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521
Effects of Escherichia coli Nissle 1917 on immunity, blood constituents, antioxidant capacity, egg quality and performance in laying Japanese quail
Published 2025-02-01“…This study was conducted to evaluate the effects of E.coli Nissle 1917 (EcN) on immune responses, blood parameters, oxidative stress, egg quality, and performance of laying Japanese quail. …”
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522
cGAS/STING signaling pathway in gynecological malignancies: From molecular mechanisms to therapeutic values
Published 2025-01-01“…The cGAS/STING signaling pathway, a pivotal mechanism in innate immunity, detects cytosolic DNA from pathogens or cellular damage, triggering immune responses via type I interferons and inflammatory cytokines. …”
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523
Cytokine Immunopathogenesis of Enterovirus 71 Brain Stem Encephalitis
Published 2012-01-01“…EV71 replicates in leukocytes, endothelial cells, and dendritic cells resulting in the production of immune and inflammatory mediators that shape innate and acquired immune responses and the complications of disease. Cytokines, as a part of innate immunity, favor the development of antiviral and Th1 immune responses. …”
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524
Developing anti-TDE vaccine for sensitizing cancer cells to treatment and metastasis control
Published 2025-01-01“…TDEs support cancer progression by suppressing anti-tumor immune responses, promoting metastasis, and conferring drug resistance. …”
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525
T Helper 17 Cells in Autoimmune Liver Diseases
Published 2013-01-01“…In contrast, another distinct subset of T cells, regulatory T cells (Treg), downregulate immune responses and play an important role in maintaining self-tolerance. …”
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526
NF-κB signaling and the tumor microenvironment in osteosarcoma: implications for immune evasion and therapeutic resistance
Published 2025-01-01“…Osteosarcoma, a highly aggressive malignancy with a generally poor prognosis, is characterized by tumor cells’ ability to evade immune responses and resist treatment. The nuclear transcription factor NF-κB signaling pathway is crucial in regulating inflammatory and immune reactions. …”
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527
The Application of Traditional Chinese Medicine-Derived Formulations in Cancer Immunotherapy: A Review
Published 2025-01-01“…It explores the mechanisms by which TCM augments immune responses, particularly focusing on how these formulations influence both innate and adaptive immunity. …”
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528
Effect of gut microbiota changes on cytokines IL-10 and IL-17 levels in liver transplantation patients
Published 2025-01-01“…Cytokines, small signaling molecules, significantly influence immune responses during and post-liver transplantation. …”
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529
Ex Vivo Restimulation of Human PBMC Expands a CD3+CD4-CD8-γδ+ T Cell Population That Can Confound the Evaluation of CD4 and CD8 T Cell Responses to Vaccination
Published 2013-01-01“…The measurement of vaccine-induced humoral and CD4+ and CD8+ cellular immune responses represents an important correlate of vaccine efficacy. …”
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530
Vibrio Dynamics and Health Status of Pacific White Shrimp Fed with Cinnamaldehyde-Containing Feed
Published 2022-08-01“…The decrease of green Vibrio bacteria and increased colonization of yellow Vibrio bacteria were correlated with immune responses. The best treatment in this study is treatment C.…”
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531
SOCS1, a Negative Regulator of Cytokine Signals and TLR Responses, in Human Liver Diseases
Published 2010-01-01“…Toll-like receptor (TLR) signaling pathways are strictly coordinated by several mechanisms to regulate adequate innate immune responses. Recent lines of evidence indicate that the suppressor of cytokine signaling (SOCS) family proteins, originally identified as negative-feedback regulators in cytokine signaling, are involved in the regulation of TLR-mediated immune responses. …”
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532
The Influence of Nanoparticle on Vaccine Responses against Bacterial Infection
Published 2022-01-01“…Nanoparticles could function as a drug delivery tool, as an adjuvant to promote antigen processing, and as an immune modulator to induce immune responses. These nanoparticles generate immune responses through activating immune cells as well as through the production of antibody responses. …”
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533
Vaccine adjuvants for immunotherapy: type, mechanisms and clinical applications
Published 2025-02-01“…These emerging agents hold promise for enhancing immune responses while tailoring therapies to specific disease contexts, from cancer to infectious diseases. …”
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534
Midgut immune profiling and functional characterization of Aedes aegypti ABC transporter gene(s) using systemic and local bacterial challenges
Published 2025-01-01“…Conclusions The silencing of AaeABCG3 modulated the mosquito midgut immune response and disturbed the midgut microbiota homeostasis. …”
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535
Vascularized Composite Allograft Rejection Is Delayed by Intrajejunal Treatment with Donor Splenocytes without Concomitant Immunosuppressants
Published 2012-01-01“…Recipients’ immune responses were assessed by mixed lymphocyte reaction (MLR) against donor antigen and controls. …”
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536
Advancing veterinary vaccines design through trained immunity insights
Published 2025-01-01“…We analyze key molecular mechanisms, including the shift to aerobic glycolysis and sustained epigenetic changes, that enable enhanced immune responses. Strategic approaches for vaccine optimization are proposed, focusing on selecting effective trained immunity inducers, developing innovative adjuvant systems, and achieving synergistic enhancement of immune responses. …”
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537
Beyond Needles: Immunomodulatory Hydrogel-Guided Vaccine Delivery Systems
Published 2024-12-01“…Additionally, this review addresses critical challenges, including safety, scalability, and regulatory considerations, offering insights into hydrogel-guided strategies for eliciting targeted immune responses and advancing global immunization efforts.…”
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538
Antigen Presentation in the Gut
Published 1990-01-01“…Dendritic cells isolated from normal human colon are potent inducers of primary immune responses and express high levels of class lI MHC proteins. …”
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539
PI3K Functions in Cancer Progression, Anticancer Immunity and Immune Evasion by Tumors
Published 2011-01-01“…The phosphatidylinositol 3-kinase (PI3K) pathway regulates multiple cellular processes which underlie immune responses against pathogens or malignant cells. …”
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540
Dysregulation of NK and CD8+T Cells by the Microbiota Promotes the Progression of Lung Cancer
Published 2022-01-01“…Alterations in the amount and dominant species of the microbiota can reshape the immune response of the body and lead to a variety of lung diseases, including cancer. …”
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