Promising Therapeutic Functions of Bone Marrow Mesenchymal Stem Cells Derived-Exosome in Asthma by Jia-Ying Yuan, Xiang-Yun Wang, Zhi-Ying Tong, Yu-Chao Dong, Jia-Yi Zhao, Yi Zhang, Yan Shang

“…Points also hold that BMMSC-Exo could interfere with airway inflammation and airway remolding in asthma via modulating the immune response, regulating gene expression, adjusting the phenotype of macrophage, etc. …”
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Signatures of selection and candidate genes for adaptation to extreme environmental factors in the genomes of Turano-Mongolian cattle breeds by N. S. Yudin, A. A. Yurchenko, D. M. Larkin

“…The review examines recent work on the origin and evolution of Turano-Mongolian cattle breeds, adaptation of Turano-Mongolian cattle to extreme environments, and summarizes available information on potential candidate genes for climate adaptation of Turano-Mongolian breeds, including cold resistance genes, immune response genes, and high-altitude adaptation genes. …”
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Predictive Role of IL-2R and IL-10 in the Anti-inflammatory Response and Antiplatelet Therapy of Kawasaki Disease: A Retrospective Study by Chun Zhang, Lun Chen, Sun Chen, Yan Bian, Jia Shen, Peng Zhang, JiaNi Song

“…The percentage distribution of lymphocyte subgroups and the altered neutrophil lymphocyte ratio demonstrated that the inflammatory response was dominated by the B cell-mediated humoral immune response before intravenous immunoglobulin (IVIG) treatment, but mainly by T cells via cellular cytotoxic effects after IVIG treatment. …”
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An interpretable framework for inter-observer agreement measurements in TILs scoring on histopathological breast images: A proof-of-principle study. by Abdulkerim Capar, Dursun Ali Ekinci, Mucahit Ertano, M Khalid Khan Niazi, Erva Bengu Balaban, Ibrahim Aloglu, Meryem Dogan, Ziyu Su, Fugen Vardar Aker, Metin Nafi Gurcan

“…Tumor-Infiltrating Lymphocytes (TILs), reflective of the immune response against cancer cells, are pivotal in understanding breast cancer behavior. …”
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Fetal Deaths in SARS-CoV-2-Infected Pregnant Women: A Portuguese Case Series by Ana Rita Mira, João Pedro Pereira, Catrine Dahlstedt-Ferreira, Margarida Enes, Hélder Oliveira Coelho, Ana Beatriz Godinho

“…Placental hypoperfusion and inflammation secondary to maternal immune response seem to play a role in the cascade of events that contribute to fetal death. …”
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Colon Cancer Genetic and Epigenetic Changes, Etiopathogenesis, Risk Factors, Treatment: Literature Review by Gabrielė Ūbaitė, Aurelija Remeikaitė, Justas Žilinskas

“…Innovations such as CRISPR/Cas9 offer new avenues for targeted treatments, while advances in vaccines and liquid biopsy techniques are improving immune response activation and disease monitoring. In addition, diets rich in fiber, antioxidants and healthy fats, as well as the use of probiotics and NSAIDs, are key to reducing cancer risk through their anti-inflammatory effects and promoting gut health. …”
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Inflammatory Cytokines—The Link between Coronavirus Disease and Abortion: A Case‐Control Study by Samar Muayad Alfadhel, Niran Ali Thamer

“…Whereas research studies have not yet determined the exact risk of abortion due to COVID-19 infection, the virus could increase the risk of pregnancy complications through inflammatory cytokines and immune response. Objective: The study highlights prognostic markers for pregnancy complications during COVID-19 infections by testing interleukin-6 (IL-6), interleukin-18 (IL-18), tumor necrosis factors-α (TNF-α), and interferon-γ (INF-γ) in the serum of pregnant women with and without COVID-19. …”
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Neurological Disease-Affected Patients, including Multiple Sclerosis, Are Poor Responders to BKPyV, a Human Polyomavirus by Ilaria Bononi, Elisa Mazzoni, Silvia Pietrobon, Maria Rosa Iaquinta, Andrea Caselli, Elena Torreggiani, Maura Pugliatti, Ilaria Casetta, Massimiliano Castellazzi, Enrico Granieri, Fernanda Martini, Mauro Tognon

“…As control, ELISAs were carried out to verify the immune response against the Epstein-Barr virus (EBV) of patients and controls. …”
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Identification and validation of depression-associated genetic variants in the UK Biobank cohort with transcriptome and DNA methylation analyses in independent cohorts by Muataz S. Lafta, Aleksandr V. Sokolov, Gull Rukh, Helgi B. Schiöth

“…The present study identified six protein-coding genes associated with depression and primarily involved in inflammation (TNXB), neuroplasticity (NCAM1 and LTBP3), immune response (BTN3A2), cell survival (DAG1) and circadian clock modification (FHIT). …”
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Immunogenic characteristics of <i>Avibacterium paragallinаrum</i> (serogroup B) isolates and strains by M. S. Firsova, V. A. Yevgrafova, A. V. Potekhin, R. V. Yashin, O. V. Pruntova, V. S. Russaleyev

“…The vaccine sample based on the antigen of the ApB08 isolate induced an insufficient immune response in poultry when infected with the ApB04 and ApB12 isolates. …”
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Assessment of Interleukin-1β in Saliva of Smoker and Non-smoker Patients with Chronic Periodontitis. by Solav Abdul-Qadir Mustafa, Haween T. Nanakaly, Hozan Wrya Azeez

