The Development of a Novel Broad-Spectrum Influenza Polypeptide Vaccine Based on Multi-Epitope Tandem Sequences by Song Zhao, Junhao Luo, Wenhui Guo, Li Li, Siyu Pu, Libo Dong, Wenfei Zhu, Rongbao Gao

“…Background: Polypeptide vaccines have the potential to improve immune responses by targeting conserved and weakly immunogenic regions in antigens. …”
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BAFF and APRIL immunotherapy following Bacille Calmette-Guérin vaccination enhances protection against pulmonary tuberculosis in mice by Min Xie, Chen-Yu Tsai, Joshua Woo, Frank Nuritdinov, Melissa Cristaldo, Narineh M. Odjourian, Rosleine Antilus-Sainte, Maureen Dougher, Martin Gengenbacher, Martin Gengenbacher

“…Administered at birth, BCG induces broad immune responses against a large number of antigens shared with Mycobacterium tuberculosis (Mtb), but protection wanes over time. …”
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Cytokines in Thyroid-Associated Ophthalmopathy by Pengbo Zhang, Huang Zhu

“…In recent years, cytokines and the immune responses they mediate have been crucial in disease progression, and currently, common evidence has shown that drugs targeting cytokines, such as tocilizumab, infliximab, and adalimumab, may be novel targets for therapy. …”
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Platelet‐activating factor: a potential therapeutic target to improve cancer immunotherapy by Qi Yan, Hemn Mohammadpour

“…The tumor microenvironment (TME) fosters cancer progression by supporting the differentiation and proliferation of myeloid‐derived suppressor cells (MDSCs), which play a critical role in suppressing immune responses and facilitating tumor growth. Recent findings by Dahal et al. reveal that platelet‐activating factor (PAF), a lipid mediator elevated in the TME, contributes to the differentiation of neutrophils into immunosuppressive neutrophils. …”
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Antibody-Dependent Cellular Cytotoxicity and NK Cell-Driven Immune Escape in HIV Infection: Implications for HIV Vaccine Development by Gamze Isitman, Ivan Stratov, Stephen J. Kent

“…There is an opportunity to harness these immune responses in the design of more effective HIV vaccines.…”
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Autologous Platelet Rich Plasma (PRP) — A Treatment Modality of Neuropathic Ulcers in Leprosy Patients: An Interventional Study by Tejinder Kaur, Sahibpreet Kaur, Gurkim Kaur

“…Use of Autologous platelet-rich plasma (PRP) in trophic ulcers is known to facilitate the restoration of metabolic processes, promotion of neo-angiogenesis, improvement of cellular metabolism, and activation of local immune responses. Our case series of 10 leprosy patients aimed to assess the efficacy and safety of PRP in healing trophic ulcers among leprosy patients. …”
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Innate Lymphoid Cells: Regulators of Gut Barrier Function and Immune Homeostasis by Hui Fan, Aiyun Wang, Yuan Wang, Ye Sun, Jing Han, Wenxing Chen, Shijun Wang, Yuanyuan Wu, Yin Lu

“…Innate lymphoid cells (ILCs), identified in the early years of this century as a new class of leukocyte family unlike the B or T lymphocytes, play a unique role bridging the innate and adaptive immune responses in mucosal immunity. Their origin, differentiation, and activation process and functions have caught global interest. …”
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Immune Evasion Strategies of Pre-Erythrocytic Malaria Parasites by Hong Zheng, Zhangping Tan, Wenyue Xu

“…Although the robust host immune responses limit the development of the liver stage, malaria parasites have also evolved strategies to suppress host defenses at the pre-erythrocytic stage. …”
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Insights into the Roles of B Cells in Patients with Sepsis by Xijie Dong, Hao Tu, Shuang Qin, Xiangjun Bai, Fan Yang, Zhanfei Li

“…Sepsis-related deaths primarily occur during immunosuppression; the disease can hamper the numbers and function of B cells, which mediate innate and adaptive immune responses to maintain immune homeostasis. Dysfunction of B cells, along with aggravated immunosuppression, are closely related to poor prognosis. …”
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The Impact of the Myeloid Response to Radiation Therapy by Michael J. Gough, Kristina Young, Marka Crittenden

