Application of probiotic microcapsules Bacillus cereus BR2 with different doses for the prevention of Aeromonas hydrophila NFC1 infection in catfish Clarias sp. by Nurul Faoziyatunnisa, Munti Yuhana, Dinamella Wahjuningrum, Sri Nuryati, Usamah Afiff

“… This study aims to analyze the administration of microencapsulated probiotic Bacillus cereus BR2 through feed atdifferent doses on the survival, immune response, and digestive enzyme activity of catfish Clarias sp. infected with Aeromonas hydrophila NFC1. …”
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Unraveling the impact of SARS-CoV-2 mutations on immunity: insights from innate immune recognition to antibody and T cell responses by Rafael Bayarri-Olmos, Rafael Bayarri-Olmos, Adrian Sutta, Adrian Sutta, Anne Rosbjerg, Anne Rosbjerg, Mie Mandal Mortensen, Charlotte Helgstrand, Per Franklin Nielsen, Laura Pérez-Alós, Beatriz González-García, Laust Bruun Johnsen, Finn Matthiesen, Thomas Egebjerg, Cecilie Bo Hansen, Alessandro Sette, Alessandro Sette, Alba Grifoni, Ricardo da Silva Antunes, Peter Garred, Peter Garred

“…These findings extend our understanding of the complex interplay between viral adaptation and immune response, underscoring the importance of considering MBL interactions, immune imprinting, and viral evolution dynamics in developing new vaccine and treatment strategies.…”
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Neutralizing antibody test supports booster strategy for young individuals after SARS-CoV-2 Omicron breakthrough by Yichuan Yao, Yunru Yang, Qiqin Wu, Mengyao Liu, Wei Bao, Qiutong Wang, Meijun Cheng, Yunuo Chen, Yiting Yu, Yuan Cai, Mei Zhang, Jingxue Yao, Hongliang He, Changjiang Jin, Changcheng Zheng, Tengchuan Jin, Dali Tong

“…It is important to study the immune response of SARS-CoV-2 Omicron variant due to its remarkable ability to escape the majority of existing SARS-CoV-2 neutralizing antibodies. …”
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Impact of SARS-CoV-2 vaccination and of seasonal variations on the innate immune inflammatory response by Hend Jarras, Isalie Blais, Benjamin Goyer, Wilfried W. Bazié, Wilfried W. Bazié, Henintsoa Rabezanahary, Mathieu Thériault, Kim Santerre, Marc-André Langlois, Jean-François Masson, Joelle N. Pelletier, Joelle N. Pelletier, Nicholas Brousseau, Nicholas Brousseau, Denis Boudreau, Sylvie Trottier, Sylvie Trottier, Mariana Baz, Mariana Baz, Caroline Gilbert, Caroline Gilbert

“…IntroductionThe innate immune response is an important first checkpoint in the evolution of an infection. …”
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CD8 Knockout Mice Are Protected from Challenge by Vaccination with WR201, a Live Attenuated Mutant of Brucella melitensis by Samuel L. Yingst, Mina Izadjoo, David L. Hoover

“…Further, primary Brucella infection was not exacerbated in perforin knockout and Fas-deficient mice and these animals’ anti-Brucella immune responses were indistinguishable from those of normal mice. …”
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Peroxisome Proliferator-Activated Receptor-γ in Thyroid Autoimmunity by Silvia Martina Ferrari, Poupak Fallahi, Roberto Vita, Alessandro Antonelli, Salvatore Benvenga

“…An increasing body of evidence shows the importance of the (C-X-C motif) receptor 3 (CXCR3) and cognate chemokines (C-X-C motif) ligand (CXCL)9, CXCL10, and CXCL11, in the T helper 1 immune response and in inflammatory diseases such as thyroid autoimmune disorders. …”
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Recurrence of Herpetic Keratitis after COVID-19 Vaccination: A Report of Two Cases by Ali Mahdavi Fard, Jeffrey Desilets, Sangita Patel

“…The general activation of the T-cell-mediated immune response and proinflammatory cytokines such as IFNγ may underlie the role of the COVID vaccines in reactivation of herpetic stromal keratitis and the clinical findings in our reported cases.…”
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Induced Neurocysticercosis in Rhesus Monkeys (Macaca mulatta) Produces Clinical Signs and Lesions Similar to Natural Disease in Man by N. Chowdhury, A. Saleque, N. K. Sood, L. D. Singla

“…It was concluded that the inflammatory and immune response exerted by the host against cysticerci, in turn, led to histopathological lesions and the resultant clinical signs thereof.…”
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Development of a multi-epitope chimeric vaccine in silico against Babesia bovis, Theileria annulata, and Anaplasma marginale using computational biology tools and reverse vaccinolo... by Amam Zonaed Siddiki, Sabreena Alam, Farhan Fuad Bin Hossen, Md Abdul Alim

“…Immune simulation was also performed to determine the potentiality of the chimeric vaccine for eliciting an immune response. The best-designed chimeric vaccine construct was then reverse transcribed and adapted for the host E. coli K12 strain which was later inserted into the pET28a (+) vector for the cloning and expression of the vaccine. …”
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Allogeneic Mesenchymal Stem Cell Treatment Induces Specific Alloantibodies in Horses by Sean D. Owens, Amir Kol, Naomi J. Walker, Dori L. Borjesson

“…It is unknown whether horses that receive allogeneic mesenchymal stem cells (MSCs) injections develop specific humoral immune response. Our goal was to develop and validate a flow cytometric MSC crossmatch procedure and to determine if horses that received allogeneic MSCs in a clinical setting developed measurable antibodies following MSC administration. …”
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Costimulatory Pathways: Physiology and Potential Therapeutic Manipulation in Systemic Lupus Erythematosus by Nien Yee Kow, Anselm Mak

