Impact of Metabolic States on SARS-CoV-2 Vaccine Responses in Mouse Models of Obesity and Diabetes by Olivia A. Smith, Brent Fujimoto, Teri Ann S. Wong, Albert To, Troy Odo, Aquena Ball, Brien K. Haun, Hiromi Muramatsu, Ying K Tam, Norbert Pardi, Axel T. Lehrer

“…In this study, we investigated the immune responses generated by various SARS-CoV-2 vaccine platforms in mouse models with obesity and diabetes, focusing on both cell-mediated and humoral immune responses. …”
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Interferons and Interferon Regulatory Factors in Malaria by Sin Yee Gun, Carla Claser, Kevin Shyong Wei Tan, Laurent Rénia

“…Acquired adaptive immune responses control parasite replication and infection-induced pathologies. …”
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Impact of COVID-19 on Ocular Surface Health: Infection Mechanisms, Immune Modulation, and Inflammatory Responses by Duliurui Huang, Weixia Xuan, Zhijie Li

“…Additionally, the interplay between systemic and ocular immune responses is highlighted, analyzing how systemic COVID-19 inflammation influences ocular surface health. …”
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Enter the Matrix: Fibroblast-immune cell interactions shape extracellular matrix deposition in health and disease. [version 2; peer review: 1 approved, 2 approved with reservations... by Anthony Altieri, Grace V. Visser, Matthew B. Buechler

“…Fibroblasts can directly and indirectly regulate immune responses by secreting ECM and ECM-bound molecules to shape tissue structure and influence organ function. …”
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Ex Vivo Restimulation of Human PBMC Expands a CD3+CD4-CD8-γδ+ T Cell Population That Can Confound the Evaluation of CD4 and CD8 T Cell Responses to Vaccination by B. J. Sedgmen, L. Papalia, L. Wang, A. R. Dyson, H. A. McCallum, C. M. Simson, M. J. Pearse, E. Maraskovsky, D. Hung, P. P. Eomois, G. Hartel, M. J. Barnden, S. P. Rockman

“…The measurement of vaccine-induced humoral and CD4+ and CD8+ cellular immune responses represents an important correlate of vaccine efficacy. …”
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Cross-protection against homo and heterologous influenza viruses via intranasal administration of an HA chimeric multiepitope nanoparticle vaccine by Yongqiang Zhao, Jia Liu, Chun Peng, Shuangshuang Guo, Bo Wang, Longping Chen, Yating Wang, Haiwen Tang, Liming Liu, Qi Pan, Shiren Li, Jingyu Wang, Dongni Yang, Enqi Du

“…However, seasonal influenza vaccines often elicit strain-specific immune responses and confer little protection against mismatched strains. …”
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Developing anti-TDE vaccine for sensitizing cancer cells to treatment and metastasis control by Stephene S. Meena, Benson K. Kosgei, Geofrey F. Soko, Cheng Tingjun, Ramadhani Chambuso, Julius Mwaiselage, Ray P. S. Han

“…TDEs support cancer progression by suppressing anti-tumor immune responses, promoting metastasis, and conferring drug resistance. …”
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Programmed Cell Death Pathways in the Pathogenesis of Systemic Lupus Erythematosus by Fangyuan Yang, Yi He, Zeqing Zhai, Erwei Sun

“…Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by excessive inflammatory and immune responses and tissue damage. Increasing evidence has demonstrated the important role of programmed cell death in SLE pathogenesis. …”
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Oxidative Stress in Cardiovascular Inflammation: Its Involvement in Autoimmune Responses by Elisabetta Profumo, Brigitta Buttari, Rachele Riganò

“…Different self-antigens or modified self-molecules have been identified as target of humoral and cellular immune responses in patients with atherosclerotic disease. …”
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The Role of Toll-Like Receptor Signaling in the Progression of Heart Failure by Lili Yu, Zhiwei Feng

