Vitamin D Receptor Gene Polymorphisms Influence T1D Susceptibility among Pakistanis by Maryam Mukhtar, Andleeb Batool, Abdul Wajid, Iram Qayyum

“…The vitamin D receptor (VDR) gene regulates insulin secretion from the pancreas and acts as a mediator of the immune response through vitamin D. Polymorphism in VDR causes alterations in the functioning of vitamin D, leading to type 1 diabetes (T1D) predisposition. …”
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BNT162b2 Vaccination during Pregnancy Protects Both the Mother and Infant: Anti-SARS-CoV-2 S Antibodies Persistently Positive in an Infant at 6 Months of Age by Chetna Mangat, Natasa Milosavljevic

“…This is the first case report in which BNT162b2 vaccination during pregnancy yielded a persistent immune response in an infant at 6 months of age. The declining anti-SARS-CoV-2 S antibody titers noted at 6 months of age emphasize the need for the vaccination of children at this age.…”
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Impacts of host phylogeny, diet, and geography on the gut microbiome of rodents. by Sufia Akter Neha, John D Hanson, Jeremy E Wilkinson, Robert D Bradley, Caleb D Phillips

“…Mammalian gut microbial communities are thought to play a variety of important roles in health and fitness, including digestion, metabolism, nutrition, immune response, behavior, and pathogen protection. Gut microbiota diversity among hosts is strongly shaped by diet as well as phylogenetic relationships among hosts. …”
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Anaesthesia affects immune function and impact on long-term cancer prognosis: A review by Kisdyanti Yuniar Melissa, Suandika Made, Rahmawati Arni Nur

“…Anaesthetic procedures, which are essential in surgical management, can affect the body’s immune response through direct and indirect mechanisms. …”
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Radiotherapy for Melanoma: More than DNA Damage by Susanne J. Rogers, Emsad Puric, Brigitte Eberle, Niloy R. Datta, Stephan B. Bodis

“…It has long been known that radiation causes not only DNA strand breaks, apoptosis, and necrosis, but also immunogenic modulation and cell death through the induction of dendritic cells, cell adhesion molecules, death receptors, and tumour-associated antigens, effectively transforming the tumour into an individualised vaccine. This immune response can be enhanced by the application of clinical hyperthermia as evidenced by randomised trial data in patients with melanoma. …”
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Correlation between Serum Osteopontin and miR-181a Levels in Allergic Rhinitis Children by Wenlong Liu, Qingxiang Zeng, Renzhong Luo

“…This study aims to evaluate the expression of OPN and miR-181a in children with AR and their association with Th1/Th2 immune response. Methods. Children who suffered from AR were included along with control subjects. …”
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Association of CD24, CD27, and co-stimulatory molecules CD80 immunological marker expression on B-cells of human peripheral blood with development of celiac disease by Rahab Abd-Ali Al-Madany, Noor Abdulameer Oudah

“…CONCLUSION: These findings suggest that numerical deficiency of CD24, CD27, and CD80 expression on B-cells in the peripheral blood mononuclear cell population, that may involve the loss of auto-tolerance that plays an important role in the immune response associated with inflammation and tissue damage in celiac disease. …”
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Exclusive Cutaneous and Subcutaneous Sarcoidal Granulomatous Inflammation due to Immune Checkpoint Inhibitors: Report of Two Cases with Unusual Manifestations and Review of the Lit... by Narciss Mobini, Rummit Dhillon, Jason Dickey, Jordan Spoon, Kaviyon Sadrolashrafi

“…The primary target antigens are cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4), a downregulator of T-cell activation, and programmed cell death-1 receptor (PD-1), a regulator of T-cell proliferation. This enhanced immune response can induce autoimmune adverse effects in many organs. …”
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Alterations of the Gut Microbiome in Chinese Zhuang Ethnic Patients with Sepsis by Jieyang Yu, Hongping Li, Jingjie Zhao, Yanhua Huang, Chunlei Liu, Pengfei Yang, Dinggui Lu, Jian Song, Lingzhang Meng

“…Sepsis is characterized as a dysregulated host immune response to infection and has been known to be closely associated with the gut microbiome. …”
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Elevated Circulating IL-1<mml:math> <mml:mi>&#x03B2;</mml:mi> </mml:math> and TNF-Alpha, and Unaltered IL-6 in First-Trimester Pregnancies Complicated by Threatened Abortion With...

