Association of CD24, CD27, and co-stimulatory molecules CD80 immunological marker expression on B-cells of human peripheral blood with development of celiac disease by Rahab Abd-Ali Al-Madany, Noor Abdulameer Oudah

“…CONCLUSION: These findings suggest that numerical deficiency of CD24, CD27, and CD80 expression on B-cells in the peripheral blood mononuclear cell population, that may involve the loss of auto-tolerance that plays an important role in the immune response associated with inflammation and tissue damage in celiac disease. …”
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Gastrointestinal Pathobionts in Pediatric Crohn’s Disease Patients by Rachel V. Purcell, Nadeem O. Kaakoush, Hazel M. Mitchell, John F. Pearson, Jacqueline I. Keenan

“…CD is thought to arise due to an immune response to environmental factors. The role of bacteria in CD has recently been highlighted, and here, we examine the prevalence of two bacterial species, enterotoxigenic Bacteroides fragilis (ETBF) and Fusobacterium nucleatum, implicated in gastrointestinal pathologies, in a pediatric CD cohort. …”
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The Potential use of a Curcumin-Piperine Combination as an Antimalarial Agent: A Systematic Review by Shafia Khairani, Nisa Fauziah, Hesti Lina Wiraswati, Ramdan Panigoro, Endang Yuni Setyowati, Afiat Berbudi

“…Curcumin is a potent antioxidant, damages parasite DNA, and may promote an immune response against Plasmodium by increasing reactive oxygen species (ROS), while piperine is also a potent antioxidant that potentiates the effects of curcumin. …”
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Holding the Inflammatory System in Check: TLRs and Their Targeted Therapy in Asthma by Zhiyong Dong, Lingxin Xiong, Weijie Zhang, Peter G. Gibson, Ting Wang, Yanjiao Lu, Guoqiang Wang, Hui Li, Fang Wang

“…TLRs are the primary proteins associated with the innate and adaptive immune responses to these fatal factors and play an important role in recognizing pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), which initiates the downstream immune response. …”
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Exclusive Cutaneous and Subcutaneous Sarcoidal Granulomatous Inflammation due to Immune Checkpoint Inhibitors: Report of Two Cases with Unusual Manifestations and Review of the Lit... by Narciss Mobini, Rummit Dhillon, Jason Dickey, Jordan Spoon, Kaviyon Sadrolashrafi

“…The primary target antigens are cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4), a downregulator of T-cell activation, and programmed cell death-1 receptor (PD-1), a regulator of T-cell proliferation. This enhanced immune response can induce autoimmune adverse effects in many organs. …”
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Alterations of the Gut Microbiome in Chinese Zhuang Ethnic Patients with Sepsis by Jieyang Yu, Hongping Li, Jingjie Zhao, Yanhua Huang, Chunlei Liu, Pengfei Yang, Dinggui Lu, Jian Song, Lingzhang Meng

“…Sepsis is characterized as a dysregulated host immune response to infection and has been known to be closely associated with the gut microbiome. …”
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Elevated Circulating IL-1<mml:math> <mml:mi>&#x03B2;</mml:mi> </mml:math> and TNF-Alpha, and Unaltered IL-6 in First-Trimester Pregnancies Complicated by Threatened Abortion With...

“…It is concluded that in first-trimester TACP with adverse outcome, a distinct immune response, as reflected by elevated maternal IL-1<mml:math> <mml:mi>&#x03B2;</mml:mi> </mml:math>, TNF-alpha, and unaltered IL-6 levels, is relevant to a negative obstetric outcome.…”
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The Effect of Age and Occupation on the Seroprevalence of Helicobacter pylori Infection by GI Perez-Perez, T Marrie, H Inouye, T Shimoyama, G Marshall, G Meiklejohn, MJ Blaser

“…The seroprevalence did not decrease in elderly persons (60 to 99 years), indicating a persistent immune response. More detailed analysis was perfom1ed on the Canadian population. …”
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Identification of Molecular Subtypes and Prognostic Features of Breast Cancer Based on TGF-β Signaling-related Genes by Jia Qu, Mei-Huan Wang, Yue-Hua Gao, Hua-Wei Zhang

“…Additionally, an unsupervised clustering algorithm was applied to categorize BC patients into two distinct groups based on the five TSRGs, with a focus on immune response and overall survival (OS). Further investigations were conducted to explore variations in pharmacotherapy and the tumor microenvironment across different patient cohorts and clusters. …”
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Cryptosporidiosis in a Zoonotic Gastrointestinal Disorder Perspective by Thivya Balendran, Devika Iddawela, Sajanee Lenadora

