Comparison of global transcriptomes for nontyphoidal Salmonella clinical isolates from pediatric patients with and without bacteremia after their interaction with human intestinal... by Buyandelger Batsaikhan, Pei-Chun Lin, Katsumi Shigemura, Yu-Wei Wu, Reo Onishi, Pei-Ru Chang, Hung-Yen Cheng, Shiuh-Bin Fang

“…Significant regulation of certain SPI genes in bacteremic NTS strains after Caco-2 cell priming; bacteremia development might be influenced by the host immune response and the extent to which specific metabolism pathways in NTS strains can be prevented from invading the bloodstream.…”
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Comprehensive analysis of gene expressions in ileal mucosa of chickens fed paddy rice and their IgA response to oral vaccination by M. Yamamoto, A. Ueno, H. Watanabe, M. Okamoto, K. Furukawa, A. Murai

“…Infectious bursal disease virus (IBDV) vaccine were orally administered to chickens fed corn or paddy rice to examine the intestinal immune response. Paddy rice ingestion diminished both the total IgA concentration and IBDV-specific IgA in the bile. …”
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Expression Profile of Genes Potentially Associated with Adequate Glycemic Control in Patients with Type 2 Diabetes Mellitus by Sâmia Cruz Tfaile Corbi, Alliny Souza Bastos, Rafael Nepomuceno, Thamiris Cirelli, Raquel Alves dos Santos, Catarina Satie Takahashi, Cristiane S. Rocha, Silvana Regina Perez Orrico, Claudia V. Maurer-Morelli, Raquel Mantuaneli Scarel-Caminaga

“…This demonstrated a systemic exacerbation of the gene expression related to immune response in T2D patients. Moreover, genes related to lipid metabolisms and DNA replication/repair were influenced by the glycemic control. …”
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Genome analysis of Bifidobacterium adolescentis and investigation of its effects on inflammation and intestinal barrier function by Bo Li, Bo Li, Haoyu Wang, Haoyu Wang, Haoyu Wang, Mengmeng Wang, Mengmeng Wang, Hewei Liang, Hewei Liang, Hewei Liang, Tongyuan Hu, Tongyuan Hu, Tongyuan Hu, Jinlong Yang, Jinlong Yang, Jinlong Yang, Shangyong Li, Xinbi You, Xinbi You, Xinbi You, Binbin Xia, Binbin Xia, Binbin Xia, Yue Yuan, Yue Yuan, Yuanqiang Zou, Yuanqiang Zou, Yinglei Miao, Yinglei Miao, Yang Sun, Yang Sun, Yang Sun

“…It effectively modulated the immune response by reducing the levels of pro-inflammatory cytokines such as IL-6, IL-1β, IL-17A, IFN-γ, and TNF-α, while promoting the secretion of anti-inflammatory cytokines like IL-4, IL-10, and TGF-β1. …”
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Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancers by Sofia V Krasik, Ekaterina A Bryushkova, George V Sharonov, Daria S Myalik, Elizaveta V Shurganova, Dmitry V Komarov, Irina A Shagina, Polina S Shpudeiko, Maria A Turchaninova, Maria T Vakhitova, Igor V Samoylenko, Dimitr T Marinov, Lev V Demidov, Vladimir E Zagaynov, Dmitriy M Chudakov, Ekaterina O Serebrovskaya

“…The current understanding of humoral immune response in cancer patients suggests that tumors may be infiltrated with diffuse B cells of extra-tumoral origin or may develop organized lymphoid structures, where somatic hypermutation and antigen-driven selection occur locally. …”
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Real-world outdoor air exposure effects in a model of the human airway epithelium – A comparison of healthy and asthmatic individuals using a mobile laboratory setting by Pavel Rossner, Helena Libalova, Tereza Cervena, Michal Sima, Zuzana Simova, Kristyna Vrbova, Antonin Ambroz, Zuzana Novakova, Fatima Elzeinova, Anezka Vimrova, Lubos Dittrich, Michal Vojtisek, Martin Pechout, Michal Vojtisek-Lom