“…Amongst the antigen-presenting cells and lymphocytes, and between lymphocytes, the costimulatory pathways which involve mutual exchange of information and signalling play an essential role in initiating, perpetuating, and, eventually, attenuating the proinflammatory immune response. In this review, advances in the knowledge of established costimulatory pathways such as CD28/CTLA-4-CD80/86, ICOS-B7RP1, CD70-CD27, OX40-OX40L, and CD137-CD137L as well as their potential roles involved in the pathophysiology of SLE will be discussed. …”
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Local C-Reactive Protein Expression in Obliterative Lesions and the Bronchial Wall in Posttransplant Obliterative Bronchiolitis by Outi E. Päiväniemi, Paula K. Maasilta, Tiina L. S. Vainikka, Hanni S. Alho, Pekka J. Karhunen, Ulla-Stina Salminen

“…Influx of CD4+ (P<.001) and CD8+ (P<.0001) cells demonstrated allograft immune response. CRP positivity simultaneously increased in the bronchial walls (P<.01), in macrophages, myofibroblasts, and endothelial cells. …”
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Feasibility and Limits of Magnetically Labeling Primary Cultured Rat T Cells with Ferumoxides Coupled with Commonly Used Transfection Agents by Cedric Berger, Martin Rausch, Philipp Schmidt, Markus Rudin

“…Macrophages are effectors of the immune response, their appearance being orchestrated by activated T lymphocytes. …”
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Beyond immortality: Epstein–Barr virus and the intricate dance of programmed cell death in cancer development by Arezoo Esmaeili, Prankur Awasthi, Samira Tabaee

“…This comprehensive review delves into the intricate role of programmed cell death in Epstein–Barr virus (EBV)-associated malignancies, focusing on the sophisticated interplay between viral mechanisms and the host's immune response. The central objective is to unravel how EBV exerts control over cell death pathways such as apoptosis, ferroptosis, and autophagy, thereby fostering its persistence and oncogenic potential. …”
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Serum Cytokine Profile in a Patient Diagnosed with Dysferlinopathy by Svetlana F. Khaiboullina, Ekaterina V. Martynova, Sergey N. Bardakov, Mikhail O. Mavlikeev, Ivan A. Yakovlev, Arthur A. Isaev, Roman V. Deev, Albert A. Rizvanov

“…Together, these data on serum cytokine profile of this dysferlinopathy patient suggest immune response activation, which could explain leukocyte infiltration in the muscle tissue.…”
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Unraveling the Effect of Immunogenicity on the PK/PD, Efficacy, and Safety of Therapeutic Proteins by Alison Smith, Hugh Manoli, Stacey Jaw, Kimberley Frutoz, Alan L. Epstein, Leslie A. Khawli, Frank-Peter Theil

“…We set out to describe what is known and unknown about the mechanisms underlying the interplay between antigenicity and immune response and their effect on the safety, efficacy, pharmacokinetics, and pharmacodynamics of these therapeutic agents.…”
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Oral administration of egg white ovotransferrin prevents osteoporosis in ovariectomized rats by Nan Shang, Xiaoyu Bao, Michael Doschak, Jianping Wu

“…In addition to its direct regulatory role on bone turnover, ovotransferrin supplementation might benefit osteoporosis prevention by inhibiting adipogenesis, and regulating immune response. Our results suggested the potential application of ovotransferrin as a functional food ingredient on the prevention of osteoporosis.…”
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Dengue infection changes the expressions of CD154 and CD148 in human platelets by Sayali Vedpathak, Sonali Palkar, AkhileshChandra Mishra, Vidya A Arankalle, Shubham Shrivastava

“…Upon pathogen recognition, platelets rapidly modulate the expression of adhesion molecules to trigger immune cell interactions and regulate the immune response. In this study, we aimed to examine the expression levels of three molecules, CD151, CD154, and CD148 on platelets in dengue patients. …”
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Cancer-Associated Immune Resistance and Evasion of Immune Surveillance in Colorectal Cancer by Pietro Parcesepe, Guido Giordano, Carmelo Laudanna, Antonio Febbraro, Massimo Pancione

“…Recent works reveal that expression of immune antigens (PDL1, CD47, CD73, CD14, CD68, MAC387, CD163, DAP12, and CD15) by tumor cells “immune resistance,” combined with prometastatic function of nonmalignant infiltrating cells, may represent a strategy to overcome the rate-limiting steps of metastatic cascade through (a) enhanced interactions with protumorigenic myeloid cells and escape from T-dependent immune response mediated by CD8+ and natural killer (NK) cells; (b) production of immune mediators that establish a local and systemic tumor-supportive environment (premetastatic niche); (c) ability to survive either in the peripheral blood as circulating tumor cells (CTCs) or at the metastatic site forming a cooperative prometastatic loop with foreign “myeloid” cells, macrophages, and neutrophils, respectively. …”
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Study on the response mechanism of MicroRNA novel-13 and novel-44 to Vibrio parahaemolyticus infection in Pinctada fucata martensii by Chao Jie Li, Qi Yuan Zhang, Bin Zhang, Hai Ying Liang, Li Ning Ma, Muhammad Salman

“…MicroRNAs (miRNAs), as an innovative and potent regulator of immune function, play a pivotal role in the immune response of pearl oysters to external stimuli and are a potent marker for the response of P. f. martensii to infection. …”
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