“…Elevated levels of inflammatory mediators have been identified in patients with HF, which are primarily manifestations of innate immune responses mediated by pattern recognition receptors (PRRs). …”
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Dose-dependent serological profiling of AdCLD-CoV19-1 vaccine in adults by Jung Hyuk Lee, Yuna Shin, Kwang-Soo Shin, Ju Yeon Park, Mi Sun Kim, Young-Shin Park, Wuhyun Kim, Joon Young Song, Ji Yun Noh, Hee Jin Cheong, Chang-Yuil Kang, Sang Hwan Seo, Jae-Ouk Kim, Deok Ryun Kim, Nathaniel S. Hwang, Jae Seung Yang, Jerome H. Kim, Byoung-Shik Shim, Manki Song

“…In this study, we conducted a systems serology analysis to investigate changes in humoral immune responses induced by varying doses of the AdCLD-CoV19-1 vaccine in a phase I clinical trial. …”
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Deubiquitinase Ubp5 is essential for pulmonary immune evasion and hematogenous dissemination of Cryptococcus neoformans by Guizhen Wang, Yan Liu, Qianyu Li, Changhui Wang, Wei Fang

“…Attenuated virulence is closely associated with enhanced host immune responses, rather than diminished pathogen fitness alone. …”
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Vascularized Composite Allograft Rejection Is Delayed by Intrajejunal Treatment with Donor Splenocytes without Concomitant Immunosuppressants by Christopher Glenn Wallace, Chia-Hung Yen, Hsiang-Chen Yang, Chun-Yen Lin, Ren-Chin Wu, Wei-Chao Huang, Jeng-Yee Lin, Fu-Chan Wei

“…Recipients’ immune responses were assessed by mixed lymphocyte reaction (MLR) against donor antigen and controls. …”
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Macrophages in sepsis-induced acute lung injury: exosomal modulation and therapeutic potential by Kaiying Lv, Qun Liang

“…Macrophages, key modulators of immune responses, play a dual role in both promoting and resolving inflammation. …”
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Regulation of Immune Function by Polyphenols by Sujuan Ding, Hongmei Jiang, Jun Fang

“…In summary, polyphenols can be used to regulate intestinal mucosal immune responses, allergic diseases, and antitumour immunity.…”
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Mycobacterium ulcerans and Mycobacterium marinum: Pathogenesis, Diagnosis and Treatment by Loh Teng-Hern Tan, Pendru Raghunath, Long Chiau Ming, Jodi Woan-Fei Law

“…Meanwhile, like most pathogenic mycobacteria, M. marinum evades the host immune responses by invading and replicating inside host cells and it is capable of modulating host immune responses. …”
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Toll-Like Receptor 2 as a Regulator of Oral Tolerance in the Gastrointestinal Tract by Matthew C. Tunis, Jean S. Marshall

“…Food allergy, other adverse immune responses to foods, inflammatory bowel disease, and eosinophilic esophagitis have become increasingly common in the last 30 years. …”
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Advancing veterinary vaccines design through trained immunity insights by Xin Wang, Xin Wang, Xin Wang, Xin Wang, Guohua Yu, Guohua Yu, Guohua Yu

“…We analyze key molecular mechanisms, including the shift to aerobic glycolysis and sustained epigenetic changes, that enable enhanced immune responses. Strategic approaches for vaccine optimization are proposed, focusing on selecting effective trained immunity inducers, developing innovative adjuvant systems, and achieving synergistic enhancement of immune responses. …”
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Application of IgG-Derived Natural Treg Epitopes (IgG Tregitopes) to Antigen-Specific Tolerance Induction in a Murine Model of Type 1 Diabetes by Leslie P. Cousens, Yan Su, Elizabeth McClaine, Xin Li, Frances Terry, Robert Smith, Jinhee Lee, William Martin, David W. Scott, Anne S. De Groot

“…HLA class II-restricted regulatory T cell (Treg) epitopes in IgG (also called “Tregitopes”) have been reported to suppress immune responses to coadministered antigens by stimulating the expansion of natural Tregs (nTregs). …”
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A Danger-Theory-Based Immune Network Optimization Algorithm by Ruirui Zhang, Tao Li, Xin Xiao, Yuanquan Shi

“…The danger theory emphasizes that danger signals generated from changes of environments will guide different levels of immune responses, and the areas around danger signals are called danger zones. …”
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