“…In samples originating from healthy and asthmatic individuals, we assessed the parameters of toxicity, lipid peroxidation and immune response; we further performed comprehensive monitoring of air pollutants at sampling sites. …”
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Peripheral Expression of IL-6, TNF-α and TGF-β1 in Alzheimer's Disease Patients by Gamze Güven, Pınar Köseoğlu, Ebba Lohmann, Bedia Samancı, Erdi Şahin, Başar Bilgiç, Haşmet Ayhan Hanağası, Hakan Gürvit, Nihan Erginel-Ünaltuna

“…Conclusion: The outcomes of this study suggest a disruption in the peripheral immune response in individuals with AD. The observed decreased expression of cytokine genes in peripheral leukocytes may indicate a contributory mechanism through which peripheral cytokines influence AD pathogenesis.…”
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Disulfidptosis-related gene SLC3A2: a novel prognostic biomarker in nasopharyngeal carcinoma and head and neck squamous cell carcinoma by Xinyi Zhang, Yiqi Lin, Liang Shi, Aixia Zhai, Chao Wu, Qian-Ying Zhu

“…Differentially expressed genes (DEGs) between the high and low SLC3A2 expression groups were primarily involved in cytokine-cytokine receptor interaction and immune response. Finally, in vitro experiments demonstrated that SLC3A2 stimulates tumor cell proliferation and migration. …”
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Blimp-1 orchestrates macrophage polarization and metabolic homeostasis via purine biosynthesis in sepsis by Wenjuan Peng, Qiushi Qin, Rui Li, Yujia Liu, Lan Li, Yue Zhang, Liuluan Zhu

“…Abstract Sepsis is a life-threatening condition characterized by a dysregulated immune response to infection, leading to systemic inflammation and organ dysfunction. …”
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HBV and HBsAg strongly reshape the phenotype, function, and metabolism of DCs according to patients’ clinical stage by Lucile Dumolard, Theophile Gerster, Florent Chuffart, Thomas Decaens, Marie-Noelle Hilleret, Sylvie Larrat, Philippe Saas, Evelyne Jouvin-Marche, David Durantel, Patrice N. Marche, Zuzana Macek Jilkova, Caroline Aspord

“…Dendritic cells (DCs) play important roles in the immune response against HBV but are functionally impaired in patients with chronic hepatitis B. …”
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Differential expressed genes (DEGs) and differential alternative splicing genes (DASs) revealed the common pathologic mechanism of three bacterial pathogens to American eels (Angui... by Zihao Chen, Guanghua Sun, Songlin Guo

“…This analysis also indicated that 7 DAS-encoded proteins in the American eel may play an essential role in the immune response against the three bacterial pathogens. …”
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Acceptance commitment therapy (ACT) for psychological distress associated with inflammatory bowel disease (IBD): protocol for a feasibility trial of the ACTforIBD programme by Richard Gearry, Matthew Fuller-Tyszkiewicz, Andrew McCombie, Peter Gibson, Simon Knowles, Lisa Olive, Antonina Mikocka-Walus, Subhadra Evans, Leanne Raven, Daniel Romano, Eric O, Madeleine Dober, Leesa van Niekerk, Susan Chesterman

“…Introduction Inflammatory bowel disease (IBD) involves an abnormal immune response to healthy gut bacteria. When a person develops IBD, their susceptibility to anxiety and/or depression increases. …”
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Mutation in CDC42 Gene Set as a Response Biomarker for Immune Checkpoint Inhibitor Therapy by Kun Wang, Yingying Zhang, Zhaoming Su, Bei Wang, Yuanyang Zhou, Xiaochu Tong, Chengying Xie, Xiaomin Luo, Sulin Zhang, Mingyue Zheng

“…Furthermore, our analysis of immune response landscapes among different statuses of the CDC42 gene set supports its role as a biomarker. …”
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Mathematical modeling in autoimmune diseases: from theory to clinical application by Yaroslav Ugolkov, Yaroslav Ugolkov, Yaroslav Ugolkov, Antonina Nikitich, Antonina Nikitich, Cristina Leon, Gabriel Helmlinger, Kirill Peskov, Kirill Peskov, Kirill Peskov, Kirill Peskov, Victor Sokolov, Victor Sokolov, Alina Volkova, Alina Volkova