“…Hence, this reflects the impact of smoking on immune response and its role in the pathogenesis of periodontal disease. …”
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Identification and mechanistic insights of cell senescence-related genes in psoriasis by Guiyan Deng, Cheng Xu, Dunchang Mo

“…Additionally, an immune cell infiltration analysis was performed to understand the roles of these genes in the immune response to psoriasis. Results This study identified 4,913 DEGs in psoriasis, of which 46 were related to cell senescence. …”
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Mitochondria-Targeting Type-I Photodynamic Therapy Based on Phenothiazine for Realizing Enhanced Immunogenic Cancer Cell Death via Mitochondrial Oxidative Stress by Duan Z, Li L, Zhan Q, Chen J, Li Q, Liu R, Tu Y

“…Rh-PTZ can amplify mitochondrial stress-caused immunogenic cell death (ICD) to stimulate the immune response, promote the maturation of sufficient dendritic cells (DCs), enhance the infiltration of immune cells, and alleviate the tumor immunosuppressive microenvironment.Conclusion: The mitochondria-targeting type-I PDT holds promise to enhance photo-immunotherapy for hypoxia tumor treatment and overcoming the limitations of traditional immunotherapy.Keywords: Photo-immunotherapy, immunogenic cell death, Type-I photosensitizers, mitochondrial targeting…”
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RAB3GAP2 dysregulation in adult T-cell leukemia/lymphoma (ATLL) compared to acute lymphoblastic leukemia (ALL): a molecular perspective by Samira Pourrezaei, Arash Letafati, Ghazale Molaverdi, Mehdi Norouzi, Sayed-Hamidreza Mozhgani

“…The principal aim of this study was to investigate cellular processes related to innate immune response, intracellular protein transport, and translational initiation regulation in individuals afflicted with ATLL and Acute lymphoblastic leukemia (ALL). …”
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Flow cytometry sorting of cells infected with African swine fever virus by A. S. Pershin, I. V. Shevchenko, T. N. Komova, A. Mazloum, N. N. Vlasova, E. O. Morozova, A. S. Igolkin, K. N. Gruzdev

“…The use of attenuated virus variants enables a thorough  investigation of the factors influencing the virulence of African swine fever virus and the immune  response  to it. This involves the use of naturally attenuated virus variants, as well as of the variants attenuated by a long-term passaging of the virus in cell cultures. …”
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A single-cell atlas of the Culex tarsalis midgut during West Nile virus infection. by Emily A Fitzmeyer, Taru S Dutt, Silvain Pinaud, Barb Graham, Emily N Gallichotte, Jessica L Hill, Corey L Campbell, Hunter Ogg, Virginia Howick, Mara K N Lawniczak, Erin Osborne Nishimura, Sarah Hélène Merkling, Marcela Henao-Tamayo, Gregory D Ebel

“…Our findings establish a Cx. tarsalis midgut cell atlas, and provide insight into midgut infection dynamics of WNV by characterizing cell-type specific enhancement/restriction of, and immune response to, infection at the single-cell level.…”
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Immunogenicity and vaccine efficacy of Actinobacillus pleuropneumoniae-derived extracellular vesicles as a novel vaccine candidate by Su Hyun Park, Yun Hye Kim, Hyeon Jin Lee, Jeong Moo Han, Byoung-Joo Seo, Gyeong-Seo Park, Chonghan Kim, Young Bae Ryu, Woo Sik Kim

“…These findings suggest that APP-EVs are promising vaccine candidates, capable of inducing potent APP-specific T-cell responses, particularly Th1, Th17, CTL, and multifunctional T-cells, thereby enhancing the protective immune response against APP infection.…”
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Targeting SLC4A4: A Novel Approach in Colorectal Cancer Drug Repurposing by Krunal Pawar, Pramodkumar P. Gupta, Pooran Singh Solanki, Ravi Ranjan Kumar Niraj, Shanker L. Kothari

“…This study aims to explore the role of the SLC4A4 transporter as a biomarker in CRC progression and its potential as a therapeutic target, particularly in relation to tumor acidity and immune response. Methods: The study utilized computational approaches, including receptor-based virtual screening and high-throughput docking, to identify potential SLC4A4 inhibitors. …”
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Pathogenicity of avian reovirus variant in the immune organs of broiler chicks by Haiyang Yu, Yudong Zhu, Qiong Wu, Wanjun Zhao, You Wang, Dong Wang, Huaguang Lu, Youxiang Diao, Yijing Li, Yi Tang

“…This study provides a rationale for the prevention and control of emerging avian reovirus and adds to the evidence of the effects of ARV on immune organs, with the expectation that it will be useful in understanding the immune response-related aspects of the disease in subsequent studies.…”
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Invariant Natural Killer T Cells as Key Players in Host Resistance against Paracoccidioides brasiliensis by Joes Nogueira-Neto, Flavio V. Loures, Alessandra S. Schanoski, David A. G. Andrade, Michelangelo B. Gonzatti, Tania A. Costa, Bruno C. Vivanco, Patrícia Xander, Daniela S. Rosa, Vera L. G. Calich, Alexandre C. Keller

“…The deficient innate immune response of Jα18-/- mice to Pb18 infection resulted in increased fungal burden in the lungs and spleen. …”
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