“…It is concluded that in first-trimester TACP with adverse outcome, a distinct immune response, as reflected by elevated maternal IL-1<mml:math> <mml:mi>&#x03B2;</mml:mi> </mml:math>, TNF-alpha, and unaltered IL-6 levels, is relevant to a negative obstetric outcome.…”
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Identification of Molecular Subtypes and Prognostic Features of Breast Cancer Based on TGF-β Signaling-related Genes by Jia Qu, Mei-Huan Wang, Yue-Hua Gao, Hua-Wei Zhang

“…Additionally, an unsupervised clustering algorithm was applied to categorize BC patients into two distinct groups based on the five TSRGs, with a focus on immune response and overall survival (OS). Further investigations were conducted to explore variations in pharmacotherapy and the tumor microenvironment across different patient cohorts and clusters. …”
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Cryptosporidiosis in a Zoonotic Gastrointestinal Disorder Perspective by Thivya Balendran, Devika Iddawela, Sajanee Lenadora

“…Therefore, with the objective of providing an in-depth analysis of Cryptosporidiosis in immunocompromised patients, this review presents a comprehensive understating of the prevalence, risk factors, pathophysiology of Cryptosporidium infection, clinical presentation in the immunocompromised, the immune response of the host, diagnostic methods performed in laboratory settings, possible treatments, and prevention methods, which can be used for further studies. …”
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The Role of TLR4 on B Cell Activation and Anti-β2GPI Antibody Production in the Antiphospholipid Syndrome by Si Cheng, Haibo Wang, Hong Zhou

“…In this paper, we aim to review the functions of TLR4 in B cell immune response and antibody production in autoimmune disease APS and try to find a new way for the prevention and treatment of APS.…”
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The Immunological Plasmodium falciparum Malaria Characteristics of Children in Tajikistan Republic by Nighina M. Khodzhaeva, Alla M. Baranova, Anatoly K. Tokmalaev

“…The imbalance of cytokine profile is an important pathogenic factor in the development of severe and recurrent forms of the disease, since the formation of a defective immune response to parasitic antigens contributes to adverse outcomes. …”
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Effect of innate and induced immunity on infectious bursal disease pathogenesis by A. N. Semina

“…Recent studies, however, demonstrated the role of the enhanced immune response at early stage of the infection along with increased production of cytokine storm-inducing promediators. …”
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Immunoprotective Effect of Seabuckthorn (Hippophae rhamnoides) and Glucomannan on T-2 Toxin-Induced Immunodepression in Poultry by T. Ramasamy, C. Varshneya, V. C. Katoch

“…A significant (P<.05) increase in DTH reaction and non-specific immune response was seen in seabuckthorn and glucomannan fed birds. …”
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Diagnosis of bovine viral diarrhea in Bubalus bubalis dairy farms by Oriana Gavidia, Rosaura Pérez-Gil

“…These results show a humoral immune response against potential BVD infections (regardless of the milk yield) since p80 is a non-structural protein that manifests during viral replication. …”
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Density of Langerhans Cells in Nonmelanoma Skin Cancers: A Systematic Review by Joanna Pogorzelska-Dyrbuś, Jacek C. Szepietowski

“…We hypothesise that as there is a high inconsistency between the results of the studies, as far as the densities of LCs observed in the specimens are concerned, it seems that the mechanism of the influence of LCs on the antitumoural immune response is complicated. Finally, as at present, there is a paucity of available risk scores for the recurrence or progression of BCC or SCC, the creation of classification stratifying that risk including the density of LCs could bring additional information both for the physician and the patient.…”
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Mesenchymal Stem Cell Therapy for Cardiac Inflammation: Immunomodulatory Properties and the Influence of Toll-Like Receptors by F. van den Akker, S. C. A. de Jager, J. P. G. Sluijter

“…As MSC are potent modulators of the immune system, this could influence this postinfarct immune response. Since MSC express toll-like receptors (TLR), danger signal (DAMP) produced after MI could influence their immunomodulatory properties. …”
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Trichosanthes kirilowii Maxim. Polysaccharide attenuates diabetes through the synergistic impact of lipid metabolism and modulating gut microbiota by Qiaoying Song, Kunpeng Zhang, Shuyan Li, Shaoting Weng

“…The results showed that high-fat diet significantly increased the oral glucose tolerance test (OGTT), viscera index, oxidative stress, impaired glucose tolerance, decreased body weight, immune response and short-chain fatty acid (SCFAs) content, and disrupted the balance of intestinal flora structure. …”
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