“…Yet, all models strive towards the same goal: to quantitatively describe various aspects of the immune response. The aim of this review was to conduct a systematic review and analysis of mathematical models of autoimmune diseases focused on the mechanistic description of the immune system, to consolidate existing quantitative knowledge on autoimmune processes, and to outline potential directions of interest for future model-based analyses. …”
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MUC2 expression modulates immune infiltration in colorectal cancer by Christophe M. Raynaud, Ayesha Jabeen, Eiman I. Ahmed, Eiman I. Ahmed, Satanay Hubrack, Apryl Sanchez, Shimaa Sherif, Ahmad A. Al-Shaibi, Bernice Lo, Bernice Lo, Jessica Roelands, Davide Bedognetti, Davide Bedognetti, Wouter Hendrickx, Wouter Hendrickx

“…MUC2, a major component of the protective mucus layer in the gastrointestinal tract, has been implicated in CRC progression and immune response regulation.MethodIn this study, we sought to elucidate the relationship between MUC2 expression and immune infiltration within CRC using in vitro models involving two well-established cell lines, HT-29 and LS-174T. …”
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Peripheral Classic and Intermediate Monocyte Subsets as Immune Biomarkers of Systemic Lupus Erythematosus Disease Activity by Amaylia Oehadian, Mohammad Ghozali, Sutiadi Kusuma, Lusi Mersiana, Nadia Gita Ghassani, Fransisca Fransisca, Yitzchak Millenard Sigilipu, Andini Kartikasari, Laniyati Hamijoyo

“…Background: Monocytes are evolutionarily preserved innate immune cells that play essential roles in immune response regulation. Three activated monocyte subsets—classical (CD14++CD16–), intermediate (CD14++CD16+), and nonclassical (CD14+CD16++)—are associated with systemic lupus erythematosus (SLE) progression. …”
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High-Affinity Anti-VISTA Antibody Protects against Sepsis by Inhibition of T Lymphocyte Apoptosis and Suppression of the Inflammatory Response by Tianzhu Tao, Lulong Bo, Teng Li, Longbao Shi, Hui Zhang, Bo Ye, Yuhai Xu, Qingqing Ma, Xiaoming Deng, Guorong Zhang

“…B7 family members and ligands have been identified as critical checkpoints in orchestrating the immune response during sepsis. V-domain Ig suppressor of T cell activation (VISTA) is a new inhibitory immune checkpoint involved in restraining T cell response. …”
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Monitoring of immune activation using biochemical changes in a porcine model of cardiac arrest by Anton Amann, Bernhard Widner, Josef Rieder, Herwig Antretter, Georg Hoffmann, Viktoria Mayr, Hans-Ulrich Strohmenger, Dietmar Fuchs

“…Therefore, monitoring of neopterin concentrations and of tryptophan degradation can serve to detect the extent of T helper cell 1-type immune activation during cellular immune response in humans. In a porcine model of cardiac arrest, we examined the potential use of neopterin measurements and determination of the tryptophan degradation rate as a means of estimating the extent of immune activation. …”
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ZEB1 as a marker of metastasis in thyroid carcinomas: review of literature and own data by P.P. Zinych, V.M. Pushkarev, N.I. Levchuk, M. Tronko

“…ZEB1 is at the forefront of transcription factors involved in the EMT control and promotes tumor cell migration and diffusion, cell stemness, resistance to treatment, metastasizing and evasion of the immune response. Since ZEB1 is a key regulator of EMT, metastasizing is associated with cancer stem cell formation and resistance to therapy in many cancers, including papillary thyroid carcinoma. …”
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Studying the Humoral Response against SARS-CoV-2 in Cuban COVID-19 Recovered Patients by Ivette Orosa Vázquez, Marianniz Díaz, Yaima Zúñiga Rosales, Klayris Amada, Janoi Chang, Ernesto Relova Hernández, Yaima Tundidor, Hilda Roblejo Balbuena, Giselle Monzón, Bárbara Torres Rives, Enrique Noa Romero, Danay Carrillo Valdés, Irinia Valdivia Álvarez, Aurora Delahanty Fernández, Claudia Díaz, Joaquín Solozabal, Mileidys Gil, Belinda Sánchez, Gertrudis Rojas, Beatriz Marcheco, Tania Carmenate

“…Understanding the immune response generated by SARS-CoV-2 is critical for assessing efficient therapeutic protocols and gaining insights into the durability of protective immunity. …”
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