Correlation between the Systemic Immunoinflammatory Index and Platelet–Lymphocyte Ratio in Patients with Adenomyosis by Yan Dong, YaHui Chen, YaNan Wang, Lin Wang, Yan Zhou, Mei Xue, Lin Sun

“…The chronic inflammatory immune response is a significant factor in the pathogenesis of benign gynecological diseases. …”
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Multiple Brain Abscesses in a Patient with Myasthenia Gravis – a Case Report by S. Radzevičiūtė, G. Liaudanskytė, I. Baužaitė, N. Balčiūnienė, A. Vaitkus

“…Healthcare providers must maintain a high degree of clinical suspicion for early diagnosis in immunosuppressed patients because of their diminished capacity to generate a typical immune response, which can make typical infection indications less obvious. …”
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Expression and Secretion of CXCL-8 and CXCL-10 From <emph>Mycobacterium Bovis</emph> BCG-Infected Human Epithelial Cells: Role of IL-4

“…Collectively, these data demonstrate that <emph>M. bovis</emph> BCG-infected human epithelial cells can have an active role in a local inflammatory immune response via the secretion of CXC chemokines which can be selectively regulated by Th2-derived cytokines.…”
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The Pathogenesis of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome: A Review of Current Research by Barbara Kraszewska-Głomba, Agnieszka Matkowska-Kocjan, Leszek Szenborn

“…Immunological mechanisms of PFAPA involve an abnormal, IL-1β dependent innate immune response to an environmental trigger, which leads to Th1-driven inflammation expressed by recruitment of T-cells to the periphery.…”
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Targeting fucosyltransferase FUT8 as a prospective therapeutic approach for DLBCL by Hao Xu, Qi Li, Yuchen Zhang, Chuan He, Xinyun Zhang, Zhiming Wang, Meifang Zhao, Yali Chai, Wenzhuo Zhuang, Bingzong Li

“…Additionally, morusinol’s ability to hinder M2-like polarization of tumor-associated macrophages suggested its potential in immune response modulation within DLBCL. Collectively, morusinol showcased substantial promise as an anti-tumor agent for potential clinical application in DLBCL management, potentially augmenting established therapeutic strategies. …”
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Nanoengineering of Phosphate/Phosphonate Drugs via Competitive Replacement with Metal‐Phenolic Networks to Overcome Breast Tumor with Lung and Bone Metastasis by Wanrui Shi, Dashuai Liu, Wenjie Feng, Yang Chen, Yonggang Wang, Zhihong Nie, Yi Liu, Hao Zhang

“…The results demonstrate that, by triggering pyroptosis and activating the cGAS‐STING pathway, the nanodrugs exhibit potent cytotoxicity and accurate selectivity in eradicating orthotopic breast tumors, and activate an antitumor immune response against lung and bone metastases. Because the competitive coordination strategy is applicable to a variety of phosphate/phosphonate agents, it holds significant potential for enhancing the clinical efficacy of phosphate/phosphonate drugs and advancing nanodrug development for complex therapeutic applications.…”
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Effect of Antifungal-Treated Host Macrophages on Candida glabrata by Hong-Bin Li, Na Li, Shu-Ran Wen, Ming-Yue Qiang, Zheng-Hui Yang, Tian-Xiang Dong, Yu-Ye Li, Yi-Qun Kuang

“…Echinocandins may increase their antifungal efficacy by altering the innate immune response of macrophages and attenuating antioxidants of this organism.…”
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Prolonged Helium Postconditioning Protocols during Early Reperfusion Do Not Induce Cardioprotection in the Rat Heart In Vivo: Role of Inflammatory Cytokines by Gezina Tanya Mei Ling Oei, Hamid Aslami, Raphaela Priscilla Kerindongo, Renske Johanna Steenstra, Charlotte Jacqueline Peter Beurskens, Anita Maria Tuip-de Boer, Nicole Petra Juffermans, Markus Werner Hollmann, Benedikt Preckel, Nina Claudia Weber

“…Effects of helium postconditioning protocols on infarct size and the ischemia/reperfusion-induced immune response were investigated by measurement of protein and mRNA levels of proinflammatory cytokines. …”
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Brucella osteoarthritis: recent progress and future directions by Jinlei Chen, Jinlei Chen, Jinlei Chen, Jinlei Chen, Jinlei Chen, Feijie Zhi, Feijie Zhi, Feijie Zhi, Guanghai Zhao, Guanghai Zhao, Mengru Su, Mengru Su, Mengru Su, Hao Geng, Hao Geng, Hao Geng, Wei Song, Wei Song, Yuefeng Chu, Yuefeng Chu, Yuefeng Chu, Haihong Zhang, Haihong Zhang

“…Brucella grows and multiplies in intrinsic cells of the skeleton, including osteoblasts, osteocyte and osteoclasts, which results in sustained release of bacteria that leads to exacerbation of the immune response. Concurrently, activation of the immune system caused by invasion with Brucella may affect the dynamic balance of the skeleton. …”
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Tumor microenvironment–responsive and modulatory manganese-based nanoenzyme for enhanced tumor immunotherapy by Qi Yang, Qiong Wu, Haiyan Liu, Jiandong Wu, Feng Ma, Xiaofeng Tian