“…Therefore, with the objective of providing an in-depth analysis of Cryptosporidiosis in immunocompromised patients, this review presents a comprehensive understating of the prevalence, risk factors, pathophysiology of Cryptosporidium infection, clinical presentation in the immunocompromised, the immune response of the host, diagnostic methods performed in laboratory settings, possible treatments, and prevention methods, which can be used for further studies. …”
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The Role of TLR4 on B Cell Activation and Anti-β2GPI Antibody Production in the Antiphospholipid Syndrome by Si Cheng, Haibo Wang, Hong Zhou

“…In this paper, we aim to review the functions of TLR4 in B cell immune response and antibody production in autoimmune disease APS and try to find a new way for the prevention and treatment of APS.…”
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The Immunological Plasmodium falciparum Malaria Characteristics of Children in Tajikistan Republic by Nighina M. Khodzhaeva, Alla M. Baranova, Anatoly K. Tokmalaev

“…The imbalance of cytokine profile is an important pathogenic factor in the development of severe and recurrent forms of the disease, since the formation of a defective immune response to parasitic antigens contributes to adverse outcomes. …”
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Immunological Approaches and Different Strategies for Vaccine Development Against SARS-COV-2 by Muhammed Babakir-Mina

“…On the base on immune response detected in recovered patients, scientists have started to develop the vaccines. …”
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Porphyromonas gulae and canine periodontal disease: Current understanding and future directions by Kyu Hwan Kwack, Eun-Young Jang, Cheul Kim, Young-Suk Choi, Jae-Hyung Lee, Ji-Hoi Moon

“…Control strategies discussed include polyphosphate to disrupt haeme/iron utilization, clindamycin with interferon alpha to reduce bacterial load and enhance the immune response, and a protease inhibitor. Further research is needed to understand strain-level diversity of virulence factors and interactions between P. gulae and other oral bacteria, particularly Fusobacterium nucleatum, a common pathogen in both dogs and humans. …”
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Foot-and-mouth disease in Asia by Md. Abdur Rahman, Farah Zereen, Md. Liton Rana, Md. Golzar Hossain, Masaru Shimada, Sukumar Saha

“…This review discusses the prevalence of various FMD virus (FMDV) serotypes across Asia, along with the transmission modes, pathogenesis, immune response, and immune suppression by FMDV. Additionally, the review explores FMD diagnosis, prevention, and control strategies, and highlights future opportunities for research aimed at developing strain-specific viral and bacterial combined vaccines.…”
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Effect of innate and induced immunity on infectious bursal disease pathogenesis by A. N. Semina

“…Recent studies, however, demonstrated the role of the enhanced immune response at early stage of the infection along with increased production of cytokine storm-inducing promediators. …”
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Immunoprotective Effect of Seabuckthorn (Hippophae rhamnoides) and Glucomannan on T-2 Toxin-Induced Immunodepression in Poultry by T. Ramasamy, C. Varshneya, V. C. Katoch

“…A significant (P<.05) increase in DTH reaction and non-specific immune response was seen in seabuckthorn and glucomannan fed birds. …”
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Respiratory Syncytial Virus Infections in Infants Affected by Primary Immunodeficiency by Marcello Lanari, Silvia Vandini, Maria Grazia Capretti, Tiziana Lazzarotto, Giacomo Faldella

“…Respiratory syncytial virus (RSV) is one of the most frequent pathogens during early infancy and the infection is more severe in immunocompromised infants than in healthy infants, as a result of impaired T- and B-cell immune response unable to efficaciously neutralize viral replication, with subsequent increased viral shedding and potentially lethal lower respiratory tract infection. …”
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Trypanosoma cruzi SSP4 Amastigote Protein Induces Expression of Immunoregulatory and Immunosuppressive Molecules in Peripheral Blood Mononuclear Cells by Yadira Morán-Utrera, Aracely López-Monteon, José Luis Rosales-Encina, Enrique Méndez-Bolaina, Angel Ramos-Ligonio

“…Parasite molecules that regulate the host immune response during Chagas’ disease have not been fully identified, particularly proteins of the amastigote stage. …”
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Diagnosis of bovine viral diarrhea in Bubalus bubalis dairy farms by Oriana Gavidia, Rosaura Pérez-Gil

“…These results show a humoral immune response against potential BVD infections (regardless of the milk yield) since p80 is a non-structural protein that manifests during viral replication. …”
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