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1041
Targeting T-Cell Activation for Malaria Immunotherapy: Scoping Review
Published 2025-01-01“…Immunotherapy, which enhances the immune response and promotes durable T cell activity, offers a promising avenue for more effective and lasting malaria treatments. …”
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1042
Methylation Marks of Blood Leukocytes of Native Hucul Mares Differentiated in Age
Published 2019-01-01“…Genes colocated with age-related differentially methylated regions (age DMRs) are the members of pathways involved in cellular signal transduction, immune response, neurogenesis, differentiation, development, and cancer progression. …”
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1043
Serum Calprotectin: An Antimicrobial Peptide as a New Marker For the Diagnosis of Sepsis in Very Low Birth Weight Newborns
Published 2011-01-01“…To determine the diagnostic utility of serum calprotectin, a mediator of innate immune response against infections, we performed a multicenter study involving newborns with a birth weight <1500 g and a postnatal age >72 hours of life. …”
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1044
Density of Langerhans Cells in Nonmelanoma Skin Cancers: A Systematic Review
Published 2020-01-01“…We hypothesise that as there is a high inconsistency between the results of the studies, as far as the densities of LCs observed in the specimens are concerned, it seems that the mechanism of the influence of LCs on the antitumoural immune response is complicated. Finally, as at present, there is a paucity of available risk scores for the recurrence or progression of BCC or SCC, the creation of classification stratifying that risk including the density of LCs could bring additional information both for the physician and the patient.…”
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1045
Mesenchymal Stem Cell Therapy for Cardiac Inflammation: Immunomodulatory Properties and the Influence of Toll-Like Receptors
Published 2013-01-01“…As MSC are potent modulators of the immune system, this could influence this postinfarct immune response. Since MSC express toll-like receptors (TLR), danger signal (DAMP) produced after MI could influence their immunomodulatory properties. …”
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1046
Insulin Resistance, Inflammation, and Obesity: Role of Monocyte Chemoattractant Protein-1 (orCCL2) in the Regulation of Metabolism
Published 2010-01-01“…To maintain homeostasis under diverse metabolic conditions, it is necessary to coordinate nutrient-sensing pathways with the immune response. This coordination requires a complex relationship between cells, hormones, and cytokines in which inflammatory and metabolic pathways are convergent at multiple levels. …”
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1047
Neutrophil Extracellular Traps (NETs) and Damage-Associated Molecular Patterns (DAMPs): Two Potential Targets for COVID-19 Treatment
Published 2020-01-01“…The persistent excessive inflammatory response can build up a clinical picture that is very difficult to manage and potentially fatal. Modulating the immune response plays a key role in fighting the disease. …”
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1048
Trichosanthes kirilowii Maxim. Polysaccharide attenuates diabetes through the synergistic impact of lipid metabolism and modulating gut microbiota
Published 2025-01-01“…The results showed that high-fat diet significantly increased the oral glucose tolerance test (OGTT), viscera index, oxidative stress, impaired glucose tolerance, decreased body weight, immune response and short-chain fatty acid (SCFAs) content, and disrupted the balance of intestinal flora structure. …”
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1049
Central Role of Gimap5 in Maintaining Peripheral Tolerance and T Cell Homeostasis in the Gut
Published 2015-01-01“…Inflammatory bowel disease (IBD) including Crohn’s disease and ulcerative colitis is often precipitated by an abnormal immune response to microbiota due to host genetic aberrancies. …”
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1050
Macrophages in Tumor Microenvironments and the Progression of Tumors
Published 2012-01-01“…Macrophages are widely distributed innate immune cells that play indispensable roles in the innate and adaptive immune response to pathogens and in-tissue homeostasis. …”
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1051
HCV Proteins and Immunoglobulin Variable Gene (IgV) Subfamilies in HCV-Induced Type II Mixed Cryoglobulinemia: A Concurrent Pathogenetic Role
Published 2012-01-01“…The association between hepatitis C virus (HCV) infection and type II mixed cryoglobulinemia (MCII) is well established, but the role played by distinct HCV proteins and by specific components of the anti-HCV humoral immune response remains to be clearly defined. It is widely accepted that HCV drives the expansion of few B-cell clones expressing a restricted pool of selected immunoglobulin variable (IgV) gene subfamilies frequently endowed with rheumatoid factor (RF) activity. …”
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1052
A bibliometric and visualized analysis of heartland virus
Published 2025-01-01“…Currently, researchers are focusing on pathogenesis, immune response, vector relationships, and epidemiology, providing valuable insights for future studies.…”
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1053
Correlation between the Systemic Immunoinflammatory Index and Platelet–Lymphocyte Ratio in Patients with Adenomyosis
Published 2024-01-01“…The chronic inflammatory immune response is a significant factor in the pathogenesis of benign gynecological diseases. …”
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1054
Multiple Brain Abscesses in a Patient with Myasthenia Gravis – a Case Report
Published 2023-12-01“…Healthcare providers must maintain a high degree of clinical suspicion for early diagnosis in immunosuppressed patients because of their diminished capacity to generate a typical immune response, which can make typical infection indications less obvious. …”
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1055
Evaluation of Oxidative Stress and Mitophagy during Adipogenic Differentiation of Adipose-Derived Stem Cells Isolated from Equine Metabolic Syndrome (EMS) Horses
Published 2018-01-01“…Mesenchymal stem cells (MSCs) are frequently used in both human and veterinary medicine because their unique properties, such as modulating the immune response and differentiating into multiple lineages, make them a valuable tool in cell-based therapies. …”
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1056
Expression and Secretion of CXCL-8 and CXCL-10 From <emph>Mycobacterium Bovis</emph> BCG-Infected Human Epithelial Cells: Role of IL-4
Published 2006-01-01“…Collectively, these data demonstrate that <emph>M. bovis</emph> BCG-infected human epithelial cells can have an active role in a local inflammatory immune response via the secretion of CXC chemokines which can be selectively regulated by Th2-derived cytokines.…”
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1057
Transcriptome Analysis of the Thymus in Short-Term Calorie-Restricted Mice Using RNA-seq
Published 2018-01-01“…Calorie restriction (CR), which is a factor that expands lifespan and an important player in immune response, is an effective protective method against cancer development. …”
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1058
The Pathogenesis of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome: A Review of Current Research
Published 2015-01-01“…Immunological mechanisms of PFAPA involve an abnormal, IL-1β dependent innate immune response to an environmental trigger, which leads to Th1-driven inflammation expressed by recruitment of T-cells to the periphery.…”
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1059
ROLE OF POLYMORPHISM FOR THE PANE1 GENE IN THE FORMATION OF REPRODUCTIVE INDICES IN PIGS
Published 2015-01-01“…Therefore, artificial selection of farm animals for reproductive indices may be accompanied by reduced immune response. Formerly, a single-nucleotide polymorphism in the PANE1 gene for a minor histocompatibility antigen was demonstrated to be positively associated with immunological blood indices and negatively associated with birthweight in Landrace pigs (Huang et al., 2010). …”
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1060
The Decreased Treg Cells Number Associated with Retinal Lesion Size in Ocular Toxoplasmosis
Published 2024-01-01“…The imbalance of the immune response is an important factor contributing to the incidence of ocular toxoplasmosis (OT). …”
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