“…We discuss how radiation therapy similarly triggers inflammation followed by repair, the consequences to adaptive immune responses in the treatment site, and how the myeloid response to radiation may impact immunotherapies designed to improve control of residual cancer cells.…”
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Probiotics for Alleviating Alcoholic Liver Injury by Zelin Gu, Yanlong Liu, Shumeng Hu, Ying You, Jiaqi Wen, Wancong Li, Yuhua Wang

“…Probiotics enhance immune responses and reduce the levels of alcohol-induced inflammatory cytokines and reactive oxygen species (ROS) production in the liver and intestine. …”
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Primary Atopic Disorders: Expanding Field of Inborn Errors of Immunity by Güzin Özçifci, Sena Nur Arbağ, Yasemin Kendir-Demirkol, Joshua D Milner

“…Liable genetic alterations lead to signaling pathways and cellular functioning changes, which skew to type-2 immune responses. Elucidation of these pathways and identifying these disorders have the utmost importance, since early identification of some of these disorders significantly changes the prognosis and targeted treatments offer improved outcomes. …”
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T-regulatory cells for the treatment of autoimmune diseases by Marina S. Fisher, Marina S. Fisher, Sergey V. Sennikov, Sergey V. Sennikov

“…T-regulatory cells (Treg) are key factors in the formation of immune tolerance. Tregs modulate immune responses and repair processes, controlling the innate and adaptive immune system. …”
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Effects of vegetarian diet-associated nutrients on gut microbiota and intestinal physiology by Wei Xiao, Qingsong Zhang, Leilei Yu, Fengwei Tian, Wei Chen, Qixiao Zhai

“…In addition, microbe-derived metabolites of specific nutrients known to be abundant in vegetarian diets (such as indigestible carbohydrates, arginine, and others) are important to promote effective intestinal immune responses, maintain intestinal barrier function, and protect against pathogens. …”
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Polymer-based antimicrobial strategies for periodontitis by Jiajia Chen, Shujun Dong

“…Periodontitis is a chronic inflammatory condition driven by plaque-associated microorganisms, where uncontrolled bacterial invasion and proliferation impair host immune responses, leading to localized periodontal tissue inflammation and bone destruction. …”
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Virotherapy in Head and Neck Cancer by Zhan Wang

“…The primary focus of virotherapy is to exploit the inherent properties of viruses to infect and replicate within cancer cells, triggering immune responses and promoting anti-tumor effects. Notably, oncolytic virotherapy, viral vector-based vaccines, and viral vector-based gene therapy are key branches of virotherapeutic interventions that have demonstrated potential in preclinical and clinical studies.…”
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CD40 Ligand Potentiates Immunogenecity of <i>Mycoplasma pneumoniae</i> Subunit Vaccine Candidate in a Murine Model by Jinqi Shu, Gaojian Li, Jianhong Shu, Huapeng Feng, Yulong He

“…This study provides clear evidence that CD40L potentiates the humoral and cellular immune responses to the Mhp chimeric protein P97R1P46P42 in the mouse model. …”
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Microencapsulation of probiotics and its applications with prebiotic in Pacific white shrimp larvae through Artemia sp. by Dian Eka Ramadhani, Widanarni Widanarni, Sukenda Sukenda

“…., on bacterial population, growth performances, immune responses, and disease resistance of Pacific white shrimp larvae. …”
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The Confluence of Stereotactic Ablative Radiotherapy and Tumor Immunology by Steven Eric Finkelstein, Robert Timmerman, William H. McBride, Dörthe Schaue, Sarah E. Hoffe, Constantine A. Mantz, George D. Wilson

“…Herein, we will discuss how SABR can induce cellular expression of MHC I, adhesion molecules, costimulatory molecules, heat shock proteins, inflammatory mediators, immunomodulatory cytokines, and death receptors to enhance antitumor immune responses.…”
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Desensitization of delayed-type hypersensitivity in mice: suppressive environment by Takashi Katsura, Kazuo Kobayashi, Michio Hosaka, Sachiko Sugihara, Tsuyoshi Kasama, Keita Kasahara, Stanley Cohen, Takeshi Yoshida

“…The systemic injection of high doses of antigen into a preimmunized animal results in transient unresponsiveness of cell-mediated immune responses. This phenomenon is known as desensitization. …”
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