“…Besides the photothermal effect and the enhancement of ROS burst-induced immunogenic cell death, combination of Mn2+ released from Mn-based nanoenzyme in acidic TME and programmed death-ligand 1 blockade triggered a significant anti-tumor immune response. A remarkable in vivo synergistic therapeutic effect was achieved with effective inhibition of primary tumor growth and lung metastasis. …”
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A Multifunctional Cobalt‐Containing Implant for Treating Biofilm Infections and Promoting Osteointegration in Infected Bone Defects Through Macrophage‐Mediated Immunomodulation by Nongyang Yan, Hao Zhou, Penghe Jin, Tengfei Li, Qi Liu, Hao Ning, Zhixin Ma, Linfei Feng, Tao Jin, Youwen Deng, Zhengwei Wu

“…The optimal treatment strategy combines immune response modification to promote osteogenesis with effective bacterial infection removal that does not require long‐term antibiotic use. …”
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Oral probiotic extracellular vesicle therapy mitigates Influenza A Virus infection via blunting IL-17 signaling by Hongxia Zhou, Wenbo Huang, Jieting Li, Peier Chen, Lihan Shen, Wenjing Huang, Kailin Mai, Heyan Zou, Xueqin Shi, Yunceng Weng, Yuhua Liu, Zifeng Yang, Caiwen Ou

“…Extracellular vesicles (EVs) derived from probiotics have emerged as potential mediators of host immune response and anti-inflammatory effect. However, the specific anti-inflammatory effects and underlying mechanisms of probiotics-derived EVs on IAV remain unclear. …”
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Systemic and immunotoxicity induced by topical application of perfluoroheptane sulfonic acid (PFHpS) or perfluorooctane sulfonic acid (PFOS) in a murine model by Lisa M. Weatherly, Hillary L. Shane, Laurel G. Jackson, Ewa Lukomska, Rachel Baur, Madison P. Cooper, Stacey E. Anderson

“…Additionally, PFHpS significantly reduced the humoral immune response and altered immune subsets in the spleen, suggesting immunosuppression. …”
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Hyperuricemia-induced complications: dysfunctional macrophages serve as a potential bridge by Wenyi Gu, Wenyi Gu, Jiajing Zhao, Yu Xu, Yu Xu, Yu Xu

“…As HUA is a metabolic syndrome, the immune response is likely to play an active role throughout the whole process. …”
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Identification of early prediction biomarkers of severity in patients with severe fever with thrombocytopenia syndrome based on plasma proteomics by Qian Zhang, Qian Zhang, Zhengyi Jiang, Nan Jiang, Luchen Shi, Jiaying Zhao, Jie Zhao, Jie Zhao, Ke Ouyang, Ke Ouyang, Huaying Huang, Huaying Huang, Yaqin Zhang, Yan Dai, Nannan Hu, Ping Shi, Yaping Han, Ke Jin, Jun Li

“…A cohort consisting of 190 patients with SFTS was used to develop the predictive model for severe illness and subsequently validate it in a new cohort consisting of 93 patients with SFTS.ResultsA significant increase in plasma proteins associated with various functional clusters, such as the proteasomal protein catabolic process, phagocytosis, and humoral immune response, was observed in severe SFTS patients. …”
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Blood Morphology and Hematology of Adult Baikal Seals (<i>Pusa sibirica</i> Gmelin, 1788) Under Professional Care by Polina Esipova, Irina Suvorova, Veronika Yachmen, Igor Pushchin

“…The results could be useful for Baikal seal veterinary care, immune response research, and comparative studies with other pinnipeds.…”
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Stress Hyperglycemia, Insulin Treatment, and Innate Immune Cells by Fangming Xiu, Mile Stanojcic, Li Diao, Marc G. Jeschke

“…Along with others, we hypothesize that reduction in morbidity and mortality observed in patients receiving insulin treatment is partially due to its effect on the attenuation of the immune response. However, there still remains substantial controversy regarding moderate versus intensive insulin treatment. …”
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Immunological Impacts of Diabetes on the Susceptibility of Mycobacterium tuberculosis by Birhanu Ayelign, Markos Negash, Meaza Genetu, Tadelo Wondmagegn, Tewodros Shibabaw

“…In addition, impaired immune response and killing of intracellular bacteria potentially increase bacterial load, chronic inflammation, and central necrosis that facilitate bacterial dissemination and miliary tuberculosis. …”
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Inter- Not Intraindividual Differences in sTWEAK Levels Predict Functional Deterioration and Mortality in Patients with Dilated Cardiomyopathy by Kai-Uwe Jarr, Manfred Nelles, Hugo A. Katus, Emmanuel Chorianopoulos

“…Further research will be necessary to elucidate the exact role of sTWEAK as a potential modulator of immune response in the setting of dilated cardiomyopathy.…”
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A covalent peptide-based lysosome-targeting protein degradation platform for cancer immunotherapy by Youmei Xiao, Zhuoying He, Wanqiong Li, Danhong Chen, Xiaoshuang Niu, Xin Yang, Wenxuan Zeng, Mengfan Wang, Yuzhen Qian, Ye Su, Feiyu Luo, Guanyu Chen, Juan Liu, Xinghua Sui, Xiuman Zhou, Yanfeng Gao

“…Furthermore, both in anti-PD-1-responsive and -resistant tumor models, the Pep-TACs exert significant anti-tumor immune response. It is noteworthy that Pep-TACs can cross the BBB and prolong the survival of mice with in situ brain tumor. …”
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