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  1. 521

    Effects of Escherichia coli Nissle 1917 on immunity, blood constituents, antioxidant capacity, egg quality and performance in laying Japanese quail by Asghar Sedaghat, Mohammad Amir Karimi Torshizi, Mohammad Reza Soleimani

    Published 2025-02-01
    “…This study was conducted to evaluate the effects of E.coli Nissle 1917 (EcN) on immune responses, blood parameters, oxidative stress, egg quality, and performance of laying Japanese quail. …”
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    Article
  2. 522

    cGAS/STING signaling pathway in gynecological malignancies: From molecular mechanisms to therapeutic values by Danyang Zhang, Bingxue Zhang

    Published 2025-01-01
    “…The cGAS/STING signaling pathway, a pivotal mechanism in innate immunity, detects cytosolic DNA from pathogens or cellular damage, triggering immune responses via type I interferons and inflammatory cytokines. …”
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    Article
  3. 523

    Cytokine Immunopathogenesis of Enterovirus 71 Brain Stem Encephalitis by Shih-Min Wang, Huan-Yao Lei, Ching-Chuan Liu

    Published 2012-01-01
    “…EV71 replicates in leukocytes, endothelial cells, and dendritic cells resulting in the production of immune and inflammatory mediators that shape innate and acquired immune responses and the complications of disease. Cytokines, as a part of innate immunity, favor the development of antiviral and Th1 immune responses. …”
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    Article
  4. 524

    Developing anti-TDE vaccine for sensitizing cancer cells to treatment and metastasis control by Stephene S. Meena, Benson K. Kosgei, Geofrey F. Soko, Cheng Tingjun, Ramadhani Chambuso, Julius Mwaiselage, Ray P. S. Han

    Published 2025-01-01
    “…TDEs support cancer progression by suppressing anti-tumor immune responses, promoting metastasis, and conferring drug resistance. …”
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    Article
  5. 525

    T Helper 17 Cells in Autoimmune Liver Diseases by Masanori Abe, Yoichi Hiasa, Morikazu Onji

    Published 2013-01-01
    “…In contrast, another distinct subset of T cells, regulatory T cells (Treg), downregulate immune responses and play an important role in maintaining self-tolerance. …”
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    Article
  6. 526

    NF-κB signaling and the tumor microenvironment in osteosarcoma: implications for immune evasion and therapeutic resistance by Shaoyan Shi, Xuehai Ou, Chao Liu, Rui Li, Qianjin Zheng, Leiming Hu

    Published 2025-01-01
    “…Osteosarcoma, a highly aggressive malignancy with a generally poor prognosis, is characterized by tumor cells’ ability to evade immune responses and resist treatment. The nuclear transcription factor NF-κB signaling pathway is crucial in regulating inflammatory and immune reactions. …”
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    Article
  7. 527

    The Application of Traditional Chinese Medicine-Derived Formulations in Cancer Immunotherapy: A Review by Li Y, Li C, Fan J, Liu Y, Xu Y, Pang G

    Published 2025-01-01
    “…It explores the mechanisms by which TCM augments immune responses, particularly focusing on how these formulations influence both innate and adaptive immunity. …”
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  10. 530

    Vibrio Dynamics and Health Status of Pacific White Shrimp Fed with Cinnamaldehyde-Containing Feed by Dian Eka Ramadhani, Andri Hendriana, Dinamella Wahjuningrum, Muhammad Arif Mulya

    Published 2022-08-01
    “…The decrease of green Vibrio bacteria and increased colonization of yellow Vibrio bacteria were correlated with immune responses. The best treatment in this study is treatment C.…”
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    Article
  11. 531

    SOCS1, a Negative Regulator of Cytokine Signals and TLR Responses, in Human Liver Diseases by Minoru Fujimoto, Tetsuji Naka

    Published 2010-01-01
    “…Toll-like receptor (TLR) signaling pathways are strictly coordinated by several mechanisms to regulate adequate innate immune responses. Recent lines of evidence indicate that the suppressor of cytokine signaling (SOCS) family proteins, originally identified as negative-feedback regulators in cytokine signaling, are involved in the regulation of TLR-mediated immune responses. …”
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    Article
  12. 532

    The Influence of Nanoparticle on Vaccine Responses against Bacterial Infection by Sareh Bagheri-Josheghani, Bita Bakhshi, Shahin Najar-peerayeh

    Published 2022-01-01
    “…Nanoparticles could function as a drug delivery tool, as an adjuvant to promote antigen processing, and as an immune modulator to induce immune responses. These nanoparticles generate immune responses through activating immune cells as well as through the production of antibody responses. …”
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    Article
  13. 533

    Vaccine adjuvants for immunotherapy: type, mechanisms and clinical applications by Nimeet Desai, Sherrin Gotru, Sagar Salave, Lalitkumar K. Vora

    Published 2025-02-01
    “…These emerging agents hold promise for enhancing immune responses while tailoring therapies to specific disease contexts, from cancer to infectious diseases. …”
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    Article
  14. 534

    Midgut immune profiling and functional characterization of Aedes aegypti ABC transporter gene(s) using systemic and local bacterial challenges by Vikas Kumar, Shilpi Garg, Diksha Sisodia, Lalita Gupta, Sanjeev Kumar, Vishal Saxena

    Published 2025-01-01
    “…Conclusions The silencing of AaeABCG3 modulated the mosquito midgut immune response and disturbed the midgut microbiota homeostasis. …”
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  15. 535
  16. 536

    Advancing veterinary vaccines design through trained immunity insights by Xin Wang, Xin Wang, Xin Wang, Xin Wang, Guohua Yu, Guohua Yu, Guohua Yu

    Published 2025-01-01
    “…We analyze key molecular mechanisms, including the shift to aerobic glycolysis and sustained epigenetic changes, that enable enhanced immune responses. Strategic approaches for vaccine optimization are proposed, focusing on selecting effective trained immunity inducers, developing innovative adjuvant systems, and achieving synergistic enhancement of immune responses. …”
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    Article
  17. 537

    Beyond Needles: Immunomodulatory Hydrogel-Guided Vaccine Delivery Systems by Md Mohosin Rana, Cigdem Demirkaya, Hector De la Hoz Siegler

    Published 2024-12-01
    “…Additionally, this review addresses critical challenges, including safety, scalability, and regulatory considerations, offering insights into hydrogel-guided strategies for eliciting targeted immune responses and advancing global immunization efforts.…”
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    Article
  18. 538

    Antigen Presentation in the Gut by W Doe, P Pavli

    Published 1990-01-01
    “…Dendritic cells isolated from normal human colon are potent inducers of primary immune responses and express high levels of class lI MHC proteins. …”
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    Article
  19. 539

    PI3K Functions in Cancer Progression, Anticancer Immunity and Immune Evasion by Tumors by Francesco Dituri, Antonio Mazzocca, Gianluigi Giannelli, Salvatore Antonaci

    Published 2011-01-01
    “…The phosphatidylinositol 3-kinase (PI3K) pathway regulates multiple cellular processes which underlie immune responses against pathogens or malignant cells. …”
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  20. 540

    Dysregulation of NK and CD8+T Cells by the Microbiota Promotes the Progression of Lung Cancer by Shouxin Hu, Yanfang Zha, Wenwen Yang, Kele Cui, Min Cheng

    Published 2022-01-01
    “…Alterations in the amount and dominant species of the microbiota can reshape the immune response of the body and lead to a variety of lung diseases, including cancer. …”
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    Article