in immune responses have not been elucidated. We and others have demonstrated that zinc signaling plays diverse and specific roles in vivo and in vitro in studies using knockout mice lacking zinc transporter function and metallothionein function. …”
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537
Desmoplastic reaction in the microenvironment of head and neck and other solid tumors: the therapeutic barrier
Published 2025-02-01“…The interaction between cancer-associated fibroblasts (CAFs) and TME influences immune responses, including resistance to immunotherapy. …”
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538
Skin Immune Landscape: Inside and Outside the Organism
Published 2017-01-01“…This review aims at providing basic background information on the cutaneous immune system from major cellular and molecular players and the impact of its microbiota on the well-coordinated immune responses in host defense.…”
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539
The effects of the ketone body ?-hydroxybutyrate on the neuronal transcriptome
Published 2025-02-01“…Our results suggest that under normal conditions, BHBs primary actions include modulation of cellular neuronal immune responses. …”
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540
Pain Neuroscience Education for Acute Pain
Published 2024-06-01“…However, modern pain science has illuminated the complexity of the human pain experience, incorporating psychosocial elements, nervous system sensitization, immune responses, and structural changes in the brain as factors. …”
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